Fri.Feb 21, 2025

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Brain-wide activity change visualized as geometric patterns

Science Daily: Pharmacology News

Researchers have applied a visualization technique to depict the brain's activity related to visual perception as geometric patterns. They visualized different shapes as the ever-changing neuronal activity in the temporal and frontal lobes of the brain during object recognition and recalling memories. This achievement promises further extraction of brain activity observed in various aspects of daily life.

Research 302
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Site-specific activation of the proton pumpinhibitor rabeprazole by tetrathiolate zinccentres

Covalent Modifiers

Teresa Marker, Raphael R. Steimbach, Cecilia Perez-Borrajero, Marcin Luzarowski, Eric Hartmann, Sibylle Schleich, Daniel Pastor-Flores, Elisa Espinet, Andreas Trumpp, Aurelio A. Teleman, Frauke Grter, Bernd Simon, Aubry K. Miller & Tobias P. Dick Nat. Chem. ( 2025 ). [link] Proton pump inhibitors have become top-selling drugs worldwide. Serendipitously discovered as prodrugs that are activated by protonation in acidic environments, proton pump inhibitors inhibit stomach acid secretion by cov

Drugs 147
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How to get a robot collective to act like a smart material

Science Daily: Pharmacology News

Researchers are blurring the lines between robotics and materials, with a proof-of-concept material-like collective of robots with behaviors inspired by biology.

Research 329
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Bluebird, at risk of default, agrees to take-private deal

BioPharma Drive: Drug Pricing

The pioneering gene therapy developer will be acquired by investment firms Carlyle Group and SK Capital for a fraction of what it was once worth years ago.

Therapies 287
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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The brain perceives unexpected pain more strongly

Science Daily: Pharmacology News

Researchers used visual threat manipulation in the virtual reality environment and thermal stimulation to investigate how the brain perceives pain. They found that the brain perceives pain more strongly when the perceived pain is out of alignment with reality. In particular, pain was amplified when unexpected events occurred.

Research 308

More Trending

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Breathing and vision may be linked

Science Daily: Pharmacology News

Researchers have discovered a fundamental mechanism that affects the size of the pupil, namely our breathing. The study shows that the pupil is smallest during inhalation and largest during exhalation -- something that could affect our vision.

Research 300
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Rewards of Tight Blood Pressure Control Outweigh Risks, Trial Finds

Drugs.com

FRIDAY, Feb. 21, 2025 -- The health benefits of aggressive blood pressure control outweigh the potential risks for seniors, according to the latest results from a major clinical trial.About 85% of seniors treated to a target blood pressure of 120.

Trials 284
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Viking skulls reveal severe morbidity

Science Daily: Pharmacology News

Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more. This is shown in a study in which Viking skulls were examined using modern X-ray techniques.

Disease 296
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Ozempic, Wegovy shortage resolved; Pfizer CEO is PhRMA’s new chair

BioPharma Drive: Drug Pricing

The FDA determined that Novo Nordisk’s obesity and diabetes drugs are no longer in short supply. Elsewhere, Concentra made a competing bid for Acelyrin and Intra-Cellular sales rose.

FDA 264
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Dangerous Blood Clot Sidelines NBA Star Victor Wembanyama for the Season

Drugs.com

FRIDAY, Feb. 21, 2025 -- One of the NBA's most exciting rising stars will spend the rest of the 2024-2025 season on the bench. Victor Wembanyama, the San Antonio Spurs' 7-foot 3-inch phenom, was sidelined after doctors discovered a dangerous blood.

Doctors 246
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New microscope can image, at once, the full 3D orientation and position of molecules in cells

Science Daily: Pharmacology News

A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized fluorescence technology, a valuable tool for measuring the orientation of molecules, with a dual-view light sheet microscope (diSPIM), which excels at imaging along the depth (axial) axis of a sample.

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Vaccine Shows Promise for Pancreatic Cancer, Study Finds

Drugs.com

FRIDAY, Feb. 21, 2025 -- Adding a personalized mRNA vaccine to standard treatment could offer new hope for pancreatic cancer patients, a small yet promising study from Memorial Sloan Kettering Cancer Center.The study followed 16 patients, including.

Vaccine 246
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Pfizer stops selling hemophilia gene therapy, citing weak demand

BioPharma Drive: Drug Pricing

Pfizer’s decision to halt further marketing of Beqvez is further sign of the sparse patient interest in gene therapies for the bleeding condition.

Therapies 195
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Water, Plain Milk Are the Healthiest Drinks for Kids

Drugs.com

FRIDAY, Feb. 21, 2025 -- Got milk? It turns out, plain cows milk, water and a bit of veggie juice are still the best drink choices for kids and teens.That's the consensus of experts who recently issued healthy beverage recommendations for kids and.

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Agentforce and Unstructured Data = Yes!

Perficient: Drug Development

Leveraging data that is ‘trapped’ within unstructured data files like PDFs is a powerful capability within Agentforce. With an Agentforce Data Library this ability to surface PDF content through an Agent is now available in a ‘No Code’ fashion to all Salesforce Admins. So what is our Agentforce unstructured data use case? Let’s say we have a variety of PDFs about the warranty coverage for vehicles.

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This Flu Season Is Worst In A Decade

Drugs.com

FRIDAY, Feb. 21, 2025 -- The current flu season is shaping up to be the worst in a decade.So far, there have been at least 29 million illnesses and 370,000 hospitalizations related to the flu -- the most since the 2015-2016 season, according to the.

Hospitals 236
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From Data Gaps to Revenue Gains: Harnessing the Power of Comprehensive Data to Drive GTN

Drug Channels

Today's guest post comes from Thomas Luby, Sr. Vice President, Business Development at PHIL. Thomas discusses the challenges brands face as they manage gross-to-net (GTN) performance while simultaneously enhancing patient access and adherence. He lists the key performance indicators that can help brands improve GTN. To learn more, watch PHILs free on-demand webinar: Four Patient Access Barriers to Address for High-Impact Programs.

Drugs 52
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Black Cancer Death Rate Declining, But Higher Risk Remains

Drugs.com

FRIDAY, Feb. 21, 2025 -- Cancer deaths among Black men and women in the U.S. have declined during the past decade in the United States, a new American Cancer Society (ACS) report says.The cancer death rate decreased 49% among Black men and 33%.

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Walking Exercises Improve Stroke Rehab

Drugs.com

FRIDAY, Feb. 21, 2025 -- Stroke patients leave the hospital with better prospects if theyre forced to hoof it more during recovery, a new study suggests.Adding a half-hour of progressive walking exercises to standard stroke rehab measurably i.

Hospitals 173
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OD Deaths Decline in U.S., Driven By Drop In Opioid Fatalities

Drugs.com

FRIDAY, Feb. 21, 2025 -- Americas opioid crisis is showing signs of subsiding, a new report from the U.S. Centers for Disease Control and Prevention (CDC) says.Drug overdose deaths (OD) decreased by 4% between 2022 and 2023, according to the CDCs.

Disease 162
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New York Sues Vape Companies for Marketing to Youth, Violating Flavor Ban

Drugs.com

FRIDAY, Feb. 21, 2025 -- New York Attorney General Letitia James filed a major lawsuit yesterday, accusing 13 e-cigarette companies of illegally selling flavored vapes and targeting young kids through deceptive marketing.The 192-page complaint.

Marketing 147
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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TV Violence Linked To Aggression In Teenage Boys

Drugs.com

FRIDAY, Feb. 21, 2025 (HealthDay news) -- Superhero slugfests and TV tough-guy shootouts might have long-term effects on a preschool boys behavior, a new study says.Boys exposed to violent media between ages 3 and 5 are more likely to develop a.

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