Tue.Aug 06, 2024

article thumbnail

Smallest arm bone in human fossil record sheds light on the dawn of Homo floresiensis

Science Daily: Pharmacology News

A new study reports the discovery of extremely rare early human fossils from the Indonesian island of Flores, including an astonishingly small adult limb bone. Dated to about 700,000 years old, the new findings shed light on the evolution of Homo floresiensis, the so-called 'Hobbits' of Flores whose remains were uncovered in 2003 at Liang Bua cave in the island's west.

141
141
article thumbnail

Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

BioPharma Drive: Drug Pricing

Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.

Licensing 133
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Exploring the potential of ADCs beyond oncology

Drug Target Review

What are the main therapeutic areas beyond oncology where ADCs show potential? A number of areas represent significant opportunities for Antibody Drug Conjugates (ADCs) beyond oncology, leveraging their ability to deliver therapeutic agents specifically to diseased cells or tissues while minimising off-target effects. The development of ADCs in these areas is ongoing, with several preclinical and clinical studies exploring their potential.

Therapies 118
article thumbnail

Biotech Red Queen launches with $55M to build versatile antivirals

BioPharma Drive: Drug Pricing

The funding from Apple Tree Partners will help the startup advance an antiviral drug pipeline that includes a COVID treatment nearing mid-stage testing.

Treatment 133
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Soft gold enables connections between nerves and electronics

Science Daily: Pharmacology News

Gold does not readily lend itself to being turned into long, thin threads. But researchers have now managed to create gold nanowires and develop soft electrodes that can be connected to the nervous system. The electrodes are soft as nerves, stretchable and electrically conductive, and are projected to last for a long time in the body.

Research 122
article thumbnail

When Your Knee Cartilage Wears Out, a 'Biomaterial' Might Help Replace It

Drugs.com

TUESDAY, Aug. 6, 2024 -- A newly developed biomaterial might be able to treat crippling arthritis by prompting the growth of new cartilage, a new animal study suggests.The bioactive material looks like rubbery goo, but it’s actually a complex b.

105
105

More Trending

article thumbnail

Is It Really Pneumonia? Study Casts Doubt on Hospital Diagnoses

Drugs.com

TUESDAY, Aug. 6, 2024 -- Hospitals could be frequently misdiagnosing pneumonia, causing patients to receive the wrong treatments and potentially become deathly ill, a new study finds.More than half the time, a pneumonia diagnosis will change.

Hospitals 105
article thumbnail

Biotech entrepreneur Arie Belldegrun launches new ‘science-first’ credit firm

BioPharma Drive: Drug Pricing

Symbiotic Capital, which has $600 million in committed capital, aims to make credit a more accessible tool for life sciences companies.

Science 117
article thumbnail

Study Shows How Fruits, Veggies Lower Blood Pressure, Heart Risks

Drugs.com

TUESDAY, Aug. 6, 2024 -- Eating more fruits and veggies can lower blood pressure and improve heart health by reducing acid levels in the body, a new clinical trial finds.People who added two to four cups of fruits and vegetables to their daily diet.

article thumbnail

Carvings at ancient monument may be world's oldest calendars

Science Daily: Pharmacology News

Markings on a stone pillar at a 12,000 year-old archaeological site in Turkey likely represent the world's oldest solar calendar, created as a memorial to a devastating comet strike, experts suggest.

104
104
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Marriage, Gender, Education, Race All Influence How Long You'll Live

Drugs.com

TUESDAY, Aug. 6, 2024 -- A person’s lifespan appears to be linked to four specific social factors – marriage, gender, education and race.The interplay between those four factors helps explain differences in lifespan between Americans, researchers re.

article thumbnail

Leveraging Automation to Streamline Clinical Data Management

Quanticate

The clinical trials industry is changing rapidly to move with today's technological advancements and at the front of this exciting movement is the adoption of AI (Artificial Intelligence) and ML (Machine Learning). Our industry has successfully incorporated both innovations to help push the boundaries of medical research and increase its effectiveness and efficiency through using these tools to help streamline and automate critical processes, which previously would have taken far longer to compl

article thumbnail

4 Tips to Keeping Your Gut Healthy and Free of IBD

Drugs.com

TUESDAY, Aug. 6, 2024 -- Almost 2.4 million Americans are thought to suffer from the pain and disability of inflammatory bowel disorder (IBD), a type of autoimmune illness that includes ulcerative colitis and Crohn's disease.You can avoid adding to.

98
article thumbnail

Merken Biotech Adopts CDD Vault for Advanced Drug Discovery Services

Collaborative Drug

Santiago, Chile – August 6, 2024—Merken Biotech, a leading research service company in biotechnology, proudly announces the adoption of CDD Vault, a premier informatics platform by Collaborative Drug Discovery (CDD). This strategic move will enhance Merken Biotech’s service capabilities, streamlining data management and accelerating drug discovery processes for its clients.

Drugs 90
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

U.S. Spends $43 Billion Annually on Cancer Screening

Drugs.com

TUESDAY, Aug. 6, 2024 -- Screening for cancer saves lives, but a new report shows it comes with a hefty price tag: The United States spends at least $43 billion annually on tests that check for five major cancers.Published Monday in the Annals of.

98
article thumbnail

Farmworker Appreciation Day 2024 – Celebrate the workers who bring us our daily bread (and everything else on our plate)

NIOSH Science Blog: Drugs

Few jobs are as essential as the ones that help to produce the food we eat, the clothes we wear, and many other products which get us through the day. From our morning coffee to a midnight snack, we benefit from the labor of farmworkers. The U.S employed approximately 2.6 million farmworkers in 2022 and contributed over $203 billion to the U.S. economy in 2023.

article thumbnail

How Wildfire Smoke Could Be Harming Surgical Patients

Drugs.com

TUESDAY, Aug. 6, 2024 -- Wildfire smoke could interfere with the safety of surgeries, a new study warns.Inhaling the smoke could complicate the effects of anesthesia on surgical patients, and it also might hamper their recovery, researchers.

article thumbnail

BioMarin pares Roctavian spending as it narrows sales focus

BioPharma Drive: Drug Pricing

The company plans to limit sales of the hemophilia gene therapy to the U.S., Italy and Germany, while ending most clinical development work.

article thumbnail

Number of Uninsured Americans Rose to 8.2% in 2024

Drugs.com

TUESDAY, Aug. 6, 2024 -- Following several years of record low rates of uninsured Americans, a new survey finds more folks are once again without health insurance.More than 8% of Americans did not have health coverage during the first few months of.

97
article thumbnail

RSV vaccine makers remain optimistic about market despite CDC guidance

BioPharma Drive: Drug Pricing

An advisory committee’s age group recommendations could curtail wider use for now, but executives at GSK, Pfizer and Moderna still see plenty of upside.

article thumbnail

Too Much Fun? Fireworks Displays Quickly Harm Air Quality

Drugs.com

TUESDAY, Aug. 6, 2024 -- Fireworks displays can cause worse air quality than wildfire smoke, a new study reveals.About 60,000 firework shells exploded over Manhattan’s East River as part of Macy’s Fourth of July show in 2023, researchers said.The co.

article thumbnail

New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

Drugs 52
article thumbnail

Fear of Falls, Injuries Can Plague Motorized Wheelchair Users

Drugs.com

TUESDAY, August 6, 2024 (HealthDay News) — When people who use wheelchairs or motorized scooters get hurt in a fall, fear that it will happen again may keep them on the sidelines of life, a new study warns. Falls may cause minor bruises and.

52
article thumbnail

Follow the 340B Prescription Dollar: How PBMs Profit from 340B Contract Pharmacies (Video)

Drug Channels

In my recent The 340B Drug Pricing Program: Trends, Controversies, and Outlook video webinar, I provided an update on the economics of the 340B program, reviewed the multiple controversies surrounding the program’s operations, discussed state and federal legislation, and analyzed how the Inflation Reduction Act of 2022 (IRA) will alter the 340B market.

article thumbnail

Fewer U.S. Teen Girls Are Reporting 'Persistent Sadness'

Drugs.com

TUESDAY, Aug. 6, 2024 -- There's a hint of good news for parents concerned about teen mental health: After 57% of U.S. teen girls surveyed in 2021 said they felt "persistent sadness," that number declined somewhat by 2023, to 53%, new government.

article thumbnail

Embracing Every Pathway with #NoWrongPath

Reprocell

As the results season looms over, it’s natural for many young people to feel a wave of anxiety and uncertainty. But we’re here to tell you that exam results are just one chapter in your story, not the entire book. This sentiment is powerfully echoed in the #NoWrongPath social media movement initiated by Developing the Young Workforce under Skills Development Scotland.

52
article thumbnail

Filmmaker David Lynch Has Emphysema

Drugs.com

TUESDAY, Aug. 6, 2024 -- David Lynch, who transformed television and film with series such as "Twin Peaks" and movies like "Blue Velvet" and "Mulholland Drive," announced Monday that he is battling the lung disease emphysema.Lynch, 78 and a former.

Disease 52
article thumbnail

Licensing Agreements in the Pharmaceutical Sector: A Comprehensive Guide

Drug Patent Watch

1. Introduction to Pharmaceutical Licensing In the fast-paced world of pharmaceuticals, innovation is the lifeblood that keeps the industry pumping.

article thumbnail

Hidden Thyroid Issues in Pregnancy Could Mean Thyroid Trouble Later

Drugs.com

TUESDAY, Aug 6, 2024 -- Women who develop subclinical thyroid issues during pregnancy, meaning symptoms haven't surfaced, could face real thyroid trouble within five years, a new study finds.Pregnant women who were diagnosed with subclinical.

52
article thumbnail

How to Enhance Generic Drug Development Efficiency

Drug Patent Watch

Enhancing the efficiency of generic drug development is crucial for improving patient access to affordable medications.

article thumbnail

FDA Drug Labeling Requirements & Regulations: What’s in Your Label?

thought leadership

Why Does Pharmaceutical Product Labeling Matter? Do you know what’s in your product’s labeling and what it is saying about your product? More importantly, do you know why that matters?

article thumbnail

Future drug patent expirations by year

Drug Patent Watch

Pharmaceutical drug patents enable branded drug companies to prevent market entry by competitors until the patents expire.

Drugs 52
article thumbnail

Understanding Microservices Architecture: Benefits and Challenges Explained

Perficient: Drug Development

Understanding Microservices Architecture: Benefits and Challenges Explained Microservices architecture is a transformative approach in backend development that has gained immense popularity in recent years. To fully grasp the advantages of microservices, it is essential first to understand monolithic architecture, as microservices emerged primarily to address its limitations.