Sun.Nov 10, 2024

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Regulator and Funder? FDA’s Orphan Products Grants Program awards significant funding to help move promising treatments through clinical development

FDA Law Blog: Drug Discovery

By Sarah Wicks & James E. Valentine — The U.S. Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.

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Drug Patent Expirations for the Week of November 10, 2024

Drug Patent Watch

PONVORY (ponesimod) Vanda pharms inc Patent: 9,000,018 Expiration: Nov 16, 2024 See More … Source

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Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation

Covalent Modifiers

Gregory B. Craven, Hang Chu, Jessica D. Sun, Jordan D. Carelli, Brittany Coyne, Hao Chen, Ying Chen, Xiaolei Ma, Subhamoy Das, Wayne Kong, Adam D. Zajdlik, Kin S. Yang, Solomon H. Reisberg, Peter A. Thompson, J. Russell Lipford & Jack Taunton Nature, 2024 [link] Somatic alterations in the oncogenic kinase AKT1 have been identified in a broad spectrum of solid tumours.

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Exploration of the Active Components and Mechanism of Jiegeng (Platycodonis Radix) in the Treatment of Influenza Virus Pneumonia Through Network Pharmacology Analysis and Experimental Verification

Chemical Biology and Drug Design

Combined with network pharmacology and experimental verification, this study found that platycodin D and luteolin in Jiegeng ( Platycodonis Radix ) may regulate inflammation through the IL-17 signaling pathway to treat influenza virus pneumonia. ABSTRACT This study aimed to explore the pathogenesis of platycodin D and luteolin, which are both active components in Jiegeng ( Platycodonis Radix ), in the treatment of influenza virus pneumonia through network pharmacology analysis combined with expe

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Boost Your Customer Support to the Next Level with Salesforce Agentforce – Here’s How!

Perficient: Drug Development

Imagine a busy call center where customer support agents are helping customers resolve issues, answer questions, and provide product guidance. But instead of switching between multiple systems, agents have everything they need in one place: customer information, order history, communication tools, and real-time updates. This is made possible by Salesforce Agentforce , a platform designed to streamline customer service, boost efficiency, and create a better experience for both agents and customer

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Universal Design for Cognitive Disabilities in Healthcare -The Power of Plain Language–2

Perficient: Drug Development

A cornerstone of universal design in healthcare is the use of plain language. For individuals with cognitive disabilities, plain language transforms complex medical information into understandable and actionable insights, ensuring they can make informed decisions about their health. Here’s how healthcare providers can implement plain language effectively: The Importance of Plain Language Using plain language in healthcare communication is essential for ensuring that patients with cognitive disab