Sun.Nov 10, 2024

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Exploration of the Active Components and Mechanism of Jiegeng (Platycodonis Radix) in the Treatment of Influenza Virus Pneumonia Through Network Pharmacology Analysis and Experimental Verification

Chemical Biology and Drug Design

Combined with network pharmacology and experimental verification, this study found that platycodin D and luteolin in Jiegeng ( Platycodonis Radix ) may regulate inflammation through the IL-17 signaling pathway to treat influenza virus pneumonia. ABSTRACT This study aimed to explore the pathogenesis of platycodin D and luteolin, which are both active components in Jiegeng ( Platycodonis Radix ), in the treatment of influenza virus pneumonia through network pharmacology analysis combined with expe

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Regulator and Funder? FDA’s Orphan Products Grants Program awards significant funding to help move promising treatments through clinical development

FDA Law Blog: Drug Discovery

By Sarah Wicks & James E. Valentine — The U.S. Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.

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Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation

Covalent Modifiers

Gregory B. Craven, Hang Chu, Jessica D. Sun, Jordan D. Carelli, Brittany Coyne, Hao Chen, Ying Chen, Xiaolei Ma, Subhamoy Das, Wayne Kong, Adam D. Zajdlik, Kin S. Yang, Solomon H. Reisberg, Peter A. Thompson, J. Russell Lipford & Jack Taunton Nature, 2024 [link] Somatic alterations in the oncogenic kinase AKT1 have been identified in a broad spectrum of solid tumours.

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Boost Your Customer Support to the Next Level with Salesforce Agentforce – Here’s How!

Perficient: Drug Development

Imagine a busy call center where customer support agents are helping customers resolve issues, answer questions, and provide product guidance. But instead of switching between multiple systems, agents have everything they need in one place: customer information, order history, communication tools, and real-time updates. This is made possible by Salesforce Agentforce , a platform designed to streamline customer service, boost efficiency, and create a better experience for both agents and customer

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Drug Patent Expirations for the Week of November 10, 2024

Drug Patent Watch

PONVORY (ponesimod) Vanda pharms inc Patent: 9,000,018 Expiration: Nov 16, 2024 See More … Source

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Universal Design for Cognitive Disabilities in Healthcare -Clear and Simple Communication – 1

Perficient: Drug Development

One of the fundamental principles of universal design in healthcare is ensuring clear and simple communication. For individuals with cognitive disabilities, this principle is crucial as it helps them understand and engage with their healthcare more effectively. Here’s how healthcare providers can implement clear and simple communication: The Importance of Clear and Simple Communication Individuals with cognitive disabilities often face challenges in processing complex information.