Drug Discovery World
SEPTEMBER 6, 2024
Eli Lilly and biotechnology company HAYA Therapeutics have announced a multi-year agreement to apply HAYA’s RNA-guided regulatory genome platform to support preclinical drug discovery efforts in obesity and related metabolic conditions. The partners aim to identify multiple regulatory genome derived RNA-based drug targets to address these chronic conditions.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- An epidemic of high blood pressure is occurring in young adults and children in the United States, a pair of new studies show.Nearly a quarter of people ages 18 to 39 have high blood pressure, with readings above the.
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Drug Discovery World
SEPTEMBER 6, 2024
News round-up for 2-6 September by DDW Senior Digital Content Editor Diana Spencer. With the release of clinical study results that led some media titles to ask if semaglutide could be a ‘fountain of youth’, this week our news highlights focus on clinical trials at a variety of different stages. The top stories: Colorectal cancer study to be discontinued NuCana has revealed that the NuTide:323 colorectal cancer study is being discontinued following a pre-planned initial analysis and recommendati
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
The vision of people with a rare inherited condition that causes them to lose much of their sight early in childhood was 100 times better after they received gene therapy to address the genetic mutation causing it. Some patients even experienced a 10,000-fold improvement in their vision after receiving the highest dose of the therapy, according to researchers.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
SEPTEMBER 6, 2024
The Phase II NANOBRAINMETS trial of AGuIX has been validated by the Data Safety and Monitoring Board (DSMB) following a futility analysis scheduled after the enrolment and follow-up of 50% of patients in the study. The trial is being run by NH TherAguix, a biotechnology company developing novel nanomedicine solutions for precision radiotherapy in oncology, and is managed by the Dana Farber Cancer Institute.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- Saltwater nose drops can reduce the length of a kid’s cold by two days, a new study demonstrates.“We found that children using saltwater nose drops had cold symptoms for an average of six days, where those with usual care ha.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- A distinct brain pattern appears to make some people more likely to develop depression, a new study indicates.“Deep” functional MRI brain scans revealed that a brain feature called the salience network is nearly twice as lar.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
Some species of pterosaurs flew by flapping their wings while others soared like vultures, demonstrates a new study. Findings include a new pterosaur with a five-meter wingspan, which is one of the most complete pterosaurs ever recovered from Afro-Arabia.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- Gene therapy may restore vision to children and adults robbed of their sight by a rare inherited condition called Leber congenital amaurosis, researchers report.The illness is caused by mutations in the GUCY2D gene, which.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
Bacteria use their internal 24-hour clocks to anticipate the arrival of new seasons, according to research carried out with the assistance of an 'ice bucket challenge.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- People are encouraged to monitor their blood pressure at home, but many folks will find that household blood-pressure cuffs are literally a bad fit, a new study warns.For as many as 18 million U.S. adults -- nearly 7% of.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
Physicists have created a one-dimensional gas out of light. This has enabled them to test theoretical predictions about the transition into this exotic state of matter for the first time. The method used in the experiment by the researchers could be used for examining quantum effects.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- People who live in areas with more nighttime light pollution could be at increased risk of Alzheimer’s disease, particularly those in middle age, a new study says.Nightly light pollution is more strongly linked to A.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
Severe drought in the American Southwest and Mexico and more severe wet years in the Northeast are the modern norm in North America, according to new research -- and the analysis suggests these seasonal patterns will be more extreme in the future. The middle of the United States, meanwhile, can expect bigger swings between wetter wet periods -- high-rainfall years known as pluvials -- and drier summers through the rest of this century, the study predicts.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- As news of yet another senseless school shooting makes headlines, a new report finds the number of children who lose their lives to injury and gun violence has risen in almost all states since 2018. Rates of deaths caused.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
Researchers have discovered compelling evidence suggesting that the supermassive black hole at the center of our Milky Way galaxy, known as Sagittarius A* (Sgr A*), is likely the result of a past cosmic merger. The study builds on recent observations from the Event Horizon Telescope (EHT), which captured the first direct image of Sgr A* in 2022.
NIOSH Science Blog: Drugs
SEPTEMBER 6, 2024
Happy Respiratory Protection Week 2024! Another year provides another opportunity to highlight resources to support informed workplace respiratory protection practices. NIOSH has been at the forefront of this effort for decades, testing and approving respirators used in U.S. occupational settings while also striving to provide the science necessary to inform complex respiratory protection decisions.
Drug Discovery Today
SEPTEMBER 6, 2024
Secure your ticket to visit the biggest lab industry trade show in the UK.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
An AI-powered tool can distinguish dark matter's elusive effects from other cosmic phenomena, which could bring us closer to unlocking the secrets of dark matter.
Collaborative Drug
SEPTEMBER 6, 2024
We recently hosted our Sept 2024 Q3 Product Update Webinar, showcasing significant enhancements to the CDD Vault platform. The webinar covered four key modules: Curves, AI, Inventory Management, and Electronic Lab Notebook (ELN). Let's dive into the exciting updates for each module.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- As mpox continues to spread in Africa, Congolese authorities said Thursday that the first batch of vaccines have arrived in that country's capital. The shipment comes three weeks after the World Health Organization.
Science Daily: Pharmacology News
SEPTEMBER 6, 2024
A team models the atmospheres of distant planets using neural networks.
BioPharma Drive: Drug Pricing
SEPTEMBER 6, 2024
OrsoBio is advancing several weight loss medicines. Elsewhere, Boehringer Ingelheim pushed forward with a geographic atrophy drug and Vaxcyte raised $1.3 billion.
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- PFAS “forever chemicals” could cause pregnant women to experience long-term weight gain, increasing their risk of obesity in middle age, a new study warns.Women with higher levels of PFAS in their blood during early pre.
Perficient: Drug Development
SEPTEMBER 6, 2024
What Makes Salesforce a Leader in B2B E-Commerce: Key Takeaways from the Forrester Wave Q2 2024 Michael Affronti , Executive VP & GM of Commerce Cloud at Salesforce, recently expressed his excitement on LinkedIn about Salesforce being named a Leader in the Forrester Wave: Commerce Solutions for B2B, Q2 2024 report. This achievement highlights Salesforce’s reputation as a driving force in the B2B commerce industry, centered around innovative approach, robust platform, and customer-centr
BioPharma Drive: Drug Pricing
SEPTEMBER 6, 2024
New trial results could offer support for an expansion of Nucala’s label after U.S. regulators rejected GSK’s submission in 2018.
Fierce BioTech
SEPTEMBER 6, 2024
RWE Impact: When Empowered Patients Drive Pharma Outcomes pesurya Fri, 09/06/2024 - 11:33 Thu, 10/03/2024 - 11:00 Resource Type Webinar Leigh Ann Bruhn Arturo LoAIza-Bonilla MD Nico O'Kuinghttons Cathy Zaremba Promotion Start Mon, 09/09/2024 - 11:45 Promotion End Sun, 03/09/2025 - 11:45 Duration 60 Minutes Discover the transformative power of RWE. Join our webinar to learn how real-world evidence can revolutionize your pharma strategy.
Perficient: Drug Development
SEPTEMBER 6, 2024
Customer experience remains a top priority for organizations worldwide to gain and retain business. Even one unsatisfactory experience can cause customers to turn to a competitor, causing estimated losses of up $1.6 trillion in the United States annually. On the other hand, good omnichannel experiences turn connections into lasting experiences, brands into trusted partners, and customers into life-long advocates.
Drug Channels
SEPTEMBER 6, 2024
Today’s guest post comes from H. John Beardsley, Senior Vice President of Corporate Strategy at CoverMyMeds John discusses how the new maximum fair prices (MFPs) published by the Centers for Medicaid & Medicare Services (CMS) will affect medication affordability, formulary negotiations, evidence-based strategies, and other aspects of the market.
Quanticate
SEPTEMBER 6, 2024
The integration of Artificial Intelligence (AI) and Machine Learning (ML) in clinical trial design is beginning to reshape the pharmaceutical and medical research industries. Our article explores the methods by which AI and ML are modifying clinical trial design, with a focus on recent advancements and methodologies endorsed by regulatory bodies and used by industry leaders.
New Drug Approvals
SEPTEMBER 6, 2024
lazertinib CAS 1903008-80-9 554.655, C 30 H 34 N 8 O 3 2-PROPENAMIDE, N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)-2-PYRIMIDINYL)AMINO)-4-METHOXY-2-(4-MORPHOLINYL)PHENYL)- N-(5-((4-(4-((DIMETHYLAMINO)METHYL)-3-PHENYL-1H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)AMINO)-4-METHOXY-2-MORPHOLINOPHENYL)ACRYLAMIDE C-18112003-G GNS 1480 GNS-1480 GNS1480 JNJ-73841937-AAA YH 25448 YH-25448 YH25448 FDA APPROVED 8/19/2024 To treat non-small cell lung cancer, Lazcluze Ingredient UNII CAS InChI Key Lazerti
Drugs.com
SEPTEMBER 6, 2024
FRIDAY, Sept. 6, 2024 -- It seems like a kind of superpower, but scientists say they've used a common food dye to render the skin of a mouse transparent, revealing the workings of blood vessels and organs underneath.It's not yet clear if the.
BioPharma Drive: Drug Pricing
SEPTEMBER 6, 2024
J&J did not provide Auris Health with resources to achieve regulatory milestones after acquiring the robotics company in 2019, the judge found.
Alta Sciences
SEPTEMBER 6, 2024
Case Study—Nanosuspension Formulation to Maximize Potency for Preclinical Studies aasimakopoulos Fri, 09/06/2024 - 17:18 Publication case-study-nanosuspension-formulation.
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