Science Daily: Pharmacology News

APRIL 17, 2024

Even if CO2 emissions were to be drastically cut down starting today, the world economy is already committed to an income reduction of 19% until 2050 due to climate change, a new study finds. These damages are six times larger than the mitigation costs needed to limit global warming to two degrees. Based on empirical data from more than 1,600 regions worldwide over the past 40 years, scientists assessed future impacts of changing climatic conditions on economic growth and their persistence.

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Drug Target Review

APRIL 17, 2024

What were the key findings regarding the influence of HLA molecules on lung cancer risk? Dr Chowell : Heterozygosity at HLA-II, but not HLA-I, was found to be enriched in controls relative to cases with lung cancer and was associated with a reduced risk of developing lung cancer over time, as well as a reduced lifetime risk of lung cancer among former and current smokers but not among never-smokers.

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Science Daily: Pharmacology News

APRIL 17, 2024

Investigators have discovered how brain cells responsible for working memory--the type required to remember a phone number long enough to dial it--coordinate intentional focus and short-term storage of information.

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Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Zepbound, one of the wildly popular weight-loss drugs that millions of Americans now take, eased sleep apnea in obese adults in two company trials, drug maker Eli Lilly announced Wednesday.First approved to treat.

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Trials Drugs 111

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Science Daily: Pharmacology News

APRIL 17, 2024

Soft skin coverings and touch sensors have emerged as a promising feature for robots that are both safer and more intuitive for human interaction, but they are expensive and difficult to make. A recent study demonstrates that soft skin pads doubling as sensors made from thermoplastic urethane can be efficiently manufactured using 3D printers.

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Perficient: Drug Development

APRIL 17, 2024

Empowering Automation in the Digital Era In this highly digitally connected world, companies are always looking for new and creative ways to improve efficiency, simplify procedures, and provide better customer service. Robotic Process Automation (RPA) has become a game-changing technology that helps businesses accelerate up operations, cut down on human error, and automate repetitive activities.

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Compliance Production Marketing 105

BioPharma Drive: Drug Pricing

APRIL 17, 2024

The companies plan to launch their copycat version of the blockbuster immune disease drug early next year, per a legal settlement with J&J.

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Biosimilars FDA Disease Drugs 120

Science Daily: Pharmacology News

APRIL 17, 2024

The fossilized remains of a second gigantic jawbone measuring more than two meters long has been found on a beach in Somerset, UK.

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Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Active women using the pill appear to receive an added bonus from their birth control, a new study says.These women are less likely to suffer sprains and strains than women not on birth control, researchers reported.

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Research 111

Science Daily: Pharmacology News

APRIL 17, 2024

The warming climate shifts the dynamics of tundra environments and makes them release trapped carbon, according to a new study published in Nature. These changes could transform tundras from carbon sinks into a carbon source, exacerbating the effects of climate change.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Microplastics could be migrating from the digestive tract into the kidneys, livers and brains of human beings, a new mouse study suggests.Lab mice exposed to microplastics in their drinking water wound up with the tiny.

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Science Daily: Pharmacology News

APRIL 17, 2024

Mountain chickadees have among the best spatial memory in the animal kingdom. New research identifies the genes at play and offers insight into how a shifting climate may impact the evolution of this unique skill.

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Research 114

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Two-thirds of homeless people are experiencing some form of mental health disorder, a large, new review of data on the subject.The analysis found that men who are homeless are more likely to be battling mental illness.

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Science Daily: Pharmacology News

APRIL 17, 2024

Astronomers have discovered methane emission on a brown dwarf, an unexpected finding for such a cold and isolated world. The findings suggest that this brown dwarf might generate aurorae similar to those seen on our own planet as well as on Jupiter and Saturn.

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Clinical Trials

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Changes in gut bacteria have been linked to a variety of different diseases, including type 2 diabetes, obesity and inflammatory bowel disease.Now, a new study indicates that gut bacteria also might play a role in a.

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Disease 98

Science Daily: Pharmacology News

APRIL 17, 2024

It's not a single pesticide or virus stressing honey bees, and affecting their health, but exposure to a complex web of multiple interacting stressors encountered while at work pollinating crops, found new research. Scientists have been unable to explain increasing colony mortality, even after decades of research examining the role of specific pesticides, parasitic mites, viruses or genetics.

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Virus Research 113

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Eating healthy can lower the risk of heart disease in breast cancer survivors, a new study has found.Heart disease is a top cause of death in women who've survived breast cancer, likely due to the toxic effects of.

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Disease 98

Science Daily: Pharmacology News

APRIL 17, 2024

Pioneering study reveals that limiting global warming to 1.5 degrees Celsius could reduce the global economic costs of climate change by two thirds. If warming continues to 3 degrees Celsius, global GDP will decrease by up to 10 percent -- with the worst impacts in less developed countries.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- In a new study, people living with HIV who got standard meds to keep the virus at bay also had much lower rates of Alzheimer's disease -- suggesting the drugs might also lower risks for the brain illness.It's.

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Virus Disease Drugs 98

Science Daily: Pharmacology News

APRIL 17, 2024

New research has highlighted an area in Arabia that once acted as a key point for cultural exchanges and trades amongst ancient people -- and it all took place in vast caves and lava tubes that have remained largely untapped reservoirs of archaeological abundance in Arabia. Through meticulous excavation and analysis, the international team uncovered a wealth of evidence at Umm Jirsan, spanning from the Neolithic to the Chalcolithic/Bronze Age periods (~10,000-3,500 years ago).

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International Research 103

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Some people with tough-to-treat epilepsy might benefit if doctors target a brain region newly linked to the disorder, a new study suggests.Seizures declined by 83% after a patient underwent surgery that removed almost.

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Doctors 98

Science Daily: Pharmacology News

APRIL 17, 2024

Marine communities migrated to Antarctica during the Earth's warmest period in 66 million years long before a mass-extinction event.

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Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- The placenta could be one reason why some women develop gestational diabetes during pregnancy, a new study finds.A deficit in the way the placenta expresses the gene for a hormone called insulin-like growth factor 1.

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NIOSH Science Blog: Drugs

APRIL 17, 2024

Historically, junior firefighter programs have been an important recruitment and retention tool for the fire service. Also known as “explorers” or “cadets,” junior firefighters range from 14-17 years of age and are part of volunteer, career, and combination (career/volunteer) fire departments. Most states’ child labor laws limit their participation to only fundraising activities, training, or support work at fireground or rescue operations such as rolling up hoselines or providing first aid as d

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Science Daily: Pharmacology News

APRIL 17, 2024

Scientists have developed a new method using knot theory to find the optimal routes for future space missions without the need to waste fuel.

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Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- There’s no evidence that a COVID infection increases the risk of asthma in children, the first study to date on the subject finds.“We knew from a number of really nice studies over the last decade or more that.

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Science Daily: Pharmacology News

APRIL 17, 2024

Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago. Researchers have shown that an Amazonian butterfly is a hybrid species, formed by two other species breeding together almost 200,000 years ago.

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Research 86

Drugs.com

APRIL 17, 2024

WEDNESDAY, April 17, 2024 -- Two implanted heart devices used by patients in end-stage heart failure are now under a strict U.S. Food and Drug Administration recall, after being tied to 273 known injuries and 14 deaths, the agency said Tuesday.The.

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FDA Drugs 97

Science Daily: Pharmacology News

APRIL 17, 2024

The Warm Arctic-Cold Continent (WACC) phenomenon is the puzzling combination of Arctic warming and extreme coldness in specific mid-latitude regions. However, the progression of WACC events remains unclear amidst global warming. Scientists have now predicted a sharp decline in the WACC phenomenon post-2030s, affecting extreme weather events. These findings offer critical insights for communities, scientists, and policymakers to refine climate models and strategies and battle climate change.

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BioPharma Drive: Drug Pricing

APRIL 17, 2024

Following negative results, the company doesn’t plan to further test SAGE-718 in Parkinson’s. Other studies in Huntington’s and Alzheimer’s remain ongoing.

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Drugs 75

Antidote

APRIL 17, 2024

Participating in medical research is something individuals do for various reasons. Whether a person is interested in contributing to science, accessing potential new treatments, or receiving condition-specific care from experts, there are many benefits to being a clinical trial volunteer — but how does one start the enrollment process?

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BioPharma Drive: Drug Pricing

APRIL 17, 2024

Positive data for Lilly’s medicine tirzepatide in sleep apnea are the latest signal the benefits of GLP-1 agonists could extend beyond diabetes and weight loss.

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Drugs 72

Cytel

APRIL 17, 2024

Written by Grace Hsu, Evie Merinopoulou, and Jason Simeone To establish treatment efficacy and safety, regulatory and reimbursement decision-makers have traditionally preferred evidence from randomized clinical trials, which, by design, have a low risk of bias. However, single-arm trials (SAT) using an external control arm (ECA) are commonly performed for ethical reasons, due to the difficulties in identifying a suitable comparator arm(s) for head-to-head trials in a rapidly evolving therapeutic

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Clinical Trials Trials Disease Treatment 59