Tue.Jul 16, 2024

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Scientists develop new artificial intelligence method to create material 'fingerprints'

Science Daily: Pharmacology News

Researchers have developed a new technique that pairs artificial intelligence and X-ray science.

Science 344
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Hormone Therapy for Breast Cancer May Lower Dementia Risk

Drugs.com

TUESDAY, July 16, 2024 -- Hormone therapy for breast cancer might reduce a woman’s later risk of dementia and Alzheimer’s disease, a new study finds.Overall, hormone therapy is associated with a 7% lower risk of developing Alzheimer’s or a related d.

Therapies 278
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Scientists find that small regions of the brain can take micro-naps while the rest of the brain is awake and vice versa

Science Daily: Pharmacology News

For the first time, scientists have found that sleep can be detected by patterns of neuronal activity just milliseconds long, 1000 times shorter than a second, revealing a new way to study and understand the basic brain wave patterns that govern consciousness.

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Sionna revives AbbVie’s cystic fibrosis drugs, eyeing a shot at Vertex

BioPharma Drive: Drug Pricing

The well-funded startup says drugs AbbVie abandoned last year could form a combination regimen with “superior efficacy” to Vertex’s market-leading medicines.

Drugs 273
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Bizarre 'garden sprinkler-like' jet is spotted shooting out of neutron star

Science Daily: Pharmacology News

A strange 'garden sprinkler-like' jet coming from a neutron star has been pictured for the first time. The S-shaped structure is created as the jet changes direction due to the wobbling of the disc of hot gas around the star -- a process called precession, which has been observed with black holes but, until now, never with neutron stars.

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Ancient microbes offer clues to how complex life evolved

Science Daily: Pharmacology News

Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.

Virus 307
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Parents, Take Note: Survey Shows Teens Need More Support Than They Get

Drugs.com

TUESDAY, July 16, 2024 -- As millions of American teens continue to struggle with their mental health, a new survey reveals a sizable gap between how much support teens say they get and how much support their parents think they are getting. In the.

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How astronomers are using pulsars to observe evidence of dark matter

Science Daily: Pharmacology News

Tantalizing evidence of potential dark matter objects has been detected with the help of the Universe's 'timekeepers'. These pulsars -- neutron stars which rotate and emit lighthouse-like beams of radio waves that rapidly sweep through space -- were used to identify mysterious hidden masses. Pulsars earned their nickname because they send out electromagnetic radiation at very regular intervals, ranging from milliseconds to seconds, making them extremely accurate timekeepers.

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How to Predict Who Will Respond to Glaucoma Treatment -- and Who Won't

Drugs.com

TUESDAY, July 16, 2024 -- An experimental blood test might be able to predict whether glaucoma patients will continue to lose their vision following treatment, researchers report.A biochemical called nicotinamide adenine dinucleotide (NAD) tends to.

Treatment 246
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New analysis of Cassini data yields insights into Titan's seas

Science Daily: Pharmacology News

A new study of radar experiment data from the Cassini-Huygens mission to Saturn has yielded fresh insights related to the makeup and activity of the liquid hydrocarbon seas near the north pole of Titan, the largest of Saturn's 146 known moons.

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Could Living in Poor Neighborhoods Fuel Prostate Cancer in Black Men? Study Says It Might

Drugs.com

TUESDAY, July 16, 2024 -- The stress of living in a poor neighborhood might contribute to higher rates of aggressive prostate cancer in Black men, a new study warns.Black men are more than twice as likely to die from prostate cancer than white men.

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Nature-based solutions to disaster risk from climate change are cost effective

Science Daily: Pharmacology News

A new global assessment of scientific literature finds that nature-based solutions (NbS) are an economically effective method to mitigate risks from a range of disasters -- from floods and hurricanes to heatwaves and landslides -- which are only expected to intensify as Earth continues to warm.

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Vertex sues US over limits on providing fertility services to Casgevy patients

BioPharma Drive: Drug Pricing

In the suit, Vertex argues HHS’ stance forces a “Hobson’s choice” on people with sickle cell seeking to undergo the potentially curative treatment.

Treatment 183
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Sun-like stars found orbiting hidden companions

Science Daily: Pharmacology News

Astronomers have uncovered what appear to be 21 neutron stars in orbit around stars like our Sun. The discovery is surprising because it is not clear how a star that exploded winds up next to a star like our Sun.

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Asceneuron raises another $100M for Alzheimer’s drug development

BioPharma Drive: Drug Pricing

The Merck KGaA spinout has a tau-regulating medicine it claims could be an “ideal therapy” for Alzheimer’s. The pitch has intrigued both healthcare investors and pharma venture arms.

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How Early Antibiotic Use Could Raise Kids' Asthma Risk

Drugs.com

TUESDAY, July 16, 2024 -- Early exposure to antibiotics might increase a kid’s risk of asthma by altering their gut bacteria, a new mouse study finds.Antibiotics could specifically lower gut production of indole propionic acid (IPA), a biochemical t.

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Cardurion raises another $260M to fuel heart drug pipeline

BioPharma Drive: Drug Pricing

The financing, which ranks as one of the year’s larger private rounds, will help the startup advance a pair of drugs and potentially acquire other medicines.

Drugs 148
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Safe Pregnancies Possible After Stem Cell Treatment for Blood Cancer

Drugs.com

TUESDAY, July 16, 2024 -- Women who've undergone stem cell treatments for blood cancers, or for illnesses such as sickle cell disease, can successfully bring a pregnancy to term, new research shows.The German findings run counter to the perceived.

Treatment 130
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Vertex taps Orum to hunt for better ‘preconditioning’ drugs

BioPharma Drive: Drug Pricing

The deal gives Vertex rights to use Orum’s ADC-like technology to discover gentler preparatory regimens for patients receiving intensive treatments like Casgevy.

Treatment 148
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U.S. Stroke Survival Is Improving, But Race Still Plays Role

Drugs.com

TUESDAY, July 16, 2024 -- There's good news and bad for stroke survival in the United States: New research shows that Americans are now more likely to survive long-term, but that's more true for whites than for Black Americans.At least for a sample.

Research 130
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Navigating Patent Opposition in Drug Patenting: A Comprehensive Guide

Drug Patent Watch

Introduction Patent oppositions are a crucial tool in the pharmaceutical industry, allowing civil society to challenge the validity of patents […] Source

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Blood Test Shows Promise in Spotting Preeclampsia Before Symptoms Surface

Drugs.com

TUESDAY, July 16, 2024 -- An experimental blood test could help detect pregnant women at increased risk for preeclampsia, a serious high blood pressure condition that can harm both mother and child.Researchers report the test looks at genetic.

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Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation

Chemical Biology and Drug Design

This study provides preliminary elucidation of multiple pharmacological targets, biological processes and signaling pathways of VD against TC. These findings offer valuable insights for future therapeutic strategies targeting TC. Abstract Thyroid cancer (TC) is one of the most common endocrine malignancies worldwide. Increasing evidence suggests that vitamin D (VD) has potential benefits in the treatment of TC.

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Long COVID Rates Are Expected to Decline: Study

Drugs.com

TUESDAY, July 16, 2024 -- People's odds for Long COVID appear to be declining with the advent of new variants of the virus, along with repeat infections and vaccinations, new research shows.That suggests that the average person's chances of.

Virus 130
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Therapeutic potential and recent progression of BTK inhibitors against rheumatoid arthritis

Chemical Biology and Drug Design

Several Bruton's tyrosine kinase (BTK) inhibitors have been shown in studies to be effective in the inhibition of biological activity analysis and in animal models. This review focuses on the BTK inhibition mechanism and its possible impact on immune-mediated disease, as well as the types being investigated for RA, preclinical and clinical investigations and future research opportunities.

Disease 100
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Expert Interpretation and Analysis of Regulatory Intelligence Are Key to FSP-Delivered Pharmacovigilance

PPD

Our recent white paper explores the many ways in which a functional service provider (FSP) engagement delivers key pharmacovigilance (PV) capabilities necessary across the product life span and across different geographical regions. Many pharma, biotech and medical device companies rely on FSP partnerships for comprehensive and cost-effective PV regulatory intelligence (RI), including: Monitoring for changes Analyzing and interpreting regulations and guidance Communicating requirements and opera