Broad Institute

FEBRUARY 19, 2024

Largest and most diverse genome-wide association study of type 2 diabetes reveals new genetic factors By Claire Hendershot February 19, 2024 Breadcrumb Home Largest and most diverse genome-wide association study of type 2 diabetes reveals new genetic factors By studying a diversity of participants, scientists find nearly 150 new locations in the genome linked to type 2 diabetes risk.

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Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- When settling into your senior years, you need to be especially careful when taking medicines, herbal remedies and supplements, the U.S. Food and Drug Administration says.That’s because older adults are likely to use.

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FDA Drugs 119

Broad Institute

FEBRUARY 19, 2024

Genetic risk prediction for 10 chronic diseases moves closer to the clinic By Corie Lok February 19, 2024 Breadcrumb Home Genetic risk prediction for 10 chronic diseases moves closer to the clinic As part of a nationwide collaboration, Broad Clinical Labs researchers have optimized 10 polygenic scores for use in clinical research as part of a study on how to implement genetic risk prediction for patients.

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Science Daily: Pharmacology News

FEBRUARY 19, 2024

Researchers have developed a powerful new artificial intelligence model that can distinguish between male and female brains.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2021 -- Bad breath: No one wants it, but its origins have long remained unclear. Now, Japanese researchers have gotten a bit closer to understanding how bad breath begins, and perhaps ways to treat it.The roots of the malady.

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Science Research 110

Science Daily: Pharmacology News

FEBRUARY 19, 2024

A new study shows there is a gender gap between women and men when it comes to exercise. The findings show that women can exercise less often than men, yet receive greater cardiovascular gains.

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Science Daily: Pharmacology News

FEBRUARY 19, 2024

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies.

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Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- There's good news for females who think that men shed pounds faster than women do: New research shows women get more health benefits from exercise than men, even if they put in less effort.

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Research 103

Perficient: Drug Development

FEBRUARY 19, 2024

You may learn microservices in-depth from beginner to expert in this set of tutorials. click here for previous blog: – Tutorial 01 – Microservices Architectural Design by using Spring Boot Introduction: – Netflix Eureka Server – To enable discovery and communication between microservices, it is necessary to register or publish the microservice with the R&D (Registrar and Discovery) server.

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Packaging International 101

Chemical Biology and Drug Design

FEBRUARY 19, 2024

Icariin promoted BMSC osteogenic differentiation via enhancing cell viability, ALP activity, mineralization levels, OCN, and OPN levels by mediating the USP47/SIRT1/Wnt/β-catenin pathway. Abstract Icariin has been shown to promote osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). However, the underlying molecular mechanism by which Icariin regulates osteogenic differentiation needs to be further revealed.

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Regulations Protein Expression Research 100

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Patent Watch

FEBRUARY 19, 2024

Annual Drug Patent Expirations for LATUDA Latuda is a drug marketed by Sunovion Pharms Inc and is included in one NDA. It is available from one supplier. There are nine… The post New patent expiration for Sunovion Pharms drug LATUDA appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- A shift in parenting early in a child's development might help curb the symptoms of attention-deficit hyperactivity disorder (ADHD), new research suggests. When a preschooler exhibits an "excitable or exuberant".

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Research 94

PPD

FEBRUARY 19, 2024

The European Union Clinical Trial Regulation (EU CTR) brings the biggest change in the regulatory landscape since the implementation of the EU Clinical Trials Directive in 2004, requiring vast changes in the way organizations are structured and conduct their day-to-day activities. The updated regulation is now the mandatory regulatory framework for which new applications for interventional and low interventional clinical trials in the EU must be assessed and authorized.

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Clinical Trials Regulations Trials Clinical Research 92

SCIENMAG: Medicine & Health

FEBRUARY 19, 2024

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

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International Research 79

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Clinical Trials

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- The U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer. Amtagvi, made by Iovance Biotherapeutics Inc., becomes the first cellular therapy approved to.

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FDA Approval Treatment FDA Therapies 72

SCIENMAG: Medicine & Health

FEBRUARY 19, 2024

PITTSBURGH, Feb. 19, 2024 – University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk. The findings were published in Nature Metabolism today. Credit: University of Pittsburgh PITTSBURGH, Feb.

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Research 75

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- Increased access to prescription opioids has driven up U.S. suicide rates by making it easier to women to end their lives, a new study claims.The study also blames a shrinking federal safety net during tough economic times.

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SCIENMAG: Medicine & Health

FEBRUARY 19, 2024

February 19, 2024, Cleveland: Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

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Disease Clinical Research Research 71

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Clinical Trials

Science Daily: Pharmacology News

FEBRUARY 19, 2024

Hydrogels are already used in clinical practice for the delivery of drugs, and as lenses, bone cement, wound dressings, 3D scaffolds in tissue engineering and other applications. However, bonding different hydrogel polymers to one another has remained a challenge; yet it could enable numerous new applications. Now, researchers have pioneered a new method that uses a thin film of chitosan, a fibrous sugar-based material derived from the processed outer skeletons of shellfish, to make different hy

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Drug Patent Watch

FEBRUARY 19, 2024

This chart shows the pharmaceutical companies with the most insert dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most insert dosed drugs… The post Which pharmaceutical companies have the most insert dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmaceutical Companies Pharmaceuticals Drugs 59

FDA Law Blog: Biosimilars

FEBRUARY 19, 2024

Hyman, Phelps & McNamara, P.C. (“HP&M”) is pleased to announce that Ana Loloei has joined the firm as Counsel. Ms. Loloei is a 14-year veteran of the FDA, where most recently she served as a Senior Regulatory Counsel in the Office of Policy at CDRH. While at FDA, Ms. Loloei also served as a Senior Policy Advisor in CDRH and as a Special Advisor in the Office of the Commissioner.

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FDA Engineering Regulations Production 59

Drug Patent Watch

FEBRUARY 19, 2024

Annual Drug Patent Expirations for KYNMOBI Kynmobi is a drug marketed by Sumitomo Pharma Am and is included in one NDA. There are fifteen patents protecting this drug. Drug patent… The post New patent expiration for Sumitomo Pharma drug KYNMOBI appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- Raw milk cheese tainted with E. coli bacteria has sickened 10 people in four states, hospitalizing four, federal regulators warn. The cases have been tied to Raw Farm brand raw cheddar cheese, the U.S. Centers for Disease.

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Hospitals Regulations Disease 59

Drug Patent Watch

FEBRUARY 19, 2024

Annual Drug Patent Expirations for SYMPAZAN Sympazan is a drug marketed by Otter Pharms and is included in one NDA. It is available from one supplier. There are three patents… The post New patent expiration for Otter Pharms drug SYMPAZAN appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- Hispanic Americans who are hospitalized and placed on ventilators have a higher risk of death than their white peers, and new research may reveal a reason why. The study found that Hispanic patients in respiratory failure.

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Hospitals Research 59

Drug Patent Watch

FEBRUARY 19, 2024

Annual Drug Patent Expirations for EXSERVAN Exservan is a drug marketed by Aquestive and is included in one NDA. It is available from one supplier. There are two patents protecting… The post New patent expiration for Aquestive drug EXSERVAN appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- Millions of Black and Hispanic middle-class adults won’t be able to afford senior housing and health care expenses as they grow old, a new study warns.The number of middle-income older adults of color is expected to.

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thought leadership

FEBRUARY 19, 2024

This article has been updated since its original publication date. Navigating the complexities of Corrective Action / Preventive Action (CAPA) in the drug and medical device industries often poses a significant challenge, a sentiment echoed through real-life observation from ProPharma Quality and Compliance Consultants. Drawing from our wealth of experience in handling numerous CAPA-related projects, this article offers firsthand insights and effective strategies to successfully manage CAPA with

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Compliance Drugs FDA Science 59

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- One in 10 homeless people has a pet, and one-stop health clinics where both can get health care would benefit both, a new study suggests.The study, published Feb. 19 in the journal Human-Animal Interactions, found that.

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Vial

FEBRUARY 19, 2024

Join Dr. Ahmed Hamdy, CEO of Vincerx Pharma, on a compelling journey through oncology. From co-founding Acerta Pharma to pioneering patient-centric innovations, Dr. Hamdy shares his impactful career. Explore the groundbreaking VersAptx bioconjugation platform, designed to elevate cancer therapies and uncover the delicate balance between clinical excellence and commercial viability in the dynamic landscape of pharmaceuticals.

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Small Molecule Therapies Treatment Science 52

Drugs.com

FEBRUARY 19, 2024

MONDAY, Feb. 19, 2024 -- The U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes the first cellular therapy approved to.

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FDA Approval Treatment FDA Therapies 59

Alta Sciences

FEBRUARY 19, 2024

Altasciences Has You Covered From Coast to Coast blussier Mon, 02/19/2024 - 22:01 HTML Altasciences Has You Covered From Coast to Coast Accelerate your drug development timelines by up to 40% with an integrated CRO/CDMO by your side, from lead candidate selection to clinical proof of concept, and beyond. Our scientific and operational teams move in unison to provide a seamless and synchronized drug development roadmap with research activities running in parallel.

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Clinical Trials Drug Development Trials Research 52

Perficient: Drug Development

FEBRUARY 19, 2024

The rise of omnichannel operations has redefined the landscape, placing new demands on the roles of VP of Supply Chain, VP of Store Operations, and Directors of Omnichannel Operations. The introduction and expansion of same-day delivery services have particularly spotlighted the intricate balance between customer expectations and operational feasibilities.

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