Sun.Dec 10, 2023

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‘No tolerance for failure’: An oral history of the first CRISPR medicine

BioPharma Drive: Drug Pricing

A new sickle cell disease therapy developed by CRISPR Therapeutics and Vertex Pharmaceuticals is now approved in the U.S. and U.K. This is the story of how it came to be.

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Decoding Pfizer’s Portfolio: A New Model for Precision in Pharma Investments

Drug Patent Watch

In the ever-evolving landscape of the biotech and pharmaceutical sectors, accurate valuation of post-revenue drug assets stands as the linchpin for informed and strategic decision-making. The significance of this valuation… The post Decoding Pfizer’s Portfolio: A New Model for Precision in Pharma Investments appeared first on DrugPatentWatch - Make Better Decisions.

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'Exceptional' results in phase III leukemia trial

Science Daily: Pharmacology News

Leukaemia trial shows 'exceptional' results. Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase III trial has found. Adult patients were given a combination of cancer growth blocking drugs over varied durations depending on how rapidly their disease responded. More than 19 in 20 patients were in remission three years after starting treatment -- a significant improvement in progression-free and overall survival comp

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Pfizer marks progress for successor sickle cell drug at ASH

BioPharma Drive: Drug Pricing

While new gene therapies for the blood disease grabbed headlines at ASH, Pfizer presented fresh data for an oral drug meant to build on its marketed therapy Oxbryta.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Pharmaceutical companies with the most ‘New Chemical Entity’ drugs

Drug Patent Watch

Five years of exclusivity is provided for drugs which do not contain active molecules that have appeared in previously-approved drugs. This is one of the longest exclusivity terms provided by… The post Pharmaceutical companies with the most ‘New Chemical Entity’ drugs appeared first on DrugPatentWatch - Make Better Decisions.

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What Biology Can Learn from Physics

Codon

I. Moonshots Physics was long dominated by solitary celebrities. Newton formulated laws of motion, Einstein developed a theory of relativity, and Dirac sculpted a general theory of quantum mechanics. But then, World War II changed the equation. The Manhattan project employed 130,000 people and cost $2.2 billion , or more than $25 billion in today’s dollars.