Tue.Aug 06, 2024

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Smallest arm bone in human fossil record sheds light on the dawn of Homo floresiensis

Science Daily: Pharmacology News

A new study reports the discovery of extremely rare early human fossils from the Indonesian island of Flores, including an astonishingly small adult limb bone. Dated to about 700,000 years old, the new findings shed light on the evolution of Homo floresiensis, the so-called 'Hobbits' of Flores whose remains were uncovered in 2003 at Liang Bua cave in the island's west.

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Biotech Red Queen launches with $55M to build versatile antivirals

BioPharma Drive: Drug Pricing

The funding from Apple Tree Partners will help the startup advance an antiviral drug pipeline that includes a COVID treatment nearing mid-stage testing.

Treatment 131
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Eating more fruits and vegetables to reduce dietary acid lowers blood pressure and improves kidney and heart health in patients with hypertension

Science Daily: Pharmacology News

Doctors recommend making fruits and vegetables a foundational part of the treatment of patients with hypertension. Diets high in fruits and vegetables are found to lower blood pressure, reduce cardiovascular risk, and improve kidney health due to their base-producing effects. A new study details the findings from a five-year interventional randomized control trial.

Doctors 131
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Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

BioPharma Drive: Drug Pricing

Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.

Licensing 131
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Soft gold enables connections between nerves and electronics

Science Daily: Pharmacology News

Gold does not readily lend itself to being turned into long, thin threads. But researchers have now managed to create gold nanowires and develop soft electrodes that can be connected to the nervous system. The electrodes are soft as nerves, stretchable and electrically conductive, and are projected to last for a long time in the body.

Research 125

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Biotech entrepreneur Arie Belldegrun launches new ‘science-first’ credit firm

BioPharma Drive: Drug Pricing

Symbiotic Capital, which has $600 million in committed capital, aims to make credit a more accessible tool for life sciences companies.

Science 114
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Carvings at ancient monument may be world's oldest calendars

Science Daily: Pharmacology News

Markings on a stone pillar at a 12,000 year-old archaeological site in Turkey likely represent the world's oldest solar calendar, created as a memorial to a devastating comet strike, experts suggest.

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When Your Knee Cartilage Wears Out, a 'Biomaterial' Might Help Replace It

Drugs.com

TUESDAY, Aug. 6, 2024 -- A newly developed biomaterial might be able to treat crippling arthritis by prompting the growth of new cartilage, a new animal study suggests.The bioactive material looks like rubbery goo, but it’s actually a complex b.

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Leveraging Automation to Streamline Clinical Data Management

Quanticate

The clinical trials industry is changing rapidly to move with today's technological advancements and at the front of this exciting movement is the adoption of AI (Artificial Intelligence) and ML (Machine Learning). Our industry has successfully incorporated both innovations to help push the boundaries of medical research and increase its effectiveness and efficiency through using these tools to help streamline and automate critical processes, which previously would have taken far longer to compl

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Study Shows How Fruits, Veggies Lower Blood Pressure, Heart Risks

Drugs.com

TUESDAY, Aug. 6, 2024 -- Eating more fruits and veggies can lower blood pressure and improve heart health by reducing acid levels in the body, a new clinical trial finds.People who added two to four cups of fruits and vegetables to their daily diet.

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Understanding Microservices Architecture: Benefits and Challenges Explained

Perficient: Drug Development

Understanding Microservices Architecture: Benefits and Challenges Explained Microservices architecture is a transformative approach in backend development that has gained immense popularity in recent years. To fully grasp the advantages of microservices, it is essential first to understand monolithic architecture, as microservices emerged primarily to address its limitations.

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Is It Really Pneumonia? Study Casts Doubt on Hospital Diagnoses

Drugs.com

TUESDAY, Aug. 6, 2024 -- Hospitals could be frequently misdiagnosing pneumonia, causing patients to receive the wrong treatments and potentially become deathly ill, a new study finds.More than half the time, a pneumonia diagnosis will change.

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Merken Biotech Adopts CDD Vault for Advanced Drug Discovery Services

Collaborative Drug

Santiago, Chile – August 6, 2024—Merken Biotech, a leading research service company in biotechnology, proudly announces the adoption of CDD Vault, a premier informatics platform by Collaborative Drug Discovery (CDD). This strategic move will enhance Merken Biotech’s service capabilities, streamlining data management and accelerating drug discovery processes for its clients.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Marriage, Gender, Education, Race All Influence How Long You'll Live

Drugs.com

TUESDAY, Aug. 6, 2024 -- A person’s lifespan appears to be linked to four specific social factors – marriage, gender, education and race.The interplay between those four factors helps explain differences in lifespan between Americans, researchers re.

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Follow the 340B Prescription Dollar: How PBMs Profit from 340B Contract Pharmacies (Video)

Drug Channels

In my recent The 340B Drug Pricing Program: Trends, Controversies, and Outlook video webinar, I provided an update on the economics of the 340B program, reviewed the multiple controversies surrounding the program’s operations, discussed state and federal legislation, and analyzed how the Inflation Reduction Act of 2022 (IRA) will alter the 340B market.

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4 Tips to Keeping Your Gut Healthy and Free of IBD

Drugs.com

TUESDAY, Aug. 6, 2024 -- Almost 2.4 million Americans are thought to suffer from the pain and disability of inflammatory bowel disorder (IBD), a type of autoimmune illness that includes ulcerative colitis and Crohn's disease.You can avoid adding to.

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Farmworker Appreciation Day 2024 – Celebrate the workers who bring us our daily bread (and everything else on our plate)

NIOSH Science Blog: Drugs

Few jobs are as essential as the ones that help to produce the food we eat, the clothes we wear, and many other products which get us through the day. From our morning coffee to a midnight snack, we benefit from the labor of farmworkers. The U.S employed approximately 2.6 million farmworkers in 2022 and contributed over $203 billion to the U.S. economy in 2023.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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U.S. Spends $43 Billion Annually on Cancer Screening

Drugs.com

TUESDAY, Aug. 6, 2024 -- Screening for cancer saves lives, but a new report shows it comes with a hefty price tag: The United States spends at least $43 billion annually on tests that check for five major cancers.Published Monday in the Annals of.

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RSV vaccine makers remain optimistic about market despite CDC guidance

BioPharma Drive: Drug Pricing

An advisory committee’s age group recommendations could curtail wider use for now, but executives at GSK, Pfizer and Moderna still see plenty of upside.

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How Wildfire Smoke Could Be Harming Surgical Patients

Drugs.com

TUESDAY, Aug. 6, 2024 -- Wildfire smoke could interfere with the safety of surgeries, a new study warns.Inhaling the smoke could complicate the effects of anesthesia on surgical patients, and it also might hamper their recovery, researchers.

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BioMarin pares Roctavian spending as it narrows sales focus

BioPharma Drive: Drug Pricing

The company plans to limit sales of the hemophilia gene therapy to the U.S., Italy and Germany, while ending most clinical development work.

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Number of Uninsured Americans Rose to 8.2% in 2024

Drugs.com

TUESDAY, Aug. 6, 2024 -- Following several years of record low rates of uninsured Americans, a new survey finds more folks are once again without health insurance.More than 8% of Americans did not have health coverage during the first few months of.

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Future drug patent expirations by year

Drug Patent Watch

Pharmaceutical drug patents enable branded drug companies to prevent market entry by competitors until the patents expire.

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Too Much Fun? Fireworks Displays Quickly Harm Air Quality

Drugs.com

TUESDAY, Aug. 6, 2024 -- Fireworks displays can cause worse air quality than wildfire smoke, a new study reveals.About 60,000 firework shells exploded over Manhattan’s East River as part of Macy’s Fourth of July show in 2023, researchers said.The co.

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New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

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Fear of Falls, Injuries Can Plague Motorized Wheelchair Users

Drugs.com

TUESDAY, August 6, 2024 (HealthDay News) — When people who use wheelchairs or motorized scooters get hurt in a fall, fear that it will happen again may keep them on the sidelines of life, a new study warns. Falls may cause minor bruises and.

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How to Enhance Generic Drug Development Efficiency

Drug Patent Watch

Enhancing the efficiency of generic drug development is crucial for improving patient access to affordable medications.