Sun.Apr 28, 2024

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Chemical Biology and Drug Design

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Discovery of a Tunable Heterocyclic Electrophile 4-Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines

Covalent Modifiers

Hong-Rae Kim, David P. Byun, Kalyani Thakur, Jennifer Ritchie, Yixin Xie, Ronald Holewinski, Kiall F. Suazo, Mckayla Stevens, Hope Liechty, Ravichandra Tagirasa, Yihang Jing, Thorkell Andresson, Steven M. Johnson, and Euna Yoo ACS Chemical Biology 2024 [link] Electrophilic small molecules with novel reactivity are powerful tools that enable activity-based protein profiling and covalent inhibitor discovery.

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Which pharmaceutical companies have the most gas dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most gas dosed drugs. For a different perspective, see the most popular dosage types.