Drug Discovery World

JUNE 17, 2024

Charles River Laboratories International has opened a new Charles River Accelerator and Development Lab (CRADL) facility on Chestnut Street in Somerville, Massachusetts, an emerging life sciences hub. The facility is co-located with Nest.Bio, a provider of rentable BSL-2 laboratory and office space. The Chestnut Street location will address an increased demand for more flexible vivarium and bench space, as well as on-demand in vivo study support services within the heart of Massachusetts’

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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Disease Therapies Trials 139

Drug Discovery World

JUNE 17, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With a lead story on the restoration of congenital hearing loss following gene therapy, the news highlights selection this week focuses on cell and gene therapies (CGT) and genetics, particularly some key progress in relation to CAR-T therapies.

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Therapies Drugs 148

Science Daily: Pharmacology News

JUNE 17, 2024

New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.

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Research 134

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

JUNE 17, 2024

The Analytical Laboratory Robotics Topic group of euRobotics has released the next iteration of the roadmap for Analytical Laboratory Robotics in Europe. It is entitled ‘Research roadmap for laboratory community-automating discovery: high throughput experimentation, diagnostics and robotics/AI’. The roadmap will be formally launched during the Future Labs Live 2025 event at the Congress Centre Basel on Thursday 27 June at 15:45-16:15 (Room Kairo).

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Laboratories Science Research Marketing 148

Science Daily: Pharmacology News

JUNE 17, 2024

The relationship between mother and child may offer clues to the mystery of why humans live longer than expected for their size -- and shed new light on what it means to be human -- according to a new study.

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Science Daily: Pharmacology News

JUNE 17, 2024

One in four parents describe getting their young child to bed as difficult -- and these parents are less likely to have a bedtime routine, more likely to leave on a video or TV show, and more likely to stay with their child until they're asleep.

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Drug Discovery World

JUNE 17, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With a lead story on the restoration of congenital hearing loss following gene therapy, the news highlights selection this week focuses on cell and gene therapies (CGT) and genetics, particularly some key progress in relation to CAR-T therapies.

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Therapies Drugs 130

Science Daily: Pharmacology News

JUNE 17, 2024

Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.

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Research 118

Drug Patent Watch

JUNE 17, 2024

The article “The devil is in the divisional: an analysis of divisional patents, deadlines, declarations and suggestions for future practice” by Mieke Filler provides a comprehensive analysis of the strategic use of divisional patents in the pharmaceutical sector to delay generic and biosimilar market entry.

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Biosimilars Pharmaceuticals Marketing 110

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Clinical Trials

Science Daily: Pharmacology News

JUNE 17, 2024

An international team of scientists has identified the oldest fossil of a sea-going reptile from the Southern Hemisphere -- a nothosaur vertebra found on New Zealand's South Island. 246 million years ago, at the beginning of the Age of Dinosaurs, New Zealand was located on the southern polar coast of a vast super-ocean called Panthalassa. 'The nothosaur found in New Zealand is over 40 million years older than the previously oldest known sauropterygian fossils from the Southern Hemisphere.

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International 117

BioPharma Drive: Drug Pricing

JUNE 17, 2024

One biotech executive called the Supreme Court’s decision a “very important win” for the industry, although new challenges to the FDA’s regulation of the drug could still be forthcoming.

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FDA Regulations Drugs 107

Science Daily: Pharmacology News

JUNE 17, 2024

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Researchers propose the concept of a 'protein aggregation clock' to measure aging and health.

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Disease Research 115

Drug Patent Watch

JUNE 17, 2024

Pharmaceutical companies employ various strategies to extend the commercial life and patent protection of successful drugs. Here are some key approaches with examples: New Formulations One common strategy is to develop and patent new formulations of the existing drug compound to provide benefits like reduced dosing frequency, easier administration, improved bioavailability, or reduced side effects.

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Pharmaceutical Companies Drugs Pharmaceuticals 105

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Clinical Trials

Science Daily: Pharmacology News

JUNE 17, 2024

A study on the remains of the Chaves and Puyascada caves, both located in the province of Huesca, Spain, yields the first direct proof of the consumption and processing of dairy products in the Pyrenees already at the start of the Neolithic period, approximately 7,500 years ago, as well as the consumption of pig. The results lead to doubts about the belief that these products were first used much later in the Pyrenean mountain range.

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Production 111

Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- The U.S. Surgeon General announced Monday that he will push for warning labels on all social media platforms, stating that they may harm teens' mental health."The mental health crisis among young people is an emergency --.

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Science Daily: Pharmacology News

JUNE 17, 2024

A team of scientists used NASA's James Webb Space Telescope to parse the composition of the Crab Nebula, a supernova remnant located 6,500 light-years away in the constellation Taurus.

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Drug Patent Watch

JUNE 17, 2024

A recent whitepaper by Hermann Mucke summarizes the steps to performing an FTO for drug repurposing: Overview An FtO analysis determines if a new product or process can proceed without infringing third-party intellectual property (IP) rights, especially patents. It is crucial for drug repurposing projects involving known compounds that may still be patent-protected.

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Drugs Production 104

Science Daily: Pharmacology News

JUNE 17, 2024

Astronomers have discovered a double-record-breaking pair of quasars. Not only are they the most distant pair of merging quasars ever found, but also the only pair confirmed in the bygone era of the Universe's earliest formation.

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Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- Depression can be sorted into six distinct types using brain scans, a revelation that could improve treatment for many suffering the debilitating mood disorder.Researchers analyzed brain scans to identify six different.

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Treatment 98

Science Daily: Pharmacology News

JUNE 17, 2024

In a breakthrough discovery that challenges the conventional understanding of cosmology, scientists have unearthed new evidence that could reshape our perception of the cosmos. New research shows that rotation curves of galaxies stay flat indefinitely far out, corroborating predictions of modified gravity theory as an alternative to dark matter.

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Research 108

Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- Genetics can play a role in a person's odds for Alzheimer's disease, and new research suggests differences in that risk are based on which parent had the illness.In a study of 4,400 people still "cognitively unimpaired,".

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Disease Research 98

Science Daily: Pharmacology News

JUNE 17, 2024

Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects.

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Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- Lizards called bearded dragons may not breathe fire, but they can be a source of one nasty infection: Salmonella.So warned the U.S. Centers for Disease Control and Prevention in a health advisory on Friday, noting there.

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Disease 98

NIOSH Science Blog: Drugs

JUNE 17, 2024

Building strategic partnerships can create solutions to large community safety issues High-risk buildings can be abandoned or condemned structures. These buildings pose hazards to firefighters and communities. This is because many are structurally unsound and not safe for any person to enter. These buildings are commonly a key contributing factor to firefighter line of duty deaths, noted in NIOSH firefighter fatality investigations.

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Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- Exercising in natural surroundings -- a jog through a park, a bicycle ride along a trail -- could be more beneficial than working out indoors, a new review suggests.However, access to natural areas that are public varies.

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

The new company, Spur Therapeutics, is getting another $50 million from Syncona to support its broadened pipeline, which targets Parkinson’s disease as well as heart conditions.

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Treatment Therapies Disease 97

Science Daily: Pharmacology News

JUNE 17, 2024

A major earthquake 2,500 years ago caused one of the largest rivers on Earth to abruptly change course, according to a new study. The previously undocumented quake rerouted the main channel of the Ganges River in what is now densely populated Bangladesh, which remains vulnerable to big quakes.

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

Elevate precision medicine: dose optimization and immune monitoring through advanced liquid biopsies.

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Clinical Trials RNA Trials 109

Drugs.com

JUNE 17, 2024

MONDAY, June 17, 2024 -- Nicotine pouches might be less harmful than smoking or chewing tobacco, but they still pose an addiction risk to users, a new review finds.These pouches are filled with crystallized nicotine, and are placed between the gums.

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

Called soticlestat, the drug had seemed promising in earlier studies for people with Dravet and Lennox-Gastaut syndrome, enough to persuade Takeda to take on full rights to the drug.

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Trials Drugs 62

Drug Patent Watch

JUNE 17, 2024

Annual Drug Patent Expirations for TPOXX Tpoxx is a drug marketed by Siga Technologies and is included in two NDAs. It is available from one supplier. There are ten patents protecting this drug. This drug has ninety-one patent family members in twenty-three countries. The generic ingredient in TPOXX is tecovirimat.

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Drugs Marketing 59

BioPharma Drive: Drug Pricing

JUNE 17, 2024

Research shows that 20% of patients have failed to fill a script in the past, and one-third aren’t confident managing their illness. Engaging patients as soon as a medicine is prescribed can help.

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Research 62

Drug Patent Watch

JUNE 17, 2024

Annual Drug Patent Expirations for NUVIGIL Nuvigil is a drug marketed by Cephalon and is included in one NDA. It is available from seven suppliers. There are two patents protecting this drug and two Paragraph IV challenges. NUVIGIL drug price trends. Drug patent litigation for NUVIGIL. The generic ingredient in NUVIGIL is armodafinil.

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