Thu.May 16, 2024

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Investors put $400M into biotech licensing obesity drugs from China

BioPharma Drive: Drug Pricing

The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.

Licensing 142
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New gene delivery vehicle shows promise for human brain gene therapy

Broad Institute

New gene delivery vehicle shows promise for human brain gene therapy By Allessandra DiCorato May 16, 2024 Breadcrumb Home New gene delivery vehicle shows promise for human brain gene therapy Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.

Therapies 137
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Scientists use generative AI to answer complex questions in physics

Science Daily: Pharmacology News

Researchers used generative AI to develop a physics-informed technique to classify phase transitions in materials or physical systems that is much more efficient than existing machine-learning approaches.

Research 133
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Plant-Based Diets Lower Risk of Heart Trouble, Cancer and Death

Drugs.com

THURSDAY, May 16, 2024 -- Following a vegetarian or vegan diet might just buy you a longer, healthier life, a new review finds.Staying away from meat was tied to a reduced risk of heart disease, cancer and early death, researchers reported in a.

Disease 130
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New gene delivery vehicle shows promise for human brain gene therapy

Science Daily: Pharmacology News

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds to a well-studied protein in the blood-brain barrier, the scientists say it has a good chance at working in patients.

Therapies 129
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Biogen, Ionis shelve ALS drug following study failure

BioPharma Drive: Drug Pricing

While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.

Drugs 128

More Trending

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Detailed trial data show Bayer drug alleviates menopause symptoms

BioPharma Drive: Drug Pricing

Full study results disclosed ahead of a medical meeting showed elinzanetant consistently reduced the frequency and severity of hot flashes.

Trials 122
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A powerful tool speeds success in achieving highly efficient thermoelectric materials

Science Daily: Pharmacology News

Thermoelectric materials could play an important role in the clean energy transition, as they can produce electricity from sources of heat that would otherwise go to waste. Researchers report a new approach to efficiently predict when thermoelectric materials will have improved performance in converting heat into electricity.

Research 123
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Lilly’s once-weekly insulin matches daily shots in late-stage tests

BioPharma Drive: Drug Pricing

The results, which showed Lilly’s drug was as effective at controlling blood sugar as standard injections, come as Novo Nordisk seeks approval for a competing once-weekly insulin.

Drugs 122
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Why do we overindulge?

Science Daily: Pharmacology News

If you tend to do other things or get distracted while eating dinner, you may be running the risk of over-consuming everyday pleasures later, possibly because the distraction caused you to enjoy yourself less, according to new research.

Research 122
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Lymphoma: Know Your Treatment Options

Drugs.com

THURSDAY, May 16, 2024 -- For anyone newly diagnosed with blood cancers known as lymphomas, their first question might be: What treatments can help?Of course, there have been big advances in chemotherapy against the disease, but treatments now go.

Treatment 111
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Otters, especially females, use tools to survive a changing world

Science Daily: Pharmacology News

Sea otters are one of the few animals that use tools to access their food, and a new study has found that individual sea otters that use tools -- most of whom are female -- are able to eat larger prey and reduce tooth damage when their preferred prey becomes depleted.

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Cream Cheese From Aldi, Hy-Vee Stores Recalled Due to Salmonella Risk

Drugs.com

THURSDAY, May 16, 2024 -- Two major supermarket chains, Aldi and Hy-Vee, are recalling brands of cream cheese because of a potential risk for salmonella.No actual illnesses linked to the products have yet been reported, but Hy-Vee said it's.

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How neighboring whale families learn each other's vocal style

Science Daily: Pharmacology News

Researchers have developed a method to investigate sperm whale communication by determining their vocal style, finding that groups living in close proximity can develop similar styles to each other.

Research 111
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Immunotherapy Before and After Surgery Boosts Lung Cancer Survival

Drugs.com

THURSDAY, May 16, 2024 -- Immunotherapy can boost the survival of early-stage lung cancer patients eligible for surgery when it’s combined with chemotherapy, a new clinical trial reports.Those who got immunotherapy before and after surgery --.

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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

COVID took the world by stunned surprise – but, to quote an old Who song, we won’t be fooled again. That’s thanks to accelerated genome sequencing technologies, expanded laboratory capabilities, and interacting infrastructure on a global level. These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and

Virus 98
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Brain Decline, Dementia Common Among Older American Indians

Drugs.com

THURSDAY, May 16, 2024 -- Higher rates of blood vessel-damaging conditions like hypertension or diabetes may be driving up rates of cognitive decline and dementia among older American Indians, new research shows.The study found that 54% of American.

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Antibodies 101: Flow Compensation

addgene Blog

In flow cytometry, compensation is the process of correcting spillover from one fluorescent channel to another. When you label your samples with multiple antibodies, the fluorescent probes on the antibodies may have similar emission spectra, meaning they will emit fluorescent light at similar wavelengths (See this handy emission spectra chart to find your antibody's spectra ).

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Dreams Might Help You Process Bad Experiences

Drugs.com

THURSDAY, May 16, 2024 -- A good night’s sleep helps clear the cobwebs from your mind, and researchers now think they’ve figured out how dreaming helps.

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Roche keeps pace in obesity drug field with early study data

BioPharma Drive: Drug Pricing

A drug Roche acquired in a buyout of Carmot Therapeutics and that works similarly to Zepbound helped people lose nearly 19% of their body weight in a Phase 1 trial.

Drugs 78
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Stroke, Migraine, Alzheimer's: Climate Change Will Likely Make Them Worse

Drugs.com

THURSDAY, May 16, 2024 -- Climate change is likely to make brain conditions like stroke, migraine, Alzheimer’s disease, epilepsy and multiple sclerosis even worse, a new review warns.The potential effects of a changing climate is likely to be.

Disease 98
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The promise of therapeutics from molecules within our body

Drug Target Review

The body’s ability to maintain homeostasis in chronic inflammatory and autoimmune diseases is a defining feature of good health, and a goal is largely neglected by modern medicine. Patients deserve better than just symptom management. Symptom-based treatment is often accompanied by undesirable side effects. This suggests that the field of drug discovery is primed for a paradigm shift in the fundamental strategy of how diseases are treated.

Disease 64
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Mediterranean Diet Could Be a Stress-Buster, Study Finds

Drugs.com

THURSDAY, May 16, 2024 -- The Mediterranean diet has already been shown to be great for a person’s physical health, but new research finds that following the Mediterranean diet also can lift your mood.People on the diet tended to have lower.

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CDASH Standards and Conformance in Clinical Data Management

Quanticate

Clinical research thrives on standardised processes, and one crucial aspect is the adherence to the Clinical Data Acquisition Standards Harmonization (CDASH). First developed in 2006, CDASH plays a vital role in establishing harmonized standards for the collection and submission of data from clinical studies. CDASH is a pivotal component of the Clinical Data Interchange Standards Consortium (CDISC), which was established in 1997 to ensure data in clinical research to be accessible, interoperable

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Which pharmaceutical drugs have the most drug patents in Ireland?

Drug Patent Watch

This chart shows the drugs with the most patents in Ireland. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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Hospitals: Do You Know Where Your Controlled Substances Are?

FDA Law Blog: Biosimilars

By Larry K. Houck — Employee diversion of controlled substances from hospitals has been an issue since at least 1986 when I became a diversion investigator with the Drug Enforcement Administration (“DEA”). But there has been a recent string of large civil monetary settlements, some in the millions of dollars, to resolve allegations that hospitals’ non-compliance with the federal Controlled Substances Act (“CSA”) and DEA regulations allowed employees to divert staggering quantities of controlled

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Highlights from the 2024 CDISC + TMF EU Interchange in Berlin

Cytel

We’ve just wrapped up another successful CDISC + TMF EU Interchange event! This year’s event, which was attended by 352 people, featured parallel sessions dedicated to the Trial Master File (TMF) Reference Model, which has been a part of CDISC standard development initiatives for over a year now. This addition is crucial, as documentation is a serious and important aspect of our industry.

Trials 59
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J&J to buy Proteologix and its dual-targeting antibody drugs for $850M

BioPharma Drive: Drug Pricing

The deal is part of a plan by J&J to build a portfolio of “differentiated” bispecific antibodies, an increasingly popular area of drug development.

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HCP Perspectives: Access Challenges in Treating Diabetes & Obesity

Drug Channels

Today’s guest post is from Dr. Preeti Parikh, a practicing pediatrician and VP, Executive Medical Director at GoodRx. At the recent Publicis Health Media HealthFront event, Preeti hosted a dialogue on the main stage with Dr. Minisha Sood. They discussed new GoodRx research and had a candid discussion about their daily challenges in caring for patients—especially those living with diabetes and obesity.

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Buckle up, we’re headed to Informatica World 2024!

Perficient: Drug Development

On the Road to Vegas! We have our passes and are ready to hit the road for Informatica World 2024! This year’s conference is hosted in the heart of Las Vegas at Mandalay Bay Resort and Casino, May 20-23. Informatica World is an annual event that brings together over 2,000 experts to network, collaborate, and strategize new use cases on the Informatica platform.

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Clinical Trial Data Insights: Integrating Direct Data Capture with EDC

Crucial Data Solutions

How does your direct data capture (DDC) strategy fit with your electronic data capture (EDC) system? According to a recent. The post Clinical Trial Data Insights: Integrating Direct Data Capture with EDC appeared first on Crucial Data Solutions.

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PTSD Triples Odds for Teeth Grinding, Study Finds

Drugs.com

THURSDAY, May 16, 2024 -- People with post-traumatic stress disorder (PTSD) face more than triple the odds of bruxism, otherwise known as teeth grinding, a new study finds.The small study of 76 Brazilian adults (38 diagnosed with PTSD and 38.

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Happy Global Accessibility Awareness Day: Why It’s Everyone’s Celebration

Perficient: Drug Development

As we celebrate Global Accessibility Awareness Day (GAAD), it’s crucial to recognize that the significance of this day extends far beyond just those with disabilities. GAAD is a reminder of the importance of inclusivity and accessibility for all individuals in our digital age. In this article, we’ll explore why GAAD is a cause for celebration for everyone, regardless of ability, and how raising awareness can lead to a more inclusive and welcoming world.