Tue.Nov 19, 2024

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Scientists use ancient DNA to shed light on adaptation of early Europeans

Science Daily: Pharmacology News

Leveraging a unique statistical analysis and applying it to ancient DNA extracted from human skeletal remains, a team of researchers has revealed new insights into how ancient Europeans adapted to their environments over 7,000 years of European history.

DNA 292
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Want to Lower Chemical Exposures in Pregnancy? Quit Nail Polish, Makeup and Hair Dye

Drugs.com

TUESDAY, Nov. 19, 2024 -- Women who won't leave the house without makeup or a spritz of hairspray may want to think twice about those habits when they're pregnant or breastfeeding.New research links these and other personal care products, including.

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The chilling sound of the Aztec death whistle

Science Daily: Pharmacology News

The Aztec skull whistle produces a shrill, screaming sound. A study shows that these whistles have a disturbing effect on the human brain. The Aztecs may have deliberately used this effect in sacrificial rituals.

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Drug Discovery Industry Roundup with Barry Bunin — November, 19 2024

Collaborative Drug

Drug Discovery Industry Roundup with Barry Bunin — November, 6 2024

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Astronomers discover first pairs of white dwarf and main sequence stars in clusters, shining new light on stellar evolution

Science Daily: Pharmacology News

Astronomers have discovered the first pairs of white dwarf and main sequence stars -- 'dead' remnants and 'living' stars -- in young star clusters. This breakthrough offers new insights on an extreme phase of stellar evolution, and one of the biggest mysteries in astrophysics.

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New ion speed record holds potential for faster battery charging, biosensing

Science Daily: Pharmacology News

A speed record has been broken using nanoscience, which could lead to a host of new advances, including improved battery charging, biosensing, soft robotics and neuromorphic computing. Scientists have discovered a way to make ions move more than ten times faster in mixed organic ion-electronic conductors. These conductors combine the advantages of the ion signaling used by many biological systems, including the human body, with the electron signaling used by computers.

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Ablation Best Treatment for Rapid Heartbeat in Heart Attack Survivors

Drugs.com

TUESDAY, Nov. 19, 2024 -- New research suggests that a procedure now regarded as Plan B when patients have episodes of rapid heartbeat after a heart attack should be the go-to treatment.Ablation is a minimally invasive procedure to treat abnormal.

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Under-the-skin Keytruda comparable to infused version in Phase 3 study, Merck says

BioPharma Drive: Drug Pricing

Merck plans to discuss the data with regulators as it lags rivals Roche and Bristol Myers in bringing forward a subcutaneous form of its cancer drug.

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Most of the World's Cities Lack Enough Trees to Cool, Calm Residents

Drugs.com

TUESDAY, Nov. 19, 2024 -- As climate changes sends summer temperatures higher worldwide, new research finds most urban residents don't have a key source of cooling shade: trees.A study of eight cities around the globe found that only two -- Seattle.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Incyte shares sink on setback for drugs acquired in $750M buyout

BioPharma Drive: Drug Pricing

The company paused testing of one candidate acquired in its April deal for Escient and scrapped another in a blow to its diversification plans.

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Newer Blood Thinner, Edoxaban, Cuts Odds for Stroke After Heart Valve Surgery

Drugs.com

TUESDAY, Nov. 19, 2024 -- Japanese researchers say they have found a pill that works as well as existing medication to prevent blood clots after heart valve surgery, with fewer trips to the doctor. Unlike warfarin, the standard treatment, edoxaban.

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Astellas application rejected by FDA; Cytokinetics strikes licensing deal with Bayer

BioPharma Drive: Drug Pricing

The agency turned back Astellas’ attempt to update its drug Izervay’s labeling. Elsewhere, former NCI director Ned Sharpless founded a new startup and Novartis licensed another radiopharma drug.

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Climate Change Is Pushing More People to Get X-rays, CT Scans

Drugs.com

TUESDAY, Nov. 19, 2024 -- There's yet another downside to global warming: Higher health care expenditures for medical scans on hot days. So report Canadian researchers who discovered that periods of heat and air pollution bumped up demand for.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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J&J pill clears skin in two late-stage psoriasis studies

BioPharma Drive: Drug Pricing

The drug, called icotrokinra and developed together with Protagonist Therapeutics, is an oral peptide designed to tamp down the inflammation involved in psoriasis and other immune diseases.

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Adding Blood Thinners to A-fib Treatment Won't Prevent Strokes, Help Cognition

Drugs.com

TUESDAY, Nov. 19, 2024 -- People using blood thinners to control their heart rhythm shouldn't expect the medications to head off thinking declines as well, new research suggests.The study, presented Saturday at a meeting of the American Heart.

Treatment 130
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New Antibodies in the Lab Animation!

addgene Blog

Thinking about using antibody-based applications in your experiment.but not sure where to start or what your options are? Addgene's latest animation is here to help!

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Newer Blood Thinner Cuts Odds for Stroke After Heart Valve Surgery

Drugs.com

TUESDAY, Nov. 19, 2024 -- Japanese researchers say they have found a pill that works as well as existing medication to prevent blood clots after heart valve surgery, with fewer trips to the doctor.Unlike warfarin, the standard treatment, edoxaban.

Treatment 130
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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How cells habituate

Science Daily: Pharmacology News

Up until recently, habituation -- a simple form of learning -- was deemed the exclusive domain of complex organisms with brains and nervous systems, such as worms, insects, birds, and mammals. But a new study offers compelling evidence that even tiny single-cell creatures such as ciliates and amoebae, as well as the cells in our own bodies, could exhibit habituation akin to that seen in more complex organisms with brains.

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There's Been a Big Improvement in Lung Cancer Survival

Drugs.com

TUESDAY, Nov. 19, 2024 -- More people with lung cancer are living longer, but it remains America's deadliest cancer, a new state-by-state report shows."There is more work to do, but I am incredibly optimistic about the future of lung cancer care,".

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The Emotional Conclusion : Project Estimating (Part 4)

Perficient: Drug Development

This post is the third in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion The emotional finale is here! Don’t worry, this isn’t about curling up in a ball and crying – we’ve already done that. This final installment of my series on project estimating is all about navigating the emotions of everyone involved and trying to avoid frustration.

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U.S. Alcohol-Linked Deaths Doubled in 20 Years

Drugs.com

TUESDAY, Nov. 19, 2024 -- Alcohol-related deaths have surged in the United States, nearly doubling over 20 years, and a growing number of victims are women, a new study warns."Our study found significant gender differences in alcohol-related [death.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The Future of Partnerships in Generic Drug Development

Drug Patent Watch

The pharmaceutical industry is undergoing significant transformations, particularly in the realm of generic drug development. Recent trends and advancements in technology, research, and collaboration are reshaping the landscape of generic drug development, leading to new opportunities and challenges for pharmaceutical companies.

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Why Alarm Is Easing Over a Rise in Pancreatic Cancer Among the Young

Drugs.com

TUESDAY, Nov. 19, 2024 -- Experts have been concerned by rising rates of pancreatic cancer in young adults, but new research reveals the jump in cases has not been accompanied by any increase in deaths from the disease.Why? According to the.

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Large Chains’ Position in 2025’s Part D Pharmacy Networks: Supermarkets Take the Lead in a Shrinking PDP Market

Drug Channels

In Medicare Part D in 2025: Preferred Pharmacy Networks Fade in a Collapsing PDP Market , I documented the Inflation Reduction Act’s (IRA) disruption to Medicare Part D prescription drug plans (PDPs). Today, we examine the seven largest retail chains’ participation in the 12 major 2025 Part D networks that the five largest plan sponsors will offer. As always, we provide you with a handy table for tallying each chain’s participation and changes from 2024 to 2025.

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Judge Declares Wyoming's Abortion Bans Unconstitutional

Drugs.com

TUESDAY, Nov. 19, 2024 -- Two Wyoming abortion bans, including the first state law to prohibit the use of abortion pills, violate the state's constitution, a judge ruled Monday.In her decision, Judge Melissa Owens, of Teton County District Court.

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Universal Design for Cognitive Disabilities in Healthcare-Embracing Interactive Communication-5

Perficient: Drug Development

Interactive communication is a key component of universal design in healthcare. It ensures that patients with cognitive disabilities are actively engaged in their care, fostering better understanding, retention, and overall satisfaction. Here’s how healthcare providers can effectively implement interactive communication: The Importance of Interactive Communication Interactive communication involves a two-way exchange where patients are not just passive recipients but active participants in the c