Drug Target Review
JANUARY 8, 2024
What is “healthspan” and how does it relate to Life Bioscience’s mission? It is no mystery that as we age our health starts to deteriorate, and we become increasingly susceptible to diseases. If we take into consideration the timeframe of our lives, our “healthspan” is defined as the number of healthy years we live, which is different than our lifespan, the number of years of life.
Broad Institute
JANUARY 8, 2024
Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice By Corie Lok January 8, 2024 Breadcrumb Home Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice By adapting virus-like particles to carry the machinery for a type of gene editing called prime editing, scientists have corrected disease-causing mutations in animals and increased editing efficiency.
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Practical Cheminformatics
JANUARY 8, 2024
Picking up where we left off in Part I , this post covers several other ML in drug discovery topics that interested me in 2023. Some areas, like large language models, are new, and most of the work is at the proof-of-concept stage. Others, like active learning, are more mature, and several groups are starting to explore nuances of the methods. Here’s the structure of Part II. 4.
Science Daily: Pharmacology News
JANUARY 8, 2024
In recent years, there has been rising concern that tiny particles known as microplastics are showing up basically everywhere on Earth, from polar ice to soil, drinking water and food. Formed when plastics break down into progressively smaller bits, these particles are being consumed by humans and other creatures, with unknown potential health and ecosystem effects.
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The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
ASPET
JANUARY 8, 2024
This Commentary delves into the current progress and challenges on ongoing research on medical countermeasures (MC) for chemical, biological, radiological, and nuclear (CBRN) threats. CBRN agents pose a serious risk to human health and safety, with the potential for mass casualties in both military and civilian settings. Chemical threats are toxic compounds that could be used in a terrorist attack, an accidental release, or chemical warfare.
Science Daily: Pharmacology News
JANUARY 8, 2024
Researchers have developed a new lithium metal battery that can be charged and discharged at least 6,000 times -- more than any other pouch battery cell -- and can be recharged in a matter of minutes. The research not only describes a new way to make solid state batteries with a lithium metal anode but also offers new understanding into the materials used for these potentially revolutionary batteries.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
JANUARY 8, 2024
In this eBook, we explore how researchers identified two unique proteins within N. fowleri – self-activating guanine nucleotide-hydrolysing proteins (G proteins) – that present novel targets for drug discovery. This article summarises their work to date, including a high-throughput fluorescence assay of guanine nucleotide hydrolysis for rapid But that’s not all.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- Folks quenching their thirst with bottled water can expect to chug down hundreds of thousands of minute plastic particles with their refreshing H2O, a new study reports.On average, a liter of bottled water contains some.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
At the J.P. Morgan Healthcare Conference Monday, company head Chris Viehbacher said insurance reimbursement is now ‘not an issue’ for treatment.
Science Daily: Pharmacology News
JANUARY 8, 2024
A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- Paxlovid might help shorten and diminish a COVID infection, but the antiviral doesn’t reduce the risk of developing long COVID, a new study shows.About 16% of COVID patients treated with Paxlovid wound up with long COVID.
Science Daily: Pharmacology News
JANUARY 8, 2024
In the culmination of a decade's worth of effort, scientists analyzed an unprecedented sample of more than 1,500 supernovae classified using machine learning. They placed the strongest constraints on the expansion of the universe ever obtained with the DES supernova survey. While consistent with the current standard cosmological model, the results do not rule out a more complex theory that the density of dark energy in the universe could have varied over time.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- Applesauce fruit puree pouches under recall and investigation for toxic lead levels may also contain another toxin, chromium, according to an update released Friday by the U.S. Food and Drug Administration (FDA).The products.
Science Daily: Pharmacology News
JANUARY 8, 2024
An international team of researchers has found that Africa's birds of prey are facing an extinction crisis. The report warns of declines among nearly 90% of 42 species examined, and suggests that more than two-thirds may qualify as globally threatened.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- Exposing babies and toddlers to TV and other digital media could be linked to a heightened risk for dysfunction in what's known as "sensory processing," a new study warns. Kids with "atypical sensory processing" are often.
On Medicine
JANUARY 8, 2024
Kidney cancer poses a significant healthcare burden in the UK, with 13,000 new patients diagnosed annually, a 52% survival rate, and nearly 5,000 patients dying each year. The US faces similar problems, with 81,000 new cases and nearly 14,000 deaths annually. The incidence of renal cell carcinoma (RCC) has more than doubled in the last 50 years and is increasing by 2-3% every year.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- With donations falling to the lowest levels in 20 years, the American Red Cross declared a national blood shortage on Sunday. “One of the most distressing situations for a doctor is to have a hospital full of.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
The acquisition will build out Merck’s pipeline of immunotherapies as its top-seller Keytruda nears the end of U.S. market exclusivity.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
JANUARY 8, 2024
The article “Settled: Patent characteristics and litigation outcomes in the pharmaceutical industry,” explores the relationship between Paragraph IV litigation characteristics and the probability of a Paragraph IV settlement in the… The post Unveiling the Secrets of Patent Litigation and Settlements in Pharmaceuticals appeared first on DrugPatentWatch - Make Better Decisions.
Science Daily: Pharmacology News
JANUARY 8, 2024
Babies and toddlers exposed to television or video viewing may be more likely to exhibit atypical sensory behaviors, such as being disengaged and disinterested in activities, seeking more intense stimulation in an environment, or being overwhelmed by sensations like loud sounds or bright lights, according to recent data.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
An unusual FTC challenge could have implications for startups, while industry watchers are waiting to see if the sector’s recent momentum signals an end to a lengthy funding crunch.
Science Daily: Pharmacology News
JANUARY 8, 2024
Researchers have developed a new soft robot design that engages in three simultaneous behaviors: rolling forward, spinning like a record, and following a path that orbits around a central point. The device, which operates without human or computer control, holds promise for developing soft robotic devices that can be used to navigate and map unknown environments.
SCIENMAG: Medicine & Health
JANUARY 8, 2024
LA JOLLA, CA— Ethanol—the compound found in alcoholic beverages—interferes with the normal functioning of a long list of biological molecules, but how each of these interactions contributes to the behavioral effects of alcohol is not fully understood.
addgene Blog
JANUARY 8, 2024
Today marks Addgene's 20th anniversary! We've done so much in the past two (2!) decades that it's hard to summarize, but we wanted to mark the occasion by trying.
SCIENMAG: Medicine & Health
JANUARY 8, 2024
FORT COLLINS, Colo., Jan. 8, 2024 — What’s all the buzz about? Most garden enthusiasts know that certain flowers can attract pollinators. New research helps explain why, and also provides more details about how the nutrition found in plant pollen may determine which specific bee communities might favor your garden.
Nvidia Developer: Drug Discovery
JANUARY 8, 2024
The search for viable drugs is one of the most formidable challenges at the intersection of science, technology, and medicine. Mathematically, the odds of. The search for viable drugs is one of the most formidable challenges at the intersection of science, technology, and medicine. Mathematically, the odds of randomly stumbling across a good therapeutic candidate are staggeringly small.
Science Daily: Pharmacology News
JANUARY 8, 2024
A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- 'Freezing' is a common and debilitating symptom of Parkinson’s disease, with patients suddenly finding themselves unable to move their feet forward.Drugs, surgeries and behavioral therapies have all proven rather.
Science Daily: Pharmacology News
JANUARY 8, 2024
Astronomers have detected a three-ringed structure in the nursery of planets in the inner planet-forming disk of a young star. This configuration suggests two Jupiter-mass planets are forming in the gaps between the rings. The detailed analysis is consistent with abundant solid iron grains complementing the dust composition. As a result, the disk likely harbors metals and minerals akin to those in the Solar System's terrestrial planets.
SCIENMAG: Medicine & Health
JANUARY 8, 2024
Every year, about 800,000 new stroke cases are reported in the United States, often causing patients problems with both neurological and physical motor control. Disruptions in the mobility of the arms and hands, in particular, can have devastating impacts on stroke patients’ quality of life.
Science Daily: Pharmacology News
JANUARY 8, 2024
Africa has a huge diversity of large mammals, but their evolutionary relationships and movement across the continent over time often remain a mystery. A new scientific study sheds light on longstanding questions about the interplay between evolution and geography in one of these mammals, namely the iconic African bushpig, and helps settle a major question regarding prehistoric human activities shaping biodiversity patterns in Africa.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
Small and mid-sized drugmakers shed at least 10,000 jobs in 2023, according to data compiled by BioPharma Dive, but recent deal, stock market momentum have brought some optimism.
Science Daily: Pharmacology News
JANUARY 8, 2024
Astronomers believe they may have found the origin of the universe's giant odd radio circles: they are shells formed by outflowing galactic winds, possibly from massive exploding stars known as supernovae.
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