Drug Discovery World

AUGUST 14, 2023

Research partners in the UK are progressing their orally available small molecule cancer immunotherapy drug into clinical development as a treatment for advanced solid tumours. Sosei Group and Cancer Research UK announced that the first patient has been dosed in a Phase I/IIa clinical trial evaluating Sosei Heptares’ immunotherapy drug HTL0039732. HTL0039732 works by blocking signalling through a specific type of prostaglandin receptor, the prostaglandin E2 (PGE2)-type prostanoid receptor 4 (EP4

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National Institute on Drug Abuse: Nora's Blog

AUGUST 14, 2023

Innovative projects answer NIDA’s challenge to implement substance use prevention in primary care astewart Mon, 08/14/2023 - 10:04 Nora's Blog August 22, 2023 Image ©Getty Images/ Maskot With nearly 110,000 people dying from drug overdoses last year, the crisis has not abated. We have effective treatments for opioid and other drug use disorders, but growing numbers of people are dying from fentanyl even in the absence of a substance use disorder—for instance, young people overdosing on fentanyl-

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Drug Discovery World

AUGUST 14, 2023

The FDA has granted accelerated approval to Janssen’s talquetamab-tgvs (Talvey) for adults with relapsed or refractory multiple myeloma. It has been approved in patients who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody. Talquetamab is a bispecific T cell engaging antibody that binds to the CD3 receptor on the surface of T cells and G protein-coupled receptor class C group 5 member D (GPRC5D)

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BioPharma Drive: Drug Pricing

AUGUST 14, 2023

Elrexfio is the third bispecific antibody cleared to treat the blood cancer, and will compete with other therapies that target the “BCMA” protein on myeloma cells.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

AUGUST 14, 2023

Lung-I Cheng, Vice President and Head of Cell & Gene Therapy Service Line at AmerisourceBergen, and Cori Gorman, Senior Director of CMC and Regulatory Affairs at Biopharma Excellence, offer advice on navigating the different and sometimes contradictory regulatory requirements in the US and EU. Over the past few decades, the incredible progress in personalised medicine has led to the development of life-saving cell and gene therapies (CGT).

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Marketing DNA Therapies FDA 130

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- For people with severe alcohol use disorder, a new gene therapy trial could lead to an effective treatment that would involve chemically rebalancing the area of the brain associated with addiction. “With alcohol.

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Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- As cannabis use has become legal in many U.S. states for medical or recreational use, Americans' views on the drug may have gotten rosier. In fact, a new report finds that over 44% of adults now believe smoking weed each day.

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Drugs 98

Drug Discovery World

AUGUST 14, 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The news headlines this week reflect the level of interest in cell & gene therapies (CGT) in the sector, particularly CAR-T, but also the importance of research collaborations to bring these therapies to patients.

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Therapies Treatment Marketing Research 130

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- Some menstrual products -- pads, tampons, cups and underwear -- contain harmful “forever chemicals,” according to new research into the contents of these essential items. Researchers analyzed more than 100.

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Production Research 98

Drug Discovery World

AUGUST 14, 2023

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The news headlines this week reflect the level of interest in cell & gene therapies (CGT) in the sector, particularly CAR-T, but also the importance of research collaborations to bring these therapies to patients.

Therapies 130

Therapies Treatment Marketing Research 130

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Clinical Trials

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- As cannabis use has become legal in many U.S. states for medical or recreational use, Americans' views on the drug may have gotten rosier. In fact, a new report finds that over 44% of adults now believe smoking weed each.

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Drugs 98

Drug Discovery World

AUGUST 14, 2023

Janssen’s Akeega (niraparib and abiraterone acetate) is now available in the US for adult patients with deleterious or suspected deleterious BRCA-positive metastatic castration-resistant prostate cancer (mCRPC) following FDA approval. It is the first dual action tablet combining a PARP inhibitor with abiraterone acetate, given with prednisone, to be approved in this indication.

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FDA Approval FDA Treatment Disease 130

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- Psilocybin, the active ingredient in "magic" mushrooms, is getting renewed interest as a potential treatment for various health conditions. Now, a new research review argues that migraines should be added to that.

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Perficient: Drug Development

AUGUST 14, 2023

Ready for your Google Optimize sunset replacement? Strategies for Seamless Migration and Accelerated Experimentation Growth The upcoming Google Optimize sunset has made it crucial for businesses to find reliable replacements. In today’s data-driven environment, the functionality of data experimentation tools is paramount. Relying on A/B testing tools for measuring and enhancing website optimization is key to increasing user satisfaction and conversion rates.

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Packaging Marketing Trials Production 98

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 (American Heart Association News) -- Traditionally, many decisions about medical treatment were left up to doctors: They decided, and patients agreed. Today, health care professionals are embracing the idea of shared.

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BioPharma Drive: Drug Pricing

AUGUST 14, 2023

Stephen Apps discusses how technology can help improve the speed and quality of clinical research and why a dedicated, cross-functional approach is needed to maximize its value for smaller biotechs.

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Drug Development Clinical Research Research Drugs 98

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- For people with severe alcohol use disorder, a new gene therapy trial could lead to an effective treatment that would involve chemically rebalancing the area of the brain associated with addiction.

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Therapies Trials Treatment 98

Perficient: Drug Development

AUGUST 14, 2023

Introduction: APIs (Application Programming Interfaces) indeed play a crucial role in modern software development, enabling different applications to interact and exchange data seamlessly. In the contemporary world of technology, APIs have evolved into the fundamental backbone of modern software businesses, serving as the essential means of communication and data exchange between various applications.

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Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- If you’re moving into a home where smokers lived, the first thing you should do to protect your lungs is rip out any old carpeting, new research suggests. Scientists found that tobacco smoke clings to carpet fibers long.

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Research 98

SCIENMAG: Medicine & Health

AUGUST 14, 2023

A collaboration led by UCLA and the Seattle Children’s Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

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Production Research 94

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- The federal government recently stopped pandemic-related emergency food aid, leaving perhaps 2 million more Americans without enough to eat. Emergency allotments in the Supplemental Nutrition Assistance Program (SNAP), also.

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Government 98

Science Daily: Pharmacology News

AUGUST 14, 2023

Imagine using insects as a source of chemicals to make plastics that can biodegrade later -- with the help of that very same type of bug. That concept is closer to reality than you might expect. Researchers will describe their progress to date, including the isolation and purification of the insect-derived chemicals and their conversion into their bioplastics.

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Research 92

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- A more personalized approach to exercise may be necessary, claims a new study that found fat burning varied widely between individuals. Even worse, this rate often does not align with the “fat-burning zone” on commercial.

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SCIENMAG: Medicine & Health

AUGUST 14, 2023

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at the Department of Energy’s Oak Ridge National Laboratory are now turning their drug design approach toward cancer. Credit: Credit: Jill Hemman/ORNL, U.S. Dept.

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Laboratories Treatment Research Drugs 89

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 – The U.S. Food and Drug Administration has warned that consumers should not use certain pregnancy, ovulation, urine, UTI and breast milk test kits over concerns that the tests may not be safe and effective. The tests in.

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FDA Drugs 98

SCIENMAG: Medicine & Health

AUGUST 14, 2023

BATON ROUGE – The Louisiana Obesity Society hosted its inaugural conference, in conjunction with the Louisiana Chapter of American Society of Metabolic and Bariatric Surgery, on Aug. 12 in New Orleans.

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Science 88

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 – The family of Henrietta Lacks has filed another in a series of planned lawsuits over the use of Lacks’ cells without her knowledge or consent. Known as the HeLa cell line, it has changed modern medicine because of the.

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SCIENMAG: Medicine & Health

AUGUST 14, 2023

Unexpected new insights into how COVID-19 infects cells may help explain why coronaviruses are so good at jumping from species to species and will help scientists better predict how COVID-19 will evolve.

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Engineering 86

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- Punishing heat is a fact of life inside America’s prisons without air conditioning, and it is taking a serious toll on prisoners' mental health. When the outside thermometer hits 90 degrees Fahrenheit or more, a new study.

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SCIENMAG: Medicine & Health

AUGUST 14, 2023

Contemporary humans carry in their cells a small amount of DNA derived from Neanderthals and Denisovans. “Denny,” a 90,000-year-old fossil individual, recently identified as the daughter of a Denisovan father and a Neanderthal mother, bears testimony to the possibility that interbreeding was quite common among early human species.

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Testimonials DNA Research 84

Drugs.com

AUGUST 14, 2023

MONDAY, Aug. 14, 2023 -- Some menstrual products -- pads, tampons, cups and underwear -- contain harmful “forever chemicals,” according to new research into the contents of these essential items. Researchers analyzed more than 100 period.

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Production Research 96

SCIENMAG: Medicine & Health

AUGUST 14, 2023

Philadelphia, August 14, 2023 – Bladder cancer has a five-year survival rate of over 80% when detected early, but this rate declines significantly as the disease progresses to advanced stages.

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Disease 84

BioPharma Drive: Drug Pricing

AUGUST 14, 2023

Meet the pharma marketer of the future, primed for personalization and powered by technology.

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Marketing 98

SCIENMAG: Medicine & Health

AUGUST 14, 2023

A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well, in a study led by researchers at Weill Cornell Medicine, the New York Genome Center and the Princess Margaret Cancer Centre in Toronto.

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RNA Disease Research 83