Science Daily: Pharmacology News
MARCH 20, 2024
A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.
Broad Institute
MARCH 20, 2024
Spatial study of lung cancer reveals immune markers of response to immunotherapy By Corie Lok March 20, 2024 Breadcrumb Home Spatial study of lung cancer reveals immune markers of response to immunotherapy Researchers visualize how immune cells are spatially organized within tumors and show that certain immune “hubs” are linked to better treatment responses.
Science Daily: Pharmacology News
MARCH 20, 2024
A new study has shown that food-seeking cells exist in a part of a mouse's brain usually associated with panic -- but not with feeding. Activating a selective cluster of these cells kicked mice into 'hot pursuit' of live and non-prey food, and showed a craving for fatty foods intense enough that the mice endured foot shocks to get them, something full mice normally would not do.
Chemical Biology and Drug Design
MARCH 20, 2024
Three galactosamine (Gal) and docetaxel (DTX) conjugates with different linkers were synthesized. Among these three conjugates, DTX-(DSeDPA-Gal) 2 with diselenide linkages exhibits enhanced GSH responsiveness, high cytotoxicity and selectivity against HepG2 cells. DTX-(DSeDPA-Gal) 2 developed in this study has been proven to be an effective DTX conjugate for selective killing hepatoma cells.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MARCH 20, 2024
If it walks like a particle, and talks like a particle. it may still not be a particle. A topological soliton is a special type of wave or dislocation which behaves like a particle: it can move around but cannot spread out and disappear like you would expect from, say, a ripple on the surface of a pond. Researchers now demonstrate the atypical behavior of topological solitons in a robotic metamaterial, something which in the future may be used to control how robots move, sense their surroundings
ASPET
MARCH 20, 2024
Adult-onset hypothyroidism impairs normal brain function. Research on animal models of hypothyroidism has revealed critical information on how deficiency of thyroid hormones impacts the electrophysiological and molecular functions of the brain, which lead to the well-known cognitive impairment in untreated hypothyroid patients. Currently, such information can only be obtained from experiments on animal models of hypothyroidism.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
ASPET
MARCH 20, 2024
DNA topoisomerase IIβ (TOP2β/180; 180 kDa) is a nuclear enzyme that regulates DNA topology by generation of short-lived DNA double-strand breaks primarily during transcription. TOP2β/180 can be a target for DNA damage-stabilizing anticancer drugs, whose efficacy is often limited by chemoresistance. Our laboratory previously demonstrated reduced levels of TOP2β/180 (and the paralog TOP2α/170) in an acquired etoposide-resistant K562 clonal cell line, K/VP.5 in part due to
Science Daily: Pharmacology News
MARCH 20, 2024
Infectious diseases specialists call the medical field to be ready to deal with the impact of climate change on spreading diseases, such as malaria, Valley fever, E. coli and Lyme disease.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- For the first time, the United States has fallen out of the top 20 spots on the annual world's happiest nations list.Americans are now No. 23, far behind the top five countries -- Finland (No.
Science Daily: Pharmacology News
MARCH 20, 2024
More than 7,000 years ago, people navigated the Mediterranean Sea using technologically sophisticated boats, according to a new study.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
MARCH 20, 2024
The company claims its approach could yield more effective and safer T-cell engagers, a type of cancer medicine that’s attracted significant interest from drugmakers in recent years.
Science Daily: Pharmacology News
MARCH 20, 2024
Detailed reports on thousands of artifacts pulled from 'Britain's Pompeii' reveals the surprisingly sophisticated domestic lives of Bronze Age Fen folk some 3,000 years ago -- from home interiors to recipes, clothing, kitchenware and pets.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- Killing off large tumors by freezing them could become an effective means of fighting difficult-to-treat breast cancer, a new study says.Only 10% of people who underwent the minimally invasive procedure, called.
Science Daily: Pharmacology News
MARCH 20, 2024
Researchers showed in 2022 that heat index calculations by NOAA based on analyses from the 1970s don't adequately reflect the heat stress humans feel during the extremes of heat and humidity accompanying climate change. Using their revised heat index, the researchers looked at Texas's summer 2023 heat wave and found that the 3 degree F rise in global temperatures has increased the state's heat index as much as 11 degrees F on the hottest days.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- Precisely delivered ultrasound could be an effective treatment for prostate cancer, with high-frequency sound waves heating and killing off cancer cells, a new study says.The treatment killed off all prostate cancer.
Science Daily: Pharmacology News
MARCH 20, 2024
Scientists have created a giant quantum vortex to mimic a black hole in superfluid helium that has allowed them to see in greater detail how analogue black holes behave and interact with their surroundings.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- More than two-thirds of Chicago kids younger than 6 live in homes with tap water tainted by lead, a new analysis says.There are detectable levels of lead in the drinking water supplied to 68% of young children in the.
Science Daily: Pharmacology News
MARCH 20, 2024
Working in the Horn of Africa, researchers have uncovered evidence showing how early modern humans survived in the wake of the eruption of Toba, one of the largest supervolcanoes in history, some 74,000 years ago. Modern humans dispersed from Africa multiple times, but the event that led to global expansion occurred less than 100,000 years ago. Some researchers hypothesize that dispersals were restricted to 'green corridors' formed during humid intervals when food was abundant and human populati
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- Boys who drink lots of sugary soda and fruit juice could be more likely to develop type 2 diabetes later in life, a new study has found.Each daily 8-ounce serving of sugary drinks during a boy’s childhood is associated.
Science Daily: Pharmacology News
MARCH 20, 2024
Using data from both mice and humans, a research team has found that a cell surface protein that senses odors and chemicals may be responsible for -- and help explain -- male/female differences in mammalian blood pressure.
Perficient: Drug Development
MARCH 20, 2024
In our latest podcast episode, Jim talks with Kristine Swan , the VP of Digital Transformation and IT at Bayer Crop Science , for a conversation that’s as rich and fertile as the soil our future depends on. Kristine brings a personal touch to the digital revolution in agriculture, drawing on her roots on a Missouri farm. With her at the helm, Bayer is not just sowing seeds but also sowing data – data that empowers farmers across the globe to tackle pressing challenges like climate change and sus
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- Nearly 7 million American seniors are living with Alzheimer’s dementia, placing a huge strain on both personal caregivers and the U.S. health care system, according to a new Alzheimer's Association report. The.
Science Daily: Pharmacology News
MARCH 20, 2024
A new study shows the keto diet prevents early memory decline in mice. A molecule in the diet plays a key role in slowing Alzheimer's disease.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2023 — Planting trees and bushes near busy highways helps clear the air of harmful air pollutants from motor vehicles, new research affirms."They provide benefits that go beyond aesthetics," Roby Greenwald, an associate.
sptlabtech
MARCH 20, 2024
In today’s scientific landscape, labs are under immense pressure to reduce costs, shorten timelines, and maximize output, often from limited resources. Lab automation has emerged as an incredibly valuable tool to address these challenges, empowering researchers to streamline processes and accelerate discoveries. By optimizing common laboratory tasks and processes, lab automation continues to demonstrate its value to the life science community.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- About 1 in every 10 U.S. children ages 5 to 17 has been diagnosed with attention deficit hyperactivity disorder (ADHD), according to the latest government statistics.The data from the National Health Interview Survey.
Science Daily: Pharmacology News
MARCH 20, 2024
The first generation of stars transformed the universe. Inside their cores, simple hydrogen and helium fused into a rainbow of elements. When these stars died, they exploded and sent these new elements across the universe. The iron running in your veins and the calcium in your teeth and the sodium powering your thoughts were all born in the heart of a long-dead star.
On Medicine
MARCH 20, 2024
In a recent blog post , I introduced our study developing a smart-sensing sock to detect and prevent diabetic foot ulcers caused by rubbing, and the importance of understanding patient context when designing health devices. We have now spoken with a range of people with diabetic neuropathy, as well as their carers and podiatrists, and asked them if, when, and how, they would use a device like the smart-sensing sock we are designing.
Science Daily: Pharmacology News
MARCH 20, 2024
Dark matter is one of science's greatest mysteries. Although it is believed to make up about 85 percent of the cosmos, scientists know very little about its fundamental nature. Research provides some of the most stringent constraints on the nature of dark matter yet. It also revealed a small hint of a signal that, if real, could be confirmed in the next decade or so.
SCIENMAG: Medicine & Health
MARCH 20, 2024
NEW ORLEANS, March 20, 2024 — The 2023 Nobel Prize in Chemistry was focused on quantum dots — objects so tiny, they’re controlled by the strange and complex rules of quantum physics.
Science Daily: Pharmacology News
MARCH 20, 2024
Motor neurons are the cells the brain uses to command muscles to act. Scientists typically thought of them as simple connections, much like the cables that link computers with their accessories. Now, in fly studies, researchers have discovered that single motor neurons can each direct an insect's body to move in far more complex ways than previously thought.
The Open Targets Blog
MARCH 20, 2024
The latest release of the Platform — 24.03 — is now available at platform.opentargets.org. Key points In addition to our regular data updates: We have included a direction of effect assessment for eight data sources, to show how genetic variation of a target is associated with risk or protection for a trait We have integrated the latest dataset from Project Score , published earlier this year We have doubled the number of safety assessments by integrating pharmacogenetics data that
Science Daily: Pharmacology News
MARCH 20, 2024
Measuring between 3 to 3.5 meters, 16 million years old: Paleontologists have announced the discovery of a new species of freshwater dolphin in the Peruvian Amazon region. Surprisingly, its closest living relatives can be found in the river dolphins of South Asia.
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