Wed.Oct 16, 2024

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Elevating Employee Experience (EX) in the Age of AI

Perficient: Drug Development

Addressing the Talent Shortage While fears of AI-driven job displacement dominate headlines, the real crisis looming is a $8.5 trillion talent shortage projected by 2030. Much like the famous ‘invisible gorilla’ experiment, where viewers focused on counting basketball passes miss a costumed figure walking through the scene, businesses risk overlooking a crucial element: the Employee Experience (EX).

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Wave sees RNA editing validation in early trial results

BioPharma Drive: Drug Pricing

The results provide the first clinical evidence of RNA editing, a burgeoning field that's drawn interest from biotechs and pharmaceutical companies alike.

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Men and women process pain differently, study finds

Science Daily: Pharmacology News

According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in women.

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More Kids Having Seizures After Swallowing Rx Painkillers, Diphenhydramine, Synthetic Pot

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- The number of U.S. children who suffer seizures after swallowing prescription medications or illicit drugs has doubled in recent years, a new study finds. Drug poisonings among kids resulting in seizures increased from.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Bacterial vaccine shows promise as cancer immunotherapy

Science Daily: Pharmacology News

Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.

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Most Older Americans Don't Trust AI-Generated Health Info, Survey Finds

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Most Americans 50 and older don’t place much trust in health advice generated by artificial intelligence, a new survey finds.About 74% of middle-aged and senior Americans would have very little to no trust in health info.

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Rising Pharmaceutical Costs: A Major Challenge for Managed Healthcare

Drug Patent Watch

One issue continues to loom large in healthcare: the skyrocketing costs of pharmaceuticals. This challenge has become a significant hurdle for managed healthcare organizations, patients, and policymakers alike.

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'Two for the price of one' Scientists discover new process to drive anti-viral immunity

Science Daily: Pharmacology News

Scientists have discovered a new process in our immune systems that leads to the production of an important family of anti-viral proteins called interferons. They hope the discovery will now lead to new, effective therapies for people with some autoimmune and infectious diseases.Researchers have found that a natural metabolite called Itaconate can stimulate immune cells to make interferons by blocking an enzyme called SDH.

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Analyzing the impact of biosimilars on biologic drug development pipelines

Drug Patent Watch

Biosimilars, which are biologic drugs that are highly similar to an already approved biologic drug, are transforming the pharmaceutical industry. As patents for original biologic drugs expire, biosimilars are becoming increasingly important, offering more affordable treatment options for patients and healthcare systems.

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Breakthrough technology leads to life-saving treatment for deadly skin reaction

Science Daily: Pharmacology News

A global team of researchers has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis. This rare but often fatal reaction to common medications causes widespread detachment of the skin. Using innovative spatial proteomics -- one of the most advanced molecular biology tools -- the team identified the inflammatory JAK/STAT pathway as the main driver of disease.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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FDA puts Novavax flu vaccine trials on hold

BioPharma Drive: Drug Pricing

The hold, which was made in response to a serious adverse event report, could impact the company’s plans to start a Phase 3 trial of a combination shot for COVID-19 and influenza.

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One in three plants call islands home: Many at risk

Science Daily: Pharmacology News

From Tasmania to Madagascar to New Guinea, islands make up just over five per cent of Earth's land yet are home to 31 per cent of the world's plant species. A new study shows that of all plants classified as threatened worldwide, more than half are unique to islands, facing risks from habitat loss, climate warming and invasive species.

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GSK claims Moderna infringed mRNA vaccine patents

BioPharma Drive: Drug Pricing

The pharma’s lawsuit focuses on scientific work that helped clear the path for creating mRNA vaccines to fight the COVID-19 pandemic.

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Nitrogen pollution and rising carbon dioxide: A joint threat to grassland biodiversity?

Science Daily: Pharmacology News

An ecologically realistic 24-year field study of grasslands showed that elevated levels of carbon dioxide nearly tripled species losses attributed to nitrogen pollution.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Just Standing More Probably Won't Help Your Heart

Drugs.com

THURSDAY, Oct. 17, 2024 -- Got yourself a standing desk because you know sitting is unhealthy? It might be the wrong move, new research suggests. The study of over 83,000 British adults who wore special movement monitors on their wrists found no.

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The origin of most meteorites finally revealed

Science Daily: Pharmacology News

An international team has successfully demonstrated that 70% of all known meteorite falls originate from just three young asteroid families. These families were produced by three recent collisions that occurred in the main asteroid belt 5.8, 7.5, and about 40 million years ago. The team also revealed the sources of other types of meteorites; with this research, the origin of more than 90% of meteorites has now been identified.

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Skinny-Label Lives to See Another Day

FDA Law Blog: Biosimilars

By Sara W. Koblitz — Further talks of the Skinny Label’s demise may be premature, as demonstrated by a new decision from the District Court for the District of Columbia upholding FDA’s interpretation of the “same labeling” provisions of the Hatch-Waxman Amendments. That is not to say that concerns about the induced infringement theory at issue in GSK v.

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It's twins! Mystery of famed brown dwarf solved

Science Daily: Pharmacology News

An international team of astronomers has figured out that a famous brown dwarf is actually a pair of tight-knit brown dwarfs, weighing about 38 and 34 times the mass of Jupiter, that whip around each other every 12 days.

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Kidney Transplants Safe When Donor, Recipient Both HIV-Positive

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- People living with HIV who need a kidney can rest assured that outcomes are similar whether their kidney donor was also HIV-positive or not, a new study finds.One- and three-year survival was the same, regardless of the.

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Are nearby planets sending radio signals to each other?

Science Daily: Pharmacology News

Researchers have developed a new method using the Allen Telescope Array to search for interplanetary radio communication in the TRAPPIST-1 star system.

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New Combo Drug Therapy Halves Death Risk From Advanced Hodgkin Lymphoma

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Jenna Cottrell is a young sports reporter working for a TV station in the Rochester, N.Y., area. She's also a survivor of advanced Hodgkin lymphoma, who first got diagnosed at the age of 25 back in 2017.After 12 rounds.

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Human skin map gives 'recipe' to build skin and could help prevent scarring

Science Daily: Pharmacology News

Prenatal human skin atlas and organoid will accelerate research into congenital diseases and lead to clinical applications for regenerative medicine.

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Kicking Off Sitecore Symposium 2024 as an MVP

Perficient: Drug Development

Sitecore Symposium 2024 is Underway! A conference like Sitecore Symposium is a great way to make a mini vacation out of your work travels. I arrived on Sunday and explored the city of Nashville. Did you know that Nashville is home to a full-scale replica of the Parthenon? It was built in 1897 as part of the Tennessee Centennial Exposition. Today, it’s the only remaining building from the exposition and has since been turned into a museum.

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Prescribed Safer Supply Models in Canada

Common Sense for Drug Policy Blog

Prescribed Safer Supply Models in Canada "Within Canada, there are various prescribed safer supply models each with the goal of reducing unregulated opioid overdose without requiring cessation of substances. While some programs offer non-opioid safer supply options including stimulants and benzodiazepines, the primary focus remains opioids. These programs range in medications offered, clinical setting, and witnessed or unwitnessed ingestion ( Health Canada, 2023b ; Ledlie, Garg, et al., 2024 ).

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When Complications Strike After Heart Surgery, Women More Likely to Die Than Men

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Women and men experience similar rates of dangerous complications after a major heart surgery.So why are women dying at higher rates than men when these complications strike?That's the main question raised by a new study.

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From Fibroblasts to Cancer-Attacking Cells: Insights from Recent Research on Natural Killer Cells Derived from Clinical Grade iPSCs

Reprocell

In the past quarter-century, induced pluripotent stem cells (iPSCs) have emerged as a game-changer in medical research, offering groundbreaking opportunities for studying diseases and developing cutting-edge cell therapies. Their remarkable ability to self-renew indefinitely and differentiate into any cell type makes research, but especially clinical grade iPSCs, a versatile tool for regenerative medicine projects.

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Serena Williams Has Large Benign Cyst Removed From Neck

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Retired tennis legend Serena Williams has had a cyst on her neck "the size of a grapefruit" surgically removed and is in recovery, she announced Wednesday on social media. In May, "I found this big mass on my neck,".

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Samantha Ziegel Drives Innovation and Growth Across Perficient

Perficient: Drug Development

Meet Samantha Ziegel, Solutions Architect, Salesforce With Perficient’s Growth for Everyone initiative, we’re enabling colleague career development while celebrating the individual and collective success of our people. As a strong leader in the Salesforce Business Unit (BU) Samantha Ziegel is paving the way for exponential growth in Perficient’s Salesforce Data Cloud and Einstein AI offerings in her role as a solutions architect.

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ERs See More Trauma Patients on Smog-Filled Days

Drugs.com

WEDNESDAY, Oct. 15, 2024 -- Accident victims tend to flood emergency rooms on days with heavy air pollution, a new study shows.The number of patients treated at ERs increase by 10% to 15% on days with increased particle pollution in the air.

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Women in STEM with Cristina de Min

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? I’ve always been drawn to the early stages of scientific discovery, where hypotheses are formed and developed into something tangible that can benefit patients. Being involved in these formative stages allows you to not only understand the challenges ahead but also shape the science to ensure it addresses patient needs.

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Planes' Air Ventilation Can't Spread Nut Allergens to Passengers: Study

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Folks with peanut allergies don’t have to worry that someone might be munching on the nuts during an airline flight, researchers report.It turns out there’s no evidence to the commonly held belief that nut allergens can b.

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Novocure wins FDA approval for electric field device in lung cancer

BioPharma Drive: Drug Pricing

Alongside immunotherapy or chemo, the wearable device helped patients live longer in a trial, though the results are somewhat controversial.

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Obesity Could Cause 40% of Hormone-Positive Breast Cancers in Older Women

Drugs.com

WEDNESDAY, Oct. 16, 2024 -- Obesity is a more powerful driver of breast cancer than previously thought, a new study suggests.About 40% of hormone-positive breast cancers in postmenopausal women might be linked to excess body fat, researchers.

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ProductLife Group (PLG) Acquires Halloran

DS in Pharmatics

ProductLife Group (PLG), a trusted global leader in regulatory, scientific, compliance, and digital transformation consulting services for the life sciences, today announced the acquisition of Halloran Consulting Group, a life science consulting firm that provides strategic regulatory, quality, clinical, and organizational support in the pharmaceutical, biotechnology, and medical device sectors in the United States, further positioning PLG as a leading global provider of comprehensive healthcare