Tue.Jan 28, 2025

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Ocean-surface warming four times faster now than late-1980s

Science Daily: Pharmacology News

The study helps explain why 2023 and early 2024 saw unprecedented ocean temperatures.

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Atalanta banks $97M to send RNAi drugs into the brain

BioPharma Drive: Drug Pricing

The startup says its specially constructed RNAi therapies can get deep into brain tissue, yielding new ways to treat neurological conditions like Huntington’s.

Therapies 132
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First mouse with two male parents to reach adulthood

Science Daily: Pharmacology News

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood. Their results describe how targeting a particular set of genes involved in reproduction allowed the researchers to overcome previously insurmountable challenges in unisexual reproduction in mammals.

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Enhertu, with new FDA OK, set to supplant chemo in HER2-low breast cancer

BioPharma Drive: Drug Pricing

The clearance is a step forward in AstraZeneca and Daiichi Sankyo’s plan to position antibody-drug conjugates like Enhertu ahead of chemotherapy in a variety of tumors.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Sharp look into Ockham's razor

Science Daily: Pharmacology News

A new article argues that by relying too much on parsimony in modeling, scientists make mistakes and miss opportunities.

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More Trending

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Relative of deadly Hendra virus found in the US

Science Daily: Pharmacology News

Researchers have identified the first henipavirus in North America.

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Weight Loss Boosts Long-Term Health of Kids With Obesity

Drugs.com

TUESDAY, Jan. 28, 2025 -- Helping kids with obesity drop pounds can have a huge impact on their future health.When these children and teens lose weight, they are less likely to have type 2 diabetes, high blood pressure and elevated cholesterol as.

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Follow the water: Searching for a lunar oasis

Science Daily: Pharmacology News

As humankind imagines living off-planet -- on the moon, Mars and beyond -- the question of how to sustain life revolves around the physical necessities of oxygen, food and water. We know there is water on the moon, but how do we find it? Researchers may help bring science fiction to reality by providing a divining rod to guide future space missions.

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Blood Test Accurately Detects Colon Cancer

Drugs.com

TUESDAY, Jan. 28, 2025 -- An experimental blood test can effectively and accurately detect colon cancer in middle-aged folks and seniors, a new study says.The blood test was 81% accurate in detecting colon cancer among people who have the disease.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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New clues to the mechanism behind food tolerance and allergies

Science Daily: Pharmacology News

Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases.

Disease 111
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Cover Image

Chemical Biology and Drug Design

Cover Image molekuul_be/Shutterstock.

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Moderate exercise keeps appetite at bay

Science Daily: Pharmacology News

A recent study has revealed that moderate-intensity exercise can significantly influence appetite-related hormones and perceptions in males with obesity.

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Heart Health Risk Factors Continue To Increase

Drugs.com

TUESDAY, Jan. 28, 2025 -- Major heart health risk factors like obesity, diabetes and high blood pressure remain on the rise in the United States, according to an annual report from the American Heart Association (AHA).These risks are thwarting.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Innovative one-minute video game boasts 80% success rate in diagnosing autism

Science Daily: Pharmacology News

A new one-minute video game is able to accurately and efficiently identify children with autism from those who have ADHD or are neurotypical.

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Noisy Settings OK For Blood Pressure Testing

Drugs.com

TUESDAY, Jan. 28, 2025 -- Dont worry if someones checking your blood pressure in a loud public place.The reading they get is apt to be just as accurate as if the test were taking place in a quiet, less stressful environment, researchers reported i.

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A super-Earth laboratory for searching life elsewhere in the Universe

Science Daily: Pharmacology News

Thirty years after the discovery of the first exoplanet, we detected more than 7000 of them in our Galaxy. But there are still billions more to be discovered! At the same time, exoplanetologists have begun to take an interest in their characteristics, with the aim of finding life elsewhere in the Universe. This is the background to the discovery of super-Earth HD 20794 d by an international team.

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Delayed Dream Sleep Linked to Alzheimer's Risk

Drugs.com

TUESDAY, Jan. 28, 2025 -- Delays in dreaming might be an early warning sign of Alzheimers disease.People who take significantly longer to enter the rapid eye movement (REM) phase of sleep could be experiencing an early symptom of Alzheimers, res.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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How simple prompts can make partially automated cars safer

Science Daily: Pharmacology News

A new study finds that prompts do a good job of getting drivers to engage with their environment and take over control of the vehicle when necessary while using partially automated driving systems -- with one exception. If drivers are deeply distracted, these system-generated prompts have little or no effect.

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Versant invests again in obesity, this time backing Helicore Biopharma

BioPharma Drive: Drug Pricing

Helicore, which is developing a GIP-blocking antibody, is the fourth obesity drug developer to receive Versant's backing in recent months.

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Towards a new generation of human-inspired language models

Science Daily: Pharmacology News

Can a computer learn a language the way a child does? A recent study sheds new light on this question. The researchers advocate for a fundamental revision of how artificial intelligence acquires and processes language.

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Qigong Effective In Easing Low Back Pain

Drugs.com

TUESDAY, Jan. 28, 2025 -- People with low back pain might want to look into the ancient Chinese mind-body movement exercise known as qigong, a new study published recently suggests.Qigong is similar to tai chi, in that it uses slow-flowing.

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Moon is not as 'geologically dead' as previously thought

Science Daily: Pharmacology News

Scientists developed advanced dating methods to track geological changes on the far side of the moon and found evidence of relatively recent activity.

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Rival radiopharma drug to Novartis’ Lutathera succeeds in trial, ITM says

BioPharma Drive: Drug Pricing

ITM's lutetium-containing therapy extended progression-free survival versus everolimus in patients with a specific kind of neuroendocrine tumor.

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A new register with thousands of entangled nuclei to scale quantum networks

Science Daily: Pharmacology News

In a groundbreaking achievement for quantum technologies, researchers have created a functional quantum register using the atoms inside a semiconductor quantum dot.

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New Viral Vectors - Winter 2025

addgene Blog

Bundling up for winter? The weather outside might be frightful, but browsing the 49 new preps available in the Addgene viral vector repository with a nice cup of hot chocolate is absolutely delightful. Grab a hot beverage and a blanket, then scroll on for some wintery delights!

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Immunogenicity Data Delivered Without Delay

Alta Sciences

Immunogenicity Data Delivered Without Delay blussier Tue, 01/28/2025 - 20:11 HTML Preclinical Assays for Immunogenicity Testing in Clinical Trials Whether developing a vaccine, biologic, or gene therapy, immunogenicity testing is required for regulatory approval and is critical for determining the safety and efficacy of your product. Our scientific experts will ensure your nonclinical assays are adapted and validated for your clinical trials, with a tailored bioanalytical program designed for yo

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seqr: Loading data from AnVIL

Broad Institute

seqr: Loading data from AnVIL By admin January 28, 2025 Breadcrumb Home seqr: Loading data from AnVIL Seqr is available for use on the NHGRI's Genomic Data Science Analysis, Visualization, and Informatics Lab-Space (AnVIL). AnVIL is powered by Terra, an analysis platform that allows researchers to access data, run analysis tools, and collaborate. This tutorial will show users how to request that a joint called vcf stored in Terra be loaded into seqr.

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