Science Daily: Pharmacology News
MARCH 5, 2024
Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.
Chemical Biology and Drug Design
MARCH 5, 2024
Curcumin modulates the gene and protein expression levels of ferroptosis mediators via JNK signaling. Abstract Recent evidence has proved that curcumin as a natural polyphenol have a great anticancer and anti-proliferative effects in cancer cells. Ferroptosis, a new form of regulated cell death, plays a vital role in the pathogenesis and therapy of cancers.
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BioPharma Drive: Drug Pricing
MARCH 5, 2024
The study results further validate Roche’s recent decision to acquire rights to the drug, which is being developed for people with a stubborn form of hypertension.
Chemical Biology and Drug Design
MARCH 5, 2024
Caffeic acid grafted chitooligosaccharides (CA-COS) showed anti-inflammatory effect against LPS- Stimulated RAW264.7 Cells. CA-COS was downregulated the cytokines including TNF-α, IL-1β, IL-6 in RAW264.7 cells. CA-COS was downregulated NF-kB and MAPKs signaling pathways in RAW264.7 cells. CA-COS exhibited low toxicity and significantly enhance the anti-inflammatory activities of COS.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MARCH 5, 2024
Fossils of a strange new species of marine lizard with dagger-like teeth that lived 66 million years ago, show a dramatically more biodiverse ocean ecosystem to what we see today.
Chemical Biology and Drug Design
MARCH 5, 2024
Biotin-SS-IR820 displays significantly enhanced cellular uptake amount, enhanced in vitro photocytotoxicity and enhanced in vivo tumor accumulation as compared to IR820, showing great potential for targeted theranostics of biotin receptor overexpressed tumors. Abstract New indocyanine green (ICG) (IR820) is one of the ICG derivatives and attracts increasing attention for cancer management.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Chemical Biology and Drug Design
MARCH 5, 2024
Herein, we describe the synthesis of quinoxaline-isoxazole-piperazine conjugates (5a–n) and their in vitro anticancer efficiency against three different human cancer cell lines: MCF-7, HepG-2, and HCT-116. The anticancer activity results reveal that the three compounds ( 5d , 5f, and 5e) showed potential effectiveness against all the tested cell lines compared to standard etoposide.
Perficient: Drug Development
MARCH 5, 2024
Adobe Launch is a valuable tool to help you manage the tags placed across your website, including Facebook, Pinterest, and Bing pixels as well as Adobe Analytics and Target depending on your property. Many of these tags are either deployed via custom code or via one of the many extensions within Launch’s extension to help you manage your tags. However, as your implementation grows over time, you may find that it becomes difficult to handle due to several factors, including any dependencies on ex
Drug Target Review
MARCH 5, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My STEM journey began early in my childhood, thanks to my father, a mathematician and economist whose job took him around the globe. He would return from his travels with an assortment of magazines, often including a scientific journal in the mix.
Perficient: Drug Development
MARCH 5, 2024
This article is just to know the configuration of tRestRequest, tRestResponse and How can we create the HTTP listeners using postman. Create a job in talend tool (It can be talend ESB, talend Data fabric). Once created a job place tRestRequest , tjavaRow component and tRestResponse in designer. Talend Designer – job created and component placed.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
MARCH 5, 2024
A team of astronomers has shed new light on the fascinating and complex process of planet formation. The research brings together observations of more than 80 young stars that might have planets forming around them, providing astronomers with a wealth of data and unique insights into how planets arise in different regions of our galaxy.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Certain drugs used to treat multiple sclerosis appear to be safe for babies if taken by breastfeeding moms, a new study finds.Breastfed babies whose moms received monoclonal antibody treatments for MS did not develop any.
Quanticate
MARCH 5, 2024
What is an ISS and an ISE? The integrated summary of safety (ISS) and integrated summary of effectiveness (ISE) are critical documents required for regulatory submissions in the approval of new medicines/drugs or devices. These documents combine the safety and efficacy results from different clinical trials conducted for the investigational product and need to contain detailed analyses of all relevant data from the individual clinical study reports.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Many people protected by drugs that prevent HIV infection quit using them, upping their vulnerability to the virus that causes AIDS, new research shows.The drug combo known as pre-exposure prophylaxis (PrEP) is now a.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
MARCH 5, 2024
A new fossil, named 'Attenborough's strange bird' after naturalist and documentarian Sir David Attenborough, is the first of its kind to evolve a toothless beak. It's from a branch of the bird family tree that went extinct in the mass extinction 66 million years ago, and this strange bird is another puzzle piece that helps explain why some birds -- and their fellow dinosaurs -- went extinct, and others survived to today.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Statins have become the miracle medicine of modern heart care, lowering cholesterol levels and and guarding against heart attacks in millions of Americans.In fact, a running joke among doctors holds that statins are so.
Science Daily: Pharmacology News
MARCH 5, 2024
Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Analysis of a "chemical score" from mouth lesion swab samples might allow patients to skip painful biopsies, getting oral cancers promptly diagnosed in a noninvasive way, scientists report.Right now, dentists and other.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
SCIENMAG: Medicine & Health
MARCH 5, 2024
EL PASO, Texas (March 5, 2024) – Health researchers at The University of Texas at El Paso are launching a clinical trial to improve walking in the El Paso community, thanks to a $4.4 million grant from the National Institutes of Health (NIH).
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Almost 2 million Americans incarcerated in the nation's jails and prisons suffer through an average 100 days per year of dangerous heat and humidity, a new report finds.A warming world will only increase that danger, say.
SCIENMAG: Medicine & Health
MARCH 5, 2024
A new review paper from authors at Brigham and Women’s Hospital and collaborators concludes that menopause does not uniformly elevate the risk of depression and other mental health conditions.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- A new robotic hip exoskeleton could help stroke patients improve their walking stride, a new study shows.More than 80% of stroke survivors develop problems walking, often because their step is shorter on one side than the.
Drug Channels
MARCH 5, 2024
Dr. Adam J. Fein, president of Drug Channels Institute (DCI) and the author of Drug Channels , invites you to join him for DCI’s latest live video webinar: Drug Channel Implications of the Inflation Reduction Act This event will be broadcast live on Friday, April 5, 2024, from 12:00 p.m. to 1:30 p.m. ET This post describes the event and explains how to purchase a registration.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- A new smartphone app can help doctors more accurately diagnose ear infections in babies and small children, potentially reducing unnecessary antibiotic use in kids, researchers report.Ear infections -- known by doctors as.
Science Daily: Pharmacology News
MARCH 5, 2024
In good news for office workers, a new study from the University of Sydney, Australia has found increasing your step count may counteract the health consequences of too much sedentary time each day.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- A cheap cavity-fighting liquid typically used to treat sensitive teeth appears to work as well as dental sealants in preventing tooth decay, a new study finds.A single treatment of either silver diamine fluoride (SDF) or a.
Science Daily: Pharmacology News
MARCH 5, 2024
It takes more than a galaxy merger to make a black hole grow and new stars form: machine learning shows cold gas is needed too to initiate rapid growth -- new research finds.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Sipping sodas – sugary or diet – seems to slightly increase a person’s risk of developing a potentially dangerous irregular heart rhythm, a new study shows.Folks had a 20% greater risk of atrial fibrillation if they.
Science Daily: Pharmacology News
MARCH 5, 2024
Out-of-control behavior by CEOs and other powerful people constantly makes headlines -- so much so that some might consider impulsivity a pathway to power. New research finds that having self-control is often what leads to power.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Long COVID might be triggered by low iron levels in the blood from the person’s initial infection, a new study claims.It’s remained a mystery why an estimated three out of 10 people infected with COVID go on to suffer.
Science Daily: Pharmacology News
MARCH 5, 2024
NASA's Juno spacecraft has directly measured charged oxygen and hydrogen molecules from the atmosphere of one of Jupiter's largest moons, Europa. These observations provide key constraints on the potential oxygenation of its subsurface ocean.
Drugs.com
MARCH 5, 2024
TUESDAY, March 5, 2024 -- Are you typically getting only a few hours sleep each night? Besides leaving you groggy all day, your insomnia could also be raising your odds for type 2 diabetes, new research shows.Compared to people who slept the.
SCIENMAG: Medicine & Health
MARCH 5, 2024
Next time you’re packing lunch for your kid or reaching for a healthy afternoon bite, consider this: only three types of fruit snacks – dried fruit, fruit puree and canned fruit with juice – meet the latest recommendations for high-nutrition snacks set by federal dietary guidelines, according to research by University of Massachusetts Amherst food […]
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