Thu.Mar 21, 2024

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Two of the Milky Way's earliest building blocks identified

Science Daily: Pharmacology News

Astronomers have identified what could be two of the Milky Way's earliest building blocks: Named 'Shakti' and 'Shiva', these appear to be the remnants of two galaxies that merged between 12 and 13 billion years ago with an early version of the Milky Way, contributing to our home galaxy's initial growth. The new find is the astronomical equivalent of archeologists identifying traces of an initial settlement that grew into a large present-day city.

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As Treatments Ease Anxiety, Heart Risks Also Decline

Drugs.com

THURSDAY, March 21, 2024 -- People with heart disease can stay healthier if they address their emotional problems as well as their physical ailments, a new study says.Treating anxiety and depression reduced ER visits and hospitalizations among.

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Say hello to biodegradable microplastics

Science Daily: Pharmacology News

Finding viable alternatives to traditional petroleum-based plastics and microplastics has never been more important. New research shows that their plant-based polymers biodegrade -- even at the microplastic level -- in under seven months.

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U.S. Life Expectancy Rose Overall, But Overdose Deaths Still Set Records

Drugs.com

THURSDAY, March 21, 2024 -- As the pandemic wound down, life expectancy in the United States began to bounce back in 2022, although deaths among children increased and drug overdose deaths continued to reach record highs, new government research.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Decoding the plant world's complex biochemical communication networks

Science Daily: Pharmacology News

A research team has begun translating the complex molecular language of petunias. Their grammar and vocabulary are well hidden, however, within the countless proteins and other compounds that fill floral cells. Being rooted to the ground, plants can't run away from insects, pathogens or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds.

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NextCure to lay off 37% of staff, dial back research plans

BioPharma Drive: Drug Pricing

The job cuts at the cancer drug developer will primarily impact manufacturing roles, but will touch on several other parts of the organization, the company said.

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More Trending

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We’re All Outraged! Turning Passion into Results.

Perficient: Drug Development

If you were to pop open any social media platform or news app right now and scroll through a couple dozen posts, you’ll easily get the feeling that everything is #%&$ falling apart. Everyone is mad at something. We now use the term “doomscrolling.” In the past we had Yellow Journalism and we are there once again. As humans we tend to get addicted to outrage and drama.

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Knitting Helps Keep Troubled Minds From Unraveling, Study Finds

Drugs.com

THURSDAY, March 21, 2024 — Stressed out, anxious or desperately needing to recharge?Grab some knitting needles and a pretty ball of yarn — Swedish research shows yarncraft improves mental health without medication."Knitters have a creative.

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Rays were more diverse 150 million years ago than previously thought

Science Daily: Pharmacology News

Scientists have explored the puzzling world of rays that lived 150 million years ago and discovered a previously hidden diversity -- including a new ray species. This study significantly expands the understanding of these ancient cartilaginous fish and provides further insights into a past marine ecosystem.

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Yes, You Should Clean That Water Bottle, and Here's How

Drugs.com

THURSDAY, March 21, 2024 -- Does your water bottle only get washed once or twice a week -- or even less?Time to switch things up: Even a day or two without washing can encourage the growth of unhealthy germs in the average water bottle, one expert.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Older Siblings Made Possible Just-Approved Gene Therapy for Metachromatic Leukodystrophy

PLOS: DNA Science

The Food and Drug Administration just announced approval of Lenmeldy (atidarsagene autotemcel), a gene therapy to treat the neurological condition metachromatic leukodystrophy (MLD). Available in Italy for three years, Lenmeldy (atidarsagene autotemcel), from Orchard Therapeutics, is groundbreaking, but comes at quite a cost – the $4.25 million price tag for the one-time infusion, and for the older siblings who contributed to developing the gene treatment, but were too sick to receive it.

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Skin Biopsy Might Help Diagnose Parkinson's or Other Brain Disorders

Drugs.com

THURSDAY, March 21, 2024 -- Folks can learn their risk for Parkinson’s disease and other related brain disorders through a simple skin biopsy, a new study says.Skin tests can detect an abnormal form of alpha-synuclein, a protein that is the.

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Illuminating Choices: A Guide to Selecting Fluorescent Dyes and Ligands

addgene Blog

Throughout their history, fluorescent dyes have enabled the visualization of both organic tissues and cell cultures, opening biological interiors to many inquisitive scientists. Seeing inside these specimens has offered illumination on biochemical processes that are crucial in the world of biological research, medical therapy, and even drug development (Grimm & Lavis, 2022).

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A Bacteria in the Mouth Might Speed Colon Cancers

Drugs.com

THURSDAY, March 21, 2024 -- A germ commonly found in the human mouth can travel to colon tumors and appears to speed their growth, new research shows.The finding might lead to new insights into fighting colon cancer, which kills more than 52,000.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Thermo Fisher, Bayer partner to develop companion diagnostics

BioPharma Drive: Drug Pricing

The companies aim to identify potential patients for Bayer’s precision cancer therapies and increase access to the treatments.

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COVID-19's Damage to Organs Can Harm Heart, Too

Drugs.com

THURSDAY, March 21, 2024 -- COVID-19 can damage a person’s heart even if the coronavirus doesn’t directly infect the heart tissue, a new study has found.The severe inflammation that COVID causes in other organs, like the lungs, appears to.

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Mirador debuts with $400M, picking up where immune drugmaker Prometheus left off

BioPharma Drive: Drug Pricing

The financing for the startup, which is led by former executives of a biotech Merck recently bought for nearly $11 billion, is the sector’s largest for a privately held company this year.

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Flu May Be Tougher on Brain Health Than COVID-19: Study

Drugs.com

THURSDAY, March 21, 2024 — The flu is more likely to lead to a neurological disorder than COVID, according to a new study that surprised its authors. "While the results were not what we expected to find, they are reassuring in that we found.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Morality among low-risk differentiated thyroid cancer survivors in the U.S.

SCIENMAG: Medicine & Health

A new study has shown that overall and cause-specific mortality rates in individuals in the U.S. with low-risk differentiated thyroid cancer (DTC) are low. The study is published in the peer-reviewed journal Thyroid®, the official journal of the American Thyroid Association® (ATA®). Click here to read the article now. Credit: Mary Ann Liebert, Inc.

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Fertility Will Fall in Most Nations Over Future Decades

Drugs.com

THURSDAY, March 21, 2024 -- By 2050, three-quarters of the world's nations will see fertility rates fall to below replacement levels, meaning their populations will be steadily shrinking, a new study predicts. And by 2100, almost all countries.

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Immune cells identified as key players in brain health

SCIENMAG: Medicine & Health

New York, NY [March 21, 2024]—Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer’s and other diseases.

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Don't Use 'Comfi' Baby Walkers Due to Injury Dangers

Drugs.com

THURSDAY, March 21, 2024 -- Your baby could be endangered by now-recalled Comfi Baby Infant Walkers, the Consumer Product Safety Commission (CPSC) warned Thursday.The walkers, sold on Amazon, "violate the federal safety regulations for infant.

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NSF awards grant for evolution-inspired design of therapeutic RNAs

SCIENMAG: Medicine & Health

A team led by Dr. Samie Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a three-year, $1.65 million grant for RNA research under a biotechnology-development program run by the U.S. National Science Foundation. Credit: Credit: John Abbott A team led by Dr.

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Roche autoimmune disease drug disappoints in closely watched trial

BioPharma Drive: Drug Pricing

Though the medicine hit its goal in a Phase 3 study in myasthenia gravis, the results fell short of expectations in a boost to rival drug developers like Argenx and AstraZeneca.

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Mark Cuban: Five Ways that Big PBMs Hurt U.S. Healthcare–And How We Can Fix It

Drug Channels

Today’s guest post comes from Mark Cuban, co-founder of the Mark Cuban Cost Plus Drug Company A few weeks ago, Mark participated in the White House Roundtable on Lowering Healthcare Costs and Bringing Transparency to Prescription Drug Middlemen. I found Mark’s comments to be intriguing and highly provocative, so I invited him to publish an edited version exclusively here on Drug Channels.

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Secrets of the Van Allen belt revealed in new study

Science Daily: Pharmacology News

A challenge to space scientists to better understand our hazardous near-Earth space environment has been set in a new study.

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Common Epilepsy, Migraine Drug Topiramate Won't Raise Odds for Autism in Offspring

Drugs.com

THURSDAY, March 21, 2024 -- A common antiseizure drug used to treat epilepsy, migraines and bipolar disorder does not appear to increase the risk of autism for kids exposed to it in the womb, a new study says. Topiramate does not contribute to any.

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Developing an mRNA therapy for Duchenne muscular dystrophy

Drug Target Review

How does the mechanism of action of Bobcat mRNA TM differ from traditional exon-skipping drugs and AAV-microdystrophin in treating Duchenne muscular dystrophy? Bobcat mRNA TM is a proprietary linear mRNA technology designed for the highly efficient and cost-effective production of high-quality mRNA encoding large proteins (over 13 kb). It is delivered via a lipid nanoparticle (LNP).

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Perficient Recognized in Forrester’s Automation Fabric Services Landscape, Q1 2024 Report

Perficient: Drug Development

In an era where automation plays a pivotal role in reshaping businesses, selecting the right partner for automation fabric services is critical. Forrester’s report, The Automation Fabric Services Landscape, Q1 2024, offers insights into the evolving landscape and recognizes notable providers in the industry. Perficient is listed among these notable providers as a large automation fabric consultancy, with an industry focus in financial services, healthcare, and manufacturing/production of c

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Bayer streamlines pharma leadership team amid company shakeup

BioPharma Drive: Drug Pricing

The executive team will reportedly shrink from 14 to eight in the latest step in new CEO Bill Anderson’s plan to slash management and reduce “bureaucracy” at the healthcare conglomerate.

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Conference Notebook: ACI’s Cosmetics and Personal Care Products Conference

FDA Law Blog: Biosimilars

By John W.M. Claud — The American Conference Institute’s 11th Annual Legal, Regulatory, and Compliance Forum on Cosmetics & Personal Care Products took place this week in New York, and featured a full house of folks talking about the Modernization of Cosmetics Regulation Act (MoCRA) , the legal considerations around making environmental, sustainable, and green (ESG) claims, and the impact of state laws.

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How to Upgrade Standard Einstein Bot into Enhanced Bot?

Perficient: Drug Development

Hello Trailblazers… Welcome to the Series of Salesforce Einstein Chatbots! Part 3 In the ever-evolving landscape of customer engagement, providing seamless and personalized experiences has become paramount. With Salesforce’s Einstein Bots, businesses can leverage the power of AI-driven conversations to elevate their customer interactions. However, as needs grow more complex, the demand for more advanced bot capabilities rises.

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Common Epilepsy, Migraine Drug Won't Raise Odds for Autism in Offspring

Drugs.com

THURSDAY, March 21, 2024 -- A common antiseizure drug used to treat epilepsy, migraines and bipolar disorder does not appear to increase the risk of autism for kids exposed to it in the womb, a new study says.Topiramate does not contribute to any.

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