Tue.Jul 23, 2024

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Study Finds Big Shift in Who's Using GLP-1 Meds Like Ozempic

Drugs.com

TUESDAY, July 23, 2024 -- The boom in using GLP-1 drugs like Ozempic to treat obesity has resulted in a bust regarding the drugs’ original purpose, which was to treat type 2 diabetes, a new study finds. New prescriptions for these drugs have d.

Drugs 119
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Butterflies accumulate enough static electricity to attract pollen without contact

Science Daily: Pharmacology News

Butterflies and moths collect so much static electricity whilst in flight, that pollen grains from flowers can be pulled by static electricity across air gaps of several millimeters or centimeters.

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Predicting Myriad Diseases From a Single Drop of Blood

Drugs.com

TUESDAY, July 23, 2024 -- A single drop of blood might be able to predict the onset of dozens of diseases, a new study claims.Analysis of the protein “signatures” in a droplet of blood can predict 67 diseases, including blood cancers, degenerative n.

Disease 111
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FDA Releases Draft Guidance on Essential Drug Delivery Outputs

FDA Law Blog: Biosimilars

By Adrienne R. Lenz, Principal Medical Device Regulation Expert — For several years, FDA has requested that sponsors of drug or biologic led combination products identify essential performance requirements (EPRs) related to the device constituent in their applications. EPRs were usually requested in the context of design controls, although 21 C.F.R. § 820.30 does not use this term.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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#WhyIScience Q&A: A mechanical engineer builds microscopes to give new spatial views of cells and tissues

Broad Institute

#WhyIScience Q&A: A mechanical engineer builds microscopes to give new spatial views of cells and tissues By Leah Eisenstadt July 23, 2024 Breadcrumb Home #WhyIScience Q&A: A mechanical engineer builds microscopes to give new spatial views of cells and tissues Lindsey Erion-Barner describes her efforts to develop and share innovative tools in the Spatial Technology Platform By Leah Eisenstadt July 23, 2024 Credit: Allison Colorado, Broad Communications Lindsey Erion-Barner develops and shares

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U.S. Injuries From Electric Bikes, Scooters Are Soaring

Drugs.com

TUESDAY, July 23, 2024 -- More and more Americans who use "micromobility" transport, such as electric bikes and e-scooters, are motoring their way straight into the ER, new data shows. In fact, the rate of e-bike injuries among Americans doubled.

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Another Study Ties Poor Sleep to Type 2 Diabetes

Drugs.com

TUESDAY, July 23, 2024 -- Consistently bad sleep is linked to a person’s risk of developing type 2 diabetes, a new study shows.Both too little and too much sleep is tied to diabetes risk, and swinging wildly between the two patterns of poor sleep r.

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3D-printed microstructure forest facilitates solar steam generator desalination

Science Daily: Pharmacology News

Faced with the world's impending freshwater scarcity, researchers turned to solar steam generators, which are emerging as a promising device for seawater desalination. The team sought design inspiration from trees and harnessed the potential of 3D printing. They present technology for producing efficient SSGs for desalination and introduces a novel method for printing functional nanocomposites for multi-jet fusion.

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Startup led by former J&J executives raises $165M for cancer, immune disease drugs

BioPharma Drive: Drug Pricing

Peter Lebowitz, who for years led J&J’s oncology R&D, is the CEO of the startup, called Third Arc Bio and launched by Omega Funds in 2022.

Disease 87
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Taco-shaped arthropod fossils gives new insights into the history of the first mandibulates

Science Daily: Pharmacology News

Palaeontologists are helping resolve the evolution and ecology of Odaraia, a taco-shaped marine animal that lived during the Cambrian period. Fossils reveal Odaraia had mandibles. Palaeontologists are finally able to place it as belonging to the mandibulates, ending its long enigmatic classification among the arthropods since it was first discovered in the Burgess Shale over 100 years ago and revealing more about early evolution and diversification.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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How Well Would Meds Work on a Mission to Mars?

Drugs.com

TUESDAY, July 23, 2024 -- How many drugs in your bathroom medicine cabinet have expired?Now imagine you have no way of refilling them, because you’re millions of miles from home.That’s the dilemma that will face astronauts on a Mars mission, a new s.

Drugs 69
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Hunter-gatherers kept an 'orderly home' in the earliest known British dwelling

Science Daily: Pharmacology News

Archaeological evidence from the world-famous Mesolithic site of Star Carr in North Yorkshire has shown that hunter-gatherers likely kept an orderly home by creating 'zones' for particular domestic activities.

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Merck claims late-stage study success for RSV antibody

BioPharma Drive: Drug Pricing

The drug, a rival to Sanofi and AstraZeneca’s fast-selling Beyfortus, met its main goals in a Phase 3 trial. But undisclosed study results leave its full potential unclear.

Trials 67
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Drawing water from dry air

Science Daily: Pharmacology News

A prototype device harvests drinking water from the atmosphere, even in arid places.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The MTA at Addgene

addgene Blog

If you’ve deposited or requested plasmids from Addgene, then you’ve been involved in the material transfer agreement (MTA) process. Even though this process is essential to sharing plasmids around the globe, it can be a bit of a mystery for those who aren’t familiar with it. If you’re curious about the hows and whys of the material transfer agreement, read on!

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Don’t Drown in Data – Clinical Research Data Management Can be Easy, with a Little REST

Crucial Data Solutions

It is not hyperbole to say that data is transforming clinical research at a breakneck pace. The critical need to. The post Don’t Drown in Data – Clinical Research Data Management Can be Easy, with a Little REST appeared first on Crucial Data Solutions.

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Beyond the Classroom: TKS Students Make Real-World Impact at BenchSci

BenchSci

This summer, we welcomed three high school students from The Knowledge Society (TKS) to the BenchSci team for an immersive internship experience. While we haven't historically had a formal internship program, we’ve had a long-standing partnership with TKS and have continued to be impressed with the exceptional young minds that participate in their program.

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City vs. Country vs. Suburbs: Who's Happier?

Drugs.com

TUESDAY, July 23, 2024 -- City dwellers are less likely to be healthy, happy and well-off than people living outside urban areas, a new study reports.Instead, there’s a suburban “Goldilocks zone” between cities and rural areas where people are happi.

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The Chiral Switch: A Pharmaceutical Tactic to Prolong Exclusivity

Drug Patent Watch

Enantiomer Switching: A Pharmaceutical Strategy to Extend Drug Patents Enantiomer switching, also known as chiral switching, is a strategy employed […] Source

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Younger May Not Fare Better When It Comes to Leg Artery Disease

Drugs.com

TUESDAY, July 23, 2024 -- Middle-aged folks don’t necessarily fare better than seniors following urgent surgery to unclog arteries and restore blood flow to their legs, a new study warns.Adults in their 50s with peripheral artery disease (PAD) a.

Disease 59
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New tentative approval for Alembic drug dabigatran etexilate mesylate

Drug Patent Watch

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five NDAs.

Drugs 52
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Psychotherapy Via Texts Can Be Just as Effective

Drugs.com

TUESDAY, July 23, 2024 -- Folks with depression who got therapy via text or voice messages fared just as well as those who got weekly video-based telemedicine sessions with a therapist, a new trial has found.The findings "suggest that.

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New patent expiration for Sun Pharm drug WINLEVI

Drug Patent Watch

Annual Drug Patent Expirations for WINLEVI Winlevi is a drug marketed by Sun Pharm and is included in one NDA. It is available from one supplier. There are eight patents protecting this drug.

Drugs 52
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Marijuana Use While Pregnant Could Raise Odds for Complications

Drugs.com

TUESDAY, July 23, 2024 -- There's a slight but significant rise in dangerous obstetric complications for pregnant women who use marijuana, new research shows. Data from almost 317,000 pregnancies in women in California found those who used the drug.

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Understanding AWS Lambda Execution Role

Perficient: Drug Development

As we know, AWS Lambda is a serverless computing service that lets you run code without provisioning or managing servers. However, for Lambda functions to interact with other AWS services or resources, it needs permissions. This is where the AWS Lambda execution role comes into picture. An execution role is an AWS Identity and Access Management (IAM) role that Lambda assumes when it runs your lambda function.

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Extra Money Keeps Poorer Americans Out of the ER, Study Finds

Drugs.com

TUESDAY, July 23, 2024 -- It's a simple strategy that could deliver powerful health dividends: New research shows that giving cash to poor people could help them stay out of the ER.In the study, investigators followed nearly 2,900 low-income people.

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Gross-to-Net Bubble Update: 2023 Pricing Realities at 10 Top Drugmakers

Drug Channels

It’s time for Drug Channels ’ annual update on pricing at the largest pharmaceutical manufacturers. This year’s review includes the following 10 companies: Bristol Myers Squibb, Eli Lilly and Company, Genentech, GlaxoSmithKline, Merck, Novo Nordisk, Sanofi, Takeda, Teva, and UCB. You can find links to each company’s data below. These data remain inconvenient for drug pricing flat earthers (#DPFE): When rebates and discounts were factored in, brand-name drug prices again declined—or grew slowly—i

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Advancing Drug Discovery with Innovative Science and Technologies

Zobio

In person ZoBio was delighted to participate in one of the prestigious Gordon Research Conferences (GRC) which is a premier, international scientific conference dedicated to advancing the frontiers of science. This year the conference took place in New London, New Hampshire. The conference program featured a diverse array of speakers and discussion leaders from leading.

Science 40
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Whole Genome Sequencing, Proteomics, and Function Characterization of the Sinclair Nanopig™ for (Bio)Pharmaceuticals Safety Assessment

Alta Sciences

Whole Genome Sequencing, Proteomics, and Function Characterization of the Sinclair Nanopig™ for (Bio)Pharmaceuticals Safety Assessment tchichekian Tue, 07/23/2024 - 12:14 Publication White paper_Sinclair Nanopig Data_v3.

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Advancing Drug Discovery with Innovative Science and Technologies

Zobio

In person ZoBio was delighted to participate in one of the prestigious Gordon Research Conferences (GRC) held in New London, New Hampshire. The Medicinal Chemistry GRC is a premier, international scientific conference dedicated to advancing the frontiers of science. This conference emphasizes the presentation of cutting-edge and unpublished research, providing ample opportunities for discussion following.

Science 40
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Women in STEM with Juliet Williams

Drug Target Review

What inspired you to pursue a career in STEM and can you tell us about how your career journey unfolded? An early introduction to STEM in the classroom sparked my passion for biology and I’m grateful for the exposure to different scientific concepts and contexts at a young age. I wanted to make a tangible impact on the world through biology and was drawn to the challenge of scientific discovery, which led me to pursue a career in the biotech/pharma industry.

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Advancing Drug Discovery with Innovative Science and Technologies

Zobio

In person ZoBio is delighted to participate in one of the prestigious Gordon Research Conferences (GRC) held in New London, New Hampshire. The Medicinal Chemistry GRC is a premier, international scientific conference dedicated to advancing the frontiers of science. This conference emphasizes the presentation of cutting-edge and unpublished research, providing ample opportunities for discussion following.

Science 40
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Which pharmaceutical companies have the most SPCs in Slovakia?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Slovakia.

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The True Cost of Neglecting Quality Assurance: Lessons from Recent Tech Failures

Perficient: Drug Development

The Importance of Quality Assurance in Software Development The pressure to deliver software quickly and cost-effectively is among the highest priorities of business leaders. However, recent high-profile tech failures serve as stark reminders of the critical importance of robust Quality Assurance (QA) practices. As a leader in digital consulting, we recognize that cutting corners on testing can lead to far-reaching consequences that extend well beyond temporary service disruptions.