Drug Discovery World
AUGUST 22, 2023
Bloom Science has announced positive topline data from a Phase I clinical trial of BL-001 , a potential first-in-class therapeutic the company is developing for Dravet syndrome and amyotrophic lateral sclerosis (ALS). In the trial, BL-001 demonstrated a favourable safety profile and was well tolerated with no serious adverse events (SAEs) across all four dose cohorts.
BioPharma Drive: Drug Pricing
AUGUST 22, 2023
Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.
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Drug Discovery World
AUGUST 22, 2023
AstraZeneca’s Forxiga (dapagliflozin) has been approved in China to reduce the risk of cardiovascular death, hospitalisation for heart failure (HF), or urgent HF visits in adults with symptomatic chronic HF. The drug was previously approved in China but was limited to HF patients with reduced ejection fraction (HFrEF). The approval by China’s National Medical Products Administration (NMPA) is based on positive results from the DELIVER Phase III trial.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- British researchers may have found a way to diagnose Parkinson’s disease several years sooner. Researchers at University College London and Moorfields Eye Hospital say that eye scans may be able to detect signs of.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
AUGUST 22, 2023
Claire D’Abreau-Hayling, Chief Scientific Officer at Sandoz, examines how generic products can relieve industry pressure and improve access to essential medicines. Off-patent medicines today account for about 80% of global prescriptions at an estimated 20% of the total cost. This will continue to be the case going forward, but the nature of the off-patent landscape will evolve in line with ongoing changes in the segment’s ‘pipeline’: the originator products of today, which will become the gen
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- Too much screen time can lead to developmental delays in babies, researchers say. When 1-year-olds viewed screens for more than four hours a day, they had delays in communication and problem-solving skills when assessed at.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- A strain of listeria bacteria found in milkshakes at a restaurant in Washington state has been linked to six hospitalizations and three deaths. The milkshakes were sold at Frugals restaurant in Tacoma, Wash. Only the.
Perficient: Drug Development
AUGUST 22, 2023
Aria labels provide alternate text to adaptive technology tools such as screen readers. This helps website visitors navigate the site more accurately. One use case for aria-labels is on html anchor tags. Sitecore does not a way to manage this text by default. Follow along and I’ll show you how to modify the various link dialogs and give content authors the ability to manage this text.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- Misinformation about health and medicine is rampant in the United States, with far too many Americans being presented false claims and left wondering what to believe, a new survey reports. At least 4 in 10 people say.
Perficient: Drug Development
AUGUST 22, 2023
To meet clinical, business, and evolving consumer needs, healthcare and life sciences organizations are focused on care delivery that enables innovation in patient engagement, data and analytics, and virtual care. According to Gartner’s 2022 Industry Cloud Survey , about 40% of IT leaders say they have started to adopt industry cloud platforms, with another 15% in pilots; another 15% are considering deployment by 2026.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- From receiving no response to cries for help to being verbally abused, 1 in 5 U.S. mothers say they were mistreated by a health care professional during pregnancy and delivery. Rates of mistreatment during maternity care.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
PROVIDENCE, R.I. [Brown University] — One of the most common and practically useful experiments in all of fluid dynamics involves holding an object in air or submerging it fully underwater, exposing it to a steady flow to measure its resistance in the form of drag.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- The degenerative joint disease osteoarthritis affects 15% of the global population over age 30, so by 2050 that could be nearly 1 billion people, researchers say. Living longer and obesity are both major.
BioPharma Drive: Drug Pricing
AUGUST 22, 2023
The pharma’s suit, which claims Medicare’s new power to negotiate certain drug prices is unconstitutional, comes days before the agency will reveal the first 10 medicines to be included under the plan.
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Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- People can help reduce their odds of developing atrial fibrillation or stroke through one piece of standard medical advice: stay fit. According to a new study in 15,000 people, physical fitness was found to have a lower.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
Amsterdam, Netherlands – 23 Aug 2023: Hours of inactivity during childhood could be setting the stage for heart attacks and strokes later in life, according to research presented at ESC Congress 2023.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- If you’ve had a heart attack, your doctor likely told you to take a low-dose aspirin daily to stave off a second heart attack or stroke, but most people don’t follow through with this advice over the.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
ROCKVILLE, Md.—For the first time, researchers have discovered that the ventral tegmental area (VTA) of the brain—a key structure involved in motivation and reward appreciation has altered connectivity patterns with specific brain regions in patients with obesity.
BioPharma Drive: Drug Pricing
AUGUST 22, 2023
The biotech, which aims to develop an alternative to existing medicines and emerging gene-based treatments, will focus further testing on sicker patients.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
It’s human nature to be judgmental. But why do we place less blame on someone, or give more praise, if we find out that person had a history of suffering in childhood? In a recent study, University of Missouri researchers discovered why someone’s childhood adversity influences how others judge their behavior.
addgene Blog
AUGUST 22, 2023
If you’re interested in learning a new skill, getting access to equipment you don’t have, or maybe both, a visiting scientist stint may be ideal for you. Here, we will chat about who might want to explore this role, how to seek out such an arrangement, and how to operate once in that position.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
When UCLA shifted to remote instruction during the early days of COVID-19, the campus was much less populated — but it wasn’t totally empty. Several species of animals continued to go about their daily lives, just with far fewer disturbances from humans.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- Women may soon have a vaccine they can take during a pregnancy to help protect their newborn from respiratory syncytial virus (RSV), following U.S. Food and Drug Administration approval of the shot, called Abrysvo, on.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
Australia’s iconic grass-trees – aka yaccas – are hardy, drought-tolerant, and strikingly beautiful. Now, new research has revealed another, far more important, feature: their ability to protect wildlife from deadly weather extremes. Credit: University of South Australia Australia’s iconic grass-trees – aka yaccas – are hardy, drought-tolerant, and strikingly beautiful.
Drug Channels
AUGUST 22, 2023
Last week, Anna Matthews of The Wall Street Journal scored a market-moving scoop with her story about Blue Cross of California’s decision to ditch CVS Health’s Caremark pharmacy benefit manager (PBM) in favor of five separate vendors. ICYMI: A Big Health Insurer Is Ripping Up the Playbook on Drug Pricing I commend Blue Shield of California for undertaking a noble experiment to unbundle the PBM business model.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
Silicon is one of the most pervasive functional materials of the modern age, underpinning semiconductor technologies ranging from microelectronics to solar cells. Indeed, silicon transistors enable computing applications from cell phones to supercomputers, while silicon photovoltaics are the most widely deployed solar-cell technology to date. The U.S.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- Women may soon have a vaccine they can take during a pregnancy to help protect their newborn from respiratory syncytial virus (RSV), following U.S. Food and Drug Administration approval of the shot, called Abrysvo, on.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
Structural formulae show how chemical compounds are constructed, i.e., which atoms they consist of, how these are arranged spatially and how they are connected.
Drugs.com
AUGUST 22, 2023
TUESDAY, Aug. 22, 2023 -- When it comes to the array of different microorganisms found in the human gut, more is better: A more diverse microbiome is a healthier microbiome. Now, initial results of a small, ongoing study suggests that weight loss.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
COLUMBUS, Ohio – Train elementary school students how to be creative and you can help increase their resilience in the face of real-life problems, new research suggests.
Science Daily: Pharmacology News
AUGUST 22, 2023
Researchers are pursuing various solutions for administering insulin to those with Diabetes. One such solution is to enclose insulin-producing designer cells in capsules that can be implanted in the body and triggered externally. Researchers have discovered a novel stimulation method using music to trigger cells to release insulin. Their solution works especially well with 'We Will Rock You' from the British rock band, Queen.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
One of the most feared effects of global warming is the rise in sea level caused by the melting of polar continental ice. In fact, polar researchers have been working towards raising the awareness of this impending threat.
Eye on FDA
AUGUST 22, 2023
For the second time this month and the third time this year, FDA’s OPDP has posted notice that it has taken an enforcement action. Last week, a Warning Letter was posted regarding a sales aid. This week it action came in the form of an Untitled Letter (NOV) sent to a company regarding a paid social media posting. Enforcement this year was non-existent until June when the agency posted its first letter in a year.
SCIENMAG: Medicine & Health
AUGUST 22, 2023
Breast, colorectal and lung cancers are significant public health burdens in the U.S., accounting for more than 688,000 newly-diagnosed cancers in 2023, with significant racial and ethnic disparities in disease incidence and mortality, according to the American Cancer Society.
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