Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Clostridioides difficile (C. difficile) is a leading cause of illness and death, especially for frail and hospitalized Americans. Now, a new study suggests that the leading antibiotic used to fight it, vancomycin, may be.
Science Daily: Pharmacology News
APRIL 26, 2024
Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high. In a recent study, researchers tested a novel approach that involves injecting 'cardiac spheroids,' cultured from human stem cells, directly into damaged ventricles.
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BioPharma Drive: Drug Pricing
APRIL 26, 2024
The Food and Drug Administration approval of Beqvez comes as other gene therapies for the bleeding condition that were approved earlier struggle to gain traction.
Science Daily: Pharmacology News
APRIL 26, 2024
Are mice clever enough to be strategic? A neuroscientist who studies learning in humans and animals, and who has long worked with mice, wondered why rodents often performed poorly in tests when they knew how to perform well. With a simple experiment, and by acting as 'a little bit of a mouse psychologist,' he and his team figured it out.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drugs.com
APRIL 26, 2024
FRIDAY, April 25, 2024 -- Warning letters sent by Medicare officials can prompt a decline in antipsychotic prescriptions for seniors with dementia, a new study finds.Letters sent to heavy prescribers of quetiapine (Seroquel), the most popular.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Each year, thousands of Americans head home after a surgery clutching prescription opioids to help ease post-surgical pain.
Science Daily: Pharmacology News
APRIL 26, 2024
Using environmental DNA analysis, an international team of researchers identified a collection of plants used in ceremonial rituals in the ancient Maya city of Yaxnohcah in Mexico. The plants, known for their religious associations and medicinal properties, were discovered beneath a plaza floor where a ballcourt was built.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 (HealthDay) -- Between 2018 and the spring of 2023, a cluster of clients who had gotten 'vampire facial' microneedling skin treatments at a New Mexico spa were diagnosed with HIV, probably via poorly cleaned instruments, a new.
Collaborative Drug
APRIL 26, 2024
New Interface for Protocol Readout Definitions We are excited to announce a new, modern GUI for creating Protocol readout definitions in CDD Vault. This update provides a more intuitive and flexible approach to managing your data, especially for handling dose-response calculations essential for the upcoming Curve Analytics module. Key Features: Modular Approach to Readout Definitions: Dose-Response:: Users must define their concentration and raw data values independently.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- The emotional turmoil caused by a stolen dog is akin to that of a parent losing a child, a new study finds.The findings support the idea that pets truly become family members to their owners, researchers said. When faced.
Science Daily: Pharmacology News
APRIL 26, 2024
Researchers co-led a study that will improve the detection of gravitational waves--ripples in space and time.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Bits of bird flu virus have been discovered in roughly 20% of retail milk samples tested in a national survey, the U.S. Food and Drug Administration said Thursday.The finding suggests that bird flu has spread far more.
BioPharma Drive: Drug Pricing
APRIL 26, 2024
Prescription volume erosion is tracking with company forecasts, executives claimed, even as more insurers could exclude the branded drug.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Most seniors probably view any emergency surgery with a certain level of anxiety. Now, a new study seeks to sort out who might be at highest risk for a complication from such surgeries -- and which surgeries are more.
LifeSciVC
APRIL 26, 2024
Venture creation in biotech is witnessing a sustained contraction. After the pandemic bubble’s over-indulgence, the venture ecosystem appears to have reset its pace of launching new startups. According to the latest Pitchbook data, venture creation in biotech hit its slowest quarterly pace in eight years during 1Q 2024. With just over 60 new biotechs raising their first round of financing, the sector’s company formation activity has slowed 50-60% from its historic peak in 2021.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Better heart health can lead to a sharper mind for middle-aged Black women, a new study says.
NIOSH Science Blog: Drugs
APRIL 26, 2024
Each year, on April 28, we pause to recognize Workers’ Memorial Day and honor those whose death or suffering resulted from exposure to hazards at work. Words are not enough when it comes to change. Research has shown that the health and safety of workers relies on active and intentional involvement in ways that take into consideration workplace hazards, work arrangements and environment, employer-worker relationships, the workers themselves, and their families.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- The U.S. Department of Agriculture is clamping down on salmonella bacteria found in breaded, stuffed raw chicken products, with the agency issuing a final rule on the issue Friday.The agency's Food Safety and Inspection.
ASPET
APRIL 26, 2024
Recent studies suggest that amongst the GABA A receptor subtype heterogeneity, α2/α3 subunits of GABA A receptors mediate pain processing. Therefore, α2/α3-subtype selective GABA A receptor positive allosteric modulators (PAMs) may be candidate analgesics. Antinociceptive effects of α2/α3-subtype selective GABA A receptor PAMs have been reported, but the behavioral effects of these compounds have not been systematically evaluated.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Advanced scanning techniques can find hidden inflammation in the brains of multiple sclerosis (MS) patients, a new study shows.This “smoldering” inflammation detected by positron emission tomography (PET) brain scans.
ASPET
APRIL 26, 2024
Dotinurad was developed as a uricosuric agent, inhibiting urate (UA) reabsorption through the UA transporter URAT1 in the kidneys. Due to its high selectivity for URAT1 among renal UA transporters, we investigated the mechanism underlying this selectivity by identifying dotinurad binding sites specific to URAT1. Dotinurad was docked to URAT1 using AutoDock4, utilizing the AlphaFold2-predicted structure.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
APRIL 26, 2024
FRIDAY, April 25, 2024 -- Cancer survivors in the throes of loneliness are more likely to die compared to those with companionship, a new study finds.Further, people who are the most lonely are the most likely to die, results show.
ASPET
APRIL 26, 2024
Histone deacetylase expression and activity are often dysregulated in central nervous system (CNS) tumors, providing a rationale for investigating histone deacetylase inhibitors (HDACIs) in selected brain tumor patients. Although many HDACIs have shown potential in in vitro studies, they have had modest efficacy in vivo. This lack of activity could be due to insufficient CNS exposure to the unbound drug.
Drugs.com
APRIL 26, 2024
FRIDAY, April 26, 2024 -- Want to live longer? Choose the stairs over the elevator, a new review suggests.Folks who regularly climb stairs have a 24% reduced risk of dying from any cause, and a 39% reduced risk of dying from heart disease, compared.
Drug Channels
APRIL 26, 2024
Today’s guest post comes from Kevin Kettler, President of CoverMyMeds. Kevin asks: What if there were no barriers across the therapy access and reimbursement process? In his view, eliminating barriers requires a combination of expert insight, actionable data, and simplification of the providers' experiences. Click here to learn more about CoverMyMeds’ comprehensive technology solutions.
Cytel
APRIL 26, 2024
Written by Marie Diamond and Maria Rizzo Systematic literature reviews (SLR) are essential to informing healthcare decision-making and are pivotal for reimbursement submissions to health technology assessment (HTA) bodies. One limitation of SLRs, however, is that they quickly become outdated due to the continuous publication of new literature. The living systematic review (LSR) model can overcome this challenge by incorporating relevant new evidence as it is published.
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