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Over the past 10 years, PD1-blocking medicines have transformed cancer care. But the steady expansion of their use has slowed and, despite much trying, pharmaceutical companies have largely failed to top the drugs’ successes.
In creating a pair of new robots, researchers cultivated an unlikely component, one found on the forest floor: fungal mycelia. By harnessing mycelia's innate electrical signals, the researchers discovered a new way of controlling 'biohybrid' robots that can potentially react to their environment better than their purely synthetic counterparts.
The funding comes amid a slowdown in venture investment for gene and cell therapy startups, and will support development of multiple solid tumor programs.
Researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells. Mice given the treatment had improved recovery from injuries, demonstrating potential for developing the therapy for people.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
WEDNESDAY, Sept. 4, 2024 -- An experimental three-in-one blood pressure pill works better than layering on meds one at a time, a new clinical trial shows.After a month on the combo pill, 81% of patients had their blood pressure under control.
Some per- and polyfluoroalkyl substances (PFAS) are poorly degradable and are also known as 'forever chemicals'. They adversely affect health and can lead to liver damage, obesity, hormonal disorders, and cancer. A research team has investigated the effects of PFAS on the brain. Using a combination of modern molecular biology methods and the zebrafish model, the researchers revealed the mechanism of action and identified the genes involved.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Some per- and polyfluoroalkyl substances (PFAS) are poorly degradable and are also known as 'forever chemicals'. They adversely affect health and can lead to liver damage, obesity, hormonal disorders, and cancer. A research team has investigated the effects of PFAS on the brain. Using a combination of modern molecular biology methods and the zebrafish model, the researchers revealed the mechanism of action and identified the genes involved.
TUESDAY, Sept. 4, 2024 -- An overgrowth of gut microorganisms that produce methane could be a cause of severe constipation in many people, a new review finds.These gut bugs belong to a class of microbe called archaea, and when they flourish too.
A new study shines a light on the enormous scale of uncollected rubbish and open burning of plastic waste in the first ever global plastics pollution inventory. Researchers used A.I. to model waste management in more than 50,000 municipalities around the world. This model allowed the team to predict how much waste was generated globally and what happens to it.
WEDNESDAY, Sept. 4, 2024 -- In news that should reassure folks glued to their cellphones all day, a new international review finds no link between cellphone use and brain cancer.Commissioned by the World Health Organization (WHO), the review.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
WEDNESDAY, Sept. 4, 2024 -- People who can cope with challenges as they grow older are more likely to live longer, a new study shows.Seniors with higher levels of mental resilience are 53% less likely to die within the next 10 years than those with.
Chemists offer a new explanation for how collagen in dinosaur bones may have survived millions of years: An atomic-level interaction prevents its bonds from being broken down by water.
WEDNESDAY, Sept. 4, 2024 -- Your cellphone might be harming your heart, a new study warns.People who regularly use a cellphone have a higher risk of heart disease, researchers found in a large-scale study.And the more time someone spends on their.
Researchers identified a mechanism for why some people will itch from an allergen or mosquito bite exposure, while others will not in a new study, and showed this pathway can be targeted to prevent allergic responses in preclinical models.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
WEDNESDAY, Sept. 4, 2024 -- A sweat-powered finger wrap could make monitoring a person’s health as easy as wearing a Band-Aid, researchers report.The electronic wrap measures blood levels of sugar, vitamins, drugs and other substances by analyzing t.
Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the methylation of their genetic material, which endowes these special astrocytes with stem cell properties. In mice, the researchers showed that experimentally induced lack of blood supply in the brain epigenetically reprograms astrocytes into brain stem cells, which in turn can give rise to nerve progenitor c
WEDNESDAY, Sept. 5, 2024 -- Weather patterns in California that have been exacerbated by climate change could be fueling more cases of a dangerous fungal infection, scientists warn.The Coccidioides fungus lives in soil, where it can be picked up by.
An atmospheric river brought warm, moist air to the coldest and driest corner of the planet in 2022, pushing temperatures 70 degrees above average. A new study reveals what happened to Antarctica's smallest animals.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
WEDNESDAY, Sept. 4, 2024 -- A new brain imaging study has concluded that autism likely isn’t caused by faulty connections to the amygdala.A prevailing hypothesis of autism spectrum disorder has held that people with the condition have poorer neural.
Nuclear clocks would measure time based on changes inside an atom's nucleus, which would make them less sensitive to external disturbances and potentially more accurate than atomic clocks. These clocks could lead to improved timekeeping and navigation, faster internet speeds, and advances in fundamental physics research. Scientists have demonstrated key components of a nuclear clock, such as precise frequency measurements of an energy jump in a thorium-229 nucleus.
WEDNESDAY, Sept. 4, 2024 -- Current vaccines against mpox were designed to fight an older, rarer cousin of the virus, smallpox.Now, new research from the drug company Moderna suggests its new mpox vaccine, based on mRNA technology, might do a.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Some of the butterflies most in danger of fluttering out of existence fare better when their habitats are actively managed by humans, a recent study found. Scientists have long warned that insect populations worldwide are falling rapidly due to the combined effects of climate change, habitat loss and pesticides. The study analyzed data on 114 populations of 31 butterfly species in 10 U.S. states.
It's 7 billion years ago, and the universe's heyday of star formation is beginning to slow. What might our Milky Way galaxy have looked like at that time? Astronomers have found clues in the form of a cosmic question mark, the result of a rare alignment across light-years of space.
A new dose regimen of Biogen's spinal muscular atrophy drug appeared promising, while Denali Therapeutics and Regenxbio charted plans for drug approval applications.
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