Science Daily: Pharmacology News
NOVEMBER 29, 2023
We humans are fixated on big brains as a proxy for smarts. But headless animals called brittle stars have no brains at all and still manage to learn through experience, new research reveals. These shy marine creatures have no brain to speak of -- just nerve cords running down each of their five wiggly arms. But that seems to be enough to learn by association, researchers report.
Chemical Biology and Drug Design
NOVEMBER 29, 2023
The co-administration of fenchone and sodium hyaluronate improved the body weight, number of fecal pellets, and fecal moisture in IBS-C rats. The ability of fenchone combined with sodium hyaluronate to regulate SCF/c-Kit signaling pathway, enhance intestinal barrier function, and modulate gut microbiota contributes to their efficacy in managing IBS-C.
Perficient: Drug Development
NOVEMBER 29, 2023
The Core of Efficiency: Choosing the Right ERP Choosing the right Enterprise Resource Planning (ERP) system is critical for ensuring optimal efficiency and future growth of your business. It is important to choose a system that seamlessly integrates with your unique processes and objectives, acting as the driving force behind your business operations.
Chemical Biology and Drug Design
NOVEMBER 29, 2023
An undescribed pyrrole alkaloid, Paphlagonicanin B and an undescribed flavonoid glycoside, Paphlagonicanin A. The most cytotoxic compound is 8 α - O -(2′,3′-dihydroxyisobutyryl) desacylcynaropicrin. Abstract Centaurea paphlagonica (Bornm.) Wagenitz is an endemic plant in Turkey. Pyrocatechol, vanillic acid, 3,4-dihydroxy benzoic acid, 5- O -caffeoylshikimic acid, tamarixetin, chlorogenic acid methyl ester, quercetin, 1,3-dicaffeoylquinic acid, tamarixetin-7- O - β -D-glucopyranoside, quercimetri
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
NOVEMBER 29, 2023
Bumpus, a former Johns Hopkins professor, named “creating a new model” for the FDA’s Office of Regulatory Affairs as one of her priorities when she steps into the role.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
Astronomers have found a key new system of six transiting planets orbiting a bright star in a harmonic rhythm. This rare property enabled the team to determine the planetary orbits which initially appeared as an unsolvable riddle.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Target Review
NOVEMBER 29, 2023
What does Ochre Bio do, can you give me an overview of your work? Our primary focus is to design and develop RNA therapies for liver diseases. Using humans as the model, we use an approach called deep phenotyping to explore the relationships between cells, genes, biological pathways and patterns of disease. Our team of chemists then uses this information to develop novel therapies.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- With fewer Americans dying from COVID in 2022, U.S. life expectancy rebounded a bit from declines experienced during the pandemic.According to provisional data from the U.S. Centers for Disease Control and Prevention on.
BioPharma Drive: Drug Pricing
NOVEMBER 29, 2023
Drawn-out negotiations led to a lower price than initially expected, but analysts called the agreement a step forward for the biotech company.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- People can walk away their risk of developing type 2 diabetes – but only if they walk fast enough, a new report finds.Folks who walk at least 2.5 miles an hour appear to have a significantly lower risk of type 2.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
NOVEMBER 29, 2023
The cuts will impact 7% of the cancer drug division’s employees, although about 90 new roles will be created around “areas of growth.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- U.S. suicide numbers reached a grim new high in 2022. The increase was most acute among women over the age of 24, according to provisional data from the U.S. Centers for Disease Control and Prevention. Overall, almost.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
While life on Earth is relatively new, geologically speaking, the ingredients that combined to form it might be much older than once thought. The simplest amino acid, carbamic acid, could have formed alongside stars or planets within interstellar ices. The findings could be used to train deep space instruments like the James Webb Space Telescope to search for prebiotic molecules in distant, star-forming regions of the universe.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- It's not just bumper-to-bumper highway traffic that's causing your blood pressure to spike during your daily commute.New research shows that the exhaust fumes spewing from all those vehicles triggers a significant.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
Bacterial vaginosis is a common condition in which the natural microbiome of the vagina falls out of balance, sometimes leading to complications in sexual and reproductive health. But exactly how these bacterial populations disrupt vaginal health has remained unclear.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- Dreary, chilly winter days might cause some year-round runners to think twice about their jog, but recent research suggests the benefits of cold weather running outweigh those of running in warmer.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
A new study provides compelling evidence that music preferences can serve as a window into an individual's moral values. It has uncovered an important link between music and morality, paving the way for a deeper understanding of the psychological dimensions of our musical experiences.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- Alzheimer’s patients are notoriously irritable, agitated and anxious – and researchers now think they know why.Brain inflammation appears to influence the mood problems of Alzheimer’s patients, rather than.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
A senior biology student at The University of Texas at Arlington recently earned an award for her research about antimicrobial drug resistance. Credit: The University of Texas at Arlington A senior biology student at The University of Texas at Arlington recently earned an award for her research about antimicrobial drug resistance.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
New research links soccer heading -- where players hit the ball with their head -- to a measurable decline in the microstructure and function of the brain over a two-year period.
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
Exercise may reduce postpartum depression, with moderate intensity exercises three to four times a week being especially effective, per meta-analysis Credit: Xu et al., CC-BY 4.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
Doctors managing deceased organ donors routinely treat the donors’ bodies with thyroid hormones in a bid to preserve heart function and increase the quantity and quality of hearts and other organs available for transplantation. However, according to a recent clinical trial led by researchers at Washington University School of Medicine in St.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 (Healthday News) -- The diabetes drug Mounjaro prompted more weight loss among overweight and obese adults than Ozempic did in a real-world setting, researchers report.Both Mounjaro (tirzepatide) and Ozempic (semaglutide).
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
Microgels form a thin protective shell around a droplet until the temperature rises above 32 degrees. Then the microgels shrink and the droplet dissolves in the surrounding liquid. A study by researchers from the University of Gothenburg now reveals the underlying mechanism behind this process.
Drugs.com
NOVEMBER 29, 2023
WEDNESDAY, Nov. 29, 2023 -- The world is being flooded with internet-driven misinformation, but there are ways to counter fake news with the facts, a new report says.These include aggressive fact-checking, preemptively debunking lies before they.
SCIENMAG: Medicine & Health
NOVEMBER 29, 2023
The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD).
Science Daily: Pharmacology News
NOVEMBER 29, 2023
In a remarkable discovery, astronomers have found a disc around a young star in the Large Magellanic Cloud, a galaxy neighboring ours. It's the first time such a disc, identical to those forming planets in our own Milky Way, has ever been found outside our galaxy. The new observations reveal a massive young star, growing and accreting matter from its surroundings and forming a rotating disc.
Cytel
NOVEMBER 29, 2023
A clinical trial is usually performed using some kind of comparator. This could be another drug on the market, or a customized formulation with the same characteristics as the drug formulation to be tested in the clinical trial — a placebo. Here I delve into developing your placebo and how to overcome common obstacles.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
A new bacterial species discovered at the deep-sea hydrothermal vent site 'Crab Spa' provides a deeper understanding of bacterial evolution.
Perficient: Drug Development
NOVEMBER 29, 2023
As oil and gas companies face a future of flux and rapid energy transition, remaining competitive requires either full-fledged digital transformation or major components of it. Specifically, automated workflows and connected worker solutions are improving the employee experience and productivity. Further, direct consumers are demanding digital experiences tailored to their expectations.
Science Daily: Pharmacology News
NOVEMBER 29, 2023
A landmark study into the geological timescale distribution of sediment and nutrients over 500 million years shows that species biodiversity on Earth is driven by landscape dynamics.
NIOSH Science Blog: Drugs
NOVEMBER 29, 2023
To survive and thrive in a fast-changing world, workers need to keep updating their skills to improve their employment chances, advance their careers, and meet the shifting needs of employers.1 Employers typically look for workers with proficiency in the technical and cognitive skills needed to do the job, but they also look for more portable and transferable skills (i.e., cross-sector competencies) that can be taken from job-to-job and transferred to different situations and social contexts, su
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