Science Daily: Pharmacology News

AUGUST 22, 2024

Non-living hydrogels can play the video game Pong and improve their gameplay with more experience, researchers report. The researchers hooked hydrogels up to a virtual game environment and then applied a feedback loop between the hydrogel's paddle -- encoded by the distribution of charged particles within the hydrogel -- and the ball's position -- encoded by electrical stimulation.

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Research 142

Chemical Biology and Drug Design

AUGUST 22, 2024

TQ enhanced DOX sensitivity in U87 glioblastoma cells via targeting PI3K/Akt/mTOR signaling. Abstract Natural compounds such as thymoquinone (TQ) have recently gained increasing attention in treating glioblastoma (GBM). However, the effects of TQ in reversing drug resistance are not completely understood. Therefore, we aimed to examine TQ impacts on GBM cells with doxorubicin (DOX) resistance and the involvement of the PI3K/Akt/mTOR pathway.

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Treatment Drugs Research 100

Science Daily: Pharmacology News

AUGUST 22, 2024

A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm.

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DNA 138

ASPET

AUGUST 22, 2024

Neuropathic pain is a form of chronic pain that develops because of damage to the nervous system. Treatment of neuropathic pain is often incompletely effective, and most available therapeutics have only moderate efficacy and present side effects that limit their use. Opioids are commonly prescribed for the management of neuropathic pain despite equivocal results in clinical studies and significant abuse potential.

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Treatment Drugs 100

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- Updated shots to shield against COVID-19 infection were approved by the U.S. Food and Drug Administration on Thursday.This year's approval for the updated mRNA vaccines comes much sooner than happened in 2023, when fall.

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FDA Approval FDA Vaccine Drugs 116

Science Daily: Pharmacology News

AUGUST 22, 2024

Parental bed-sharing is unlikely to impact children's psychological development, new research has found. The study looked at nearly 17,000 British babies and tracked them for 11 years -- finding kids who shared beds were happy and healthy.

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Research 121

Science Daily: Pharmacology News

AUGUST 22, 2024

While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year.

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Virus Disease 124

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- High levels of fluoride in drinking water may dim the intelligence of children, a new U.S. government report shows. Based on an analysis of published research, the potentially controversial report marks the first time a.

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Government Research 111

Science Daily: Pharmacology News

AUGUST 22, 2024

Researchers have developed a sprayable gel that creates a shield to protect buildings from wildfire damage. It lasts longer and is more effective than existing commercial options.

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Research 116

BioPharma Drive: Drug Pricing

AUGUST 22, 2024

The approval of both reformulated messenger RNA vaccines, which are designed to target the KP.2 virus strain, comes just ahead of the fall and winter seasons.

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RNA FDA Virus Vaccine 113

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- A drug under development could provide a much needed option for women seeking relief from hot flashes and other menopausal symptoms, new research shows.The drug, elinzanetant, cut the frequency of hot flashes by an.

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Research Drugs 111

Science Daily: Pharmacology News

AUGUST 22, 2024

New research has systematically demonstrated that a mild zap of electricity can strengthen a marine coastline for generations -- greatly reducing the threat of erosion in the face of climate change and rising sea levels. The new process forms natural cement between grains of sand, transforming it into solid, immoveable rock. Mollusks use a similar process to turn naturally occurring minerals into shells.

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Research 109

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 21, 2024 -- Type 2 diabetes increased by nearly 20% in the United States between 2012 and 2022, with age, race, income level, obesity and lack of exercise all playing a role in the metabolic disease’s spread, a new study r.

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Science Daily: Pharmacology News

AUGUST 22, 2024

Researchers have demonstrated a technology capable of a suite of data storage and computing functions -- repeatedly storing, retrieving, computing, erasing or rewriting data -- that uses DNA rather than conventional electronics. Previous DNA data storage and computing technologies could complete some but not all of these tasks.

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DNA Research 108

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- COVID cases have surged this summer, but a new study suggests that following the Mediterranean diet might spare you from infection.In a review published Wednesday in the journal PLOS One, Indonesian researchers discovered.

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Research 105

Science Daily: Pharmacology News

AUGUST 22, 2024

The state of fish stocks in the world's ocean is worse than previously thought. While overfishing has long been blamed on fisheries policies that set catch limits higher than scientific recommendations, a new study reveals that even these scientific recommendations were often too optimistic. The result? Far more global fish stocks are overfished or have collapsed than we thought.

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Research 106

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- Kids and teens are vulnerable to Long COVID just as adults are, with a set of distinct symptoms showing long-term health effects, a new study shows.Ten symptoms in school-age children and 8 in teenagers indicate the.

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Science Daily: Pharmacology News

AUGUST 22, 2024

Scientists report incredibly small time delays in a molecule's electron activity when the particles are exposed to X-rays. To measure these tiny high-speed events, known as attoseconds, researchers used a laser to generate intense X-ray flashes that allowed them to map the inner workings of an atom.

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Research 104

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- People stricken with a severe case of COVID-19 have a higher risk of mental illness in the year following their infection, a new study warns.However, vaccination appears to ward off these effects on mental health.

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Vaccine 103

Science Daily: Pharmacology News

AUGUST 22, 2024

Primate ornamentation plays a crucial role in communication not only within social groups but also between them, according to a new study. The research reveals that the males of species with overlapping home ranges often display vibrant colors or elaborate features, traits that may help reduce intergroup aggression by enabling quick assessments of potential rivals.

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Research 103

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- A wedding band may be good medicine for men as they age, but not so much for women, new research shows. A three-year study of over 7,600 Canadians aged 60 and older found that men who got hitched were twice as likely to.

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Research 102

addgene Blog

AUGUST 22, 2024

If you’ve ever run a western blot , or thought about running one, you’ll know there’s a lot of choices to make when designing the experiment. What detection method? What membrane? What should you block with?

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NIOSH Science Blog: Drugs

AUGUST 22, 2024

When thinking of mining, many picture male coal miners. This is because most miners are men, and many depictions of coal miners are of men wearing hardhats and dusty reflective coveralls. Women have been working in various capacities above ground in coal mining since coal was first commercially used in the U.S. in the early 1700s. However, it wasn’t until 1974 that women were formally recognized and included in the underground coal mining workforce.

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Research 73

BioPharma Drive: Drug Pricing

AUGUST 22, 2024

The FDA backed Jeff Shuren, the agency’s former CDRH leader, amid questions raised by The New York Times. Still, a spokesperson said the FDA has advised Shuren to take greater caution in managing recusal obligations.

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FDA 67

Collaborative Drug

AUGUST 22, 2024

Burlingame, California – August 22, 2024 – Collaborative Drug Discovery (CDD), provider of CDD Vault, a web-based scientific research informatics platform, is excited to announce the launch of the CDD AI Support ChatBot, a cutting-edge capability to enhance the user support experience by offering immediate responses to common customer support inquiries.

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Drugs Research 94

Science Daily: Pharmacology News

AUGUST 22, 2024

A new flu vaccine candidate incorporates proteins from 8 strains of influenza.

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Vaccine 110

BioPharma Drive: Drug Pricing

AUGUST 22, 2024

Borealis Biosciences launches with money from Novartis, which last year bought the biotech’s predecessor for a pair of drugs that treat a rare kidney disorder.

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Drugs 67

Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 (HeathDay News) -- There's a strong association between a state's policies and laws around the rights of transgender people and the mental health of transgender residents, a new study shows."Trans individuals who were worried.

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BioPharma Drive: Drug Pricing

AUGUST 22, 2024

Leqembi’s benefits are “too small to justify the significant cost to the NHS,” said the head of a UK agency in charge of determining medicine reimbursement.

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Drug Patent Watch

AUGUST 22, 2024

Effective project management is crucial for the success of any contract development and manufacturing organization (CDMO). As a dedicated CDMO, we understand the importance of providing outstanding services, solutions, and support to our clients.

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Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- Suicide rates among female doctors are significantly higher than those of the general population, a new study finds.Female doctors have a 76% higher suicide risk than average folks, researchers found.Male doctors had.

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Doctors Research 59

Science Daily: Pharmacology News

AUGUST 22, 2024

The largest dataset of cetacean genes ever collated has helped scientists deep dive 'into the blue' to fathom the 'triumph' of baleen whale evolution. The new study explores the key genetic adaptations of these diverse whale species around the world's vast oceans -- giving new insights into the risks and opportunities for their survival.

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Drugs.com

AUGUST 22, 2024

THURSDAY, Aug. 22, 2024 -- Most Americans believe artificial intelligence should be used to improve health care, a new national survey reports.However, many are still a little queasy over some of the implications of widespread AI use, the poll.

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PLOS: DNA Science

AUGUST 22, 2024

I eagerly awaited publication of the novel Eruption , the brainchild of the late, great Michael Crichton and James Patterson, a master storyteller whose trademark staccato sentences and short chapters propel his thrillers. Crichton authored 28 novels, Patterson more than 200. The Associated Press deemed Eruption “a seismic publishing event.” Proclaimed BookBub, “an “instant #1 New York Times bestseller was in the cards the moment James Patterson agreed to complete Michael

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DNA Virus Organic Chemistry Science 52