Wed.Apr 24, 2024

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Cells may possess hidden communication system

Science Daily: Pharmacology News

Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations? A new study is answering that question by challenging our understanding of how cells function. A team of researchers suggests that cells possess a previously unknown information processing system that allows them to make rapid decisions independent of their genes.

Research 141
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Science Reveals How Aspirin Prevents Colon Cancer

Drugs.com

WEDNESDAY, April 24, 2024 -- Long-term daily use of aspirin has been known to prevent colon cancer, but up to now it’s been unclear why that is.Now, researchers think they understand how aspirin acts against colon cancer, a new study says.Aspirin.

Science 124
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Use of acid reflux drugs linked to higher risk of migraine

Science Daily: Pharmacology News

People who take acid-reducing drugs may have a higher risk of migraine and other severe headache than people who do not take these medications, according to a new study. The acid-reducing drugs include proton pump inhibitors such as omeprazole and esomeprazole, histamine H2-receptor antagonists, or H2 blockers, such as cimetidine and famotidine, and antacid supplements.

Drugs 130
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New Rules Mean 3.6 Million Americans Could Get Wegovy Via Medicare, Costing Billions

Drugs.com

WEDNESDAY, April 24, 2024 -- A budget-busting 3.6 million Medicare recipients could now be eligible for coverage of the weight-loss drug Wegovy, a new KFF analysis says.That’s because the U.S. Food and Drug Administration has approved the use of.

Drugs 119
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Why can't robots outrun animals?

Science Daily: Pharmacology News

Robotics engineers have worked for decades and invested many millions of research dollars in attempts to create a robot that can walk or run as well as an animal. And yet, it remains the case that many animals are capable of feats that would be impossible for robots that exist today.

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Deconstructing the Diligence Process: An Approach to Vetting New Product Theses

LifeSciVC

By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Ever wondered what goes into diligencing a new idea, program, company, or platform? While each diligence is unique and every investor will have their own approach, below are some considerations that may be more “typical” in a diligence. I will emphasize the obvious disclaimer before diving in – this framework is merely meant to be exemplary and there are always nuances and exceptions unique to eac

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Trying 'Magic Mushroom' Drug to Ease Depression? It Has Side Effects

Drugs.com

WEDNESDAY, April 24, 2024 -- Many people with tough-to-treat depression may be trying psilocybin, the active ingredient in magic mushrooms, as an alternative to antidepressants.Thinking that it's a "natural" drug, folks might assume it comes.

Drugs 116
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A simple 'twist' improves the engine of clean fuel generation

Science Daily: Pharmacology News

Researchers have found a way to super-charge the 'engine' of sustainable fuel generation -- by giving the materials a little twist. The researchers are developing low-cost light-harvesting semiconductors that power devices for converting water into clean hydrogen fuel, using just the power of the sun. These semiconducting materials, known as copper oxides, are cheap, abundant and non-toxic, but their performance does not come close to silicon, which dominates the semiconductor market.

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Patient Gets First-Ever Pig Kidney Transplant Plus Heart Pump

Drugs.com

WEDNESDAY, April 24, 2024 -- New Jersey native Lisa Pisano was staring down the end of her days.The 54-year-old had heart failure and end-stage kidney disease, but several chronic medical conditions excluded her as a candidate for heart and kidney.

Disease 105
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Discovering cancers of epigenetic origin without DNA mutation

Science Daily: Pharmacology News

A research team has discovered that cancer, one of the leading causes of death worldwide, can be caused entirely by epigenetic changes, in other words, changes that contribute to how gene expression is regulated, and partly explain why, despite an identical genome, an individual develops very different cells (neurons, skin cells, etc.).

DNA 110
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Infertility Is Rising Among Young Married Women

Drugs.com

WEDNESDAY, April 24, 2024 -- The percentage of married American women under the age of 50 who are infertile rose between 2011 and 2019, new government statistics show.Data from the National Survey of Family Growth show that "the percentage of.

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Making diamonds at ambient pressure

Science Daily: Pharmacology News

Researchers have grown diamonds under conditions of 1 atmosphere pressure and at 1025 degrees Celsius using a liquid metal alloy composed of gallium, iron, nickel, and silicon, thus breaking the existing paradigm. The discovery of this new growth method opens many possibilities for further basic science studies and for scaling up the growth of diamonds in new ways.

Science 110
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There's an 'Epidemic' of Loneliness Among U.S. Parents, Poll Finds

Drugs.com

WEDNESDAY, April 24, 2024 -- Anne Helms is one busy mom, constantly juggling the demands of working from home with parenting two young children.Despite that whirl of activity, Helms says she often feels isolated and lonely.“I work from home full.

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This salt battery harvests osmotic energy where the river meets the sea

Science Daily: Pharmacology News

Estuaries -- where freshwater rivers meet the salty sea -- are great locations for birdwatching and kayaking. In these areas, waters containing different salt concentrations mix and may be sources of sustainable, 'blue' osmotic energy. Researchers report creating a semipermeable membrane that harvests osmotic energy from salt gradients and converts it to electricity.

Research 110
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Almost 40% of Americans Live With Dirty Air: Report

Drugs.com

WEDNESDAY, April 24, 2024 -- Nearly 40% of Americans live where the air is polluted enough to harm them, a new report warns.In the American Lung Association's “State of the Air” report, released Wednesday, the number of people living with.

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Moderna turns to AI to change how its employees work

BioPharma Drive: Drug Pricing

An expanded partnership with OpenAI is helping Moderna embed custom-built AI chatbots in a wide range of research and business processes.

Research 120
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From Spreadsheet Chaos to Data Strategy Triumph with Perficient

Perficient: Drug Development

Uncovering the Challenge: Relying on Spreadsheets for Portfolio Analysis A leading wealth and asset management firm recently sought our financial services expertise for a critical challenge. Relying on complex spreadsheets for portfolio analysis, the firm faced operational hurdles due to immense computing demands. The Perficient Approach: Transforming Operations through Strategic Consulting Our team embraced the challenge, conducting a meticulous two-week analysis to uncover the root issue: a cu

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Human activities have an intense impact on Earth's deep subsurface fluid flow

Science Daily: Pharmacology News

Hydrologists predict human-induced underground fluid fluxes to rise with climate change mitigation strategies like carbon sequestration.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Fragments of Bird Flu Virus Found in U.S. Milk Supply

Drugs.com

WEDNESDAY, April 24, 2024 -- Bits of inactive bird flu virus have been discovered in samples of pasteurized milk from across the United States, health officials said Tuesday, although they stressed the viral fragments don't threaten humans.

Virus 104
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New research shows 'profound' link between dietary choices and brain health

Science Daily: Pharmacology News

New research has highlighted the profound link between dietary choices and brain health.

Research 142
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Black, Hispanic Americans Getting Savvier About CPR

Drugs.com

WEDNESDAY, April 24, 2024 -- Black and Hispanic Americans are gaining a better understanding of CPR, with a growing number expressing confidence they could use it to save a life, a new survey finds.About 44% of Black Americans now feel confident.

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Scientists unveil genetics behind development of gliding

Science Daily: Pharmacology News

Researchers explain the genomic and developmental basis of the patagium, the thin skin membrane that allows some mammalian species to soar through the air.

Research 108
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Biogen to invest more in launch of Alzheimer’s drug Leqembi

BioPharma Drive: Drug Pricing

Growing demand has convinced Biogen that it's worth expanding the sales force around Leqembi by 30%.

Drugs 124
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Eruption of mega-magnetic star lights up nearby galaxy

Science Daily: Pharmacology News

While ESA's satellite INTEGRAL was observing the sky, it spotted a burst of gamma-rays -- high-energy photons -- coming from the nearby galaxy M82. Only a few hours later, ESA's XMM-Newton X-ray space telescope searched for an afterglow from the explosion but found none. An international team realized that the burst must have been an extra-galactic flare from a magnetar, a young neutron star with an exceptionally strong magnetic field.

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$282 Billion: What Mental Illness Costs America Each Year

Drugs.com

WEDNESDAY, April 24, 2024 -- America’s mental health woes essentially serve as an annual economic downturn for the nation, a new study says.Mental illness costs the U.S. economy $282 billion every year, equivalent to the average economic.

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Survey finds loneliness epidemic runs deep among parents

Science Daily: Pharmacology News

A new national survey finds a broad majority of parents experience isolation, loneliness and burnout from the demands of parenthood, with many feeling a lack of support in fulfilling that role.

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CureVac to cut costs in restructuring

BioPharma Drive: Drug Pricing

The mRNA vaccine maker, which has lost most of its value since early 2021, is undergoing an “organizational redesign” that will involve the elimination of 150 positions.

Vaccine 67
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Condensed matter physics: Novel one-dimensional superconductor

Science Daily: Pharmacology News

In a significant development in the field of superconductivity, researchers have successfully achieved robust superconductivity in high magnetic fields using a newly created one-dimensional (1D) system. This breakthrough offers a promising pathway to achieving superconductivity in the quantum Hall regime, a longstanding challenge in condensed matter physics.

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Biogen: Don’t expect any big acquisitions this year

BioPharma Drive: Drug Pricing

While the company is eager to diversify, CEO Chris Viehbacher said that in the near-term any dealmaking would likely focus on collaborations and early-stage assets.

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These giant, prehistoric salmon had tusk-like teeth

Science Daily: Pharmacology News

Oncorhynchus rastrosus, a giant species of salmon that lived in the North American Pacific Northwest a few million years ago, sported a pair of front teeth that projected out from the sides of its mouth like tusks, according to a new study.

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Biogen sees ‘encouraging’ trends for postpartum depression drug

BioPharma Drive: Drug Pricing

First quarter sales of Zurzuvae doubled consensus estimates, though analysts are skeptical whether the better-than-expected launch will continue.

Drugs 73
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Leveraging Data Cloud for Medical Devices

Perficient: Drug Development

From patient records to medical device telemetry, the volume and diversity of data generated for medical device companies can be staggering. However, harnessing this data to its full potential remains a significant challenge for many. Healthcare organizations, including medical device companies, grapple with dispersed data across various departments and technologies.

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Endeavor pulls in $132M to back cancer, lung disease drugs

BioPharma Drive: Drug Pricing

Led by the founder of a biotech Celgene acquired for $7 billion, the startup is developing two prospects that originated in the labs of other drugmakers.

Disease 70