Chemical Biology and Drug Design

JANUARY 7, 2024

The present paper showed an apoptosis- and ferroptosis-inducing action of chrysophanol on gastric cancer cells. The tumour killing effects of chrysophanol possible owing to its targeted regulation on mTOR. Further investigations are required to confirm these results in vivo and a vast of studies are needed before the clinical use of chrysophanol in cancer treatment.

Regulations 100

Regulations Treatment Research 100

SCIENMAG: Medicine & Health

JANUARY 7, 2024

Orlando, Fla – More than two in five U.S. adults suffer from obesity, an epidemic that continues to trend upward. While bariatric surgery is an extremely effective treatment option, a new national survey by Orlando Health reveals common stigmas that may deter those who qualify for surgery from pursuing the treatment they need.

Treatment 86

Treatment 86

Chemical Biology and Drug Design

JANUARY 7, 2024

With network pharmacology, this study analyzed the biological functions the main bioactive components of Buyang Huanwu decoction (BYHWT) in treating atherosclerosis. The 325 targets of BYHWT was obtained, and 8 core targets were screened, including AKT, JUN, MAPK1, PIK3CA, EGFR, ESR1, SRC, and TP53. Molecular docking was then conducted to analyze the binding affinity between the active components of BYHWT and the core targets, and in vitro assays were applied to validate the function of baicalei

Treatment 100

Treatment Regulations Disease Research 100

SCIENMAG: Medicine & Health

JANUARY 7, 2024

Certain populations of mosquitoes are more heat tolerant and better equipped to survive heat waves than others, according to new research from Washington University in St. Louis.

Research 81

Research 81

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Chemical Biology and Drug Design

JANUARY 7, 2024

Triptolide restrains non-small cell lung cancer cell proliferation, invasion, stemness, and glycolysis in vitro, as well as reduces tumor growth in vivo, by PFKFB2-mediated PI3K/AKT pathway. Abstract Triptolide (TP) has been found to have anti-tumor effects. However, more potential molecular mechanisms of TP in the progression of non-small cell lung cancer (NSCLC) deserve further investigation.

Treatment 100

Treatment Research 100

Drug Patent Watch

JANUARY 7, 2024

This chart shows the pharmaceutical companies with the most patents in Hong Kong. Patents must be filed in each country (or, in some cases regional patent office) where patent protection… The post Which pharmaceutical companies have the most drug patents in Hong Kong? appeared first on DrugPatentWatch - Make Better Decisions.

Pharmaceutical Companies 73

Pharmaceutical Companies Pharmaceuticals Drugs 73

Drug Patent Watch

JANUARY 7, 2024

Annual Drug Patent Expirations for LAZANDA Lazanda is a drug marketed by Btcp Pharma and is included in one NDA. There are five patents protecting this drug. This drug has… The post New patent expiration for Btcp Pharma drug LAZANDA appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 64

Drugs Marketing 64

FDA Law Blog: Drug Discovery

JANUARY 7, 2024

By McKenzie E. Cato — New Year’s is often associated with baby New Year and with resolutions, which in a convoluted way got us thinking about post-approval pregnancy studies. Lots of us start the new year with a resolution. Is it a commitment, or a requirement, and does the difference matter? For post-approval pregnancy studies, it most certainly does.

Marketing 59

Marketing FDA Regulations Pharmacokinetics 59