Drug Discovery World

AUGUST 23, 2023

New powerful antibiotic Clovibactin seems capable of combating harmful bacteria, and even multi-resistant ‘superbugs’, in a way that makes it more difficult for bacteria to develop resistance against it. Researchers from Utrecht University (Netherlands), Bonn University (Germany), the German Center for Infection Research (DZIF), Northeastern University of Boston (USA), and NovoBiotic Pharmaceuticals (USA) shared the discovery of Clovibactin in the scientific journal Cell.

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Chemical Biology and Drug Design

AUGUST 23, 2023

Trauma-hemorrhagic shock (THS) is a medical emergency and can cause liver injury. Ligustrazine reduces inflammation and apoptosis induced by THS in liver and promotes survival effects. The beneficial effects of ligustrazine against THS-induced hepatic injury, and could be a potential to treat the liver injury caused by THS. Abstract Trauma-hemorrhagic shock (THS) is a medical emergency that is encountered by physicians in the emergency department.

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Drug Discovery World

AUGUST 23, 2023

The US Food and Drug Administration (FDA) has approved the first vaccine for pregnant individuals to prevent respiratory syncytial virus (RSV) in infants. Pfizer’s Abrysvo (Respiratory Syncytial Virus Vaccine) was approved for use at 32-36 weeks gestational age of pregnancy to prevent lower respiratory tract disease (LRTD) and severe LRTD caused by RSV in infants from birth to six months of age.

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BioPharma Drive: Drug Pricing

AUGUST 23, 2023

The company doesn’t know if the needles have caused retinal vasculitis in some people receiving its geographic atrophy drug Syfovre, but is no longer recommending their use.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

AUGUST 23, 2023

Join DDW for this exclusive free event, Are in vitro metabolism and drug-drug interaction studies critical for an investigational new drug application? which is supported by BioIVT. Expert Dr Andrew G Taylor, PhD, ADME Technical Sales Specialist, BioIVT, will present this event which will take place on 5 September 2023, 4PM BST, 11AM EST, 5PM CEST, 8AM PDT.

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Drug Development Drugs 130

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Tainted eye drops are back in the news, with federal regulators warning consumers not to use certain eye drops because of contamination concerns. The U.S. Food and Drug Administration on Tuesday advised people to avoid.

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Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- The number of Americans undergoing gender-affirming surgery is on the rise, new research reveals, almost tripling between 2016 and 2019 alone. During that period, more than 48,000 patients -- about half of them between 19.

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Research 98

BioPharma Drive: Drug Pricing

AUGUST 23, 2023

Data inadvertently published from a closely watched lung cancer study suggest a drug blocking the protein TIGIT may help extend survival, a finding that boosted shares of other developers.

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Drugs 98

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Millions of Americans who experience major depression will suffer a relapse, but a new study suggests that learning to focus on the positive, rather than the negatives in everyday life, might help reduce those.

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BioPharma Drive: Drug Pricing

AUGUST 23, 2023

The funding for Rapport Therapeutics saw participation from a series of so-called crossover investors, many of which have pulled back from biotech startups in recent years.

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Drug Development Drugs 98

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Clinical Trials

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Eye tests are an important way to catch potential eye-related issues in children, but more than two-thirds of kids in the United States are not receiving them at their checkups. Those with Medicaid and other public health.

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Perficient: Drug Development

AUGUST 23, 2023

Today’s environment is relentlessly volatile. It rewards speed over size, agility over efficiency, and cross-functional flow over rigid structure. You must be ready to shift and scale your teams as priorities change. The way forward requires a comprehensive digital strategy that defines the capabilities, agility, and alignment to put you on the right side of digital disruption.

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Marketing 97

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Millions of Americans swear they’re suffering the symptoms of long-haul COVID, but are greeted with eye rolls because they never were formally diagnosed with COVID-19. Their claims need to be taken more seriously.

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SCIENMAG: Medicine & Health

AUGUST 23, 2023

NEW YORK, August 23, 2023 — Physicist Matthew Sfeir is among 21 innovative mid-career scientists who will each receive $1.25 million from the Gordon and Betty Moore Foundation to pursue experimental physics research with the promise of significantly transforming understanding of physics and facilitating next-generation technological breakthroughs.

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Research 93

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Many people with Lou Gehrig’s disease, also called amyotrophic lateral sclerosis (ALS), first start to lose the ability to move their arms and legs. That's not Pat Bennett. She can move just fine. She can still dress.

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Disease 98

SCIENMAG: Medicine & Health

AUGUST 23, 2023

A team of interdisciplinary researchers led by Arindam Banerjee, professor and chair of the Mechanical Engineering and Mechanics Department at Lehigh University, has been awarded nearly $3 million from the National Science Foundation to train a diverse group of future energy-sector leaders across academia, industry, government and policy organizations.

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Engineering Government Science Research 90

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Young people have high levels of distress about climate change, and a new study argues that their anguish could be key to fighting it. “People of all ages are being affected by the climate crisis. Young people in.

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SCIENMAG: Medicine & Health

AUGUST 23, 2023

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse’s lifespan. Credit: University of Rochester photo / J.

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Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- One source of lead exposure in children may surprise you. It’s secondhand smoke, according to a Texas A&M University study. “Further research will likely paint a clearer picture of this exposure route, especially.

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Research 98

SCIENMAG: Medicine & Health

AUGUST 23, 2023

Researchers at UC San Francisco and UC Berkeley have developed a brain-computer interface (BCI) that has enabled a woman with severe paralysis from a brainstem stroke to speak through a digital avatar.   It is the first time that either speech or facial expressions have been synthesized from brain signals.

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Research 89

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- It's long been known that obesity is tied to increased cancer risk, but can weight loss after bariatric surgery help lower a person's odds for the disease? The surgeries have now been around long enough for researchers to.

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Disease Research 98

SCIENMAG: Medicine & Health

AUGUST 23, 2023

When Dr. Bodo Beck first saw the three children of a family who had fled Syria sitting in his consultation room at University Hospital Cologne, the human geneticist was surprised. His genetic analysis diagnosed Bartter syndrome type 3, but never before had he seen such severe joint changes in patients with this rare disease.

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Disease Hospitals 89

BioPharma Drive: Drug Pricing

AUGUST 23, 2023

The job cuts are meant to preserve enough cash so the nearly three-decade-old company can potentially pursue its first drug approval next year.

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Drugs 98

SCIENMAG: Medicine & Health

AUGUST 23, 2023

KANSAS CITY, MO—August 23, 2023—With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons. Now, researchers have revealed one reason why certain anti-cancer compounds can cause unexpected side effects.

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Drugs Drug Development Marketing Research 87

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- When astronauts travel to space, the experience depletes their red blood cells and bone, according to a new study.

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SCIENMAG: Medicine & Health

AUGUST 23, 2023

Fossils of primitive cousins of T. rex that had short, bulldog snouts and even shorter arms have been discovered by scientists in Morocco. The two new dinosaur species belong to the Abelisauridae, a family of carnivorous dinosaurs that were counterparts to the tyrannosaurs of the Northern Hemisphere.

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Science Daily: Pharmacology News

AUGUST 23, 2023

In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan.

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Research 75

SCIENMAG: Medicine & Health

AUGUST 23, 2023

“Stomp, squash, smash” has been the accompanying soundtrack to the expansion of an odd-looking bug through the Eastern US. The spotted lanternfly, a large planthopper native to Asia, has been popularized in media outlets as the most recent enemy one ought to kill on sight.

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Science 87

Drugs.com

AUGUST 23, 2023

WEDNESDAY, Aug. 23, 2023 -- Children need to get up off the sofa and move more, according to a new study that linked childhood sitting time with heart damage in young adulthood. That was true even when the adult's blood pressure and weight were.

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SCIENMAG: Medicine & Health

AUGUST 23, 2023

PLYMOUTH MEETING, PA [August 23, 2023] — Today the National Comprehensive Cancer Network® (NCCN®)—a not-for-profit alliance of leading academic cancer centers—announced Crystal S. Denlinger, MD, FACP, as incoming Chief Executive Officer (CEO). Dr.

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Science Daily: Pharmacology News

AUGUST 23, 2023

A researcher made a discovery that could change our understanding of the universe. He reveals that there is a range in which fundamental constants can vary, allowing for the viscosity needed for life processes to occur within and between living cells. This is an important piece of the puzzle in determining where these constants come from and how they impact life as we know it.

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Research 75

SCIENMAG: Medicine & Health

AUGUST 23, 2023

In the rural United States, an adolescent who drinks heavily has a 43% greater probability of carrying a handgun in the following year, according to a study published this month in The Journal of Rural Health.

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Research 86

Science Daily: Pharmacology News

AUGUST 23, 2023

Researchers used advanced technology to study a massive aggregation of deep-sea octopus gathered at thermal springs near an extinct underwater volcano off the coast of Central California. Warm water from hydrothermal springs accelerates development of octopus embryos, giving young octopus a better chance of survival. The Octopus Garden is the largest known aggregation of octopus on the planet -- the size of this nursery, and the abundance of other marine life that thrives in this rich community,

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Research 75

SCIENMAG: Medicine & Health

AUGUST 23, 2023

With an extendable pole fitted with a small camera, Alison Ke could get a clear view of the inside of a nest box, including one time when a small, green Pacific parrotlet laid eggs. Ke, who earned a Ph.D.

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Research 85