Forbes: Drug Truths

MARCH 6, 2024

There is another aspect of this provision of the IRA that is starting to be felt – "the small molecule penalty"

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Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration issued a health advisory Wednesday warning consumers that six brands of ground cinnamon are tainted with lead. The FDA urged folks to throw away and not buy the following brands of.

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FDA Production Drugs 145

Broad Institute

MARCH 6, 2024

Schizophrenia and aging may share a common biological basis By Allessandra DiCorato March 6, 2024 Breadcrumb Home Schizophrenia and aging may share a common biological basis Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues. By Allessandra DiCorato March 6, 2024 Credit: Ricardo Job-Reese, Broad Communications A new study of aging and schizophrenia reveals synchronized gene expression in astr

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Medical Schools RNA Science Research 134

Chemical Biology and Drug Design

MARCH 6, 2024

Computational analysis and in vitro studies corroborated the cytokines (TNF-α, IL-6 and IL-1β) inhibition potential of the new natural molecule polonilignan. Abstract Targeting pro-inflammatory cytokines and their production is found to be of therapeutic benefit for the regulation of inflammation in various chronic autoimmune diseases. Our continued efforts to discover small molecular-weight pro-inflammatory cytokine inhibitors resulted in identifying a novel natural lignan molecule named poloni

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Pharmacokinetics Regulations Disease Production 100

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

ASPET

MARCH 6, 2024

The organic anion transporting polypeptide (OATP) 2B1 (gene name SLCO2B1 ) is an uptake transporter that facilitates cellular accumulation of its substrates. In order to assess the in vivo relevance of the transporter, we applied SLCO2B1 +/+ knock-in and Slco2b1 -/- knock-out rats. A first pharmacological phenotyping with the OATP2B1 substrate-drug atorvastatin revealed reduced hepatic content and increased expression of rCYP3A1 in the humanized animals.

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Protein Expression Pharmacogenetics Treatment Drugs 100

Science Daily: Pharmacology News

MARCH 6, 2024

A new study provides a new comprehensive look at the potential for flooding in a combined 32 cities along the Atlantic, Pacific, and Gulf coasts. It predicts as many as 500,000 people will be affected by flooding alongside 1 in 35 privately owned properties within the next three decades, and it highlights the racial and socioeconomic demographics of those potentially affected.

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Science Daily: Pharmacology News

MARCH 6, 2024

A galaxy that suddenly stopped forming new stars more than 13 billion years ago has been observed by astronomers. Using the James Webb Space Telescope, astronomers have spotted a 'dead' galaxy when the universe was just 700 million years old, the oldest such galaxy ever observed.

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Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Barry Cadden, co-founder of a specialty compounding pharmacy behind a deadly meningitis outbreak in 2012, has been handed a prison sentence of 10 to 15 years in Michigan for involuntary manslaughter.On Tuesday, Cadden.

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Compounding Pharmacies Pharmacy 119

Science Daily: Pharmacology News

MARCH 6, 2024

Researchers have discovered that nanoscale devices harnessing the hydroelectric effect can harvest electricity from the evaporation of fluids with higher ion concentrations than purified water, revealing a vast untapped energy potential.

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Research 106

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Weight-loss drugs like Wegovy and Ozempic can increase a person’s risk of throwing up during surgery while under anesthesia, a new study reports. People are typically asked to fast prior to surgery because general.

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Drugs 116

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Science Daily: Pharmacology News

MARCH 6, 2024

Engineers developed a cathode material for lithium-sulfur (Li-S) batteries that is healable and highly conductive, overcoming longstanding challenges of traditional sulfur cathodes. The advance holds promise for bringing more energy dense and low-cost Li-S batteries closer to market.

Engineering 100

Engineering Marketing 100

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration on Tuesday approved the country's first continuous glucose monitor for type 2 diabetes.The new Dexcom Stelo Glucose Biosensor System, which will be available by summer, is intended.

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FDA Drugs 111

Science Daily: Pharmacology News

MARCH 6, 2024

Bumblebees successfully learned a two-step puzzle box task through social observation. This task was too complex for individual bees to learn on their own. Observing trained demonstrator bees performing the first unrewarded step was crucial for successful social learning. Individual bees failed to solve the puzzle without previous demonstration, despite extensive exposure.

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Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- A vaginal ring that emits the antiviral dapivirine has passed safety trials and could shield vulnerable women against HIV infection during pregnancy, a new trial shows."We now have data on the ring’s safety during all.

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Trials Drugs 85

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drug Patent Watch

MARCH 6, 2024

GELATIN-Free Medicines, 2024 is part of DrugPatentWatch’s deep library of business intelligence on biopharmaceutical drugs. Buy Gelatin-Free Medicines on Amazon This guide is designed to provide information for healthcare providers to… The post GELATIN-Free Medicines: Which Drugs Contain GELATIN? appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs 94

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Americans will not be able to order free at-home COVID tests after Friday, U.S. health officials announced Tuesday.Households across the country have been able to order four free rapid antigen tests.

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Science Daily: Pharmacology News

MARCH 6, 2024

New research finds around a quarter of Labrador retriever dogs face a double-whammy of feeling hungry all the time and burning fewer calories due to a genetic mutation.

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Research 97

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- When it comes to giving at-risk Americans access to the mental health services they need, prevention is far better than detention, new research confirms.However, a majority of the 950 U.S. counties surveyed in the report.

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Research 98

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

MARCH 6, 2024

Physicists are developing a method that could enable the stable exchange of information in quantum computers. In the leading role: photons that make quantum bits 'fly'.

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Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- There's more evidence bolstering the health effects of both breastfeeding and the COVID booster shot: Vaccinated, breastfeeding moms appear to pass COVID-fighting antibodies to their infants. That's important, since.

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Vaccine 98

SCIENMAG: Medicine & Health

MARCH 6, 2024

A team from Nagoya University in Japan has identified previously unidentified gene variants that are associated with the development of generalized pustular psoriasis (GPP). The team’s findings, published in the Journal of the American Academy of Dermatology, offer hope for improving diagnosis and therapy.

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Disease Therapies 88

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Folks who've suffered a concussion and then develop headaches show iron accumulation in their brains, new research discovers.Excess brain iron stores are a hallmark of damage, noted a team led by Simona Nikolova, of the.

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Research 98

SCIENMAG: Medicine & Health

MARCH 6, 2024

In a potentially game-changing development, scientists with the Fralin Biomedical Research Institute at VTC have revealed a new understanding of sometimes fatal viral infections that affect the heart.

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Research 84

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Air pollution harms the health of everyone exposed to it, but a new study says communities of color are disproportionately harmed by dirty air.Smog causes nearly 8 times higher childhood asthma rates and 1.3 times higher.

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SCIENMAG: Medicine & Health

MARCH 6, 2024

SWANSEA UNIVERSITY NEWS RELEASE Credit: Swansea University SWANSEA UNIVERSITY NEWS RELEASE 06 March 2024 Impact of COVID on people with epilepsy: higher rate of deaths and hospitalisations, new research shows People with epilepsy had a higher risk of being hospitalised with COVID and of dying from COVID during the first 15 months of […]

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Hospitals Research 82

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Menopause is thought to trigger mood changes among women, with changes in female hormone levels contributing to anxiety, depression and stress.However, a new study says some women are at more risk than others for.

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SCIENMAG: Medicine & Health

MARCH 6, 2024

Higher BMI is significantly associated with worse mental health, especially in women, per study of middle-aged and older adults which adjusted for lifestyle and demographic factors Credit: Teona Smith, Pexels, CC0 ([link] Higher BMI is significantly associated with worse mental health, especially in women, per study of middle-aged and older adults which adjusted for lifestyle […]

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BioPharma Drive: Drug Pricing

MARCH 6, 2024

Study results showed early signs of promise in Duchenne patients who are currently ineligible to receive Sarepta’s Elevidys, triggering a stock surge.

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Therapies 88

Science Daily: Pharmacology News

MARCH 6, 2024

It would be a game-changer if all members of a basketball team could see out of each other's eyes in addition to their own. Biologists have found evidence that this kind of collective sensing occurs in close-knit groups of African weakly electric fish, also known as elephantnose fish. This instantaneous sharing of sensory intelligence could help the fish locate food, friends and foes.

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SCIENMAG: Medicine & Health

MARCH 6, 2024

An injectable hydrogel can mitigate damage to the right ventricle of the heart with chronic pressure overload, according to a new study published March 6 in Journal of the American College of Cardiology: Basic to Translational Science.

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Science 73

Covalent Modifiers

MARCH 6, 2024

Qinheng Zheng, Ziyang Zhang, Keelan Z. Guiley & Kevan M. Shokat Nat Chem Biol 2024 [link] K-Ras is the most commonly mutated oncogene in human cancer. The recently approved non-small cell lung cancer drugs sotorasib and adagrasib covalently capture an acquired cysteine in K-Ras-G12C mutation and lock it in a signaling-incompetent state. However, covalent inhibition of G12D, the most frequent K-Ras mutation particularly prevalent in pancreatic ductal adenocarcinoma, has remained elusive due t

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Drugs 71

BioPharma Drive: Drug Pricing

MARCH 6, 2024

Incubated by RA Capital and backed by a wide array of investors, the startup is developing drugs that work differently than Vertex’s market-leading medicines.

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Marketing Drugs 75

Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- Childhood exposure to lead has long been a public health concern, with lead in water and paint leading to brain damage and developmental delays in kids.Now researchers have uncovered an unexpected source of household.

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Research 75