Fri.Jul 19, 2024

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Waste Styrofoam can now be converted into polymers for electronics

Science Daily: Pharmacology News

A new study describes a chemical reaction that can convert Styrofoam into a high-value conducting polymer known as PEDOT:PSS. Researchers also noted that the upgraded plastic waste can be successfully incorporated into functional electronic devices, including silicon-based hybrid solar cells and organic electrochemical transistors.

Research 121
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Nanoemulsion based lipid nanoparticles for effective demethylcantharidin delivery to cure liver cancer

Chemical Biology and Drug Design

Demethylcantharidin (DEM) is a widely used antitumor drug; however, its poor tumor targeting and serious organotoxicity limit its application. The aim of this study was to develop a new drug delivery system for efficient delivery of DEM. DEM, demethylcalcin; DNLNs, nanoemulsion based lipid nanoparticles containing demethylcantharidin; EPR, enhanced permeability and retention; PEG-400, polyethylene glycol 400.

Drugs 100
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Interrogating a Compound Library in Search of an Inhibitor for TREM-like Transcript-1 to Fibrinogen Binding [Cardiovascular]

ASPET

Cardiovascular disease (CVD) remains one of leading causes of death worldwide. Aberrant platelet function mediate fibrin(ogen) rich thrombi that lead to occlusive thrombi associated with mortality. The receptor, TREM-like transcript-1 (TLT-1), stored in the platelet a-granules and released upon platelet activation, binds fibrinogen and von Willebrand factor.

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New snake discovery rewrites history, points to North America's role in snake evolution

Science Daily: Pharmacology News

A new species of fossil snake unearthed in Wyoming is rewriting our understanding of snake evolution. The discovery, based on four remarkably well-preserved specimens found curled together in a burrow, reveals a new species named Hibernophis breithaupti. This snake lived in North America 34 million years ago and sheds light on the origin and diversification of boas and pythons.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Mechanisms and management of thrombosis in cancer: focus on gastrointestinal malignancies [Minireview]

ASPET

Cancer patients have an increased risk of venous thromboembolism (VTE) which is their second cause of death after disease progression itself. Several thrombotic risk factors coexist in cancer patients, including the ability of both cancer and tumoral microenvironment's cells to directly or indirectly activate platelets and the enzymes of the coagulation cascade, resulting in a hyper-coagulable state of blood.

Therapies 100
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German Patient is 7th Person Probably Cured of HIV

Drugs.com

FRIDAY, July 19, 2024 -- A German man has become the seventh person to apparently be cured of HIV, researchers report.The 60-year-old man, referred to as the “next Berlin Patient,” was treated with a stem cell transplant in October 2015 for acute my.

Research 116

More Trending

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Studies Support Use of Daily Antibiotic to Prevent STDs in High-Risk Groups

Drugs.com

FRIDAY, July 19, 2024 -- It's long been known that popping the antibiotic doxycycline within 72 hours of a risky sexual encounter can greatly reduce a person's risk for a sexually transmitted infection (STI). In fact, the U.S. Centers for Disease.

Disease 116
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An immune factor in the brain plays critical roles in neuron function and aging

Broad Institute

An immune factor in the brain plays critical roles in neuron function and aging By Tom Ulrich July 19, 2024 Breadcrumb Home An immune factor in the brain plays critical roles in neuron function and aging Study highlights unexpected interactions between innate immune system and neurons, raises questions about additional roles for immune system in the brain with aging.

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Ancient Viruses Might Be Spurring Modern-Day Cancers

Drugs.com

FRIDAY, July 19, 2024 -- Cancer growth can be fueled by flecks of ancient viral DNA lodged into the genetics of modern humans, a new study says.Overall, about 8% of the human genome is made of bits of DNA left behind by viruses that infected our.

Virus 111
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InMed’s INM-901 Demonstrates Potential as a Multi-factorial Approach to Treating Alzheimer’s Disease

Fierce BioTech

InMed’s INM-901 Demonstrates Potential as a Multi-factorial Approach to Treating Alzheimer’s Disease jpiatt Fri, 07/19/2024 - 09:56

Disease 124
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Fat Cats Purrfect for Studying Obesity in Humans

Drugs.com

FRIDAY, July 19, 2024 -- Pudgy with a purpose: Fat cats could help humans better understand the way gut bacteria influences conditions like obesity and type 2 diabetes, a new study claims.Food-related changes in obese cats’ gut microbiome have s.

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Lilly alone in bidding for Morphic; Novartis won’t yet file MorphoSys drug

BioPharma Drive: Drug Pricing

Federal filings showed no companies other than Lilly made an offer to buy Morphic, while Novartis executives said they’re still waiting for more data on pelabresib.

Drugs 73
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Dental Veneers: Everything You Need to Know

Drugs.com

FRIDAY, July 19, 2024 -- Looking for a brand new smile?Many people with chipped, worn or indelibly stained teeth may ponder the possibility of veneers. They're wholly cosmetic, typically aren't covered by dental insurance and can cost thousands of.

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Perficient Interviewed for Forrester Report on Manufacturing Operations Management Vision

Perficient: Drug Development

Customers are demanding a personalized experience, and manufacturing is no different. One-size-fits-all manufacturing is now becoming a thing of the past. Today, we are seeing a decline in the mass production of identical products in exchange for personalization and niche products. As consumers intensify their expectations for on-demand personalization and delivery within days of purchase, marketplaces that offer wide ranges of options without sacrificing price or availability, like Amazon, have

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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FDA Allows Marketing of Vuse Tobacco-Flavored Vapes

Drugs.com

FRIDAY, July 19, 2024 -- The U.S. Food and Drug Administration on Thursday authorized the sale of the country's best-selling e-cigarette.The agency's decision only applies to several tobacco-flavored versions of the reusable product, sold as Vuse.

Marketing 105
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New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

Drugs 52
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Mushroom Gummies That Sickened Users Contained Illicit Psilocybin

Drugs.com

FRIDAY, July 19, 2024 -- Mushroom gummies being sold to promote brain function might instead contain harmful ingredients not listed on the label, including illicit psilocybin, the hallucinogen found in “magic” mushrooms, experts warn in new rep.

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Sloane’s 2nd ASO Dose

KIF1A

Megan, Sloane’s mom, writes: Hello KAND Families! Sloane received her second ASO dose on June 6th. We were still in New York City. On the 5th we had her predose blood draws and her research EEG (the PT had a conflict so we had to move that to the 10th but typically there would also be a PT eval predose). Post dose on the 6th we were monitored in a recovery room and then moved to our overnight room.

Doctors 52
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Too Many Breast Cancer Survivors Miss Out on Genetic Screening

Drugs.com

FRIDAY, July 19, 2024 -- Many breast cancer patients aren’t getting genetic counseling and testing that could help them get the most effective treatment, a new study finds.Only three-quarters of patients eligible for genetic testing after their b.

Treatment 105
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Optimizing Product Commercialization in Today’s IDN Environment

Drug Channels

Today’s guest post comes from Greg Skalicky, President, EVERSANA; Krista Pinto, President, Deployment Solutions, EVERSANA; and Faruk Abdullah, President, Professional Services & Chief Business Officer, EVERSANA Greg, Krista, and Faruk explain how and why integrated delivery networks (IDNs) have become crucial stakeholders for drug commercialization.

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One Emotion Drives Teens to Scroll Through Instagram

Drugs.com

FRIDAY, July 19, 2024 -- Boredom is the key emotion behind most teens’ use of Instagram, a new study says.Teens open the app because they’re bored, then sift through its contents looking for interesting bits to relieve their boredom, researchers rep.

Research 102
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Global tech outage hits US hospitals

BioPharma Drive: Drug Pricing

At least 11 health systems were experiencing issues Friday after an update by cybersecurity firm CrowdStrike went awry.

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Current Gene Screens Miss Many at High Cancer Risk: Study

Drugs.com

THURSDAY, July 19, 2024 -- As good as many genetic tests might be, a deeper look at the DNA of over 44,000 people identified many who carried genes that hike their risks for cancer, researchers said."This study is a wake-up call, showing us that.

DNA 59
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New patent expiration for Nalpropion drug CONTRAVE

Drug Patent Watch

Annual Drug Patent Expirations for CONTRAVE Contrave is a drug marketed by Nalpropion and is included in one NDA. It is available from one supplier.

Drugs 52
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Which pharmaceutical companies have the most pellets dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most pellets dosed drugs. For a different perspective, see the most popular dosage types.