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Seeds, twigs, and insect parts found under two miles of ice confirm Greenland's ice sheet melted in the recent past, the first direct evidence that the center -- not just the edges -- of the two-mile-deep ice melted away in the recent geological past. The new research indicates that the giant ice sheet is more fragile than scientists had realized until the last few years -- and reveals increased risk of sea-level catastrophe in a warmer future.
MONDAY, Aug. 5, 2024 -- Botanicals like turmeric, green tea and black cohosh may seem benign, but their overuse is being increasingly linked to liver injury. New research suggests that 7% of U.S. adults are using at least one of the six leading.
Scientists from across academic disciplines are extremely concerned about climate change. Many of them have already changed their own lifestyles or engaged in advocacy and protest, with even more being willing to do so in future. This is evident from a large-scale survey of scientists from all over the world.
MONDAY, Aug. 5, 2024 (HeathDay News) -- A new antimicrobial compound can effectively clear “flesh-eating” bacterial infections in mice, a new study shows.The compound could be the first in an entirely new class of antibiotics, which could prove inv.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.
MONDAY, Aug 5, 2024 -- Millions of Americans use the opioid-like herbal supplement known as kratom, but evidence of its dangers continue to mount.The U.S. Food and Drug Administration has issued another alert for consumers to stay away from one.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
MONDAY, Aug 5, 2024 -- Millions of Americans use the opioid-like herbal supplement known as kratom, but evidence of its dangers continue to mount.The U.S. Food and Drug Administration has issued another alert for consumers to stay away from one.
For years, many manufacturers have assumed that pre-market physician education was not strictly necessary unless their brand was the first to market or had a novel mechanism of action. With the advent of precision medicine, however, ongoing disease state education has become increasingly critical.
If somebody complains that it hurts to think, they may be onto something, as mental exertion appears to be associated with unpleasant feelings in many situations, according to new research.
MONDAY, Aug. 5, 2024 -- Three out of four police officers have experienced at least one concussion, increasing their risk of mental health issues, a new study suggests. About 74% of Ohio law enforcement officers had suffered one or more head.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
New findings on how sharks achieve drag reduction could inspire the design of riblets for more efficient aircraft and boats. In their investigation of great white shark denticles, researchers found that ridge height and spacing play crucial roles in drag reduction at different swimming speeds. Higher middle ridges aid sharks in efficient cruising at slower speeds, while the lower side ridges become more critical for drag reduction during high-speed hunting bursts.
MONDAY, Aug 5, 2024 -- Folks worried about bird flu, salmonella and other foodborne illnesses have a simple solution at hand – simply use a cooking thermometer to make sure food is well-cooked.But only about 1 in 4 Americans (27%) use one either “.
A groundbreaking study has revealed that red dwarf stars can produce stellar flares that carry far-ultraviolet (far-UV) radiation levels much higher than previously believed.
MONDAY, Aug. 5, 2024 -- Many people with disabilities aren’t getting the exercise they need because fitness centers don’t offer adaptive equipment or staff trained in helping the disabled, a new review finds.There are few efforts by most commercial.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
The Pyramid of Djoser, the oldest of Egypt's iconic pyramids, may have been built with the help of a unique hydraulic lift system, according to researchers. A new study suggests that water may have been able to flow into two shafts located inside the pyramid itself, where that water could have been used to help raise and lower a float used to carry the building stones.
MONDAY, Aug. 5, 2024 -- Women who use a breast pump to store milk for their infant tend to breastfeed 21 weeks longer, on average, compared to moms who don't use the devices, new research finds.Breast pumps have gained wide use among busy new moms.
Understanding neutrino interactions is crucial for obtaining a complete picture of particle physics and the universe. To date, neutrino interaction cross sections have not been measured at high energy above some hundred gigaelectronvolts at particle colliders. Now, researchers have obtained the first direct observation of electron and muon neutrino interactions in the Teraelectronvolt range at CERN's Large Hadron Collider, using the FASER detector.
MONDAY, Aug. 5, 2024 -- The U.S. heart transplant list for children isn’t accurately ranking the sickest kids highest, making it more likely they may die while waiting for a donor heart, a new study claims. Some very sick children were.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Scientists have developed a new bioactive material that successfully regenerated high-quality cartilage in the knee joints of a large-animal model. New material comprises peptides, proteins and polysaccharides that mimic the microstructure of natural cartilage. Within six months, researchers observed new cartilage growth.
MONDAY, Aug. 5, 2024 -- Folks who rub their forehead and complain that a complex problem is making their brain hurt aren’t overstating things, a new review suggests.Mental exertion appears to be associated with unpleasant feelings in many s.
Thatikonda, V., Lyu, H., Jurado, S. et al. Nat Cancer (2024). [link] Combination approaches are needed to strengthen and extend the clinical response to KRASG12C inhibitors (KRASG12Ci). Here, we assessed the antitumor responses of KRASG12C mutant lung and colorectal cancer models to combination treatment with a SOS1 inhibitor (SOS1i), BI-3406, plus the KRASG12C inhibitor, adagrasib.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
MONDAY, Aug. 5, 2024 -- Depression can lower a woman’s chances of surviving breast cancer, a new study reports.Women with breast cancer and depression are more than three times as likely to die as women without either condition, researchers f.
The decision makes Bristol the latest pharma to pull back on research into a type of cancer immunotherapy that’s drawn significant investment in recent years.
Proinflammatory cytokines, elevated during inflammation caused by infection and/or autoimmune disorders, result in reduced clearance of drugs eliminated primarily by cytochrome P450 enzymes (CYPs). However, the effect of cytokines on hepatic drug transporter expression or activity has not been well-studied. Here, using plated human hepatocytes (PHHs; n=3 lots), we investigated the effect of interleukin (IL)-6, IL-1β, tumor necrosis factor-α (TNF-α), and interferon- (IFN-), on the
Pulmonary arterial hypertension (PAH) is a progressive and fatal lung disease that is caused or influenced by multiple factors. Historically, the available drugs and U.S. Food and Drug Administration (FDA)-approved therapies for treating PAH were primarily vasodilators, designed to overcome the imbalance between vasoactive and vasodilator mediators and to restore endothelial cell function.
Cannabinoid and opioid receptor activities can be modulated by a variety of posttranslational mechanisms including the formation of interacting complexes. This study examines the involvement of endogenous and exogenous chaperones in modulating the abundance and activity of cannabinoid CB 1 receptor (CB 1 R), delta opioid receptor (DOR), and CB 1 R-DOR interacting complexes.
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