Wed.Sep 25, 2024

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World's oldest cheese reveals origins of kefir

Science Daily: Pharmacology News

Scientists successfully extracted and analyzed DNA from ancient cheese samples found alongside the Tarim Basin mummies in China, dating back approximately 3,600 years. The research suggests a new origin for kefir cheese and sheds light on the evolution of probiotic bacteria.

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Commercial interests contribute to drug use and addiction

National Institute on Drug Abuse: Nora's Blog

Commercial interests contribute to drug use and addiction mfleming Wed, 09/25/2024 - 15:00 Nora's Blog September 26, 2024 Image ©Getty Images/ PeopleImages Biomedical sciences are bringing increased focus to social determinants of health, which the World Health Organization (WHO) defines as “the conditions in which people are born, grow, work, live, and age, the systems put in place to deal with illness, and the wider set of forces and systems shaping the conditions of daily life.” 1 Very often,

Drugs 111
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Major boost in carbon capture and storage essential to reach 2°C climate target

Science Daily: Pharmacology News

Large expansion of carbon capture and storage is necessary to fulfill the Paris Climate Agreement. Yet a new study shows that without major efforts, the technology will not expand fast enough to meet the 2 C target and even with major efforts it is unlikely to expand fast enough for the 1.5 C target.

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BRAIN at 10: A View from the National Institute on Drug Abuse

National Institute on Drug Abuse: Nora's Blog

BRAIN at 10: A View from the National Institute on Drug Abuse mfleming Wed, 09/25/2024 - 19:31 Nora's Blog October 1, 2024 By Nora Volkow, MD, Director, and Rita Valentino, Ph.D., Director, Division of Neuroscience and Behavior, NIDA This blog was originally posted on the The BRAIN Blog. The BRAIN Initiative is marking a milestone—10 years of& advancing neuroscience and neurotechnology research by funding innovative projects.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Single-dose gene therapy is potentially life-changing for adults with hemophilia B

Science Daily: Pharmacology News

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an international Phase III clinical trial.

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Could Ozempic Help Prevent Opioid Overdoses?

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- In a finding that suggests Ozempic and Wegovy have powers that extend beyond weight loss, a new study finds the medications might also lower people’s risk of opioid overdose. People with type 2 diabetes prescribed.

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Free COVID Tests Back Again by End of September

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- As Americans get ready for fall and winter, the U.S. government is offering another round of free COVID tests, available by the end of this month."U.S. households will be eligible to order 4 free COVID-19 tests at.

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Deep-sea discovery shines light on life in the twilight zone

Science Daily: Pharmacology News

A new study could change the way scientists view microbial processes in the deep ocean. The unexpected findings expand our understanding of the impacts of climate change, including how and where the ocean stores carbon.

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Looking beyond traditional oncogenic pathways to break cancer resistance

Drug Target Review

Targeted cancer therapies and treatment resistance mechanisms Targeted cancer therapies such as epidermal growth factor receptor (EGFR), Kirsten rat sarcoma virus (KRAS), or V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) inhibitors have made a significant positive impact in the treatment of solid tumours, specifically for patients exhibiting oncogenic mutations.

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Webb discovers 'weird' galaxy with gas outshining its stars

Science Daily: Pharmacology News

The discovery of a 'weird' and unprecedented galaxy in the early Universe could 'help us understand how the cosmic story began', astronomers say. GS-NDG-9422 (9422) was found approximately one billion years after the Big Bang and stood out because it has an odd, never-before-seen light signature -- indicating that its gas is outshining its stars. The 'totally new phenomena' is significant, researchers say, because it could be the missing-link phase of galactic evolution between the Universe's fi

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Most Americans Won't Get Vaccinated as Flu, COVID Season Looms: Survey

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- Most Americans don’t plan to get vaccinated against the flu or COVID-19 this season, a new survey has found.Fewer than two in five U.S. adults (38%) say they will definitely get a flu jab, and only one in four (26%) say.

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Mapping distant planets: 'Ridges', 'deserts' and 'savannahs'

Science Daily: Pharmacology News

Researchers examined Neptunian exoplanets -- these planets share similar characteristics to our own Neptune, but orbit outside of our solar system. Scientists discovered a new area called the 'Neptunian Ridge' -- in between the 'Neptunian desert' and the 'Neptunian Savannah'. A new 'map' of distant planets shows a ridge of planets in deep space, separating a desert of planets from a more populated savannah.

Research 108
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Experimental Nasal Spray Might Ward Off Multiple Viruses

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- A non-drug nasal spray could theoretically help stop the spread of respiratory viruses like the flu and COVID-19 better than wearing a mask, a new study suggests.The spray uses ingredients that are medically inactive to.

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Harvests, wildfires, epidemics: How the jet stream has shaped extreme weather in Europe for centuries

Science Daily: Pharmacology News

Tree-ring data reveal that periodic shifts in strong winds high above the Earth's surface have driven opposite climates in different parts of Europe for the past 700 years and likely much longer, resulting in contrasting patterns in weather, agricultural and societal extremes.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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14.3 Million Americans Are Caring for Ill or Disabled Veteran

Drugs.com

WEDNESDAY, Sept. 24, 2024 -- Millions of Americans are caring for veterans, putting their finances and their mental health on the line to help those who have served the country.More than 14 million Americans now provide daily care to wounded, sick.

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Ice cores show pollution's impact on Arctic atmosphere

Science Daily: Pharmacology News

A new study on ice cores from Alaska and Greenland found that air pollution from the burning of fossil fuels reaches the remote Arctic in amounts large enough to alter its fundamental atmospheric chemistry. The researchers unexpectedly found pollution's footprint in levels of an airborne byproduct of marine phytoplankton activity, which plummeted as soon as widespread fossil fuel usage began in the industrial era.

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Answers Company Recalls Raw Dog Food Due to Salmonella, Listeria Threat

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- A raw diet pet food company is recalling cartons of frozen beef and chicken dog food that could be tainted with salmonella or listeria germs.Answers Pet Food announced the recall this week after the U.S. Food and Drug.

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An Italian biotech gets $52M to advance pediatric gene therapies

BioPharma Drive: Drug Pricing

The financing will support a technology designed to make delivery of lentiviral gene therapies, which are typically administered through a complex process, more convenient.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Most People With Schizophrenia Aren't Getting Treated

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- Only 1 in every 4 U.S. adults struggling with schizophrenia receive "minimally adequate treatment," new data shows.Many of these patients also struggle with other mental health issues, such as substance abuse or.

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Protein behavior can be predicted with simple math

Science Daily: Pharmacology News

Researchers have discovered that mutations affect protein stability following remarkably simple rules. The discovery has profound implications for accelerating the development of new treatments for diseases or the design of new proteins with industrial applications.

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Novo Nordisk CEO Grilled by Congress Over Price of Ozempic

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- During a tense hearing before a Senate committee on Tuesday, Novo Nordisk CEO Lars Fruergaard Jørgensen faced tough questions over the company's high prices for its blockbuster drugs Ozempic and Wegovy.While testifying.

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Encoding human experience: Study reveals how brain cells compute the flow of time

Science Daily: Pharmacology News

A landmark study has begun to unravel one of the fundamental mysteries in neuroscience -- how the human brain encodes and makes sense of the flow of time and experiences.

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988 Mental Health Crisis Calls Now Link to Caller Location, Not Area Code

Drugs.com

WEDNESDAY, SEPT. 25, 2024 -- In a move that could mean more Americans in crisis get help and get it quickly, federal officials announced Tuesday that major cellphone carriers now have the technology to direct 988 callers to local mental health.

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Brazilian fossils reveal jaw-dropping discovery in mammal evolution

Science Daily: Pharmacology News

The discovery of new cynodont fossils from southern Brazil by a team of palaeontologists has led to a significant breakthrough in understanding the evolution of mammals.

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ACR Response Criteria in Rheumatoid Arthritis Clinical Trials

Quanticate

In rheumatoid arthritis (RA) clinical trials, accurately measuring the effectiveness of treatments is critical for determining their value in managing this chronic and debilitating condition. By evaluating improvements in joint symptoms and overall disease activity, the ACR criteria provide a clear and consistent framework for determining the efficacy of RA therapies.

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Mars' missing atmosphere could be hiding in plain sight

Science Daily: Pharmacology News

New research suggests Mars' missing atmosphere -- which dramatically diminished 3.5 billion years ago -- could be locked in the planet's clay-covered crust. Water on Mars could have set off a chain reaction that drew CO2 out of the atmosphere and converted it into methane within clay minerals.

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Initial Symptoms of MS Could Guide Prognosis, Treatment

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- Two key symptoms that can arise soon after a diagnosis of multiple sclerosis (MS) could predict how swiftly the illness will progress and suggest best treatment options, new research shows.The two symptoms -- blurred.

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How special is the Milky Way Galaxy?

Science Daily: Pharmacology News

The SAGA Survey just published three new research articles that provide us with new insights into the uniqueness of our own Milky Way Galaxy after completing the census of 101 satellite systems similar to the Milky Way's.

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Breaking the REMS Barrier: The Fight for Fair Drug Competition

Drug Patent Watch

Generic drug manufacturers face significant challenges when attempting to navigate around REMS (Risk Evaluation and Mitigation Strategies) imposed by brand-name drug companies. These strategies, intended to ensure drug safety, are sometimes misused to delay generic competition.

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Space Travel May Not Be Healthy for Heart Muscle

Drugs.com

WEDNESDAY, Sept. 25, 2024 -- Long-term space travel to Mars could be bad for astronauts’ hearts, a new zero-gravity study shows.After a month at the International Space Station, a set of 48 bioengineered human heart tissue samples beat about half a.

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Drone footage provides new insight into gray whales' acrobatic feeding behavior

Science Daily: Pharmacology News

Drone footage is offering new insight into the acrobatics undertaken by gray whales foraging in the waters off the coast of Oregon.

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BioAge prices $198M IPO, validating pivot to obesity drug research

BioPharma Drive: Drug Pricing

The offering, which was upsized twice, will support development of a drug the company believes can boost the effects of popular weight loss medicines like Eli Lilly’s Zepbound.

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Reconstructing the evolutionary history of the grape family

Science Daily: Pharmacology News

Until now, it was believed that plants of the grape family arrived at the European continent less than 23 million years ago. A study on fossil plants draws a new scenario on the dispersal of the ancestors of grape plants and reveals that these species were already on the territory of Europe some 41 million years ago. The paper describes a new fossil species of the same family, Nekemias mucronata, which allows us to better understand the evolutionary history of this plant group, which inhabited E

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