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Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The breakthrough science focused on replicating heart tissues, bringing research closer to generating functional, bioprinted organs, which would have broad applications in disease modelling, drug screening and regenerative medicine.
WEDNESDAY, Jan. 22, 2025 -- Medicare will soon negotiate prices for 15 more drugs as part of an effort to reduce costs for seniors and people with disabilities, federal health officials announced in a news release. The negotiations, made possible.
Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Now, researchers have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.
WEDNESDAY, Jan. 22, 2025 -- The U.S. Food and Drug Administration has approved Spravato (esketamine) CIII nasal spray for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win. At first, a brain chemical called dopamine is essential for young males to master this behavior. But as they gain experience, the chemical grows less important in promoting aggression, a new study shows.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates. The rising incidence of these infections, coupled with increasing antifungal resistance, underscores the urgent need for novel therapeutic strategies.
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The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates. The rising incidence of these infections, coupled with increasing antifungal resistance, underscores the urgent need for novel therapeutic strategies.
Researchers evaluated a drug that represents a new class of anticoagulants known as Factor XI inhibitors for treating patients with atrial fibrillation as part of the AZALEA-TIMI 71 Study. The trial was stopped early by the recommendation of the Data Monitoring Committee due to an overwhelming reduction in bleeding compared to standard-of-care treatment.
WEDNESDAY, Jan. 22, 2025 -- A sudden need to urinate is more common than previously known, but treatment is less common.Diagnoses for overactive bladder more than tripled between 2013 and 2017, after the American Urological Association (AUA).
Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.
WEDNESDAY, Jan. 22, 2025 -- Could eating more fiber be the key to a healthier gut? Research suggests the answer is yes. The findings, published recently in the journal Nature Microbiology, analyzed gut microbiomes from more than 12,000 people in 45.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Successful uptake of new technology is a matter of emotions -- and with 4 in 5 companies saying they're failing to capitalize on its potential, managers need to know how to deal with them, say researchers.
WEDNESDAY, Jan. 22, 2025 -- A set of chameleon-like immune cells could be contributing to severe asthma in some patients.Intermediate group 2 innate lymphoid cells (ILC2s) appear to be able to get around cutting-edge asthma treatments by.
WEDNESDAY, Jan. 22, 2025 -- Want your kid to do well in school?Get them involved in an organized sport, a new study urges.Boys and girls are both more likely to earn a high school diploma if they take part in team sports like soccer or artistic.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Researchers have identified a new class of quantum states in a custom-engineered graphene structure. The study reports the discovery of topological electronic crystals in twisted bilayer -- trilayer graphene, a system created by introducing a precise rotational twist between stacked two-dimensional materials.
WEDNESDAY, Jan. 22, 2025 -- Rural areas are facing an increasing shortage of eye surgeons who can treat conditions like cataracts, glaucoma and detached retinas, a new study says.More than 17% of patients who need an ophthalmic surgeon live in.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Deeply hidden in Earth's mantle there are two huge 'islands' with the size of a continent. New research shows that these regions are not only hotter than the surrounding graveyard of cold sunken tectonic plates, but also that they must be ancient: at least half a billion years old, perhaps even older. These observations contradict the idea of a well-mixed and fast flowing Earth's mantle, a theory that is becoming more and more questioned.
Scientists have completed construction of the final chromosome in the worlds' first synthetic yeast genome following more than a decade of work, opening new possibilities for creating resilient, engineered organisms.
The biotech said it has dosed the first participant in a Phase 3 study of its in vivo gene editing treatment. Elsewhere, the FDA imposed a hold on Atara and lifted another on Amylyx.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
A new study has used a modelling approach to show that it is unlikely that plants would evolve to warn other plants of impending attack. Instead of using their communication networks to transmit warning signals, the findings suggest it is more likely that plants 'eavesdrop' on their neighbors.
For 2025, the three largest pharmacy benefit managers (PBMs)Caremark (CVS Health), Express Scripts (Cigna), and Optum Rx (United Health Group)have again each excluded hundreds of drugs from their standard formularies. You can find our updated counting below. As youll see below, the combination of formulary exclusion and private labels is creating an increasingly confusing and crowded biosimilar marketplace.
Researchers used the environmental circumstances and fecal samples collected from the six years prior to the severe El Ni o drought in Costa Rica to study the relationship between the endocrinologic stress response and survival in white-faced capuchin monkeys. Monkeys who showed a steeper rise in these stress hormones during the mild droughts were more likely to survive the severe El Nino drought.
The Unseen Heroes of Generic Drug Manufacturing: Good Manufacturing Practice (GMP) As we navigate the complex world of generic drug manufacturing, it's easy to overlook the unsung heroes that ensure the quality and safety of these life-saving medications. I'm talking about Good Manufacturing Practice (GMP), a set of guidelines that govern the production, testing, and packaging of generic drugs.
Thanks to a new technology called Moscot ('Multi-Omics Single-Cell Optimal Transport'), researchers can now observe millions of cells simultaneously as they develop into a new organ -- for example, a pancreas.
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