Sat.Jan 20, 2024

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Expanding the ligandable proteome by paralog hopping with covalent probes

Covalent Modifiers

Yuanjin Zhang , Zhonglin Liu , Marsha Hirschi , Oleg Brodsky , Eric Johnson , Sang Joon Won , Asako Nagata , Matthew D Petroski , Jaimeen D Majmudar , Sherry Niessen , Todd VanArsdale , Adam M Gilbert , Matthew M Hayward , Al E Stewart , Andrew R Nager , Bruno Melillo , Benjamin F Cravatt bioRxiv 2024.01.18.576274; doi: [link] More than half of the ~20,000 protein-encoding human genes have at least one paralog.

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New patent expiration for Pfizer drug ZAVZPRET

Drug Patent Watch

Annual Drug Patent Expirations for ZAVZPRET Zavzpret is a drug marketed by Pfizer and is included in one NDA. It is available from two suppliers. There are three patents protecting… The post New patent expiration for Pfizer drug ZAVZPRET appeared first on DrugPatentWatch - Make Better Decisions.

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1-Equitable Use: Universal Design Principle Series

Perficient: Drug Development

Welcome to the first installment of our Universal Design Principle Series. Today, we embark on a journey of exploration and understanding, starting with the foundational principle of Equitable Use. Join us as we delve into the essence of inclusive design, unraveling the principles that pave the way for a world that caters to the needs of everyone, regardless of ability or background.

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Tips to Help Your Skin Thrive This Winter

Drugs.com

SATURDAY, Jan. 20, 2024 — Winter isn't kind to your skin.Dry, cold weather causes dryness, and you might even develop "winter rash" — dry, irritated skin that's red, bumpy, flaky and burns. That's why it's prime time to step up your skin care.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Which pharmaceutical drugs have the most drug patents in Russian Federation?

Drug Patent Watch

This chart shows the drugs with the most patents in Russian Federation. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is… The post Which pharmaceutical drugs have the most drug patents in Russian Federation? appeared first on DrugPatentWatch - Make Better Decisions.

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#ScienceSaturday: January 20, 2024

KIF1A

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KAND Resources KAND is a complex disorder, and each patient may experience a wide variety of symptoms that require evaluation by different specialists.

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