Tue.Jan 14, 2025

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Gene editing extends lifespan in mouse model of prion disease

Broad Institute

Gene editing extends lifespan in mouse model of prion disease By Allessandra DiCorato January 14, 2025 Breadcrumb Home Gene editing extends lifespan in mouse model of prion disease A single-letter edit in DNA reduces levels of the disease-causing prion protein in the brain and could lead to a preventative, one-time treatment for the deadly neurodegenerative disorder.

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This metaphorical cat is both dead and alive -- and it will help quantum engineers detect computing errors

Science Daily: Pharmacology News

Engineers have demonstrated a well-known quantum thought experiment in the real world. Their findings deliver a new and more robust way to perform quantum computations and they have important implications for error correction, one of the biggest obstacles standing between them and a working quantum computer.

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5 questions facing emerging biotech in 2025

BioPharma Drive: Drug Pricing

Young drugmakers confront several harsh realities this year, among them a contracting sector and competition from China.

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Floating solar panels could support US energy goals

Science Daily: Pharmacology News

Federal reservoirs could help meet the country's solar energy needs, according to a new study. Geospatial scientists and senior legal and regulatory analyst quantified exactly how much energy could be generated from floating solar panel projects installed on federally owned or regulated reservoirs.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Lilly blames slower-than-expected growth for 2024 sales miss

BioPharma Drive: Drug Pricing

The company said it overestimated demand of its obesity and diabetes drugs in the fourth quarter, but projected a further ramp-up in sales this year.

Drugs 294

More Trending

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JPM25: Amgen’s defense, Merck’s patent ‘hill’ and Viking’s long-term planning

BioPharma Drive: Drug Pricing

Executives at Amgen made the case for MariTide's differentiation, while Merck's CEO contended that Keytruda's coming loss of exclusivity can be managed.

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Updated Guidelines for Preventing Osteoporosis-Related Fractures Released

Drugs.com

TUESDAY, Jan. 14, 2025 -- All women 65 and older should continue to be screened for osteoporosis, the nation’s leading preventive health panel says in an updated recommendation. The U.S. Preventive Services Task Force also recommends.

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Scientific workflow for hypothesis testing in drug discovery: Part 2 of 3

Drug Target Review

Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Operating a workflow, such as the one described in Figure 1, involves several key considerations that affect both the accuracy of results and the efficiency of the research process. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery.

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Diabetes Drug Protects Against Skin Cancer, New Research Says

Drugs.com

TUESDAY, Jan. 14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says.Metformin significantly reduces peoples risk of developing basal cell cancers or squamous cell cancers, the two most common skin c.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Regenxbio licenses gene therapies to Japan’s Nippon Shinyaku

BioPharma Drive: Drug Pricing

Nippon Shinyaku will pay Regenxbio $110 million upfront for U.S. and Asia rights to treatments for Hunter and Hurler syndromes.

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Diabetes Drug, Metformin, Protects Against Skin Cancer, New Research Says

Drugs.com

TUESDAY, Jan. 14, 2025 -- A popular diabetes drug can provide protection against skin cancers, a new study says. Metformin significantly reduces people’s risk of developing basal cell cancers or squamous cell cancers, the two most common skin.

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FTC again goes after PBMs’ business practices in new report

BioPharma Drive: Drug Pricing

Agency commissioners voted unanimously on Tuesday to publish the report, which makes a similar attack on the drug middlemen as the agency’s first report, but draws on more data.

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Men Are 3 Times As Likely to Die from Traumatic Brain Injury Compared to Women

Drugs.com

TUESDAY, Jan. 14, 2025 -- Men are more than three times as likely to die from a traumatic brain injury compared to women, a new study says. About 30 brain injury-related deaths occurred for every 100,000 U.S. men in 2021, while only 9 such deaths.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Mastering Database.SaveResult in Batch Class: A Beginner-Friendly Guide

Perficient: Drug Development

Imagine youre a skilled craftsman working in a massive warehouse. Every day, your task is to process thousands of unique items and ensure that each one is properly logged and stored. But lets face it mistakes happen. Sometimes an item gets mislabeled or damaged, and you need to know which ones to fix, and which ones made it safely through. In Salesforce, when working with a batch class that processes thousands or even millions of records, Database.SaveResult acts as your trusty supervisor, keep

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U.S. Dementia Cases Expected to Double By 2060

Drugs.com

TUESDAY, Jan. 14, 2025 -- Seniors risk of dementia is more than double what was previously thought.The risk of developing dementia after age 55 is more than 42% among Americans, researchers reported in a study published Jan. 13 in the journal N.

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Drug Patent Expirations for the Week of January 12, 2025

Drug Patent Watch

UZEDY (risperidone) Teva Patent: 10,736,965 Expiration: Jan 12, 2025 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.

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Sleep Deprivation Lets Intrusive Memories, Bad Thoughts Into the Mind

Drugs.com

TUESDAY, Jan. 14, 2025 -- People with post-traumatic stress disorder (PTSD) are plagued by unwanted and distressing memories over which they have little to no control.Doctors now think they understand why PTSD patients and others arent able to k.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Cell and Gene Therapies for CNS and Ocular Delivery

Alta Sciences

Cell and Gene Therapies for CNS and Ocular Delivery tchichekian Tue, 01/14/2025 - 15:04 Image Website_Webinar_GACT.

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The New Definition of Obesity

Drugs.com

The way obesity is diagnosed needs to become more sophisticated, an international commission has concluded.Using body-mass index (BMI) to tell who is overweight or obese is not reliable, and can result in misdiagnosis, the Commission on Clinical.

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Webinar-A Square Peg in a Round Hole

Alta Sciences

Webinar-A Square Peg in a Round Hole tchichekian Tue, 01/14/2025 - 15:09 Image Website_Webinar_PSYCH.

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It May Be Easier to Quit Smoking With Holistic or Integrated Health Approach

Drugs.com

TUESDAY, Jan. 14, 2025 -- It takes a village to help a smoker quit. And a new study published recently in JAMA Internal Medicine shows that smokers had a nearly doubled success rate quitting when supported by an integrated approach that included.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Webinar-A Square Peg in a Round Hole

Alta Sciences

Webinar-A Square Peg in a Round Hole tchichekian Tue, 01/14/2025 - 15:09 Image Social-Media_Webinar_PSYCH_OnDemand_V2.

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Are Young People With Eating Disorders Predisposed to Them?

Drugs.com

TUESDAY, Jan. 14, 2025 -- Eating disorders appear to be linked to differences in brain structure among teenagers.Young adults who develop eating disorders appear to have delayed brain maturation as teenagers, MRI scans show in a new study published.

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The Altascientist - Psychedelics and Entactogens

Alta Sciences

The Altascientist - Psychedelics and Entactogens tchichekian Tue, 01/14/2025 - 15:17 Image Social media_Audio book_The Altascientist_issue 19_CNS Hallucinogens.

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More Abortions Tied to Natural Family Planning or Fertility Awareness Methods

Drugs.com

TUESDAY, Jan. 14, 2025 -- Relying on natural and fertility awareness methods to prevent pregnancy might be linked to an increase in abortions, a new study suggests. Use of hormonal birth control methods like the pill has declined by nearly half.

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The Altascientist - The Effects of Drugs on Driving

Alta Sciences

The Altascientist - The Effects of Drugs on Driving tchichekian Tue, 01/14/2025 - 15:20 Image Resource-Center_e-bulletin_The_Altascientist_issue_1.

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