Science Daily: Pharmacology News

OCTOBER 31, 2024

Children who experienced sugar restrictions during their first 1,000 days after conception had up to 35% lower risk of developing type 2 diabetes and as much as 20% less risk of hypertension as adults. The researchers used contemporary data from the U.K. Biobank, a database of medical histories and genetic, lifestyle and other disease risk factors, to study the effect of those early-life sugar restrictions on health outcomes of adults conceived in the U.K. just before and after the end of wartim

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Disease Research 125

BioPharma Drive: Drug Pricing

OCTOBER 31, 2024

In an investor presentation, executives hinted at the possibility of seeking an accelerated approval of trontinemab if it can significantly lower levels of amyloid in a Phase 3 trial.

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Trials Drugs 120

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Whooping cough is on the rise in the United States, with cases surging across the nation.It’s important to remember that whooping cough, also known as pertussis, can impact adults as well as kids, according to Infectious D.

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Science Daily: Pharmacology News

OCTOBER 31, 2024

Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses. In a new study, researchers identified a protein in mammals that welcomes arteriviruses into host cells to start an infection. The team also found that an existing monoclonal antibody that binds to this protein protects cells from viral infection.

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Virus Research 108

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Doctors in New York City are describing the first known U.S. cases of sexually transmitted ringworm, which can cause a nasty rash that can take months to bring under control.Despite the name, ringworm isn't any kind of.

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Doctors 105

Science Daily: Pharmacology News

OCTOBER 31, 2024

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- are edited by the spliceosome. The sheer number of components involved has meant the scientific feat took more than a decade to complete. The research reveals many new drug targets that could benefit a wide spectrum of diseases including most types of cancer, neurodegenerative conditions and genetic

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Disease Research Drugs 108

Science Daily: Pharmacology News

OCTOBER 31, 2024

According to Bredt's rule, double bonds cannot exist at certain positions on organic molecules if the molecule's geometry deviates too far from what we learn in textbooks. This rule has constrained chemists for a century. Chemists have now shown how to make molecules that violate Bredt's rule, allowing chemists to find practical ways to make and use them in reactions.

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Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- A new guidance issued jointly by groups representing U.S. surgeons, anesthesiologists and gastroenterologists affirms that most people taking popular GLP-1 weight-loss meds can keep taking them in the weeks before a.

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BioPharma Drive: Drug Pricing

OCTOBER 31, 2024

The biotech expects three Phase 2 readouts in urticaria and eczema over the next two years, and will keep its “options open” regarding an IPO, its CEO said.

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Drugs 106

Science Daily: Pharmacology News

OCTOBER 31, 2024

Echolocating bats have been found to possess an acoustic cognitive map of their home range, enabling them to navigate over kilometer-scale distances using echolocation alone.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Amid an ongoing outbreak of bird flu in poultry and dairy cows in the United States, a case of H5N1 has now been confirmed for the first time in a pig."The U.S. Department of Agriculture [USDA] and Oregon state veterinary.

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Drug Patent Watch

OCTOBER 31, 2024

The pharmaceutical industry has undergone significant transformations in recent years, driven by the COVID-19 pandemic and the subsequent need for rapid innovation and adaptation.

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Pharmaceuticals 97

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Don’t automatically throw out that old COVID-19 at-home test you just came across in your medicine cabinet.It might still be good, according to the U.S. Food and Drug Administration.Some over-the-counter COVID tests have h.

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FDA Drugs 98

Science Daily: Pharmacology News

OCTOBER 31, 2024

Researchers have developed a model to calculate how quickly or slowly an organism should ideally learn in its surroundings. An organism's ideal learning rate depends on the pace of environmental change and its life cycle, they say.

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Research 92

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Clinical Trials

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- If anxiety over this year’s presidential election is keeping you up at night, you’re not alone.About 17% of all U.S. adults -- a striking 45 million Americans -- say the election has negatively impacted their sleep, acc.

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addgene Blog

OCTOBER 31, 2024

If you’re looking for an antibody that works for your experiment, you may be overwhelmed by options — or not know where to start looking to find one. Luckily, there are websites that can help: Antibody data repositories, which share validation data, and antibody search engines, which allow you to search many different antibody catalogs at the same time.

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Engineering 76

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- A person battling multiple sclerosis spent an average of $750 in out-of-pocket fees on medicines in 2012, but by 2021 that same patient spent $2,378 annually, a new report finds.Out-of-pocket costs for drugs for.

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Drugs 98

sptlabtech

OCTOBER 31, 2024

We believe automation should be accessible to as many scientists as possible, regardless of their automated liquid handling expertise. That's why from the beginning, we've put usability at the forefront of firefly software development. Our goal has always been to deliver an intuitive, easy-to-use liquid handling solution that simplifies workflows and maximizes productivity in the lab.

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Compliance Engineering Production Regulations 59

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- In a finding that challenges conventional thinking on when people with failing heart valves but no symptoms should get surgery, a new study suggests these patients would fare far better if they had their valves replaced.

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thought leadership

OCTOBER 31, 2024

On January 31, 2022, the EU Clinical Trials Regulation 536/2014 (CTR) came into force with a transition period of three years. Now, as that transition period comes to a close, the process and need for registering new clinical trials is old news to sponsors, however there's one more step needed to ensure compliance. Clinical trials registered under the previous EU Clinical Trials Directive (EU-CTD), that are expected to continue after January 30, 2025, are now called Transitional Trials, and thes

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Clinical Trials Regulations Trials Compliance 59

Reprocell

OCTOBER 31, 2024

Welcome to our new blog series on a REPROCELL 3D tissue engineering platform powered by Alvetex® technology. This series aims to inform and educate the research community and industry partners about the significance and benefits of cutting-edge bioengineered 3D human tissue model systems, which may be instrumental in facilitating translational research studies and accelerating the development of drugs and products.

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Engineering Production Research Drugs 59

BioPharma Drive: Drug Pricing

OCTOBER 31, 2024

The immune disease drug developer expects to raise $300 million in a private financing set to close before its combination with the struggling Aerovate.

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Drug Development Disease Drugs 60

Broad Institute

OCTOBER 31, 2024

A Comparative Genomics Strategy To Discover Mechanisms of Cellular Resilience By Rose Circeo October 31, 2024 Breadcrumb Home A Comparative Genomics Strategy To Discover Mechanisms of Cellular Resilience The Primer on Medical and Population Genetics is a series of weekly lectures on genetics topics related to human populations and disease. Experts from across the Medical and Population Genetics community at the Broad Institute give in-depth introductions to research in human genetics through ove

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Bioethics Disease Research 52

BioPharma Drive: Drug Pricing

OCTOBER 31, 2024

Patient advocates are hoping for change under new director Michelle Tarver, while industry groups hope she will build on former director Jeff Shuren’s leadership.

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Fierce BioTech

OCTOBER 31, 2024

The Impact of Enzymatic DNA Synthesis on Compact Protein Circuitry for Regulating Protein Secretion Across Multiple Levels of the Central Dogma pesurya Thu, 10/31/2024 - 12:03 Tue, 12/10/2024 - 12:00 Resource Type Webinar Dan Lin-Arlow Connor Clayton Call Promotion Start Mon, 11/04/2024 - 08:30 Promotion End Sun, 05/04/2025 - 08:30 Duration 60 Minutes In recent decades, mammalian synthetic biology has shown that key principles of biological regulation can be rewritten to control gene expression

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DNA Regulations 52

PPD

OCTOBER 31, 2024

As the pharmaceutical industry continues to evolve, drug developers encounter new challenges and opportunities in their pursuit of innovation. From adapting to complex new trial designs to embracing cutting-edge technologies, staying ahead requires a deep understanding of the current landscape. In response, the PPD clinical research business of Thermo Fisher Scientific conducted its third global survey of 150 drug developers to capture a comprehensive view of these evolving trends.

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Drug Development Clinical Trials Trials Drugs 52

Advarra

OCTOBER 31, 2024

It’s a no-brainer: To grow your business, you need to negotiate and collect the funds you deserve for work performed. Part of the process is understanding the true costs of your work prior to budget negotiation. This includes all direct and indirect costs, and typically includes: Personnel costs: salaries, overtime, training, and additional staffing if needed.

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Research Trials Compliance Clinical Trials 52

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Scans using lasers and ultrasound can pick up signs of a malaria infection through the skin, without the need for a blood draw, Yale researchers report.The technology, called Cytophone, could be a real boon for developing.

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Research 52

Perficient: Drug Development

OCTOBER 31, 2024

The Federal Deposit Insurance Corporation (“FDIC”) recently announced that it is providing financial institutions additional time to get new process and systems in place by extending the compliance date for the new FDIC signage and advertising rule (Part 328, subpart A) from January 1, 2025, to May 1, 2025. The final rule established a new black and navy-blue FDIC official digital sign shown below.

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Compliance Production 52

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- Sugar overload is a real danger on Halloween, as piles of candy prove a powerful temptation to both Trick-or-Treaters and the folks handing out the goodies.Too many sweet treats can instigate a blood sugar spike followed.

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Perficient: Drug Development

OCTOBER 31, 2024

Discover the world of Drupal, a flexible and powerful content management system (CMS) that empowers you to create stunning websites and web applications. This comprehensive guide will introduce you to the core concepts of Drupal, from its modular architecture to its robust security features. Learn how to build dynamic, scalable, and SEO-friendly websites without writing complex code.

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Engineering 52

Drugs.com

OCTOBER 31, 2024

THURSDAY, Oct. 31, 2024 -- The COVID-19 pandemic appears to have created a nation of homebodies in the United States, a new study finds.People are spending nearly an hour less each day doing activities outside the home, researchers reported Oct. 31.

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Research 52

Drug Target Review

OCTOBER 31, 2024

As a woman in STEM, what unique perspectives or strengths do you believe you bring to your work? Everyone brings unique perspectives and strengths regardless of gender. Specifically, for me, being a female in STEM and having often been the only female in a room, on or leading a team, or within management has allowed me to build resilience, confidence and strategies for ensuring my voice is heard in these situations.

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