Wed.Jan 15, 2025

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Deep learning designs proteins against deadly snake venom

Science Daily: Pharmacology News

New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.

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FDA Will No Longer Allow Use of Red Dye No. 3 in Food, Drugs

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- The U.S Food and Drug Administration has amended its color additive regulations to no longer allow the use of Federal Food, Drug, and Cosmetic Act (FD&C Act) Red No. 3 in food and ingested drugs.FD&C Red No. 3 is.

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Ancient genomes reveal an Iron Age society centred on women

Science Daily: Pharmacology News

A groundbreaking study finds evidence that land was inherited through the female line in Iron Age Britain, with husbands moving to live with their wife's community. This is believed to be the first time such a system has been documented in European prehistory.

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FDA Proposes New Front-of-Package Food Labels

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Grabbing a quick snack might soon come with a little extra clarity. The U.S. Food and Drug Administration (FDA) has proposed a new rule requiring bold, easy-to-read nutrition labels on the front of food and beverage.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Memory systems in the brain drive food cravings that could influence body weight

Science Daily: Pharmacology News

A research team identified the brain's food-specific memory system and its direct role in overeating and diet-induced obesity. They found a specific population of neurons in the mouse brain that encode memories for sugar and fat, profoundly impacting food intake and body weight.

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People With Lupus Are At Risk for This Type of Heart Disease

Drugs.com

WEDNESDAY, Jan. 15, 2024 -- People with lupus-related skin problems are more likely to develop heart disease associated with hardening of the arteries.Lupus patients with skin symptoms are 72% more likely to develop atherosclerotic heart disease.

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Retirement, Mental Health, and Alcohol Use: What They Have in Common

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Retirement is meant to be a persons chance to take it easy and enjoy life.But for many, its a quick route to depression and boozing, researchers reported in a study published Jan. 10 in the journal Aging and Mental Hea.

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Octopus arms have segmented nervous systems to power extraordinary movements

Science Daily: Pharmacology News

New research has revealed that the nervous system circuitry that controls arm movement in octopuses is segmented, giving these extraordinary creatures precise control across all eight arms and hundreds of suckers to explore their environment, grasp objects, and capture prey.

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Federal watchdog cites concerns with FDA’s accelerated approval process

BioPharma Drive: Drug Pricing

The review, which was spurred by controversy over the FDA's Aduhelm approval, recommends two main changes in agency procedures.

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Small-scale fisheries essential to global nutrition, livelihoods

Science Daily: Pharmacology News

Small-scale fisheries play a significant but overlooked role in global fisheries production and are key to addressing hunger and malnutrition while supporting livelihoods around the world, according to new research. The study rigorously quantified how marine and inland small-scale fisheries contribute to aquatic harvests and nutritional and socioeconomic security on a global scale.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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At JPM, Biogen CEO tries to take down the deal temperature

BioPharma Drive: Drug Pricing

While Biogen has made an opportunistic bid for partner Sage, its top executive seemed to play down the urgency for his company to go after larger deals.

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Researchers make comfortable materials that generate power when worn

Science Daily: Pharmacology News

Researchers have demonstrated new wearable technologies that both generate electricity from human movement and improve the comfort of the technology for the people wearing them. The work stems from an advanced understanding of materials that increase comfort in textiles and produce electricity when they rub against another surface.

Research 110
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Why Google Patents Is Not a Good Solution to Identify Drug Patents

Drug Patent Watch

Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.

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Sensor tech and water filtration: Graphene made permeable for ions

Science Daily: Pharmacology News

A milestone in graphene research: Chemists have succeeded in controlling the passage of halide ions by deliberately introducing defects into a two-layer nanographene system. Their paper shows new perspectives for applications in water filtration or sensor technology.

Research 108
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Drinking Alcohol Is Linked to Health Risks, Says Report

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- A new federal report warns that drinking alcohol could raise your risk of dying early.The draft of the report released Tuesday by the Department of Health and Human Services states that "in the United States, males and.

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Three tiny 'stellar-ghost-town' galaxies discovered

Science Daily: Pharmacology News

By combining data from the DESI Legacy Imaging Surveys and the Gemini South telescope, astronomers have investigated three ultra-faint dwarf galaxies that reside in a region of space isolated from the environmental influence of larger objects. The galaxies, located in the direction of NGC 300, were found to contain only very old stars, supporting the theory that events in the early Universe cut star formation short in the smallest galaxies.

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Leveraging AI Solutions for Clinical Trial Efficiencies

PPD

As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.

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Could this fundamental discovery revolutionize fertilizer use in farming?

Science Daily: Pharmacology News

Researchers have discovered a biological mechanism that makes plant roots more welcoming to beneficial soil microbes.

Research 105
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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These Incentives Help People, Including Pregnant Smokers, Quit Smoking

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Smokers are better able to quit if theyre offered financial incentives for their efforts.Overall, smokers had up to a 54% better chance at kicking the habit if their quit program offered them cash or vouchers as a r.

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Engineers develop breakthrough method for aluminum surfaces, enabling advancements in cooling, self-cleaning and anti-icing technologies

Science Daily: Pharmacology News

An international team of engineers has developed an innovative, scalable method for creating topography-patterned aluminum surfaces, enhancing liquid transport properties critical for applications in electronics cooling, self-cleaning technologies and anti-icing systems.

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J&J files a potential blockbuster; Lykos shakes up its board

BioPharma Drive: Drug Pricing

The pharma began submitting its TAR-200 bladder cancer treatment to the FDA. Elsewhere, Sarepta and Madrigal reported strong revenue numbers, while Bausch + Lomb made an acquisition.

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Songbirds socialize on the wing during migration

Science Daily: Pharmacology News

Evidence from over 18,300 hours of recorded flight calls suggests songbirds may 'talk' to other species as they migrate, forming social connections and -- just maybe -- exchanging information about the journey.

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Alignment / algorithms

Broad Institute

Alignment / algorithms By lcopelan@broadinstitute.

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Critical ocean current has not declined in the last 60 years

Science Daily: Pharmacology News

The Atlantic Meridional Overturning Circulation (AMOC) has not slowed down since the mid-20th century based on the North Atlantic air-sea heat fluxes over that time. This finding contrasts with studies that have estimated a decline in the AMOC, likely because previous studies rely on sea surface temperature measurements to understand how the AMOC has changed.

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LLM for chemistry

Broad Institute

LLM for chemistry By lcopelan@broadinstitute.

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Protein shapes can help untangle life's ancient history

Science Daily: Pharmacology News

The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, according to a new study. It is the first time researchers use data from protein shapes and combine it with data from genomic sequences to improve the reliability of evolutionary trees, a critical resource used by the scientific community for understanding the history of life, monitor the spread of pathogens or create new treatments for disease.

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TBD

Broad Institute

TBD By lcopelan@broadinstitute.

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This quasar may have helped turn the lights on for the universe

Science Daily: Pharmacology News

Astronomers have detected an intensely brightening and dimming quasar that may help explain how some objects in the early universe grew at a highly accelerated rate. The discovery is the most distant object detected by the NuSTAR X-ray space telescope (which launched in 2012) and stands as one of the most highly 'variable' quasars ever identified.

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TBD

Broad Institute

TBD By lcopelan@broadinstitute.

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This fast and agile robotic insect could someday aid in mechanical pollination

Science Daily: Pharmacology News

New insect-scale microrobots can fly more than 100 times longer than previous versions. The new bots, also significantly faster and more agile, could someday be used to pollinate fruits and vegetables.

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Live Far From a Clinic? Telehealth Abortion Services Are on the Rise

Drugs.com

WEDNESDAY, Jan. 15, 2025 -- Women who live far from an abortion clinic depend on telehealth and mail to obtain access to medication abortion, a new study says.Each 100-mile increase in distance from an abortion provider increased telehealth.

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Super-Earth vs. Sub-Neptune? The winner is Super-Venus!

Science Daily: Pharmacology News

New observational data and simulation models have confirmed a new type of planet unlike anything found in the Solar System. This provides another piece of the puzzle to understand how planets and planetary systems form.

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TBD

Broad Institute

TBD By lcopelan@broadinstitute.

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