Tue.Aug 29, 2023

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Pharma maintains high level of trust from UK public and doctors

Drug Discovery World

The pharmaceutical industry continues to maintain strong levels of public trust and favourability in the UK, according to data from the Association of the British Pharmaceutical Industry (ABPI). Opinions showed consistent recognition of the sector’s support for the NHS, with 67% of respondents saying the industry is committed to developing new medicines to meet patient needs.

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Bristol Myers gets key FDA approval for bone marrow disease drug

BioPharma Drive: Drug Pricing

A broadened clearance for Reblozyl in myelodysplastic syndromes should help Bristol Myers offset the looming loss of revenue from top-selling medicines set to soon lose market exclusivity.

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FDA fast-tracks monoclonal antibody for head and neck cancer

Drug Discovery World

Fast Track designation from the Food and Drug Administration (FDA) will accelerate the path to US submission for Alentis Therapeutics’ investigational monoclonal antibody. ALE.C04 is indicated to treat patients with recurrent or metastatic CLDN1-positive head and neck squamous cell carcinoma (HNSCC). Fast Track designation aims to facilitate the development and expedite the review of new medicines that intend to treat serious or life-threatening conditions with unmet medical needs.

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Medicare names first 10 drugs for price negotiations

BioPharma Drive: Drug Pricing

The list includes the top-selling blood thinners Eliquis and Xarelto, as well as the arthritis drug Enbrel and heart failure medicine Entresto.

Drugs 120
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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How do iPSC derived cells support development of gene therapies?

Drug Discovery World

Join DDW for this free event, ‘Discover how iPSC derived cells can be used to support the development of drug and gene therapies’, which is supported by DefiniGEN. The event will take place on 28 September 4PM BST, 5PM CEST, EDT 11AM, PDT 8AM. It will be presented by expert Professor Ludovic Vallier, Chief Scientific Officer, DefiniGEN with an introduction from Dr Chris Kirton Chief Executive Officer of DefiniGEN.

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Doctors Pulled Live Worm From Australian Woman's Brain

Drugs.com

TUESDAY, Aug. 29, 2023 -- Doctors plucked a wriggling roundworm from the brain of an Australian woman in the world's first-known case of human infection with a parasite common in some pythons. The woman, who had been experiencing worsening symptoms.

Doctors 105

More Trending

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Eat Your Veggies:  Writing 'Produce Prescriptions' Could Boost Patients' Health

Drugs.com

TUESDAY, Aug. 29, 2023 -- An apple a day may be just what the doctor ordered. New research on “produce prescription” programs finds that when access to free fruits and vegetables is offered, recipients see measurable benefits in health and.

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DDW Highlights: 29 August 2023

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The headline news this week reflects the high level of interest and investment in neuroscience drug discovery, particularly neurodegenerative diseases like Alzheimer’s; including positive clinical trial results for new immunotherapy and biotherapeutic candidates, and hopes that existing

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Autopsy Study of Athletes Who Died Young Shows Many Had Signs of CTE

Drugs.com

TUESDAY, Aug. 29, 2023 -- The degenerative brain disease known as chronic traumatic encephalopathy (CTE) may be striking some at much younger ages than thought possible: New research has uncovered early signs of the condition in amateur athletes who.

Disease 98
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New DDW Highlights podcast out now

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The headline news this week reflects the high level of interest and investment in neuroscience drug discovery, particularly neurodegenerative diseases like Alzheimer’s; including positive clinical trial results for new immunotherapy and biotherapeutic candidates, and hopes that existing

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Sharing best practice for radiative cooling

SCIENMAG: Medicine & Health

In a world experiencing increased heat stress, a zero-carbon-emission cooling technology that consumes no electricity, operating instead by shedding heat directly into outer space, would be a groundbreaking advance. However, poor standardization and a lack of transparency is hampering this promising technology, known as radiative cooling.

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Golgi Neurosciences Partners with CDD Vault to Drive Innovation in Neurodegenerative Disease Treatment

Collaborative Drug

Milano, Italy and San Francisco, USA, August 29th, 2023 - Golgi Neurosciences S.r.l., a new Italian incubator dedicated to the discovery and development of small molecule-based treatments for neurodegenerative diseases, announced today that it has adopted Collaborative Drug Discovery’s CDD Vault as its platform of choice for managing drug discovery data.

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Wildfire, soil emissions increasing air pollution in remote forests

SCIENMAG: Medicine & Health

Satellite data from across California’s landscapes reveal an increase in nitrogen dioxide levels in remote forest areas, and wildfire and soil emissions are likely the reasons why, according to a paper from University of California, Davis, published today in the journal Environmental Research Letters.

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Rising COVID Hospitalizations, New Variants Have Americans on Edge

Drugs.com

TUESDAY, Aug. 29, 2023 -- A new COVID-19 surge is underway, with seasonal changes and new variants fueling an increase in hospitalizations and deaths. A new Omicron variant, named Eris, has become dominant in the United States amid signs that an.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Scientists continue to push the boundaries of imaging techniques and reveal the mysterious world of molecules

SCIENMAG: Medicine & Health

Scientists from the IOCB Prague, the Institute of Physics of the Czech Academy of Sciences, and Palacký University Olomouc, have once again successfully uncovered the mysteries of the world of molecules and atoms. They have experimentally confirmed the correctness of a decades-old theory that assumed a non-uniform distribution of electron density in aromatic molecules.

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Drug Channels News Roundup, August 2023: Maximizer Problems, Hospital vs. MD Reimbursement, Bureaucracy vs. Costs, And My Favorite Chart Updated

Drug Channels

We’re wrapping up one of newsiest summers in recent memory. Time to pack away your bathing suit, send the kids back to school, and cherish these curated curiosities that I combed from the Jersey Shore: Fresh evidence of patients’ copay maximizer pain How payers pay more to hospitals than to physician offices Surprise? Rationing care via bureaucracy saves money Plus, the June 2023 update to my all-time favorite chart.

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Presenting non-traditional symptoms, women suffer worse heart disease outcomes than men

SCIENMAG: Medicine & Health

Media Contacts: Credit: UMass Lowell Media Contacts: Emily Gowdey-Backus, director of media relations Nancy Cicco, assistant director of media relations More than a dozen medical studies from around the globe show women suffer worse outcomes when diagnosed with and treated for cardiac issues – the No.

Disease 89
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Common origin behind major childhood allergies

Science Daily: Pharmacology News

Several major childhood allergies may all stem from the community of bacteria living in our gut, according to a new study. The research identifies gut microbiome features and early life influences that are associated with children developing any of four common allergies -- eczema, asthma, food allergy and/or hay fever. The findings could lead to methods of predicting whether a child will develop allergies, and ways to prevent them from developing at all.

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Statewide project to provide care and support to people living with dementia and their care partners

SCIENMAG: Medicine & Health

INDIANAPOLIS—An Indiana University School of Medicine statewide project in collaboration with Indiana University Health was recently funded to support people living with dementia as well as their family care partners find more support and resources, thanks to a new $686,000 grant from the National Institute on Aging IMPACT Collaboratory.

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Can an artificial kidney finally free patients from dialysis?

Science Daily: Pharmacology News

Scientists are working on a new approach to treating kidney failure that could one day free people from needing dialysis or having to take harsh drugs to suppress their immune system after a transplant.

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Produce prescription programs yield positive health benefits for participants, study finds

SCIENMAG: Medicine & Health

Around the country, non-profits and local governments are testing the idea of food as medicine through “produce prescription programs”—with promising results, according to researchers from the Friedman School of Nutrition Science and Policy at Tufts University.

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Three-eyed distant relative of insects and crustaceans reveals amazing detail of early animal evolution

Science Daily: Pharmacology News

Scientists use cutting edge scanning technology to reconstruct 'fossil monster' that lived half a billion years ago. The creature's soft anatomy was well-preserved, allowing it to be imaged almost completely: It fills a gap in our understanding of the evolution of arthropods such as insects and crustaceans.

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Molecule reduces inflammation in Alzheimer’s models

SCIENMAG: Medicine & Health

Though drug developers have achieved some progress in treating Alzheimer’s disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked.

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AHA News: The Real-Life Health Effects of Fantasy Sports

Drugs.com

TUESDAY, Aug. 29, 2023 (American Heart Association News) -- Fantasy sports are full of contrasts. They use stats from real athletes to build make-believe teams. They fuel both casual fun with friends and a seriously lucrative industry. And while.

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Want to fight climate change? Don’t poach gorillas (or elephants, hornbills, toucans, etc.)

SCIENMAG: Medicine & Health

Here’s a climate solution we can all get behind: don’t kill elephants. Or poach gorillas – or wipe out tapirs, hornbills, or other large-bodied wildlife that eat fruit and disperse large seeds.

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Quantum discovery offers glimpse into other-worldly realm

Science Daily: Pharmacology News

Experiments promote a curious flipside of decaying monopoles: A reality where particle physics is quite literally turned on its head

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Maintaining stable weight increases longevity among older women

SCIENMAG: Medicine & Health

Reaching the age of 90, 95 or 100, known as exceptional longevity, was more likely for women who maintained their body weight after age 60, according to a multi-institutional study led by University of California San Diego. Older women who sustained a stable weight were 1.

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What Are the Benefits of Generative AI for Pharma?

Fierce BioTech

What Are the Benefits of Generative AI for Pharma? Harnessing generative AI's potential can revolutionize drug discovery and clinical trial recruitment from trial site feasibility and data analysis to patient populations. Our latest perspective explores how using generative AI can accelerate time to market and build modern-day clinical trials. mteefey Tue, 08/29/2023 - 17:01 From trial site feasibility and patient populations to data analysis, generative AI has the potential to revolutionize dru

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Boosting neuroscience training to help children flourish

SCIENMAG: Medicine & Health

Professionals working with children and young people will be offered training in brain science in an Australia-first initiative between The University of Queensland (UQ) and the Australian Research Alliance for Children and Youth (ARACY) through the Thriving Queensland Kids Partnership (TQKP).

Science 81
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Embarking on a Career in Drug Development

Alta Sciences

Embarking on a Career in Drug Development nbartlett Tue, 08/29/2023 - 14:38 Getting to the Heart of Science with Amber malloy Amber Malloy, Altasciences At the heart of science are stories—stories of courage, challenges, successes, lessons, and people. These stories motivate us in the pursuit of knowledge and breathe life into the work we do as Altascientists.

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Sensors harnessing light give hope in rehabilitation

SCIENMAG: Medicine & Health

Recently, a Korean company donated a wearable robot, designed to aid patients with limited mobility during their rehabilitation, to a hospital. These patients wear this robot to receive assistance for muscle and joint exercises while performing actions such as walking or sitting.

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A Comprehensive Guide to Implementing BDD testing in Katalon Studio

Perficient: Drug Development

This article will explore how we can perform BDD testing in Katalon Studio. We will dive into creating a BDD Feature file and Step Definition file in Katalon Studio for a test case and perform execution of the test by two methods: Directly running the Feature file and utilizing in-built Keywords to run it from the Test Case. As we delve deeper, we’ll look into the concept of parameterization in BDD testing by using it in our test case.

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We’re more likely to break conservation rules when we see others doing it too

SCIENMAG: Medicine & Health

Seeing other people break rules can make us act out in ways that we wouldn’t on our own. Applying this psychological concept to fields like conservation could help explain why social influence causes people to make decisions that are harmful to the environment.

Science 80
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Five strategies for enlivening the legacy biopharma campus

Fierce BioTech

Five strategies for enlivening the legacy biopharma campus Once-popular legacy biopharma campuses now represent excess space and costs. It’s time to reimagine and shape their future. Get our five strategies that help breathe new life into your campus and maximize its ROI. jpiatt Tue, 08/29/2023 - 15:22 Discover five creative and innovative ways to reimagine your legacy biopharma campus and unlock value.