Wed.Jan 15, 2025

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Deep learning designs proteins against deadly snake venom

Science Daily: Pharmacology News

New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.

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FDA Will No Longer Allow Use of Red Dye No. 3 in Food, Drugs

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- The U.S Food and Drug Administration has amended its color additive regulations to no longer allow the use of Federal Food, Drug, and Cosmetic Act (FD&C Act) Red No. 3 in food and ingested drugs.FD&C Red No. 3 is.

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Critical ocean current has not declined in the last 60 years

Science Daily: Pharmacology News

The Atlantic Meridional Overturning Circulation (AMOC) has not slowed down since the mid-20th century based on the North Atlantic air-sea heat fluxes over that time. This finding contrasts with studies that have estimated a decline in the AMOC, likely because previous studies rely on sea surface temperature measurements to understand how the AMOC has changed.

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FDA Proposes New Front-of-Package Food Labels

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Grabbing a quick snack might soon come with a little extra clarity. The U.S. Food and Drug Administration (FDA) has proposed a new rule requiring bold, easy-to-read nutrition labels on the front of food and beverage.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Is eating more red meat bad for your brain?

Science Daily: Pharmacology News

People who eat more red meat, especially processed red meat like bacon, sausage and bologna, are more likely to have a higher risk of cognitive decline and dementia when compared to those who eat very little red meat, according to a new study.

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Bird flu is mutating, but antivirals still work

Science Daily: Pharmacology News

Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.

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Retirement, Mental Health, and Alcohol Use: What They Have in Common

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Retirement is meant to be a persons chance to take it easy and enjoy life.But for many, its a quick route to depression and boozing, researchers reported in a study published Jan. 10 in the journal Aging and Mental Hea.

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This quasar may have helped turn the lights on for the universe

Science Daily: Pharmacology News

Astronomers have detected an intensely brightening and dimming quasar that may help explain how some objects in the early universe grew at a highly accelerated rate. The discovery is the most distant object detected by the NuSTAR X-ray space telescope (which launched in 2012) and stands as one of the most highly 'variable' quasars ever identified.

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Leveraging AI Solutions for Clinical Trial Efficiencies

PPD

As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Ancient genomes reveal an Iron Age society centred on women

Science Daily: Pharmacology News

A groundbreaking study finds evidence that land was inherited through the female line in Iron Age Britain, with husbands moving to live with their wife's community. This is believed to be the first time such a system has been documented in European prehistory.

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Why Google Patents Is Not a Good Solution to Identify Drug Patents

Drug Patent Watch

Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.

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Memory systems in the brain drive food cravings that could influence body weight

Science Daily: Pharmacology News

A research team identified the brain's food-specific memory system and its direct role in overeating and diet-induced obesity. They found a specific population of neurons in the mouse brain that encode memories for sugar and fat, profoundly impacting food intake and body weight.

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Federal watchdog cites concerns with FDA’s accelerated approval process

BioPharma Drive: Drug Pricing

The review, which was spurred by controversy over the FDA's Aduhelm approval, recommends two main changes in agency procedures.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Octopus arms have segmented nervous systems to power extraordinary movements

Science Daily: Pharmacology News

New research has revealed that the nervous system circuitry that controls arm movement in octopuses is segmented, giving these extraordinary creatures precise control across all eight arms and hundreds of suckers to explore their environment, grasp objects, and capture prey.

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At JPM, Biogen CEO tries to take down the deal temperature

BioPharma Drive: Drug Pricing

While Biogen has made an opportunistic bid for partner Sage, its top executive seemed to play down the urgency for his company to go after larger deals.

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Researchers make comfortable materials that generate power when worn

Science Daily: Pharmacology News

Researchers have demonstrated new wearable technologies that both generate electricity from human movement and improve the comfort of the technology for the people wearing them. The work stems from an advanced understanding of materials that increase comfort in textiles and produce electricity when they rub against another surface.

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Drinking Alcohol Is Linked to Health Risks, Says Report

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- A new federal report warns that drinking alcohol could raise your risk of dying early.The draft of the report released Tuesday by the Department of Health and Human Services states that "in the United States, males and.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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This fast and agile robotic insect could someday aid in mechanical pollination

Science Daily: Pharmacology News

New insect-scale microrobots can fly more than 100 times longer than previous versions. The new bots, also significantly faster and more agile, could someday be used to pollinate fruits and vegetables.

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These Incentives Help People, Including Pregnant Smokers, Quit Smoking

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Smokers are better able to quit if theyre offered financial incentives for their efforts.Overall, smokers had up to a 54% better chance at kicking the habit if their quit program offered them cash or vouchers as a r.

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Coyote genes may show urban evolution at work

Science Daily: Pharmacology News

A new study outlines the ways by which city life may be shaping the evolution of urban coyotes, the highly adaptable carnivores spotted in alleyways from Berkeley, Calif., to the Bronx, in New York.

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J&J files a potential blockbuster; Lykos shakes up its board

BioPharma Drive: Drug Pricing

The pharma began submitting its TAR-200 bladder cancer treatment to the FDA. Elsewhere, Sarepta and Madrigal reported strong revenue numbers, while Bausch + Lomb made an acquisition.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Xenon gas could protect against Alzheimer's disease: Mouse study

Science Daily: Pharmacology News

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- approach: using Xenon gas. The study found that Xenon gas inhalation suppressed neuroinflammation, reduced brain atrophy, and increased protective neuronal states in mouse models of Alzheimer's disease.

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Advancing ADC development: Harnessing spatial biology and AI to develop targeted therapeutic strategies

Fierce BioTech

Advancing ADC development: Harnessing spatial biology and AI to develop targeted therapeutic strategies pesurya Wed, 01/15/2025 - 12:41 Wed, 02/26/2025 - 11:00 Resource Type Webinar Trisha Bartlett Atanas Kamburov Promotion Start Wed, 01/22/2025 - 09:00 Promotion End Tue, 07/22/2025 - 09:00 Duration 60 Minutes Today, we stand at an exciting intersection where cutting-edge spatial biology technologies, advanced computational tools, and robust artificial intelligence are converging to transform ou

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Small-scale fisheries essential to global nutrition, livelihoods

Science Daily: Pharmacology News

Small-scale fisheries play a significant but overlooked role in global fisheries production and are key to addressing hunger and malnutrition while supporting livelihoods around the world, according to new research. The study rigorously quantified how marine and inland small-scale fisheries contribute to aquatic harvests and nutritional and socioeconomic security on a global scale.

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Alignment / algorithms

Broad Institute

Alignment / algorithms By lcopelan@broadinstitute.

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Fresh, direct evidence for tiny drops of quark-gluon plasma

Science Daily: Pharmacology News

A new analysis of data from the PHENIX experiment at the Relativistic Heavy Ion Collider (RHIC) reveals fresh evidence that collisions of even very small nuclei with large ones might create tiny specks of a quark-gluon plasma (QGP). Scientists believe such a substance of free quarks and gluons, the building blocks of protons and neutrons, permeated the universe a fraction of a second after the Big Bang.

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