Tue.Apr 23, 2024

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Concussion drug therapies on the horizon

Drug Discovery World

Michael Wyand, PhD, Chief Executive Officer/Director, Oxeia Biopharmaceuticals explains why there’s a need for new drugs to treat traumatic brain injuries. Whereas once it was thought that mild traumatic brain injuries were harmless and symptoms would disappear after a few days of rest, we now know that rest is not enough – these are a major and ongoing public health issue.

Therapies 148
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Researchers create artificial cells that act like living cells

Science Daily: Pharmacology News

Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.

Research 138
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Birmingham Drug Discovery Hub created to turn science into business

Drug Discovery World

The Birmingham Drug Discovery Hub (BDDH) has been set up to help University of Birmingham researchers to overcome the ‘valley of death’, where projects fail due to the funding gap between original research and commercial investment. The hub has attracted more than £4 ($4.9) million in industry funding, grants and industry awards, on the back of just £0.2m investment from the University’s Dynamic Investment Fund (DIF).

Science 130
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Neosporin Ointment in the Nose Might Be Potent Antibiotic

Drugs.com

TUESDAY, April 23, 2024 -- Want to prevent a respiratory infection?A fingerful of Neosporin antibiotic swabbed inside your nose might help you fight off a range of invading respiratory viruses, a new study claims.Lab animals whose noses were.

Virus 116
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Lung organoids provide animal alternative for nanomaterial testing

Drug Discovery World

Lung organoids grown by University of Manchester scientists have been shown to mimic the response of animals when exposed to certain nanomaterials. The study at the University’s NanoCell Biology Lab at the Centre for Nanotechnology in Medicine is published in the journal Nano Today. Though not expected to replace animal models completely, human organoids could soon lead to significant reductions in research animal numbers, the team led by cell biologist and nanotoxicologist Dr Sandra Vranic argu

Research 130
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What is health literacy? Definition and resources

Antidote

Equitable access to medical care is valuable for everyone, and an important part of this equation is health literacy. Health literacy encompasses not just access to medical care, but also the ability to understand and use medical guidance. This can include anything from a doctor’s suggestions, to medication dosage information, and aftercare guidance.

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More Trending

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Innovative Strategies in Drug Repurposing

Drug Patent Watch

Drug repurposing, or identifying new therapeutic uses for existing drugs, is gaining significant momentum as a promising approach to accelerate drug development and reduce costs.

Drugs 111
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Novel multiple myeloma drug recommended for UK NHS use

Drug Discovery World

The UK’s National Institute for Health and Care Excellence (NICE) has published draft guidance recommending the use of Nexpovio (selinexor), in combination with bortezomib and dexamethasone, as a treatment for eligible multiple myeloma patients who have received one or two prior treatments. The recommendation follows recent NICE guidance recommending Nexpovio, in combination with dexamethasone, for eligible myeloma patients who have had four or more prior treatments.

Drugs 130
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Cancer Takes Tough Toll on Family Finances

Drugs.com

TUESDAY, April 23, 2024 -- About six out of 10 working-age adults hit with a cancer diagnosis say it put real pressure on their financial survival, a new report finds.

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Bioluminescence first evolved in animals at least 540 million years ago

Science Daily: Pharmacology News

Bioluminescence first evolved in animals at least 540 million years ago in a group of marine invertebrates called octocorals, according to the results of a new study. The study focuses on an ancient group of marine invertebrates that includes soft corals, pushes back the previous oldest dated example of trait by nearly 300 million years.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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You Might Fare Better If Your Doctor Is Female, Study Finds

Drugs.com

TUESDAY, April 23, 2024 -- The gender of your doctor may play a part in your prognosis: New research shows that hospitalized patients are less likely to die if they’re treated by a female physician.About 10.15% of men and 8.2% of women died while.

Doctors 111
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Squids' birthday influences mating

Science Daily: Pharmacology News

The day a male spear squid hatches determines which mating tactic he will use throughout his life, according to new research. Spear squid (Heterololigo bleekeri) that hatch earlier in the season become 'consorts' which fight for mating opportunities. Those which hatch later become 'sneakers,' which use more clandestine mating tactics. Researchers found that the mating tactic determined by the birth date was fixed for the squid's whole life.

Research 101
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Biden Administration Sets Nursing Home Staffing Minimums

Drugs.com

TUESDAY, April 23, 2024 -- The first-ever minimum staffing rule has been set for nursing homes, the Biden administration announced Monday.Central to the final rule, first proposed in September, is a requirement that a registered nurse be in every.

Nurses 111
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Why Nothing Can Grow on Mars*

Codon

(* = probably.) Two years ago, a friend took me out to coffee in Boston and said, “I think we can engineer an organism to terraform Mars.” Terraforming—transforming a planet so it can support life—has been the perennial dream of science-fiction authors and futurists, who, from Isaac Asimov to Kim Stanley Robinson, envisioned humanity inhabiting a multi-planetary civilization.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Physical Ills Often Plague People With Schizophrenia, Bipolar

Drugs.com

TUESDAY, April 23, 2024 -- Severe mental illness can contribute to a decline in a person’s physical health, with many chronic conditions slowly eroding their wellness, a new review finds.People with schizophrenia or bipolar disorder are more than.

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Fossil frogs share their skincare secrets

Science Daily: Pharmacology News

Palaeontologists have solved a hundred-year-old mystery of how some fossil frogs preserve their fleshy parts -- it's all down to their skin. Palaeontologists studied 45-million-year-old fossil frogs from the Geiseltal site in central Germany. Remarkably, the fossils show full body outlines of the soft tissues. The team discovered that the excellent condition of the fossil frogs is due to preservation of ancient skin remnants.

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Stick to Heimlich Maneuver Not 'Anti-Choking' Devices, FDA Says

Drugs.com

TUESDAY, April 23, 2024 -- People should rely on the well-established Heimlich maneuver to save a choking victim, rather than newfangled “anti-choking” devices, the U.S. Food and Drug Administration says.“The safety and effectiveness of.

FDA 105
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Neurocrine scores surprise win with depression drug

BioPharma Drive: Drug Pricing

Shares of the biotech rose about 5% after a medicine licensed from Takeda hit the main and key secondary goals of a mid-stage study focused on major depressive disorder.

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Repeat Blasts Can Damage Soldiers' Brains, Study Confirms

Drugs.com

TUESDAY, April 23, 2024 -- Soldiers can suffer brain injury if they are repeatedly exposed to explosive blasts, a new study shows.Further, the more frequently a soldier is exposed to explosions, the greater their risk for brain injury, researchers.

Research 105
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FDA rejects Abeona cell therapy, asks for more manufacturing data

BioPharma Drive: Drug Pricing

The complete response letter for Abeona’s treatment is one of several manufacturing setbacks for cell and gene therapy developers in recent years.

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CDC Launches Online 'Heat Forecaster' Tool as Another Summer Looms

Drugs.com

TUESDAY, April 23, 2024 -- Last summer was a record-breaker for heat emergencies, so the U.S. Centers for Disease Control and Prevention on Monday launched a new online heat forecaster to help folks better prepare as summer nears.The HeatRisk.

Disease 104
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Former Bristol Myers CEO tapped as Novartis’ next board chair

BioPharma Drive: Drug Pricing

Giovanni Caforio, who left Bristol Myers in November after eight years as CEO, is set to succeed Novartis’ longtime board chair Joerg Reinhardt next year.

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Women in the Military at Risk for Low-Weight Babies

Drugs.com

TUESDAY, April 23, 2024 -- Active military service appears to increase a woman’s risk of having a low birthweight baby, a new review finds.Nearly two-thirds of studies (63%) conclude that women on active service could be at higher risk of having.

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Novartis raises forecasts as top drug sales beat Wall Street estimates

BioPharma Drive: Drug Pricing

Sales of Entresto and Cosentyx grew faster in the first quarter than analysts anticipated, helping drive the quarterly beat and raise.

Drugs 70
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Taking Psilocybin for Depression? Relationship With Therapist Is Key

Drugs.com

TUESDAY, April 23, 2024 -- Many people dogged by depression are turning to the psilocybin found in "magic mushrooms" to ease the condition, and often reporting success.Now, new research suggests much of the credit for that success lies in the.

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New patent for Neos Theraps drug ADZENYS XR-ODT

Drug Patent Watch

Annual Drug Patent Expirations for ADZENYS+XR-ODT Adzenys Xr-odt is a drug marketed by Neos Theraps and is included in one NDA. It is available from one supplier.

Drugs 59
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Customer Experience Revolution: Perficient’s Twilio Partnership

Perficient: Drug Development

Thinking that we are a company that is in constant growth with talent located around the world, we must seek strategies that allow us to expand all the knowledge we have globally to be able to meet the challenges of the market regardless of our location and thus provide the best customer experience, deliver the greatest possible value to our customers, and increase growth opportunities for the people who are part of Perficient.

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Crucial Data Solutions Introduces TrialKit PACS to Streamline Image Management in Clinical Trials

Crucial Data Solutions

RENO, Nev.–(BUSINESS WIRE)–Crucial Data Solutions (CDS), a leading provider of data collection and trial management software to advance clinical research, The post Crucial Data Solutions Introduces TrialKit PACS to Streamline Image Management in Clinical Trials appeared first on Crucial Data Solutions.

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New tentative approval for Xiamen Lp drug topiramate

Drug Patent Watch

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Drugs 59
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Overcoming the complexity of free energy perturbation calculations

Drug Target Review

Drug discovery is a complex process, where millions of compounds are investigated throughout the initial hit identification, hit-to-lead, and lead optimisation stages. 1 Throughout the discovery process, compounds are synthesised, screened, and eliminated based on their developability. The process of drug discovery is lengthy, and it can take 2-5 years on average to reach the preclinical phase. 1 To overcome the bottleneck of synthesising compounds of interest and forming derivatives for lead op

Licensing 100
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Which pharmaceutical companies have the most lotion dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most lotion dosed drugs. For a different perspective, see the most popular dosage types.

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Interim Staffing: Reinvigorating Your Human Research Protections Program

Advarra

Evolving regulations, technological advancements, changing societal norms, and new research methodologies can cause an organization to pause and think, “Does our human research protection program (HRPP) have the proper expertise, policies, and procedures in place? Are we ready for increasing new single IRB (sIRB) mandates? Should we pursue accreditation?