Drug Discovery World
NOVEMBER 30, 2023
The Food and Drug Administration (FDA) said it will investigate the safety of BCMA- or CD19-directed autologous CAR-T cell immunotherapies, following reports of T cell malignancies, including chimeric antigen receptor CAR-positive lymphoma, in these patients. The reports were received from clinical trials and postmarketing adverse event (AE) data sources.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Scientists have created tiny moving biological robots from human tracheal cells that can encourage the growth of neurons across artificial 'wounds' in the lab. Using patients' own cells could permit growth of Anthrobots that assist healing and regeneration in the future with no nead for immune suppression.
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Drug Discovery World
NOVEMBER 30, 2023
Biotechnology company Certa Therapeutics has revealed positive Phase II clinical trial data for FT011 in patients with scleroderma. The results were presented at ACR Convergence 2023, the annual scientific meeting of the American College of Rheumatology in San Diego, California (10-15 November 2023). Treatment with FT011 for 12 weeks resulted in a clinically meaningful improvement in 60% of patients treated with FT011 400mg and 20% of patients in the FT011 200mg group compared with 10% in the pl
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
NOVEMBER 30, 2023
This is the latest episode of the free DDW narrated podcast, “Outside the box thinking for drug discovery success”, which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Stanford researchers construct the most complete synthetic microbiome , Highs and lows of drug repurposing , and Unlocking the potential of mucoadhesive drug delivery.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 -- Migraine sufferers would do better to talk to their doctor about a prescription drug than reaching for a bottle of ibuprofen, a new study finds.Drugs like triptans, ergots and anti-emetics can be two to five times more.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Antidote
NOVEMBER 30, 2023
Despite the fact that colorectal cancer cases have been declining in the United States since the mid-1980s, it is still the third most common cancer diagnosed each year excluding skin cancer. Often shortened to colon cancer, colorectal cancer occurs when cells in the colon and/or the rectum begin to grow uncontrollably and eventually spread to other parts of the body.
Drug Discovery World
NOVEMBER 30, 2023
Keep up to speed with the sector’s top executive appointments with DDW’s regular recruitment round-up. Kimryn Rathmell has been chosen as the 17 th director of the National Cancer Institute (NCI), bringing her experience as leader of the Department of Medicine at the Vanderbilt University Medical Center and Physician-in-Chief at the Vanderbilt University Adult Hospital and Clinics.
LifeSciVC
NOVEMBER 30, 2023
After the bursting of the pandemic biotech bubble, talk of industry consolidation was ubiquitous. The sector had pushed out too many IPOs during the go-go years, leading to too many public biotech companies, with sub-scale enterprises, and wasteful crowding in lots of therapeutic categories. And too many inexperienced management teams leading those newly-minted public companies.
Drug Discovery World
NOVEMBER 30, 2023
This is the latest episode of the free DDW narrated podcast, “Outside the box thinking for drug discovery success”, which covers three written for Volume 23 – Issue 4, Fall 2022 of DDW. They are called: Stanford researchers construct the most complete synthetic microbiome , Highs and lows of drug repurposing , and Unlocking the potential of mucoadhesive drug delivery.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 -- Tinnitus, or "ringing in the ears," affects up to 1 in every 10 people and can be disabling for some.Now, scientists at the Massachusetts Ear and Eye Infirmary believe they may have discovered a key cause of the.
PPD
NOVEMBER 30, 2023
As we approach the end of 2023, it’s time to reflect on the past 12 months and how advances in drug development shaped the pharma and biotech industries. These shifts are a prelude to further change and progress in the clinical trial landscape in 2024. This year, the U.S. Food and Drug Administration (FDA) has approved 47 new molecular entities for therapeutic use, already exceeding last year’s progress, which yielded 37 novel drug approvals.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 (Healthday News) -- The U.S. Environmental Protection Agency announced Thursday that it plans to require the removal of all lead pipes from the country's water systems.The proposed rule, an ambitious effort that will cost up.
Drug Channels
NOVEMBER 30, 2023
Today’s guest post comes from Josh Bliss, Head of Pharma Solutions at SingleCare. Josh outlines manufacturers’ challenge when educating and informing patients about patient support programs. He then describes the SingleCare prescription discount card and Pharma Solutions , which provides manufacturers with a platform to reach patients. Click here to learn how manufacturers can advertise patient support programs at the point of purchase.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 -- A woman who gets her regular mammograms as scheduled is much less likely to die from breast cancer than if she skips screenings, a new study shows.Women with breast cancer who underwent all her scheduled mammograms had a.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney stone prevention because they reduce the excretion of urinary calcium.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 -- Elevated levels of thyroid hormone appear to harm the aging brain, increasing seniors’ risk of dementia or other cognitive disorders, a new study finds.High levels of thyroid hormone -- a condition called thyrotoxicosis.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
The American College of Cardiology (ACC) and the American Heart Association (AHA), along with several other leading medical associations, have issued a new guideline for preventing and optimally managing atrial fibrillation (AFib). The guideline was jointly published today in the Journal of the American College of Cardiology and Circulation.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 (Healthday News) -- Parents should worry less about whether their young child could catch COVID while in daycare, and worry more about them being infected at home once a family member falls ill, new research suggests. In.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Researchers have discovered that the waxy protective barrier around plants might play a role in sending chemical signals to other plants and insects.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
Across the 30 countries of the European Union and European Economic Area (EU/EEA), 22,995 new HIV diagnoses were reported in 2022. Almost every second new HIV diagnosis (49%, n=11,103) was among migrants, i.e. among people who were not born in in the country they were diagnosed in. born abroad from the country of their diagnosis.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Melting of glaciers, rising sea levels, extreme heat waves: the consequences of climate change are more visible than ever, and the scientific community has confirmed that humans are responsible. Yet studies show that a third of the population still doubts or disputes these facts. The cause is disinformation spread by certain vested interests. To try and prevent this phenomenon, a team has developed and tested six psychological interventions on nearly 7,000 participants from twelve countries.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
Dr. Odette Tomescu-Hatto has been appointed Executive Vice-President, International Affairs at the Institut Pasteur, with effect from January 2024. Credit: © Institut Pasteur – François Gardy Dr. Odette Tomescu-Hatto has been appointed Executive Vice-President, International Affairs at the Institut Pasteur, with effect from January 2024.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Found in fishing nets, carpet, clothing, Nylon-6 is a major contributor to plastic pollution, including ocean pollution. Now, chemists have developed a new catalyst that quickly, cleanly and completely breaks down Nylon-6 in a matter of minutes -- without generating harmful byproducts. Even better: The process does not require toxic solvents, expensive materials or extreme conditions, making it practical for everyday applications.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
Boston – George Demetri, MD, director of the Sarcoma Center at Dana-Farber Cancer Institute, is being awarded the prestigious J.E. Wallace Sterling Lifetime Achievement Award in Medicine from the Stanford Medicine Alumni Association (SMAA).
Science Daily: Pharmacology News
NOVEMBER 30, 2023
The discovery of a planet that is far too massive for its sun is calling into question what was previously understood about the formation of planets and their solar systems.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
BOSTON – Individuals can improve their brain care and reduce their risk of developing brain diseases such as dementia and stroke by focusing on a list of 12 steps covering modifiable physical, lifestyle, and social-emotional components of health.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
A recent trial of identical twins comparing vegan and omnivore diets found that a vegan diet improves overall cardiovascular health.
SCIENMAG: Medicine & Health
NOVEMBER 30, 2023
As part of its ongoing quest to advance better brain health and performance, new research led by Center for BrainHealth at The University of Texas at Dallas investigated neural biomarkers associated with improvements on a brain health index.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Farmland often harbors a multitude of pathogens which attack plants and reduce yields. A research team has now shown that inoculating the soil with mycorrhizal fungi can help maintain or even improve yields without the use of additional fertilizers or pesticides. In a large-scale field trial, plant yield increased by up to 40 percent.
PLOS: DNA Science
NOVEMBER 30, 2023
Anyone who lives with more than one member of Felis catus knows that our beloved felines love to smell each other’s anal regions. Now a research team from the Department of Evolution and Ecology and Genome Center University of California, Davis, explains why, with their cataloging of the microbiomes of domestic cat anal glands. The bacterial members of the microbiome produce and release organic compounds that affect the behavior of another cat.
Drugs.com
NOVEMBER 30, 2023
THURSDAY, Nov. 30, 2023 -- The latest national data show that when it comes to suicide, Americans are increasingly resorting to firearms as their method of choice. An analysis by researchers at the U.S. Centers for Disease Control and.
Science Daily: Pharmacology News
NOVEMBER 30, 2023
Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.
sptlabtech
NOVEMBER 30, 2023
Recognizing that laboratories have diverse requirements, we believe in abandoning a one-size-fits-all approach when it comes to tube handling. As an integral part of your research, tube handling systems must be able to address your specific needs to deliver maximum value. With our BioMicroLab XL systems , not only can you select a base unit depending on your rack capacity needs, but you have the freedom to add on modules that provide the exact functionality you need.
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