Science Daily: Pharmacology News
FEBRUARY 21, 2024
Scientists introduce what they call 'simultaneous and heterogeneous multithreading' or SHMT. This system doubles computer processing speeds with existing hardware by simultaneously using graphics processing units (GPUs), hardware accelerators for artificial intelligence (AI) and machine learning (ML), or digital signal processing units to process information.
Chemical Biology and Drug Design
FEBRUARY 21, 2024
JNK3 serves as a neuronal kinase with the capacity for activation upon exposure to stress response like oxygen–glucose deprivation. Upon phosphorylation and activation, JNK3 relocates to the mitochondria, where it is thought to enhance the permeability of the mitochondrial outer membrane (MOMP). This heightened MOMP leads to the release of Cyt-c into the cytoplasm, forming a complex with apaf-1 that triggers enzyme activation.
BioPharma Drive: Drug Pricing
FEBRUARY 21, 2024
The full results spotlight cell therapy’s potential to treat lupus and other inflammatory conditions, but also the problems drug developers must solve first.
Broad Institute
FEBRUARY 21, 2024
#WhyIScience Q&A: A software engineer develops computational tools for psychiatric and brain research By Claire Hendershot February 21, 2024 Breadcrumb Home #WhyIScience Q&A: A software engineer develops computational tools for psychiatric and brain research Khalid Shakir talks about his work analyzing large single-cell datasets, his excitement around AI, and the importance of mentorship and community in science.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- A popular asthma inhaler was discontinued on Jan. 1, and the business move has left families scrambling to find a replacement for their kids.Flovent was one of the most commonly prescribed drugs for childhood asthma, but.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
The supermassive black hole in the center of the Milky Way is spinning so quickly it is warping the spacetime surrounding it into a shape that can look like a football, according to a new study. That football shape suggests the black hole is spinning at a substantial speed, which researchers estimated to be about 60% of its potential limit.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
FEBRUARY 21, 2024
To access previous blog, click this link: – Tutorial 02 – Spring Cloud – Netflix Eureka Server Publish Microservice to Eureka Server Every Microservice must be published/ registered with Eureka Server (R&D Server) by becoming Eureka Client We must create a microservice using Spring Rest Controller to offer support. The @EnableEurekaClient annotation is not required anymore from spring 3.x onwards.
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- In a ruling that could drastically limit future infertility care, the Alabama Supreme Court has ruled that frozen embryos can be considered children under state law.In the decision, judges turned to what it called.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
The iconic baleen whales, such as the blue, gray and humpback whale, depend on sound for communication in the vast marine environment where they live. Now researchers have for the first time found that baleen whales evolved novel structures in their larynx to make their vast array of underwater songs.
BioPharma Drive: Drug Pricing
FEBRUARY 21, 2024
One expert views Amtagvi’s approval as a catalyst for further investment in TIL therapies, akin to how Kymriah’s 2017 clearance buoyed CAR-T treatment.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
Neanderthals created stone tools held together by a multi-component adhesive, a team of scientists has discovered. Its findings, which are the earliest evidence of a complex adhesive in Europe, suggest these predecessors to modern humans had a higher level of cognition and cultural development than previously thought.
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- Mercury levels in tuna haven’t changed since 1971, despite efforts to reduce emissions of the toxic metal into the environment, researchers report.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
A global team of researchers has invented recyclable 'water batteries' that won't catch fire or explode. The team use water to replace organic electrolytes -- which enable the flow of electric current between the positive and negative terminals -- meaning their batteries can't start a fire or blow up -- unlike their lithium-ion counterparts.
Perficient: Drug Development
FEBRUARY 21, 2024
We have already seen the experience editor part in the Extending General Link for Experience Editor article in detail. Hence, in this article, we will explore how we can extend the general link for experience editor mode with an alternate code approach in Sitecore 10.2.0 to resolve the higher environment and performance issues that occurred after implementing the additional security certificates.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- If you're female and you lose bladder control upon exertion -- sneezing, coughing, laughing, lifting something heavy -- you may have stress urinary incontinence.As many women know, the condition is no joke and it may.
Drug Channels
FEBRUARY 21, 2024
Like many of you, I have believed that the Inflation Reduction Act of 2022 (IRA) will encourage Medicare Part D plans to adopt low-list-price products over their high-list/high-rebate counterparts, thereby popping the gross-to-net bubble. Actually, maybe not. Below, I explain why the IRA will encourage Part D plans to prefer high-list, high-rebate specialty drugs , even as the government and manufacturers will prefer a low-list-price version.
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- If all cars and trucks sold in America were "zero emission" by 2040 and the country's electric grid was also powered by clean energy, nearly 2.8 million child asthma attacks would be prevented annually, a new report.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
Researchers evaluated the prevalence, concentration and tissue distribution of essential and non-essential trace elements, including heavy metal toxicants in tissue (blubber, kidney, liver, skeletal muscle, skin) and fecal samples collected from 90 whales and dolphins stranded in Georgia and Florida from 2007 to 2021.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- People with diabetes have to spend a ton of money to stay healthy, a new study reports.Total and out-of-pocket costs for diabetics run hundreds to thousands of dollars more than regular medical expenses for people.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
Membranes of vertically aligned carbon nanotubes (VaCNT) can be used to clean or desalinate water at high flow rate and low pressure. Recently, researchers carried out steroid hormone adsorption experiments to study the interplay of forces in the small pores. They found that VaCNT of specific pore geometry and pore surface structure are suited for use as highly selective membranes.
SCIENMAG: Medicine & Health
FEBRUARY 21, 2024
Most chronic wound infections share one thing in common: the presence of biofilms, which are composed of many different microorganisms that congregate as a mass, usually on some type of surface such as a wound bed.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
Comparison of over 200 high-quality butterfly and moth genomes reveals key insights into their biology, evolution and diversification over the last 250 million years, as well as clues for conservation.
SCIENMAG: Medicine & Health
FEBRUARY 21, 2024
Body composition — often expressed as the amount of fat in relation to muscle — is one of the standard predictors of cardiac health. Now, new research from the University of California San Diego indicates more muscle doesn’t automatically mean lower risk of heart trouble.
Fierce BioTech
FEBRUARY 21, 2024
Cancer diagnosis often involves a multitude of tests after symptom onset, complicating treatment for tumors that are no longer localized.
SCIENMAG: Medicine & Health
FEBRUARY 21, 2024
Using intravascular imaging to guide stent implantation during percutaneous coronary intervention (PCI) in heart disease patients significantly improves survival and reduces adverse cardiovascular events compared to angiography-guided PCI alone, the most commonly used method.
Conversations in Drug Development Trends
FEBRUARY 21, 2024
During clinical development, new chemical entities (NCEs) require an absorption, metabolism, and excretion (AME) study. Also known as a human radiolabeled mass balanced study, the AME study aims to determine the overall metabolism and excretion pathways of the NCE, as well as to identify and quantify circulating metabolites relative to parent or total drug-related exposure.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes. Not good if the objective of the project was to harness the metabolism of living bacteria to produce electricity.
Drugs.com
FEBRUARY 21, 2024
WEDNESDAY, Feb. 21, 2024 -- A ban on menthol cigarettes would likely lead to a meaningful reduction in smoking rates, a new review argues.Almost a quarter of menthol smokers quit smoking altogether after menthol cigarettes were banned in their.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
Researchers have discovered that a mutation in the cellulose making machinery of E. coli bacteria allows them to cause severe disease in people -- 'good' bacteria make cellulose and 'bad' bacteria can't. The mutations stopped the E. coli making the cell-surface carbohydrate cellulose and this led to increased inflammation in the intestinal tract of the host, resulting in a breakdown of the intestinal barrier, so the bacteria could spread through the body.
SCIENMAG: Medicine & Health
FEBRUARY 21, 2024
LA JOLLA, CA—Scripps Research scientists have developed an antibody that can block the effects of lethal toxins in the venoms of a wide variety of snakes found throughout Africa, Asia and Australia.
Science Daily: Pharmacology News
FEBRUARY 21, 2024
A new technique can help researchers who use Bayesian inference achieve more accurate results more quickly, without a lot of additional work.
SCIENMAG: Medicine & Health
FEBRUARY 21, 2024
Raised blood pressure has been the leading risk factor for death in Australia for the past three decades, according to a study published February 21, 2024, in the open-access journal PLOS ONE led by Alta Schutte and Xiaoyue Xu from The George Institute for Global Health and UNSW, Sydney, with colleagues across Australia.
BioPharma Drive: Drug Pricing
FEBRUARY 21, 2024
The biotech alleges that the agency is letting competitor Liquidia sidestep the rules by accepting an amendment to an application that’s involved in a patent dispute.
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