Thu.Mar 28, 2024

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New imaging method illuminates oxygen's journey in the brain

Science Daily: Pharmacology News

A new bioluminescence imaging technique has created highly detailed, and visually striking, images of the movement of oxygen in the brains of mice. The method, which can be easily replicated by other labs, will enable researchers to more precisely study forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack.

Disease 352
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U.S. Mpox Cases Rising Again as Vaccinations Lag

Drugs.com

THURSDAY, March 28, 2024 -- Mpox cases are climbing again in the United States, with the number of reported infections now twice as high as they were at this time last year, new government data shows.In response, public health experts have raised.

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Alcohol raises heart disease risk, particularly among women

Science Daily: Pharmacology News

Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session. The risk was highest among both men and women who reported heavy episodic drinking, or 'binge' drinking, and the link between alcohol and heart disease appears to be especially str

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Cases of Drug-Resistant Gonorrhea Have Tripled in China, Posing a Global Threat

Drugs.com

THURSDAY, March 28, 2024 -- A strain of highly antibiotic-resistant gonorrhea first emerged in China in 2016, and cases of this tough-to-treat infection have tripled there in just five years, Chinese researchers report. It's a warning to the rest.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Mechanism found to determine which memories last

Science Daily: Pharmacology News

Neuroscientists have established in recent decades the idea that some of each day's experiences are converted by the brain into permanent memories during sleep the same night. Now, a new study proposes a mechanism that determines which memories are tagged as important enough to linger in the brain until sleep makes them permanent.

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DNA study IDs descendants of George Washington from unmarked remains, findings to aid service member IDs going back to World War II

Science Daily: Pharmacology News

New DNA sequencing technologies have identified the historical remains of George Washington's grandnephews, Samuel Walter Washington and George Steptoe Washington Jr., and their mother, Lucy Payne Washington, from unmarked, fragmentary bones left at the Harewood family cemetery in Charles Town, West Virginia, in the mid-1800s.

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FDA approves Akebia anemia pill, two years after rejection

BioPharma Drive: Drug Pricing

The agency gave Akebia’s drug an OK after receiving more safety data, but imposed a strict boxed warning for its use that may limit uptake.

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Cell division quality control 'stopwatch' uncovered

Science Daily: Pharmacology News

Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.

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Hormonal Meds for Birth Control, Menopause Linked to Brain Tumors

Drugs.com

THURSDAY, March 28, 2024 -- The contraceptive injection Depo-Provera and two drugs used for menopause relief could be linked to a heightened risk for brain tumors in some women, a new study warns.Depo-Provera (medroxyprogesterone acetate) increased.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Unlocking supernova stardust secrets

Science Daily: Pharmacology News

New research has discovered a rare dust particle trapped in an ancient extra-terrestrial meteorite that was formed by a star other than our sun.

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Puerto Rico Declares Dengue Epidemic as Cases Climb

Drugs.com

THURSDAY, MARCH 28, 2024 -- Puerto Rico has declared a dengue epidemic following a surge in cases of the mosquito-borne disease in the U.S. territory.In total, there have been 549 cases, including 341 hospitalizations and 29 severe cases, reported.

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Biotech veteran Art Krieg postpones retirement to build an unorthodox drug startup

BioPharma Drive: Drug Pricing

With Zola Therapeutics, Krieg plans to design and sell a series of cancer immunotherapies without the help of outside investors, he told BioPharma Dive.

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These 3 Factors Make Your Brain More Vulnerable to Dementia

Drugs.com

THURSDAY, March 28, 2024 -- Out of a host of possible risk factors for dementia, three really stood out in a new analysis: Diabetes, air pollution and alcohol.British and American researchers used brain scans to focus on a neurological network they.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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‘The heart is back,’ says Cardior CEO, as Novo’s $1B deal boosts field

BioPharma Drive: Drug Pricing

Novo Nordisk’s acquisition of Cardior Pharmaceuticals is a bet on new approaches to cardiovascular disease, says Cardior head Claudia Ulbrich.

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Just 30 Minutes Less Sitting Time Per Day Cuts Seniors' High Blood Pressure

Drugs.com

THURSDAY, March 28, 2024 -- Seniors wound up with lower blood pressure after they were coached to get up and move more often, a new study says.Health coaching successfully reduced sitting time for a group of older adults by just over 30 minutes a.

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Unlocking the potential of natural products in drug discovery

Drug Target Review

Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. 1 Surprisingly, however, less than one percent of the natural world’s chemical composition has been identified or studied by scientists. While plant-derived molecules (phytochemicals) have long played an essential role in drug discovery due to their diverse biological activities and chemical properties, the reliance on time-consuming and expensive screening techniques

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Too Often, Nearby Defibrillators Go Unused on People in Cardiac Arrest

Drugs.com

THURSDAY, March 28, 2024 -- There's been a big push over the past few years to get automated external defibrillators (AEDs) installed in public spaces, to help save lives threatened by cardiac arrest.Unfortunately, the devices are very seldom used.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Vector Space Biosciences: Leading Innovation in Space Medicine with AI

DrugBank

Space biosciences are on the verge of becoming one of the largest total addressable markets to ever exist, opening up vast opportunities for economic growth and scientific discovery.  In the realm of space exploration, one critical yet often overlooked aspect is the impact of space conditions on human health. The goal of sending humans to space for increasingly longer periods of time is contingent on our ability to ensure astronauts' health.

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Doctor Gets First U.S. Lung-Liver Transplant for Advanced Lung Cancer

Drugs.com

THURSDAY, March 28, 2024 -- Dr. Gary Gibbon didn’t have long to live. A harsh cocktail of chemotherapy, radiation and immunotherapy for his advanced lung cancer had permanently destroyed his lungs and caused irreparable damage to his.

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Navigating Market Access Challenges in Life Sciences Commercialization

Drug Channels

Today’s guest post comes from Bill Dupere, SVP of Product Development & Partnerships at Mercalis. Bill discusses specialty therapy access barriers, including payer utilization management techniques and “no coverage” policies. Contact Mercalis to learn about their Patient Support Services. Read on for Bill’s insights. Read more » © 2006-2024 HMP Omnimedia, LLC d/b/a Drug Channels Institute , an HMP Global Company.

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Living in Poor Neighborhoods Nearly Doubles Risk of Heart Attacks, Stroke

Drugs.com

THURSDAY, March 28, 2024 -- Living in a poor and unhealthy neighborhood could nearly double a person’s risk of heart disease and stroke, a new study says.The findings indicate that all the factors that make for a crummy neighborhood -- air and.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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FDA Approves Duvystat, New Oral Treatment for Duchenne Muscular Dystrophy (DMD)

PLOS: DNA Science

A new drug has entered the arsenal against Duchenne muscular dystrophy (DMD), a genetic disease that affects boys and is challenging to treat. Boys 6 years and older can take Duvystat, to slow the course of the illness. FDA classifies it as a “nonsteroidal treatment” – not a gene therapy, but it affects gene expression. DMD Basics DMD affects one in every 3500 to 6000 male births worldwide; that’s approximately 6 per 100,000 in North America and Europe, according to the M

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Good Sleep Can Make You Feel Young

Drugs.com

THURSDAY, March 28, 2024 -- A good night’s sleep can make you feel years younger, while crummy sleep leaves you doddering around like an oldster, a new study shows. Sleeping well enough to feel extremely sharp when you wake is associated with.

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Cream dosed drug patent expirations by year

Drug Patent Watch

This chart shows the patent expirations for cream dosed drugs over the next decade. The term of drug patents varies.

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Stressed? Some Genes Could Raise Your Heart Attack Risk

Drugs.com

THURSDAY, March 28, 2024 -- Folks with genetically-driven stress are more likely to suffer heart attacks after nerve-wracking events or times of unrest, a new study shows.People with above-average genetic scores linked to neuroticism and stress.

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Study explores the future of at-home cancer treatment

SCIENMAG: Medicine & Health

LOS ANGELES — A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.