Mon.Sep 16, 2024

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Researchers test ChatGPT, other AI models against real-world students

Science Daily: Pharmacology News

An experiment tested six generative large language models against students in an online introductory biomedical and health informatics course. The models scored higher than as many as three quarters of the real-world students in the class.

Research 313
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Polluting Puff: Asthma Inhalers Are Big Contributors to Climate Change

Drugs.com

MONDAY, Sept. 16, 2024 -- Tiny puffs from asthma inhalers could be causing big climate problems for Mother Earth, a new study warns.Each inhaler dose contains some of the most potent greenhouse gases known, and they are adding up, researchers.

Research 299
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How the brain changes during pregnancy

Science Daily: Pharmacology News

Researchers follow the dramatic changes that occur in the brain throughout the course of pregnancy.

Research 297
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Ozempic Could Curb Progression of Diabetes-Linked Liver Disease

Drugs.com

MONDAY, Sept. 16, 2024 -- Fatty liver disease linked to diabetes and obesity can easily progress to liver cirrhosis, but new research suggests that GLP-1 medicines like Ozempic can help stop that. In a new decades-long study, veterans with diabetes.

Disease 299
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Genomics reveals sled dogs' Siberian lineage

Science Daily: Pharmacology News

New research examines thousands of years of Arctic sled dog ancestry and reveals when and how Siberian and Alaskan sled dogs' DNA mixed.

DNA 294

More Trending

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Astronomers detect black hole 'starving' its host galaxy to death

Science Daily: Pharmacology News

Astronomers have used the NASA/ESA James Webb Space Telescope to confirm that supermassive black holes can starve their host galaxies of the fuel they need to form new stars.

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Breathing Could Bring Microplastics Into the Human Brain, Study Shows

Drugs.com

MONDAY, Sept. 16, 2024 -- For the first time, scientists have detected microscopic microplastics lodged in the human brain.Researchers in Germany and Brazil say that 8 out of 15 autopsied adults had microplastics detected within their brain's smell.

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'Food theft' among seabirds could be transmission point for deadly avian flu

Science Daily: Pharmacology News

If seabirds can catch avian flu by stealing food from infectious birds, it gives scientists a clue where to monitor for outbreaks among these vulnerable birds.

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Vaping Is Harming College Students' Brains, Study Shows

Drugs.com

MONDAY, Sept. 16, 2024 -- Vaping may look cool when you're young, but it appears to be dulling the brains of college students, a new study warns.College students who vape have lower cognitive function scores than those who don't, researchers.

Research 278
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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As Biosecure bill advances, drugmakers prepare for prospect of China pivot

BioPharma Drive: Drug Pricing

Legislation that passed the House of Representatives passed the Biosecure Act last week would forced U.S. biotechs to cut ties with five Chinese contract partners.

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Missouri Bird Flu Case Raises Possibility of Human Transmission

Drugs.com

MONDAY, Sept. 16, 2024 (Healthday News) -- In a disclosure that can't eliminate the possibility that bird flu may have spread from one human to another for the first time, U.S. health officials have reported that a person who lived with a Missouri.

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Bridging science and humanity: How systems thinking should shape clinical trial execution

BioPharma Drive: Drug Pricing

Applying a systems thinking approach can create improvements in scientific integrity, operational feasibility and scalability.

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Immunotherapy Drugs Extend Survival for Patients With Advanced Melanomas

Drugs.com

MONDAY, Sept 16, 2024 -- A decade of patient follow-up finds a combo of two immunotherapy drugs can greatly extend survival for people with advanced melanomas.In 2011, a diagnosis of advanced, metastatic melanoma typically meant death within 6.5.

Drugs 264
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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ESMO24: A cancer cachexia drug, VEGF enthusiasm and immunotherapy’s survival impact

BioPharma Drive: Drug Pricing

Results for Pfizer’s ponsegromab looked promising, while BioNTech and Instil Bio capitalized on momentum surrounding a kind of bispecific antibody.

Drugs 209
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Genetics Suggest Link Between ALS, Parkinson's Disease

Drugs.com

MONDAY, Sept. 16, 2024 -- People with rare genetic variants linked to degenerative brain disorders like Parkinson’s disease are at increased risk of developing ALS, a new study finds.Further, having these genetic variants increases the risk of a p.

Disease 246
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Evaluating the potential for psilocybin as a treatment for post-traumatic stress disorder [Minireview]

ASPET

Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition that develops following exposure to a traumatic event. Individuals with this condition experience numerous physiological and behavioral alterations, including intrusive memories, avoidance of trauma-related stimuli, heightened anxiety, hypervigilance, impaired cognition, elevated resting heart rate and blood pressure, and altered neuroendocrine function, to name a few.

Treatment 189
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One Part of Football Helmets Especially Linked to Concussion

Drugs.com

MONDAY, Sept. 16, 2024 -- Newfangled designs intended to make football helmets more protective have overlooked one key component, a new study suggests.Nearly a third of concussions in pro football involve impacts to the facemask, a part of the.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Generative AI can enhance pharmaceutical innovation – but are you ready for it?

BioPharma Drive: Drug Pricing

There’s no doubt that AI and GenAI can speed up pharmaceutical innovation. But before organizations can jump into the future, it’s crucial to understand the benefits – and the risks – of advanced technology.

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Pregnancy Changes the Brain, Study Finds

Drugs.com

MONDAY, Sept. 16, 2024 -- With implications for research around postpartum depression and other health issues, scientists have tracked the changes pregnancy brings to the female brain. These changes weren't subtle: Big shifts in what's known as the.

Research 130
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Kyverna swaps CEOs, leaning on Kite veterans to lead ‘next chapter’

BioPharma Drive: Drug Pricing

Warner Biddle and Christi Shaw, two prominent former executives at Gilead’s CAR-T division, will try to turn around an autoimmune cell therapy developer that’s lost most of its value since raising $319 million in a February IPO.

Therapies 166
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Poll Finds Many Parents Worry About Kids Finding Friends

Drugs.com

MONDAY, Sept. 16, 2024 -- Many parents worry that their kids aren’t popular enough, or that they aren’t making the right friends, a new survey finds.About 1 in 5 parents say their child aged 6 to 12 has no friends or not enough friends, according to.

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Sanofi readies to meet US demand for RSV antibody

BioPharma Drive: Drug Pricing

With a new production line, Sanofi aims to keep it and partner AstraZeneca’s drug Beyfortus in fully supply this RSV season.

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How is Parkinson’s disease diagnosed?

Antidote

Receiving a Parkinson’s diagnosis is a life-altering event that nearly 1 million people in the United States have experienced. Parkinson’s disease symptoms can vary from person to person. Receiving a diagnosis often requires several steps. In this blog, we’ll be sharing more details about the disease and discussing opportunities for individuals to get involved in Parkinson’s research.

Disease 114
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Easy GxP compliance for NGS data – is it even possible?

BioPharma Drive: Drug Pricing

NGS is changing the landscape for GxP compliance. How can you adapt?

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Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells

Chemical Biology and Drug Design

This study identified MAPK9 as the directly binding target of baicalein by the DNA-programmed affinity labeling method and tested the binding affinity as 89.7 nM by surface plasmon resonance. Baicalein stabilized MAPK9 to induce apoptosis in hepatocarcinoma cells, which would be helpful to understand and use baicalein in hepatocarcinoma therapy. ABSTRACT Hepatocellular carcinoma (HCC) is a significant global health concern.

DNA 100
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Accelerating the new wave of CAR T therapy trials

BioPharma Drive: Drug Pricing

Applying CAR T-cell therapy in new clinical settings presents unique challenges. Worldwide Clinical Trials is at the forefront, partnering with drug development teams to map this new path forward.

Therapies 130
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Alternative reinforcers enhance the effects of opioid antagonists, but not agonists, on oxycodone choice self-administration in nonhuman primates [Behavioral Pharmacology]

ASPET

Clinical reports suggest that the most effective strategies for managing opioid use disorder comprise a comprehensive treatment program of both pharmacological and non-pharmacological approaches. However, the conditions under which these combinations are most effective are not well characterized. This study examined whether the presence of an alternative reinforcer could alter the efficacy of FDA-approved opioid antagonist or agonist medications, as well as the non-opioid flumazenil, in decreasi