Drug Discovery Today
OCTOBER 7, 2024
Researchers from the Institute of Biotechnology at the Life Sciences Center of Vilnius University – Dalia Smalakyte, Audrone Rukšenaite, Dr Giedrius Sasnauskas, Dr Giedre Tamulaitiene, and Dr Gintautas Tamulaitis – have revealed the structure of the CRISPR-Cas "protein scissors" found in bacteria and provided mechanistic details on how they function.
BioPharma Drive: Drug Pricing
OCTOBER 7, 2024
The Cambridge, Massachusetts-based biotech is using what it calls ligand-siRNA conjugates to reach drug targets in the kidney, which historically have been difficult to reach with RNA therapies.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- Even as folks in North Carolina continue to clean up following the devastation of Hurricane Helene, a new health danger has emerged: The massive flooding that swept away roads and towns also uprooted the underground nests of.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Researchers conclude that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- Checking your blood pressure at home? Pay attention to arm position. A new study by Johns Hopkins researchers confirms that it makes a "huge difference" when it comes to getting an accurate measurement. And, the authors add.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Researchers have made the surprising discovery that one species of comb jelly (Mnemiopsis leidyi) can fuse, such that two individuals readily turn into one following an injury. Afterwards, they rapidly synchronize their muscle contractions and merge digestive tracts to share food.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Planet-forming disks, maelstroms of gas and dust swirling around young stars, are nurseries that give rise to planetary systems, including our solar system. Astronomers have discovered new details of gas flows that sculpt those disks and shape them over time.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- A pair of American scientists have won the 2024 Nobel Prize in medicine for their discovery of microRNA, tiny genetic molecules that play a crucial role in how genes shape the body. The research of Victor Ambros and Gary.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Researchers have discovered the most distant Milky-Way-like galaxy yet observed. Dubbed REBELS-25, this disc galaxy seems as orderly as present-day galaxies, but we see it as it was when the Universe was only 700 million years old. This is surprising since, according to our current understanding of galaxy formation, such early galaxies are expected to appear more chaotic.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- A simple blood test may help doctors decide the best way to treat a man with advanced prostate cancer. A phase 3 clinical trial has shown that circulating tumor cell (CTC) counts can predict which men are likely to respond.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Scientists have discovered the secret to regulating our internal clock. They identified that this regulator sits right at the tail end of Casein Kinase 1 delta, a protein which acts as a pace setter for our internal biological clock or the natural 24-hour cycles that control sleep-wake patterns and other daily functions, known as circadian rhythm.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- Chemicals called phenols include food preservatives, plastics ingredients such as BPA and the parabens in shampoos, so they are ubiquitous in everyday life.Now, research suggests that higher exposure to phenols might trigger.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Over the past decade, decreasing vaccination rates now threaten the huge beneficial impacts of vaccinations in the U.S. and globally. Researchers discuss the multifactorial barriers including increasing vaccine hesitancy and new clinical and public health challenges in vaccinations of U.S. adults.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- Generations of parental warnings may not be wrong: A massive study of available data finds teens who use marijuana have significantly worse outcomes at school. Data from 63 studies involving almost 440,000 youths found.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Vegetation cover across the Antarctic Peninsula has increased more than tenfold over the last four decades, new research shows.
Drug Patent Watch
OCTOBER 7, 2024
Pharmacokinetics (PK) plays a crucial role in the development and approval of generic drugs. PK studies help ensure that generic drugs are bioequivalent to their brand-name counterparts, meaning they have similar absorption, distribution, metabolism, and excretion (ADME) profiles.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Never before have people recorded more information about their lives than today. But what does this mean for the way we remember our lives and how we talk about them? Researchers are trying to find answers to these questions.
Collaborative Drug
OCTOBER 7, 2024
What is a Structure Activity Relationship? Structure Activity Relationships (SAR) can be used to predict biological activity from molecular structure. This powerful technology is used in drug discovery to guide the acquisition or synthesis of desirable new compounds, as well as to further characterize existing molecules. Predicting Biological Activity from Structure The biological effects of a new chemical compound can often be predicted from its molecular structure using data about other simila
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- Two new studies show insurers continue to deny claims for preventive care that is supposed to be free under Obamacare.And insurers are more apt to reject claims from patients who are Asian, Black or Hispanic as well as those.
Science Daily: Pharmacology News
OCTOBER 7, 2024
Researchers have discovered a natural immune mechanism in mice that stops escaped cancer cells from developing into tumors elsewhere in the body.
Collaborative Drug
OCTOBER 7, 2024
Chemical registration is the most critical part of your discovery engine. If you are working without a chemical registration system (or avoiding your unwieldy legacy solution), you may be missing the full value of your data – wasting time and money. CDD Vault harmonizes your compound collection and ties it to your screening data, allowing you to track screening results across compounds and families of compounds.
Science Daily: Pharmacology News
OCTOBER 7, 2024
NASA's Curiosity rover, currently exploring Gale crater on Mars, is providing new details about how the ancient Martian climate went from potentially suitable for life -- with evidence for widespread liquid water on the surface -- to a surface that is inhospitable to terrestrial life as we know it.
Drug Channels
OCTOBER 7, 2024
Informa Connect’s PBM Contracting Summit December 10-11, 2024 | Chicago, IL Drug Channels readers save 10% with code 24DRCH10 * Experts from across the US come together each year at the PBM Contracting Summit to gain innovative and practical contracting strategies, master PBM innovation and design, improve patient care management and rising costs, understand the current legislative issues impacting contract negotiations and more.
BioPharma Drive: Drug Pricing
OCTOBER 7, 2024
The study, of Intellia’s treatment for hereditary angioedema, is the second Phase 3 trial the biotech has begun testing its “in vivo” gene editing medicines.
FDA Law Blog: Biosimilars
OCTOBER 7, 2024
By JP Ellison & Anne K. Walsh — It took only 3 months. In June, the Supreme Court ruled that the SEC cannot use its administrative authority to impose civil penalties for securities fraud on the ground that these penalties violate the U.S. Constitution’s Seventh Amendment right to a jury trial. See SEC v Jarkesy , 144 S. Ct. 2117 (2024). The Court reasoned that the SEC’s civil penalties “are designed to punish and deter, not compensate,” and that they are a remedy “that could only be enfo
BioPharma Drive: Drug Pricing
OCTOBER 7, 2024
Phase 3 findings could position the biotech’s therapy to become part of a “new standard” for SMA, its CEO said, while boosting research into whether it can preserve muscle in people with obesity.
Fierce BioTech
OCTOBER 7, 2024
Authors:Kirk Harmon, Vice President & GM, Contract Sales Organization, IQVIAJavier “Jave” Castillo, R.Ph, Vice President, CSO Strategy, IQVIA | Transform your commercial model with IQVIA’s tailored contract sales solutions, driving growth and optimizing margins, powered by data-driven insights.
BioPharma Drive: Drug Pricing
OCTOBER 7, 2024
The company is committing to make at least 2 million doses of its long-acting PrEP therapy available in low- and middle-income countries next year and in 2026.
Perficient: Drug Development
OCTOBER 7, 2024
Unlock Your Website’s Potential with Custom Fonts In this blog, we’ll explore the importance of typography in enhancing your site’s visual appeal and user experience. You’ll discover step-by-step instructions for integrating custom fonts into your Optimizely CMS Spire. Whether you’re a beginner or an experienced developer, this guide will provide valuable insights to elevate your web design.
Alta Sciences
OCTOBER 7, 2024
Inside The Altascientist Issue 40: Analytical Testing–Accurate and Complete Characterization of Your API to Maximize Bioavailability pmjackson Mon, 10/07/2024 - 20:20 In Issue 40 of The Altascientist , different analytical testing techniques to support drug product development specific to bioavailability are explored, including a case study on the manufacturing of a nanosuspension.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- So much for the idea that most people born today will live 100 years or more. New research shows that the dramatic increases in life expectancy seen during the 19th and 20th centuries have slowed considerably. In the.
Perficient: Drug Development
OCTOBER 7, 2024
Meet Andrea Milano, Principal of Perficient’s Data and Analytics Business Unit Andrea Milano is a dynamic leader in the Data and Analytics practice at Perficient who drives growth and opens doors for the company, her colleagues, and her own career. In her role as Principal, Andrea oversees project delivery, mentors and manages colleagues, and works with a diverse, cross-industry selection of clients.
Drugs.com
OCTOBER 7, 2024
MONDAY, Oct. 7, 2024 -- A Wisconsin program that sends suspects in minor drug-related crimes to treatment instead of jail is paying off, a new study shows.Researchers who evaluated the Madison Area Recovery Initiative (MARI) found that non-violent.
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