Drug Discovery World

NOVEMBER 21, 2023

Biotechnology company bit.bio has launched a range of immune cells to provide researchers with a consistently functional and rapid human in vitro model for the study of neuroinflammation and neurodegenerative diseases. The company’s ioMicroglia cell range is designed to recapitulate key human microglia functions and as such, can mediate inflammatory responses, dispose of unwanted materials, and carry out immune surveillance.

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

Recent research has shown that engravings in a cave in La Roche-Cotard (France), which has been sealed for thousands of years, were actually made by Neanderthals. The findings reveal that the Neanderthals were the first humans with an appreciation of art.

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Research 142

Drug Discovery World

NOVEMBER 21, 2023

Fosun Pharma USA and Treehill Partners have formed a jointly operating vehicle for investment in clinical stage assets. The new business will be looking for high-quality, mid- to late-stage assets, clinically focused on the US market. There will also be a focus on high quality non-US clinical stage biopharma assets seeking to access the US market.

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Chemical Biology and Drug Design

NOVEMBER 21, 2023

SNX10 shRNA expression was transfected into AGS cells, and Rop intervention was given. qRT-PCR, CCK8, wound healing assay, transwell assay, and western blot were used to clarify the effects of Rop on the proliferation and metastasis of SNX10/SRC/STAT3 pathway in gastric cancer cells. Our results suggest that Rop shows a potential role in preventing proliferation and metastasis of gastric cancer.

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Treatment Research 100

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2023

The partnership is another investment by the biotech subsidiary in artificial intelligence for drug discovery and development, continuing an industry trend.

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Drugs 130

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 -- Biologic drugs to treat asthma have been around for two decades, but a surprising number of family doctors still aren’t prescribing them to kids and adults. A new survey found that more than two in five primary care.

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Doctors Drugs 119

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 -- Peaches, nectarines and plums tainted with Listeria have caused one death and put 10 people in the hospital with food poisoning across seven states, federal officials say. The Listeria outbreak also has caused one.

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Hospitals 116

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2023

Studying somatic mutations could be “the next wave of opportunity” to develop more precise medicines, said Mike Stratton, one of Quotient’s scientific co-founders.

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

When bacteria build communities, they cooperate and share nutrients across generations. Researchers have been able to demonstrate this for the first time using a newly developed method. This innovative technique enables the tracking of gene expression during the development of bacterial communities over space and time.

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Research 112

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 -- Nearly half of Americans have never heard of health-threatening PFAS “forever chemicals,” a new survey has found. PFAS (perfluoroalkyl and polyfluoroalkyl substances) are a category of thousands of manufactured.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2023

Surging demand for GLP-1 agonists has put medtech firms like Medtronic under pressure, even as they argue the hit to their businesses will be minimal.

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Drugs 109

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 — A year after suffering a concussion, teens, especially boys, are more likely than their peers to think about, plan and even attempt suicide, new research finds. With more concussions, the risk grows. Teen boys.

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Research 104

Science Daily: Pharmacology News

NOVEMBER 21, 2023

Contrary to the commonly-held view, the brain does not have the ability to rewire itself to compensate for the loss of sight, an amputation or stroke, for example, say scientists. The researchers argue that the notion that the brain, in response to injury or deficit, can reorganize itself and repurpose particular regions for new functions, is fundamentally flawed -- despite being commonly cited in scientific textbooks.

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Research 105

Fierce BioTech

NOVEMBER 21, 2023

Cell and Gene Therapy (CGT) has the potential to transform the life trajectory of children with genetic conditions amendable to gene modification with advances in treatment and possible cures. | Pediatric CGT trials have the potential to cure diseases and prolong lives. Discover steps to protect safety and enhance operations in your CGT trials.

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Therapies Research Trials Treatment 91

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 21, 2023

In 2020 and 2021, California experienced fire activity unlike anything recorded in the modern record. When the smoke cleared, the amount of burned forest totaled ten times more than the annual average going back to the late 1800s. We know that wildlife in western forests evolved with changing habitat and disturbances like wildfire. Each species responds differently, some benefiting from openings, others losing critical habitat.

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SCIENMAG: Medicine & Health

NOVEMBER 21, 2023

NATIONAL HEART CENTRE SINGAPORE PARTNERS MEDERA’S NOVOHEART TO DEVELOP ASIA’S FIRST BIOENGINEERED HUMAN HEART-IN-A-JAR WITH HEART FAILURE FOR PRECISION MEDICINE Credit: National Heart Centre Singapore NATIONAL HEART CENTRE SINGAPORE PARTNERS MEDERA’S NOVOHEART TO DEVELOP ASIA’S FIRST BIOENGINEERED HUMAN HEART-IN-A-JAR WITH HEART FAILURE FOR PRECISION MEDICINE SINGAPORE/ BOSTON, MASSACHUSETTS, UNITED STATES, 21 November 2023 – National […]

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

Despite public perception, the Antarctic ozone hole has been remarkably massive and long-lived over the past four years; researchers believe chlorofluorocarbons (CFCs) aren't the only things to blame.

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Research 82

SCIENMAG: Medicine & Health

NOVEMBER 21, 2023

Associate Professor of physics Benjamin Jones has received a $341,571 grant from the U.S. Department of Energy to continue his successful traineeship program at The University of Texas at Arlington. Credit: University of Texas at Arlington Associate Professor of physics Benjamin Jones has received a $341,571 grant from the U.S.

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Research 89

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 -- If you belong to one of the 46 million American households with a cat, you already know how stressful a trip to the vet can be for your feline -- and you. Rescue might be on the way: The U.S. Food and Drug Administration.

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FDA Drugs 85

SCIENMAG: Medicine & Health

NOVEMBER 21, 2023

Mount Sinai Health System announced that Brendan Carr, MD, MA, MS, a nationally recognized leader in academic medicine and health policy, will be its next Chief Executive Officer.

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

If you look at massive galaxies teeming with stars, you might be forgiven in thinking they are star factories, churning out brilliant balls of gas. But actually, less evolved dwarf galaxies have bigger regions of star factories, with higher rates of star formation. Now, University of Michigan researchers have discovered the reason underlying this: These galaxies enjoy a 10-million-year delay in blowing out the gas cluttering up their environments.

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Research 83

SCIENMAG: Medicine & Health

NOVEMBER 21, 2023

MOSCOW, Idaho (November 21, 2023): A recently published study[i] in Nutrients, an open-access peer-reviewed scientific journal, demonstrates that exchanging pulses for small amounts of typical protein sources and refined grains significantly improves the nutritional profile of the American diet.

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Research 82

Science Daily: Pharmacology News

NOVEMBER 21, 2023

Ten newly discovered species of trilobites, hidden for 490 million years in a little-studied part of Thailand, could be the missing pieces in an intricate puzzle of ancient world geography.

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National Drug & Alcohol Research Centre Blog

NOVEMBER 21, 2023

Olivia Price The reviews are in! “ ★★★★★ – it was a pleasure to see the NDARC PhD candidates and early career researchers do us proud” – Shane Darke, Professor “ ★★★★★ – it was a fantastic experience to learn from a diverse range of speakers and leaders in the alcohol and other drug space; APSAD inspired me to continue working in this field on contemporary challenges that are rising” – Lily Palmer, Research Officer and First Time APSAD Attendee “ ★★★★★ – my favourite APSAD so far” – Michael Farr

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Clinical Trials Trials Doctors Research 72

Science Daily: Pharmacology News

NOVEMBER 21, 2023

Eating more ultra-processed foods (UPFs) may be associated with a higher risk of developing cancers of upper aerodigestive tract (including the mouth, throat and esophagus), according to a new study. The authors of this international study, which analyzed diet and lifestyle data on 450,111 adults who were followed for approximately 14 years, say obesity associated with the consumption of UPFs may not be the only factor to blame.

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International 80

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2023

In a deal worth up to $610 million, Merck will gain a pipeline of neuroscience and rare disease programs from a startup it previously backed.

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Disease 76

Science Daily: Pharmacology News

NOVEMBER 21, 2023

The latest image from NASA's James Webb Space Telescope shows a portion of the dense center of our galaxy in unprecedented detail, including never-before-seen features astronomers have yet to explain. The star-forming region, named Sagittarius C (Sgr C), is about 300 light-years from the Milky Way's central supermassive black hole, Sagittarius A*.

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H1 Blog

NOVEMBER 21, 2023

The life sciences industry, characterized by stringent regulations, vast data sets, and the critical nature of its decisions, is increasingly turning to Artificial Intelligence (AI) for solutions. AI has the potential to revolutionize drug discovery, clinical trials, and personalized medicine. However, before integrating an AI product into a life sciences workflow , it is crucial to evaluate its effectiveness and reliability rigorously.

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Production Science Clinical Trials Regulations 64

Science Daily: Pharmacology News

NOVEMBER 21, 2023

Babies as young as four months old can make sense of how their bodies interact with the space around them, according to new research.

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Research 83

Drugs.com

NOVEMBER 21, 2023

WEDNESDAY, Nov. 22, 2023 -- Countless corks will pop and wine will flow freely during the upcoming holiday season, but some people will pay a price for even the slightest bit of revelry. For those unlucky folks, drinking red wine even in small.

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

A ground-breaking new discovery could transform the way astronomers understand some of the biggest and most common stars in the Universe. Research by PhD student Jonathan Dodd and Professor René Oudmaijer, from the University's School of Physics and Astronomy, points to intriguing new evidence that massive Be stars -- until now mainly thought to exist in double stars -- could in fact be 'triples'.

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Research 68

Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 — University of Louisville researchers say they've developed an artificial intelligence (AI) system with a near-perfect record of diagnosing autism in toddlers. Using specialized MRI scans of the brain, the tool.

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Research 59

Drug Patent Watch

NOVEMBER 21, 2023

Annual Drug Patent Expirations for RUBRACA Rubraca is a drug marketed by Zr Pharma and is included in one NDA. It is available from two suppliers. There are twelve patents… The post New patent expiration for Zr Pharma drug RUBRACA appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs Marketing 59

Fierce BioTech

NOVEMBER 21, 2023

The Contract Transformation of the Biotech and BioPharma Industry swheeler Tue, 11/21/2023 - 18:43 Tue, 12/19/2023 - 12:00 Resource Type Webinar Angelina Bellanton Simon Jones Duration 60 minutes Either you want to implement a CLM, or you don’t know how to fix the processes of the one you have in place. Either is a tough place to be in. Join us in this webinar to learn from a CLM solution implementation expert in the highly regulated field of pharmaceuticals.

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