Mon.Oct 28, 2024

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Scientists can reverse brain aging in fruit flies by preventing buildup of a common protein

Science Daily: Pharmacology News

Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline. By tweaking a few very specific genes in the neurons of aging fruit flies, the researchers prevented F-actin buildup, maintained cellular recycling and extended the healthy lifespan of fruit flies by approximately 30%.

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New Hope Against a Rare, Aggressive Form of Thyroid Cancer

Drugs.com

MONDAY, Oct. 28, 2024 -- Most thyroid cancers are slow-moving and, if caught early, curable. But some patients can present with what's known as an anaplastic thyroid carcinoma (ATC) -- a rare and very aggressive tumor with a very poor prognosis.

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Dinosaurs thrived after ice, not fire, says a new study of ancient volcanism

Science Daily: Pharmacology News

The Triassic-Jurassic Extinction, 201.6 million years ago, has been considered by some to have been a fairly slow-burn event, driven by rising temperatures and ocean acidification. A new study says it was kicked off for the most part by volcanic winter.

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1 in 5 Americans' Drinking Water Tainted With PFAS Chemicals

Drugs.com

MONDAY, Oct. 28, 2024 -- More than 20% of people in the continental United States might have drinking water contaminated with “forever chemicals,” a new study suggests.Between 75 and 95 million Americans rely on groundwater that contains det.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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What animal societies can teach us about aging

Science Daily: Pharmacology News

Red deer may become less sociable as they grow old to reduce the risk of picking up diseases, while older house sparrows seem to have fewer social interactions as their peers die off, according to new research which shows humans are not the only animals to change our social behaviour as we age.

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Weed Use During Pregnancy May Harm Kids' Behavior, Thinking Skills

Drugs.com

MONDAY, Oct. 28, 2024 -- Smoking marijuana during pregnancy may quell your morning sickness, but it could also harm your child’s development, a new study warns.Cannabis exposure in the womb is associated in early childhood with poorer thinking s.

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Ozempic Curbs Kidney Disease in Obese People Without Diabetes

Drugs.com

MONDAY, Oct. 28, 2024 -- The weight-loss drug Ozempic can guard against kidney disease in obese people, a new study shows.Patients taking semaglutide -- the active agent in Ozempic and Wegovy -- had as much as a 52% reduction in kidney damage, as.

Disease 111
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Women in STEM with Veerle d’Haenens

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My first jobs after getting my engineering degree were very technical: a quality engineer for incoming raw materials, and a product development engineer. When I graduated, I had no clue about how a company, or a business was run. My parents were both teachers, in primary and secondary school, and I had not been in touch with people being active in a business environment.

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Skin Patch Uses 'Imperceptible' Electric Zaps to Heal Wounds Without Drugs

Drugs.com

MONDAY, Oct. 28, 2024 -- An experimental electric bandage might help doctors stop bacterial infections without using any drugs, a new study suggests.Imperceptible low-level electric current applied through a skin patch caused a nearly 10 times.

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Lab-grown pork gets support from sorghum grain

Science Daily: Pharmacology News

Meat grown in a lab isn't science fiction anymore. Cultured meats have existed for over a decade, and as of 2023, you might even find lab-grown chicken in restaurants (in the U.S., at least). Now, with the literal support of plant-based scaffolds, 'clean meat' options are expanding. Researchers have created a prototype cultured pork using a new material: kafirin proteins isolated from red sorghum grain.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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McDonald's Quarter Pounder Beef Patties Not Source of E. Coli Contamination

Drugs.com

MONDAY, Oct. 28, 2024 -- McDonald's Quarter Pounder beef patties have tested negative for E. coli contamination as an outbreak that has sickened 75 people in 13 states continues, the company announced Sunday.Federal health officials had already.

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Seeing a black hole's jet in a new light

Science Daily: Pharmacology News

Researchers have pored over more than two decades' worth of data from NASA's Chandra X-Ray Observatory to show there's new knotty science to discover around black holes.

Science 91
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Every Minute Counts: Speedy Defibrillator Delivery Saves Lives From Cardiac Arrest

Drugs.com

MONDAY, Oct. 28, 2024 -- Every minute spent waiting for a first shock from a defibrillator cuts the odds of surviving cardiac arrest by 6%, a new Dutch study finds."Our research shows that every minute of delay in giving the first shock has a major.

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Top 10 CDMO Services You Didn’t Know You Needed

Drug Patent Watch

The pharmaceutical industry relies heavily on Contract Development and Manufacturing Organizations (CDMOs) to streamline the drug development and manufacturing process. CDMOs provide a wide range of services that cater to the diverse needs of pharmaceutical companies, from early-stage development to commercial manufacturing.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Hospice Care Saves Medicare Lots of Money, Study Finds

Drugs.com

MONDAY, Oct. 28, 2024 -- Hospice care is a compassionate and heartfelt enterprise, involving a medical team dedicated to maintaining a person’s comfort and dignity as they face the final curtain.Now, new research shows hospice is also incredibly c.

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Biotech Risk Cycles: Assets And Platforms

LifeSciVC

Today’s market likes products. Platforms aren’t in vogue anymore. Investors, especially in the public markets, only want late stage de-risked assets. Pharma only seems to be buying these kinds of asset. VCs need to focus on clinical stage companies. Or so the conventional wisdom goes in the equity capital markets these days. While it may be the prevailing wind, an innovation ecosystem that allocates capital only to later stage assets risks exhibiting a rather unhealthy blend of investment myopia

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AbbVie to acquire a J&J-backed brain drugmaker for $1.4B

BioPharma Drive: Drug Pricing

Buying Aliada Therapeutics would hand AbbVie a clinical-stage Alzheimer’s medicine and a drugmaking technology that may be useful for a variety of brain diseases.

Disease 92
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Evidence mounts for dark energy from black holes

Science Daily: Pharmacology News

Researchers have strengthened the case that matter becomes dark energy when massive stars collapse and become black holes.

Research 101
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Interoception- The Sixth Sense Behind the Brain-Body Connection

keypoint

The Keystone Symposia on Interoception will explore emerging discoveries of neural communications between the body and the brain.

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Why langurs drink salt water

Science Daily: Pharmacology News

A new study shows the remarkable adaptability of the critically endangered Cat Ba langurs. Despite low genetic diversity, the langurs have retained key genetic traits that help them survive in their isolated environment on Cat Ba Island in Vietnam. One of these remarkable adaptations is the ability to drink salt water.

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Don’t let your samples slip: Why every clinical trial needs biospecimen management

BioPharma Drive: Drug Pricing

Assure the integrity and efficiency of your clinical trials with support from a Biospecimen Manager.

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A faster, better way to train general-purpose robots

Science Daily: Pharmacology News

Inspired by large language models, researchers developed a training technique that pools diverse data to teach robots new skills.

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FDA Guidance Outlines a Framework for the Evaluation of Long-Term Neurodevelopmental Safety Studies in Neonatal Product Development

FDA Law Blog: Drug Discovery

By Mark A. Tobolowsky — The neonatal period is a unique and complex period of rapid growth and development throughout the body, thus creating unique and complex challenges in medical product development for this population. These changes may affect the safety of a product used in this population in ways that are not reflected in studies of the same product in other populations.

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Pythons can swallow even bigger prey than scientists realized

Science Daily: Pharmacology News

Burmese pythons can consume prey even larger than scientists realized, according to a new study. That means more animals are on the menu across southern Florida, where the nonnative, invasive snakes have decimated populations of foxes, bobcats, raccoons and other animals.

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Recent changes to Inventory

Collaborative Drug

Inventory Expiration Alerts A new sample level metadata field is available to track the expiration date of a sample. Edit existing samples to add an expiration date or use the field for new sample registrations. Email alerts can now be set by users for samples that are near or past their expiration date.

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Celebrating National Ergonomics Month

NIOSH Science Blog: Drugs

October is National Ergonomics Month, a time to raise awareness about the importance of designing workplaces to fit people better. Ergonomics focuses on creating tools, tasks, and environments that improve comfort, reduce injuries, and promote the health and well-being of workers. Ergonomics research and interventions can help prevent common workplace musculoskeletal injuries, such as back pain, sore muscles, and repetitive strain injuries.

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Monte Rosa joins with Novartis in ‘molecular glue’ drug deal

BioPharma Drive: Drug Pricing

Novartis follows cross-town rival Roche in partnering with Monte Rosa Therapeutics on so-called molecular glue degraders that can target “undruggable” proteins.

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Perficient Included in IDC Market Glance: Digital Business Professional Services Report

Perficient: Drug Development

Today’s digital landscape is dynamic. It favors speed over size, agility over efficiency, and cross-functional collaboration over rigid structures. You must be prepared to adapt and scale your teams as priorities shift. Moving forward requires a comprehensive digital strategy that outlines the capabilities, agility, and alignment needed to stay ahead of digital disruption.

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How pharmaceutical companies can leverage print to remain agile and competitive

BioPharma Drive: Drug Pricing

Learn why print remains a preferred channel for healthcare communications, and how printed materials can help build relationships with patients, develop brand loyalty and maintain brand consistency.

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Being Too Heavy, Too Skinny in Childhood Can Impair Lung Function

Drugs.com

TUESDAY, Oct. 29, 2024 -- Here's another good reason to help your child reach and maintain a healthy weight: A new study warns that kids who are either too skinny or too fat are at risk for impaired lung function.However, if their weight can be.

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A Comprehensive Guide to Creating Tabular Reports in Salesforce

Perficient: Drug Development

Hello Trailblazers! Salesforce provides powerful reporting tools to help businesses analyze data, track performance, and make informed decisions. In the previous part of this blog we learnt about different types of reports available in Salesforce. Tabular Reports are the simplest and most straightforward way to display your data in rows and columns.

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Top Life Science Resources for Fall 2024

Alta Sciences

Top Life Science Resources for Fall 2024 pmjackson Mon, 10/28/2024 - 17:59 There’s a lot of life science content out there, so for your convenience, we’ve curated a selection of expert insights, tips, case studies, and scientific and regulatory information. Catch up on what you might have missed below! TOP NONCLINICAL SCIENTIFIC RESOURCES Webinar : Innovative Surgical Solutions in Safety Assessment Studies Explore how innovative surgical solutions are enhancing nonclinical safety assessments.

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Custom Salesforce Path LWC

Perficient: Drug Development

Creating a seamless and intuitive user experience is crucial for any application. In Salesforce, a great way to guide users through different stages of a process is by using progress indicators. In this blog post, I’ll show you how to build a Custom Salesforce Path using the lightning-progress-indicator component in Lightning Web Components (LWC). This example will focus on a user details form, demonstrating how to navigate between sections with a clear visual indicator.

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