Drug Discovery World
FEBRUARY 8, 2024
In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. The event aimed to help the audience understand the AAV workflow, from upstream methods for AAV production and validation to downstream analysis of the packaged product for enhanced therapeutic development.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
Following the arrival of the first farmers in Scandinavia 5,900 years ago, the hunter-gatherer population was wiped out within a few generations, according to a new study. The results, which are contrary to prevailing opinion, are based on DNA analysis of skeletons and teeth found in what is now Denmark.
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Drug Discovery World
FEBRUARY 8, 2024
For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode five, Solving the diagnostic odyssey with multi-omics. Catherine Brownstein is an Assistant Professor in Pediatrics at Harvard Medical School and the Assistant Director of the Molecular Genetics Core Facility at Boston Children’s Hospital.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
Researchers have uncovered the first direct evidence that the West Antarctic Ice Sheet shrunk suddenly and dramatically at the end of the Last Ice Age, around eight thousand years ago. The evidence, contained within an ice core, shows that in one location the ice sheet thinned by 450 meters -- that's more than the height of the Empire State Building -- in just under 200 years.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
FEBRUARY 8, 2024
For this year’s SLAS2024 conference in Boston (which takes place 3-7 February), DDW’s Megan Thomas narrates articles from the DDW SLAS2024 supplement as part of the DDW Events podcast series. This is episode five, Solving the diagnostic odyssey with multi-omics. Catherine Brownstein is an Assistant Professor in Pediatrics at Harvard Medical School and the Assistant Director of the Molecular Genetics Core Facility at Boston Children’s Hospital.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2023 -- Could drugs that give a boost to men's sexual performance help them stave off Alzheimer's disease?That's the main finding from a study suggesting that erectile dysfunction meds like Cialis, Levitra and Viagra might lower.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
FEBRUARY 8, 2024
The German biotech will invest $200 million in Autolus — funds that, along with a $50 million fee, will give it licensing opportunities and access to supply infrastructure.
Drug Discovery World
FEBRUARY 8, 2024
COUR Pharmaceuticals has secured $105 million in a Series A investment round co-led by Lumira Ventures and Alpha Wave Ventures. The funds will be used to support the advancement of COUR’s myasthenia gravis (MG) and type 1 diabetes (T1D) product candidates into Phase IIa clinical trials. The Roche Venture Fund, Pfizer (as part of the Pfizer Breakthrough Growth Initiative), Bristol Myers Squibb, Angelini Ventures, and the JDRF T1D Fund also contributed to the financing.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
A new fusion of materials, each with special electrical properties, has all the components required for a unique type of superconductivity that could provide the basis for more robust quantum computing.
On Medicine
FEBRUARY 8, 2024
Funded by the National Institute for Health and Care Research (NIHR), the CHARMER team have worked with healthcare professionals and older people, a patient group undoubtedly under-served by clinical research, to develop an approach to support geriatricians (hospital doctors who care for older people) and pharmacists to undertake more proactive deprescribing with older people whilst they are in hospital.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
Scientists have discovered that nighttime air pollution -- coming primarily form car exhaust and power plant emissions -- is responsible for a major drop in nighttime pollinator activity. Nitrate radicals (NO3) in the air degrade the scent chemicals released by a common wildflower, drastically reducing the scent-based cues that its chief pollinators rely on to locate the flower.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- Two studies that warned of the harms of the abortion pill have been retracted by the journals' publisher over flaws in the data and conflicts of interest among the researchers.Complicating matters even further, the papers.
Drug Target Review
FEBRUARY 8, 2024
This eBook introduces a new approach to the analysis of immune cell function. Providing single-cell resolution that reveals the heterogeneity of immune cell populations, these workflows combine an innovative application of microfluidics technology with single-cell format flow cytometry of living cells. Get ready to discover how Xdrop DE50 droplets can be used to encapsulate individual immune cells and deliver them for incubation, analysis, and retrieval.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- Dr. Anthony Fauci, who helped Americans navigate the HIV/AIDS epidemic and the COVID-19 pandemic, will reflect on his career in a memoir set for release this summer. His publisher, Viking, announced that the book, titled.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Target Review
FEBRUARY 8, 2024
Researchers from the Cleveland Clinic have identified changes in tumour-related bacteria, which have revealed possible new strategies to tackle the increase of young-onset colorectal cancer (CRC), which refers to CRC incidence in patients under 50 years old. CRC is one of the leading causes of cancer related mortality worldwide, with some of its risk factors being obesity, red meat consumption, alcohol and tobacco. 1 Despite this condition being easy to surgically treat and target with chemother
Perficient: Drug Development
FEBRUARY 8, 2024
The Celtics vs. The Lakers, Boston Red Sox vs. New York Yankees, Frazier vs. Ali. I think all of us have our favorite epic rivalries that stick with us. But what makes rivalries so engaging? Some say it’s the bragging rights, some say it’s the passion, and others say it’s because rivalries tend to bring out the best in each competitor. I tend to lean towards all the above as being the catalyst for why we find them so engaging.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- No one's brain is as sharp at 60 as it was at 20. However, new research supports the notion that folk's brains can make subtle adjustments with age to compensate for that decline.A team of British researchers has found.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
Cutting-edge research converted waste carbon dioxide into a potential precursor for chemicals and carbon-free fuel.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- The position in bed of stroke victims' heads could influence how well they’ll fare in upcoming surgery to remove a blood clot from their brain, a new study finds.Hospital beds for stroke patients are typically set up to.
SCIENMAG: Medicine & Health
FEBRUARY 8, 2024
Researchers from Tokyo Medical and Dental University (TMDU) overcome scientific roadblocks and develop a model to assess the biology of the human placental barrier Credit: Department of Diagnostic and Therapeutic Systems Engineering, TMDU Researchers from Tokyo Medical and Dental University (TMDU) overcome scientific roadblocks and develop a model to assess the biology of the human […]
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- Adding blood thinners to clot-busting drugs does not improve outcomes for stroke patients, a new study claims.Doctors had hoped that combining the two types of medications would improve treatment of stroke, as a similar.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
If you're looking for a long-term relationship or to boost your social status, lower your pitch, according to researchers studying the effects of voice pitch on social perceptions. They found that lower voice pitch makes women and men sound more attractive to potential long-term partners, and lower voice pitch in males makes the individual sound more formidable and prestigious among other men.
Drugs.com
FEBRUARY 8, 2024
THURSDAY, Feb. 8, 2024 -- A doctor or nurse might be the only person capable of convincing a vaccine-hesitant person to get the COVID jab, a new study shows.
BioPharma Drive: Drug Pricing
FEBRUARY 8, 2024
The company is one of three preclinical biotechs to successfully go public since last summer, but it pulled in significantly less than others who’ve debuted with more advanced medicines.
Broad Institute
FEBRUARY 8, 2024
Researchers uncover genetic factors for severe Lassa fever By Allessandra DiCorato February 8, 2024 Breadcrumb Home Researchers uncover genetic factors for severe Lassa fever New findings from an international collaboration pave the way for studies of highly infectious diseases in Africa such as Ebola. By Allessandra DiCorato February 8, 2024 Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland Scanning electron image of the Lassa virus budding off a cell.
addgene Blog
FEBRUARY 8, 2024
“Off-target effects” a vague catch-all term for unintended consequences in an experiment. For CRISPR work, this often means DNA cleavage at unanticipated sites. While off-target effects are nearly impossible to eliminate, it ’ s essential to understand them in order to design the most specific assays possible. In this blog, we will discuss when off-targets can be an issue in CRISPR, how to predict and minimize them, and ways to control for and quantify them when they can’t be avoided.
SCIENMAG: Medicine & Health
FEBRUARY 8, 2024
The onset of psychosis can be predicted before it occurs, using a machine-learning tool which can classify MRI brain scans into those who are healthy and those at risk of a psychotic episode.
Science Daily: Pharmacology News
FEBRUARY 8, 2024
Researchers have developed a spiral-shaped lens that maintains clear focus at different distances in varying light conditions. The new lens works much like progressive lenses used for vision correction but without the distortions typically seen with those lenses. It could help advance contact lens technologies, intraocular implants for cataracts and miniaturized imaging systems.
BioPharma Drive: Drug Pricing
FEBRUARY 8, 2024
The company’s haul is the latest sign brain drugs are recapturing the interest of investors after years of being passed over for other areas of research.
Drugs.com
FEBRUARY 8, 2024
Thursday, Feb. 8, 2024 -- The U.S. Centers of Disease Control and Prevention is investigating an outbreak of gastrointestinal illness aboard a luxury cruise ship that sailed out of San Francisco on Wednesday. More than 150 people on the Queen.
BioPharma Drive: Drug Pricing
FEBRUARY 8, 2024
Forced into testifying by Senate HELP chair Bernie Sanders, the heads of Bristol Myers Squibb, J&J and Merck largely avoided major missteps.
Drug Patent Watch
FEBRUARY 8, 2024
Annual Drug Patent Expirations for GAVRETO Gavreto is a drug marketed by Genentech Inc and is included in one NDA. It is available from one supplier. There are two patents… The post New patent for Genentech Inc drug GAVRETO appeared first on DrugPatentWatch - Make Better Decisions.
BenchSci
FEBRUARY 8, 2024
Earlier this month, I traveled across North America and the UK to meet our 340 team members. Every year in January, we kick off the year with our “Roadshow”, where I meet our team in person and share our accomplishments and learning from the previous year and where we are going next. This year, you could feel even more excitement in the room than in previous years as we are accelerating our efforts to integrate even more Generative AI (GenAI) capabilities into our ASCEND Platform.
Drug Patent Watch
FEBRUARY 8, 2024
Annual Drug Patent Expirations for VEKLURY Veklury is a drug marketed by Gilead Sciences Inc and is included in one NDA. It is available from one supplier. There are thirteen… The post New patent for Gilead Sciences drug VEKLURY appeared first on DrugPatentWatch - Make Better Decisions.
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