Drug Discovery World

SEPTEMBER 12, 2023

Twist Bioscience and Ono Pharmaceutical will combine their efforts to discover and develop novel antibodies for the treatment of autoimmune diseases. Under the terms of the agreement, Twist will use its ‘Library of Libraries’ to conduct research activities to discover novel antibodies against targets identified by Ono. Twist also recently entered a research collaboration with Cancer Research Horizons.

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addgene Blog

SEPTEMBER 12, 2023

Primer design. Plasmid mapping. DNA sequence analysis. We all have our favorite tools for tackling these particular tasks, but they tend to be scattered about the internet. To help you keep your virtual molecular biology toolbox organized, today’s post features a list of free online molecular biology tools all in one place.

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Drug Discovery World

SEPTEMBER 12, 2023

Hosted by DDW and co-sponsored by Benchling and Proscia, “AI and Lab Automation: What are the key benefits and latest innovations?” will be free to attend on 10 October at 7AM PDT / 10AM EST / 3PM BST / 4PM CET. Join this free webinar to learn about the key benefits and latest innovations to be aware of in AI and lab automation. Maria Gil will discuss how the future of healthcare is data-driven and is being bolstered by analytics and powered by AI and automation.

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Drug Discovery Today

SEPTEMBER 12, 2023

Sandwich, UK, 7th September 2023 / Sciad Newswire / Discovery Park, Kent’s thriving life science community, welcomes today’s announcement that the UK will re-join the EU’s Horizon science research programme.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Chemical Biology and Drug Design

SEPTEMBER 12, 2023

Based on molecular docking, two series of novel dual inhibitors of XOR and URAT1 containing benzoic acid were designed. Among them, B 5 had the best inhibitory activity with similar inhibitory effects on XOR and URAT1, with IC 50 values of 12.0 ± 1.0 nM and 30.24 ± 3.46 μM, respectively, could be put into further study for more details. Abstract Xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1) are involved in the production and reabsorption of uric acid, respectively.

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BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Arialys Therapeutics launched Tuesday with $58 million in funding from a group of life sciences investors that includes Johnson & Johnson’s venture arm.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Following on an approval granted Monday by the U.S. Food and Drug Administration, an expert panel from the Centers for Disease Control and Prevention late Tuesday also signed off on new COVID boosters for Americans. Final.

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Disease Drugs 116

Drug Patent Watch

SEPTEMBER 12, 2023

In the world of patents, the right to exclude others from using or selling an invention is granted only during the patent’s validity. Once a patent expires, this exclusivity vanishes.… The post Understanding Patent Term Extensions: An Overview appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Staying up late comes naturally to some folks, whether they’re working or relaxing deep into the night. But being a night owl might come at a cost to one’s health. People who are night owls have a higher risk than.

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Drug Patent Watch

SEPTEMBER 12, 2023

In a recent STAT article Sanofi CEO Paul Hudson discusses the potential of artificial intelligence (AI) in the pharmaceutical industry. While some in the industry have been hesitant to embrace… The post From Expert AI to Snackable AI: A New Era in Pharma, as Seen by Sanofi’s CEO appeared first on DrugPatentWatch - Make Better Decisions.

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Pharmaceuticals 109

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Many Americans are behind on recommended colon cancer screenings -- and their doctors often fail to remind them, a new study suggests. The study, by the American Cancer Society, focused on a nationwide sample of more.

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Doctors 110

On Medicine

SEPTEMBER 12, 2023

Why is this research necessary? The Russian invasion of Ukraine started in February 2022 and is the largest European ground offensive since World War II. Countless civilians have been killed, and millions of children, women, and elderly people have fled the country. One study found that adolescents living in war-torn regions of Ukraine were at increased risk of experiencing depression, anxiety, and post-traumatic stress symptoms than those in the peaceful areas.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Certain combinations of bacteria found in dust in children’s day care settings may have an impact on their young lungs. Researchers are trying to understand whether attending day care can affect children’s lung health.

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Research 105

BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Citing “near-term headwinds,” the cancer cell therapy developer will lay off 176 employees and pare back some of its research spending.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Bolstering the notion that a strong body equals a strong mind, new research indicates that the more inactive seniors are, the higher their risk for dementia. The finding stems from a look at the onset of dementia among.

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Research 105

BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

The two-year-old San Diego biotech is allied with The Jackson Laboratory to engineer better mouse models of the rare diseases it plans to target.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- The singer Paul Simon is coping with hearing loss in his left ear, something he told an audience Sunday he’s starting to accept. “I haven’t accepted it entirely, but I’m beginning to,” Simon told an audience at.

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Collaborative Drug

SEPTEMBER 12, 2023

Hyderabad and San Francisco, September 12, 2023 - LAXAI Life Sciences, a leading Contract Research, Development, and Manufacturing Organization (CRDMO), has announced the adoption of the CDD Vault informatics platform. This strategic move underscores LAXAI’s commitment to combining science and innovation, reinforcing its clients’ competitive advantage through high-quality, efficient services.

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Science Research 94

Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Young people who vape are more likely to experience chronic stress, though it isn’t clear whether it was the stress that brought on the vaping or the vaping that caused the stress, investigators say. “Research is.

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Research 105

Science Daily: Pharmacology News

SEPTEMBER 12, 2023

At the center of every galaxy is a supermassive black hole. Beyond a certain size, these become active, emitting huge amounts of radiation, and are then called quasars. It is thought these are activated by the presence of massive dark matter halos (DMH) surrounding the galaxy, directing matter towards the center, feeding the black hole. A team has now surveyed hundreds of ancient quasars and found this behavior is very consistent throughout history.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- For decades, sick people have been taking essentially worthless over-the-counter cold remedies to clear their stuffy noses, a key advisory panel for the U.S. Food and Drug Administration said Tuesday. The panel voted.

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BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Johnson & Johnson and Bristol Myers Squibb have joined a group of new investors backing Rosana Kapeller’s startup, which launched in 2020 after incubating with GV.

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Drugs 73

Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- Seniors, pick up those knitting needles, some paintbrushes or that favorite novel, because new research suggests that having a hobby is linked to having lower depression in older people. Hobbies might include anything from.

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Research 81

Chemical Biology and Drug Design

SEPTEMBER 12, 2023

Cover Image © molekuul_be/Shutterstock.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- So much for the powerful feminist messaging in the new Barbie movie. Director Greta Gerwig’s feminist interpretation of Barbie depicted the fashion dolls as judges, surgeons, naval officers, astronauts and U.S.

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BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Acelyrin’s share value collapsed Tuesday after its lead drug fell short in the company’s first big trial test since it raised $540 million in a May IPO.

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Trials Drugs 67

Fierce BioTech

SEPTEMBER 12, 2023

According to FDA 820.3(z), “Validation means confirmation by examination and provision of objective evidence that the particular requirements for a specific intended use can be consistently ful | How do we deliver objective evidence with a high degree of certainty that it will withstand regulatory scrutiny? Digital validation tools hold the answer.

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FDA 59

BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2023

Fitch Ratings called the deal to buy the Xiidra treatment “strategically sound” even as the company’s plan for funding the deal would increase its leverage.

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Drug Patent Watch

SEPTEMBER 12, 2023

Annual Drug Patent Expirations for SODIUM+THIOSULFATE Sodium Thiosulfate is a drug marketed by Us Army and Hope Pharms and is included in two NDAs. It is available from one supplier.… The post New patent for Hope Pharms drug SODIUM THIOSULFATE appeared first on DrugPatentWatch - Make Better Decisions.

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H1 Blog

SEPTEMBER 12, 2023

At every industry conference this fall, half of the sessions will likely be focused on artificial intelligence (AI) and how important it is. The challenge is in knowing how AI will actually be impactful. Having seen the challenges that come with adopting a paradigm shifting technology, I think it is important to share some perspective on how AI can be thought of in more traditional terms to help bridge the gap for immediate use.

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Production 59

Drug Patent Watch

SEPTEMBER 12, 2023

Annual Drug Patent Expirations for NITHIODOTE Nithiodote is a drug marketed by Hope Pharms and is included in one NDA. It is available from one supplier. There are six patents… The post New patent for Hope Pharms drug NITHIODOTE appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

SEPTEMBER 12, 2023

TUESDAY, Sept. 12, 2023 -- It’s possible that the cause of spontaneous, recurring brain hemorrhages can be passed through blood transfusion, researchers say. The likelihood of this happening is very slim, however. Still, “blood transfusions are.

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Research 59

ACTO

SEPTEMBER 12, 2023

Gamification is playing a vital role in transforming learning within pharmaceutical sales training. The Learning Journey podcast recently conducted an in-depth exploration of the impact of gamification on commercial learning in the Life Sciences industry. Expert David Noonan, Senior Director of Business Development at Red Nucleus, leads the conversation and demystifies how gamification transforms training, addresses adult learners' needs, and reshapes how Commercial Learning and Development (CL&

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Perficient: Drug Development

SEPTEMBER 12, 2023

This illuminating article will delve deep into the intricacies of seamlessly extracting and channeling JSON values between API requests, i.e., request-response Chaining. From creating and parameterizing REST API requests to scripting a symphony of response interactions, we will illuminate every facet of the process. Brace yourself to witness the synergy of theory and practice as we unveil the outcome through meticulous execution.

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