Thu.Mar 13, 2025

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MeiraGTx spins Parkinson’s, obesity gene therapies into AI startup

BioPharma Drive: Drug Pricing

The joint venture with generative AI firm Hologen hands MeiraGTx $200 million up front as well as other financial perks — a “transformative” deal, according to the company’s CEO.

Therapies 296
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US bird populations continue alarming decline

Science Daily: Pharmacology News

The 2025 U. S. State of the Birds Report, produced by a coalition of leading science and conservation organizations, reveals continued widespread declines in American bird populations across all mainland and marine habitats, with 229 species requiring urgent conservation action.

Science 274
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Small Number of Acne Products Recalled for Problematic Levels of Benzene

Drugs.com

THURSDAY, March 13, 2025 -- After new U.S. Food and Drug Administration testing of acne products containing benzoyl peroxide, the agency determined that a small number of products should be recalled for possible benzene contamination, the FDA.

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Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells

Chemical Biology and Drug Design

Design and synthesis of pyrrole-tethered bisbenzoxazole (PTB) derivatives reveal potent anticancer activity against MCF-7 breast cancer cells. Compounds B8 , B14 , and B18 exhibit ~20-fold lower IC 50 values than tamoxifen, induce early-stage apoptosis, and arrest the cell cycle at the G1 phase via caspase-9 activation. These findings position PTB derivatives as promising candidates for targeted breast cancer therapy.

Therapies 100
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Mallinckrodt, Endo to combine in $7B deal

BioPharma Drive: Drug Pricing

The merger will give the combined entity the financial flexibility to pursue drug licensing deals and broaden its therapeutic focus, executives said on a conference call.

Licensing 246

More Trending

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Robert F. Kennedy Jr. Downplays Measles Vaccine as Cases Surge

Drugs.com

THURSDAY, March 13, 2025 -- A growing measles outbreak has led to 222 reported cases across Texas, New Mexico and Oklahoma in 2025, with health officials urging more people to get vaccinated. During an interview with Fox News, U.S. Health and Human.

Vaccine 222
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Most current AI struggles to read clocks and calendars

Science Daily: Pharmacology News

Some of the world's most advanced AI systems struggle to tell the time and work out dates on calendars, a study suggests.

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Weed Use During Pregnancy Triples Risk Of Behavioral Problems In Kids

Drugs.com

THURSDAY, March 13, 2025 -- Some women turn to weed during pregnancy to help deal with common issues like nausea, sleep problem and stress.Unfortunately, they could be endangering their unborn childs future behavior, a new study says.Women who use.

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Does exercise really extend life? Finnish twin study offers new insights

Science Daily: Pharmacology News

Physical activity is seen as a way to extend the human lifespan, but twin studies found the benefits of physical activity for longevity may not be as straightforward as has been previously thought.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Girl Scouts Say Cookies Are Safe Despite Lawsuit Claiming They Contain Heavy Metals

Drugs.com

THURSDAY, March 13, 2025 -- Two groups focused on food safety and environmental toxins have sued Girl Scouts of America, claiming that their perennially popular cookies are tainted with pesticides and heavy metals. GMO Science and Moms Across.

Science 191
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Dozens of 3-toed dinosaurs leave their mark in Australia

Science Daily: Pharmacology News

A researcher has confirmed a boulder at a regional school contains one of the highest concentrations of dinosaur footprints per square meter ever documented in Australia.

Research 214
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Concussion Damage Lingers In Athletes' Brains Up To A Year

Drugs.com

THURSDAY, March 13, 2025 -- Concussion damage could linger in an athletes brain for at least a year, long after theyve rejoined their sport, a new study says.Concussed college athletes had brain changes that remained visible in brain scans up to a.

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Engineers turn skin cells directly into neurons for cell therapy

Science Daily: Pharmacology News

Researchers devised a process to convert a skin cell directly into a neuron, eliminating the need to generate induced pluripotent stem cells. Such neurons could be used to treat spinal cord injuries or diseases such as ALS.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Federal Addiction And Mental Health Agency Faces Major Staff Cuts

Drugs.com

THURSDAY, March 13, 2025 -- A key federal agency responsible for addiction and mental health services is facing deep staff cuts. The Substance Abuse and Mental Health Services Administration (SAMHSA), which has a $7.2 billion budget, oversees vital.

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Spinning, twisted light could power next-generation electronics

Science Daily: Pharmacology News

Researchers have advanced a decades-old challenge in the field of organic semiconductors, opening new possibilities for the future of electronics. The researchers have created an organic semiconductor that forces electrons to move in a spiral pattern, which could improve the efficiency of OLED displays in television and smartphone screens, or power next-generation computing technologies such as spintronics and quantum computing.

Research 178
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Pandemic Set Kindergarteners Back Developmentally

Drugs.com

THURSDAY, March 13, 2025 -- The COVID-19 pandemic set kindergarteners development back in several ways, a new study says.Post-pandemic kindergarten students on average scored significantly lower in language and thinking skills, social competence, a.

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Study highlights noninvasive hearing aid

Science Daily: Pharmacology News

A study highlights a new approach in addressing conductive hearing loss. A team of scientists has designed a new type of hearing aid that not only improves hearing but also offers a safe, non-invasive alternative to implantable devices and corrective surgeries.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Turning Off TV Better For Heart Health Of Folks Predisposed To Diabetes

Drugs.com

THURSDAY, March 13, 2025 -- People with a higher genetic risk for type 2 diabetes also have a higher risk of heart attack, stroke and other heart-related diseases.But controlling that risk could be as simple as picking up a TV remote and hitting.

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New name for one of the world's rarest rhinoceroses

Science Daily: Pharmacology News

A recent study has reclassified the species commonly known as the Javan rhinoceros, proposing a more precise scientific name: Eurhinoceros sondaicus. The research highlights key differences in body structure and ecology that set this species apart from the Indian rhinoceros (Rhinoceros unicornis). Recognizing it as a separate genus not only improves scientific understanding but also has important implications for conservation efforts.

Research 227
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Red Wine Protects Against Cancer? Maybe Not

Drugs.com

THURSDAY, March 13, 2025 -- Red wine has been thought to potentially offer protection against cancer, given its high levels of the anti-inflammatory antioxidant resveratrol.But theres no clear evidence that red wine lessens cancer risk, a new e.

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Study Identifies 7 Genes Associated with Brain Aging and 13 Drugs that May Help Extend the Healthspan

PLOS: DNA Science

Consider two 70-year-olds. Cliff seems slightly confused and forgetful, and has difficulty following conversations and instructions. Roxanne is always alert and leads conversations, bringing up new topics and easily adding details to other’s ideas. They are the same age, yet far apart in cognition. Researchers call the difference between age in years and age in behavior and physical condition the brain age gap , or BAG.

Drugs 71
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OB/GYNs Walk Away From Anti-Abortion States

Drugs.com

THURSDAY, March 13, 2025 -- A brain drain is underway in states that banned or severely restricted abortion after the fall of Roe v Wade, a new study suggests.A significant decline in the number of practicing obstetricians/gynecologists has.

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ADI | Snap One and Perficient Win Coveo Relevance Accelerator Award

Perficient: Drug Development

Perficient is excited to announce weve won Coveos exclusive partner award for the third time since inception! The Accelerator Award commemorates a Coveo partner and customer that worked together and exhibited deep knowledge and technical expertise and clearly delivered value-driven business outcomes. A Coveo platinum partner with 100+ Coveo consultants globally, our award-winning work in collaboration with ADI | Snap One paved the way for increased conversions and purchases with fewer rules whil

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Navigating the AI revolution: a roadmap for pharma’s future

Drug Target Review

Planning the journey from data to deliverables The future of AI-enabled drug development benefits from the continued advancement of multimodality and clinical genomics, with a focus on integration, efficiency and personalisation to transform both care and R&D. These evolving technologies have enormous potential to overcome current limitations in the field.

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Navigating the New EU Health Technology Assessment Regulation (HTAR): Are You Ready?

thought leadership

The HTAR in the EU has come into force what Health Technology Developers (HTDs) need to know Getting your health technology product to the market is complex and usually consists of several steps that require strategic planning, evidence generation, and stakeholder engagement. Health technology developers (HTDs) that have clear goals set from the beginning, have conducted market research, and have a clear organizational and financial plan, are usually the winning party at market entry and produc

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Target Innovation & Novel Screening Technologies – Forum Round-Up

Elrig

Target Innovation & Novel Screening Technologies – Forum Round-Up In the rapidly evolving landscape of drug discovery, the identification and validation of novel therapeutic targets are pivotal to expanding the druggable genome and tackling unmet medical needs. ELRIGs German Forum, provided the stage for expert speakers to share novel research that is actively shaping the future of the field.

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Addressing supply chain challenges for biosimilar products

Drug Patent Watch

Navigating the Complex World of Biosimilar Supply Chains As the demand for biosimilars continues to grow, so do the challenges associated with their supply chains. From manufacturing and quality control to distribution and regulatory compliance, the stakes are high for pharmaceutical companies looking to bring these life-changing treatments to market.